Health
FDA approves allergy drug to lessen severity of reactions to peanuts, dairy, other foods
Food allergy sufferers have a new weapon in their fight against severe symptoms.
The U.S. Food and Drug Administration (FDA) has given the injectable Xolair (omalizumab) the green light for use in decreasing the risk of life-threatening reactions to certain foods.
Xolair was approved for “immunoglobulin E-mediated food allergy in certain adults and children 1 year or older,” the FDA announced on Feb. 16.
This is the first medication the FDA has approved to reduce allergic reactions after accidental exposure to several types of food, the agency stated.
GLUTEN-FREE LIFESTYLE: DEBUNKING MYTHS AND DECIDING IF THE DIET IS RIGHT FOR YOU
Robert A. Wood, M.D., was the principal investigator of the multicenter study that led to the FDA approval.
“Treatment options, aside from strict avoidance, have been very limited for the millions of Americans with severe food allergies,” Wood, director of the Division of Pediatric Allergy, Immunology and Rheumatology at Johns Hopkins University School of Medicine in Baltimore, Maryland, told Fox News Digital.
The FDA has given the injectable Xolair (omalizumab) the green light for use in decreasing the risk of life-threatening reactions to certain foods. (iStock)
“The lives of these patients and their families are often consumed by fear of accidental exposure to food allergens — and even with strict avoidance, accidental exposures are common.”
“The approval of Xolair for the treatment of food allergy will be very meaningful, and potentially even life-changing, for people with food allergies,” Wood added.
HERE’S WHY YOU’RE BLOATED — AND WHAT TO DO ABOUT THE COMMON DIGESTIVE CONDITION
Kenneth Mendez, president and CEO of the Asthma and Allergy Foundation of America (AAFA), a nonprofit headquartered in Maryland, was not involved in the medication research but spoke with Fox News Digital about the recent approval.
“The stress of living with food allergies can weigh heavily on people and their families, particularly when navigating events like children’s birthday parties, school lunches and holiday dinners with friends and family,” Mendez said.
“Given the growing prevalence of food allergies, this news offers hope to the many children and adults who may benefit from a new way to help manage their food allergies.”
Milk, eggs, fish, crustacean shellfish, wheat, soy, peanuts, and tree nuts account for the most serious allergic reactions in the U.S. (iStock)
Individuals must still avoid foods they’re allergic to, even if they take Xolair, the FDA noted in the announcement.
“This newly approved use for Xolair will provide a treatment option to reduce the risk of harmful allergic reactions among certain patients with IgE-mediated food allergies,” Kelly Stone, M.D., PhD, associate director of the Division of Pulmonology, Allergy and Critical Care in the FDA’s Center for Drug Evaluation and Research, said in an FDA news release.
“While it will not eliminate food allergies or allow patients to consume food allergens freely, its repeated use will help reduce the health impact if accidental exposure occurs.”
Risk reducer, not cure
Xolair, made by Genentech in California, is not approved for the immediate emergency treatment of allergic reactions. It is also not a substitute for current emergency treatments, the federal agency stated.
Such emergency treatments include doses of epinephrine and EpiPens to prevent anaphylaxis, which is a severe allergic reaction that can potentially be fatal, health experts told Fox News Digital.
Individuals must still avoid foods they are allergic to, even if they take Xolair, the FDA noted in the announcement. (iStock)
Nearly 6% of U.S. adults and children suffer from food allergies, according to the Centers for Disease Control and Prevention (CDC) — and more than 40% of children with food allergies in the U.S. have been treated in the emergency department.
Dr. Fred Davis, associate chair of emergency medicine at Northwell Health in New Hyde Park, New York, said he sees a number of allergic reactions from exposure to food.
“This drug may be able to lower that risk,” he told Fox News Digital.
“Remember that this is a preventative drug, not a medication to be used after exposure when one is having an acute allergic reaction,” Davis cautioned.
“This news offers hope to the many children and adults who may benefit from a new way to help manage their food allergies.”
“The recent FDA approval of Xolair for food allergies marks another important step forward for the 33 million Americans living with this condition,” Dr. Susan Schuval, chief of the Division of Pediatric Allergy/Immunology at Stony Brook Children’s Hospital on Long Island, New York, told Fox News Digital.
“Although Xolair is not a cure for food allergies, its use may lessen the risk of severe reactions from accidental food exposures. Patients will still need to practice food avoidance and carry epinephrine injectors,” Schuval said.
Emergency treatments include doses of epinephrine and EpiPens to prevent anaphylaxis, which is a severe allergic reaction that can potentially be fatal. (iStock)
As there is currently no cure for food allergies, the CDC recommends strict avoidance of any foods that cause them.
