Health
COVID pandemic restrictions had 'alarming' impact on teenagers’ brains, new study finds
The pandemic’s negative effects on kids and teens — academically, socially and otherwise — have been shown in numerous studies, and now the latest long-term effect appears to be accelerated aging of young brains.
A team of researchers at the University of Washington studied 160 teens between the ages of 9 and 17. They had gathered data in 2018 for a different study on changes in brain structure during adolescence, but the COVID pandemic interrupted that research.
“Once the pandemic was underway, we started to think about which brain measures would allow us to estimate what the pandemic lockdown had done to the brain,” lead author Neva Corrigan, Ph.D., a research scientist at the University of Washington, said in a press release.
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“What did it mean for our teens to be at home rather than in their social groups — not at school, not playing sports, not hanging out?”
The researchers found that the pandemic caused teenage brains to age faster than normal.
The pandemic’s negative effects on kids’ and teens’ mental health have been shown in numerous studies. (iStock)
“The lifestyle changes due to the COVID-19 pandemic lockdowns appear to have affected brain development during adolescence, causing the brain to mature much faster than is typical,” Corrigan told Fox News Digital via email.
“This accelerated maturation was more widespread throughout the brain, and larger in magnitude, for females as compared to males.”
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On average, the young females’ brains aged 4.2 years faster than normal, and male brains were accelerated by 1.4 years.
Thirty regions in the female brain showed accelerated aging, compared to only two regions in the male brain, researchers found.
The findings were published in the Proceedings of the National Academy of Sciences on Sept. 9.
The researchers found that the pandemic caused teenage brains to age faster than normal. (iStock)
The researchers believe that the accelerated brain aging was due to the stress associated with the restrictive measures taken to curb COVID’s spread, Corrigan said.
“Accelerated development of the cerebral cortex during development has been well-established by previous research to be associated with chronic stress,” she noted.
Recommendations to parents
This study highlights the fact that teenagers’ brains are highly vulnerable to stressors in their environment, according to Corrigan.
“We recommend that parents of children who were teens during the pandemic stay connected to their teens, and also look out for signs of depression and anxiety, as accelerated cortical thinning increases the risk of developing these and other neuropsychiatric disorders,” she advised.
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“We also think parents should be aware that their teens’ social lives are very important to their brain development, and [they should] encourage healthy activities with peers.”
While these findings “seem alarming,” Corrigan said, it’s not known whether the accelerated aging will have long-term effects on continued brain development throughout the teens’ lives.
“It is not clear whether the cerebral cortex of these teens that showed accelerated maturation will return to a thickness that is more appropriate for their age with time, or whether these effects are permanent,” she told Fox News Digital.
It’s not known whether the accelerated aging will have long-term effects on continued brain development throughout the teens’ lives, a researcher noted. (iStock)
She also pointed out that “cortical thinning” is a natural process in aging and can actually allow the brain to function more efficiently.
“It is not clear that all the consequences of accelerated maturation are negative,” Corrigan added.
Potential limitations
The researchers acknowledged several limitations of the study, the first being its smaller sample size.
“Although we collected data from 160 teens prior to the lockdowns, and 130 teens after the lockdowns ended, larger samples are always better when conducting research,” Corrigan told Fox News Digital.
“What did it mean for our teens to be at home rather than in their social groups — not at school, not playing sports, not hanging out?”
“Also, since the study was not initially designed for the effects of the COVID pandemic, we did not collect the type of behavioral measures that would have allowed us to determine what exact lifestyle disruptions or stressors associated with the lockdowns might have been the greatest contributors to the stress experienced by the teens,” she said.
The researchers also only studied a limited age range, so they couldn’t determine whether the findings apply to other ages.
On average, the young females’ brains aged 4.2 years faster than normal, and male brains were accelerated by 1.4 years. (iStock)
“Finally, we do not know whether contraction of the COVID-19 virus itself may have contributed to these findings, although in the community from which our study sample was derived, we found no reports of a sex disparity in the contraction of the virus,” Corrigan said.
‘Downrange effects’
Dr. Brett Osborn, a Florida neurologist, was not involved in the study, but commented on the “detrimental consequences” of pandemic-related stress for teens.
“We recommend that parents of children who were teens during the pandemic stay connected to their teens, and also look out for signs of depression and anxiety,” a researcher said. (iStock)
“High levels of stress, often associated with elevated cortisol, can wreak havoc on the brain,” he told Fox News Digital.
Cortisol, the body’s primary stress hormone, is typically released by the adrenal glands during acute stress, Osborn explained, but it can become harmful when present at high levels for prolonged periods.
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“This chronic elevation is particularly damaging to brain structures like the hippocampus (the region associated with memory) and the prefrontal cortex, which is responsible for higher-level cognitive functions like decision-making and social behavior.”
“While the pandemic is over, this is not the end.”
Long-term exposure to high cortisol levels can negatively impact memory, emotional regulation, impulse control, focus and concentration, according to Osborn.
“Over time, these changes may predispose individuals to mental health disorders such as depression and anxiety, which are already known to be exacerbated by high cortisol levels,” he added.
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Overall, Osborn said, the study sheds light on “yet another downrange effect” of the COVID-19 pandemic.
The doctor added, “While the pandemic is over, this is not the end.”
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Doctor reveals what 30 days without alcohol does to the brain and body amid Dry January
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After a season of bingeing and drinking, your body may feel like it needs a break from the party.