Milk, eggs, fish, crustacean shellfish, wheat, soy, peanuts, and tree nuts account for the most serious allergic reactions in the U.S., per the agency.
IgE-mediated food allergies — the most severe — occur when the body’s immune system mistakenly perceives a food particle as a harmful invader.
AVOID THESE FAD DIETS IN 2024; TRY THESE HEALTHY METHODS OF EATING INSTEAD
A type of antibody called immunoglobulin E (IgE) contributes to the immune response, which can include stomach issues, itching, hives or anaphylaxis, according to several health experts.
Xolair helps dampen this immune response by targeting certain receptors in the body.
“It is an injection that works on blocking IgE, reducing the risk of an allergic reaction, but needs to be taken regularly to work,” Davis told Fox News Digital.
Research behind the approval
The FDA’s approval decision was based on a study that explored the effectiveness and safety of Xolair in 168 participants ranging from babies to adults.
All participants were allergic to peanuts and at least two other foods, which included milk, wheat, egg, walnut, hazelnut or walnut.
A type of antibody called immunoglobulin E (IgE) contributes to the body’s immune response, which can include stomach issues, itching, hives or anaphylaxis. (iStock)
Participants received either Xolair or a placebo for 16 to 20 weeks.
Sixty-eight percent of those who received Xolair were able to tolerate the equivalent of 2½ peanuts without a moderate or severe allergic reaction, compared to 6% who took the placebo.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
Also among the participants who received the Xolair injections, 67% of people with egg allergies, 66% of people with milk allergies and 42% of people with cashew allergies were able to consume a single dose (1,000 milligrams or greater) of cashew, milk or egg protein without moderate to severe allergic symptoms.
The agency recommended that an individual should only start the medication in a health care setting equipped to manage anaphylaxis.
Patients should discuss with their health care provider whether Xolair is the right choice for them, experts said.
Fox News Digital reached out to the FDA for additional comment.
For more Health articles, visit www.foxnews.com/health.
Health
The Best Time To Take Turmeric for Weight Loss and How To Maximize Results
Use left and right arrow keys to navigate between menu items.
Use escape to exit the menu.
Sign Up
Create a free account to access exclusive content, play games, solve puzzles, test your pop-culture knowledge and receive special offers.
Already have an account? Login
Health
Doctor reveals what 30 days without alcohol does to the brain and body amid Dry January
NEWYou can now listen to Fox News articles!
After a season of bingeing and drinking, your body may feel like it needs a break from the party.
Dry January — a modern trend that challenges people to abstain from drinking for the first month of the year — has become a popular way to “detox” from the holidays and start the new year on a healthy note.
Research has linked alcohol to a variety of health conditions, ranging from hangovers to higher cancer risk.
5 POPULAR HANGOVER MYTHS THAT DON’T WORK AFTER HOLIDAY DRINKING, ACCORDING TO EXPERTS
In a recent podcast episode of “The Dr. Mark Hyman Show,” Dr. Mark Hyman, chief medical officer of Function Health, shared how 30 days of not drinking alcohol can transform health.
Hyman, who is based in Massachusetts, called Dry January a “powerful way to see in real time how alcohol affects nearly every system of your body and how quickly those systems can recover.”
Dry January has become a popular way to “detox” from the holidays and start the new year on a healthy note. (iStock)
Alcohol’s toll on the brain and body
Hyman acknowledged that most people drink to feel happier and more comfortable in social situations. This effect is caused by the main ingredient in alcohol, called ethanol, which can also have toxic effects.
Instead of stimulating the brain, alcohol slows it down and loosens inhibitions. “You feel more relaxed, more social, more confident, maybe you feel a little euphoric,” Hyman said.
Alcohol’s effect on the brain can also lead to poorer decisions and slower reflexes, the doctor cautioned.
Drinking alcohol can cause cognitive decline and brain fog, experts warn. (iStock)
Drinking also impacts the prefrontal cortex of the brain, which Hyman described as “the adult in the room,” responsible for judgment, planning and restraint. “It goes offline early in drinking, which explains why people feel freer or act impulsively when they drink,” he said.
Even moderate drinking can cause metabolic stress, inflammation, impaired detoxification and hormonal shifts, Hyman said, which can impact nearly every organ system in the body.
POPULAR WEIGHT-LOSS DRUGS COULD TAKE THE EDGE OFF YOUR ALCOHOL BUZZ, STUDY FINDS
Alcohol consumption has also been linked to an increased risk of cancer, metabolic dysfunction, gut microbiome disturbances and mitochondrial toxins.
It can also prevent the body from falling into REM sleep, which is the deep rest recovery period when the immune system cleans out the day’s toxins, according to Hyman.
Alcohol can impact deep rest and mental health, according to experts. (iStock)
Memory loss, cognitive decline, anxiety, sleep disruption, dementia and cardiovascular disease are all known risks of long-term alcohol use, as well as liver complications like fatty liver disease.
“Bottom line, alcohol taxes every major system in your body, especially your liver, your brain, your gut, your hormones,” Hyman said.
The effects of 30 days with no alcohol
The first week after your last drink, the body begins to detoxify and reset, according to Hyman. Blood sugar and cortisol stress hormones level out, and the liver begins to process a “backlog of toxins.” The body also re-hydrates and re-energizes.
The first 30 days with no alcohol allows the body to balance itself out. (iStock)
The second week, the gut and brain will begin to re-balance, as hormones like serotonin and dopamine stabilize, gut inflammation drops and the microbiome begins to heal. Cravings for sugar and alcohol will wane and mental clarity returns, the doctor said.
Week three is marked by further decreases in inflammation, fatty liver and blood pressure. This can be noticeable in the skin, as puffiness and redness are reduced. Mood also begins to stabilize, with lower anxiety levels.
DOCTORS REVEAL WHY ALCOHOL CAUSES ‘BOOZE BUTT’ AND HOW TO PREVENT IT ON NEW YEAR’S
In week four, the body experiences additional metabolic and immune benefits, Hyman shared, including more insulin sensitivity, which makes it easier to lose weight.
“You have a stronger immune response. You’re not getting sick as much. You have better deep sleep, balanced hormones, especially cortisol and testosterone,” he said. “And you see a big change in energy, confidence and focus.”
Abstaining from alcohol can help restore energy, according to experts. (iStock)
Dr. Pinchieh Chiang, a clinician at Circle Medical in San Francisco, said that Dry January isn’t a “detox,” but rather provides “feedback” from the body.
“It gives the body time to show people how it feels without alcohol. For many, that insight alone changes their relationship with drinking,” she said. “The biggest surprise isn’t what people give up, it’s how much better they feel.”
HIGHER STROKE RISK LINKED TO CONSUMING CERTAIN AMOUNT OF ALCOHOL, STUDY FINDS
The doctor confirmed that the first few days of not drinking may feel harder than expected, sometimes causing restlessness, cravings or disrupted sleep, but Dry January can ultimately change drinking habits for the remainder of the year.
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
After a full year without alcohol, Chiang noted that health improvements are more profound. “We see sustained improvements in blood pressure, liver function and inflammation,” she said. “Those changes directly affect long-term heart disease and stroke risk.”
The risks of ‘all or nothing’
Some experts warn that adopting the Dry January trend could strengthen the urge to drink more in the other months, noting that some drinkers may find more success by slowly consuming fewer drinks per week.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
Thomas Stopka, Ph.D., an epidemiologist and professor in the public health and community medicine department at Tufts University School of Medicine in Massachusetts, shared in a Futurity report that for some people, “damp January” may be more suitable.
One expert warned that not all drinkers should quit “cold turkey,” as it could lead to severe withdrawals. (iStock)
“Dry January is well-intentioned, and it may work really well for the people who can stick to it, maybe even beyond January,” he said. “Other people may be more inclined to cut down on alcohol consumption rather than quit drinking completely for the month.”
CLICK HERE FOR MORE HEALTH STORIES
Stopka noted that successful harm-reduction approaches “aim to be judgment free.”
“Substance use disorder is a disease,” he said. “It takes time to treat the disease and to stay connected to the continuum of care — from prevention to treatment initiation to sustained therapy, whether through medication, self-help, or individual therapy or group support.”
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
Those struggling with signs of alcohol use disorder should consult a medical professional for personalized guidance.
Fox News Digital reached out to several alcohol industry associations requesting comment.
Health
The Best Weight Loss Medications and Supplements in 2026
Use left and right arrow keys to navigate between menu items.
Use escape to exit the menu.
Sign Up
Create a free account to access exclusive content, play games, solve puzzles, test your pop-culture knowledge and receive special offers.
Already have an account? Login
-
Detroit, MI7 days ago2 hospitalized after shooting on Lodge Freeway in Detroit
-
Technology4 days agoPower bank feature creep is out of control
-
Dallas, TX5 days agoDefensive coordinator candidates who could improve Cowboys’ brutal secondary in 2026
-
Dallas, TX2 days agoAnti-ICE protest outside Dallas City Hall follows deadly shooting in Minneapolis
-
Iowa4 days agoPat McAfee praises Audi Crooks, plays hype song for Iowa State star
-
Delaware2 days agoMERR responds to dead humpback whale washed up near Bethany Beach
-
Health6 days agoViral New Year reset routine is helping people adopt healthier habits
-
Nebraska4 days agoOregon State LB transfer Dexter Foster commits to Nebraska