Dry January — a modern trend that challenges people to abstain from drinking for the first month of the year — has become a popular way to “detox” from the holidays and start the new year on a healthy note.
Research has linked alcohol to a variety of health conditions, ranging from hangovers to higher cancer risk.
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In a recent podcast episode of “The Dr. Mark Hyman Show,” Dr. Mark Hyman, chief medical officer of Function Health, shared how 30 days of not drinking alcohol can transform health.
Hyman, who is based in Massachusetts, called Dry January a “powerful way to see in real time how alcohol affects nearly every system of your body and how quickly those systems can recover.”
Dry January has become a popular way to “detox” from the holidays and start the new year on a healthy note. (iStock)
Alcohol’s toll on the brain and body
Hyman acknowledged that most people drink to feel happier and more comfortable in social situations. This effect is caused by the main ingredient in alcohol, called ethanol, which can also have toxic effects.
Instead of stimulating the brain, alcohol slows it down and loosens inhibitions. “You feel more relaxed, more social, more confident, maybe you feel a little euphoric,” Hyman said.
Alcohol’s effect on the brain can also lead to poorer decisions and slower reflexes, the doctor cautioned.
Drinking alcohol can cause cognitive decline and brain fog, experts warn. (iStock)
Drinking also impacts the prefrontal cortex of the brain, which Hyman described as “the adult in the room,” responsible for judgment, planning and restraint. “It goes offline early in drinking, which explains why people feel freer or act impulsively when they drink,” he said.
Even moderate drinking can cause metabolic stress, inflammation, impaired detoxification and hormonal shifts, Hyman said, which can impact nearly every organ system in the body.
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Alcohol consumption has also been linked to an increased risk of cancer, metabolic dysfunction, gut microbiome disturbances and mitochondrial toxins.
It can also prevent the body from falling into REM sleep, which is the deep rest recovery period when the immune system cleans out the day’s toxins, according to Hyman.
Alcohol can impact deep rest and mental health, according to experts. (iStock)
Memory loss, cognitive decline, anxiety, sleep disruption, dementia and cardiovascular disease are all known risks of long-term alcohol use, as well as liver complications like fatty liver disease.
“Bottom line, alcohol taxes every major system in your body, especially your liver, your brain, your gut, your hormones,” Hyman said.
The effects of 30 days with no alcohol
The first week after your last drink, the body begins to detoxify and reset, according to Hyman. Blood sugar and cortisol stress hormones level out, and the liver begins to process a “backlog of toxins.” The body also re-hydrates and re-energizes.
The first 30 days with no alcohol allows the body to balance itself out. (iStock)
The second week, the gut and brain will begin to re-balance, as hormones like serotonin and dopamine stabilize, gut inflammation drops and the microbiome begins to heal. Cravings for sugar and alcohol will wane and mental clarity returns, the doctor said.
Week three is marked by further decreases in inflammation, fatty liver and blood pressure. This can be noticeable in the skin, as puffiness and redness are reduced. Mood also begins to stabilize, with lower anxiety levels.
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In week four, the body experiences additional metabolic and immune benefits, Hyman shared, including more insulin sensitivity, which makes it easier to lose weight.
“You have a stronger immune response. You’re not getting sick as much. You have better deep sleep, balanced hormones, especially cortisol and testosterone,” he said. “And you see a big change in energy, confidence and focus.”
Abstaining from alcohol can help restore energy, according to experts. (iStock)
Dr. Pinchieh Chiang, a clinician at Circle Medical in San Francisco, said that Dry January isn’t a “detox,” but rather provides “feedback” from the body.
“It gives the body time to show people how it feels without alcohol. For many, that insight alone changes their relationship with drinking,” she said. “The biggest surprise isn’t what people give up, it’s how much better they feel.”
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The doctor confirmed that the first few days of not drinking may feel harder than expected, sometimes causing restlessness, cravings or disrupted sleep, but Dry January can ultimately change drinking habits for the remainder of the year.
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After a full year without alcohol, Chiang noted that health improvements are more profound. “We see sustained improvements in blood pressure, liver function and inflammation,” she said. “Those changes directly affect long-term heart disease and stroke risk.”
The risks of ‘all or nothing’
Some experts warn that adopting the Dry January trend could strengthen the urge to drink more in the other months, noting that some drinkers may find more success by slowly consuming fewer drinks per week.
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Thomas Stopka, Ph.D., an epidemiologist and professor in the public health and community medicine department at Tufts University School of Medicine in Massachusetts, shared in a Futurity report that for some people, “damp January” may be more suitable.
One expert warned that not all drinkers should quit “cold turkey,” as it could lead to severe withdrawals. (iStock)
“Dry January is well-intentioned, and it may work really well for the people who can stick to it, maybe even beyond January,” he said. “Other people may be more inclined to cut down on alcohol consumption rather than quit drinking completely for the month.”
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Stopka noted that successful harm-reduction approaches “aim to be judgment free.”
“Substance use disorder is a disease,” he said. “It takes time to treat the disease and to stay connected to the continuum of care — from prevention to treatment initiation to sustained therapy, whether through medication, self-help, or individual therapy or group support.”
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Those struggling with signs of alcohol use disorder should consult a medical professional for personalized guidance.
Fox News Digital reached out to several alcohol industry associations requesting comment.
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