Connect with us

Health

Common menopause medication might prevent breast cancer while treating hot flashes

Published

on

Common menopause medication might prevent breast cancer while treating hot flashes

NEWYou can now listen to Fox News articles!

A drug intended to treat menopause symptoms could double as breast cancer prevention.

Advertisement

New research from Northwestern University in Illinois found that Duavee, a Pfizer-made drug, “significantly reduced” breast tissue cell growth, which is a major indicator of cancer progression.

A phase 2 clinical trial included 141 post-menopausal women who had been diagnosed with ductal carcinoma in situ (DCIS), also known as stage 0 breast cancer, according to a press release from Northwestern.

PROSTATE CANCER DRUG NOW AVAILABLE TO MORE PATIENTS WITH AGGRESSIVE FORM OF DISEASE

This non-invasive breast cancer affects more than 60,000 American women each year, often leading to an outcome of invasive breast cancer.

The women were separated into two groups — one received Duavee and the other took a placebo for a month before undergoing breast surgery.

Advertisement

A drug intended to treat menopause symptoms could double as breast cancer prevention, new research suggests. (iStock)

Duavee is a conjugated estrogen/bazedoxifene (CE/BZA) drug, which combines estrogen with another medication that minimizes the potential harmful side effects of the hormone.

“The key takeaway from the study is that CE/BZA slows the growth (proliferation) of cells in milk ducts of DCIS that expressed the estrogen receptor significantly more than placebo,” Dr. Swati Kulkarni, lead investigator and professor of breast surgery at Northwestern University Feinberg School of Medicine, told Fox News Digital.

EXPERIMENTAL WOMEN’S CANCER DRUG BOOSTS SURVIVAL RATES IN NOTABLE STUDY

Another major finding is that the quality of life did not differ significantly between the two groups, but patients who took the CE/BZA reported fewer hot flashes during the study, she noted.

Advertisement

“This would be expected, as the drug is FDA-approved to treat hot flashes.”

“What excites me most is that a medication designed to help women feel better during menopause may also reduce their risk of invasive breast cancer.”

Kulkarni presented the study last week at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago. 

The findings are preliminary and have not yet been published in a medical journal.

“What excites me most is that a medication designed to help women feel better during menopause may also reduce their risk of invasive breast cancer,” said the doctor, who is also a Northwestern Medicine breast surgeon.

Advertisement

Ductal carcinoma in situ (DCIS), also known as stage 0 breast cancer, affects more than 60,000 U.S. women each year. (iStock)

Women who face a higher risk of breast cancer — including those who have experienced “high-risk lesions” — and who also have menopausal symptoms are most likely to benefit from the drug, according to Kulkarni. 

“These women are typically advised against standard hormone therapies, leaving them with few menopausal treatment options,” the release stated. 

Study limitations

The researchers said they are “encouraged” by these early results, but more research is required before the medication can be considered for approval as a breast cancer prevention mechanism.

Advertisement

“Our findings suggest that CE/BZA may prevent breast cancer, but larger studies with several years of follow-up are needed before we would know this for sure,” Kulkarni told Fox News Digital.

Post-menopausal patients who took the CE/BZA reported fewer hot flashes during the study. (iStock)

Dr. Sheheryar Kabraji, chief of breast medicine at the Roswell Park Comprehensive Cancer Center in Buffalo, New York, was not involved in the study but commented on the findings.

“While intriguing, this study is highly preliminary, and more research will be needed before we can conclude that conjugated estrogen/bazedoxifene (CD/BZA), a form of the hormone estrogen commonly prescribed to address symptoms of menopause, prevents invasive breast cancer or is effective at reducing cancer risk,” she told Fox News Digital.

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Advertisement

Kabraji also noted that the study focused on reducing levels of one specific protein, “which does not always predict reduced recurrence of breast cancer.” 

“This study did not directly show that CE/BZA treatment reduces the risk of DCIS recurrence or development of invasive cancer,” she noted. 

“While intriguing, this study is highly preliminary.”

“Importantly, however, patients who received this therapy experienced no worsening of quality of life, and saw improvement in vasomotor symptoms, such as hot flashes. If found to be effective in preventing breast cancer, CE/BZA is likely to have fewer side effects than current medications used for breast cancer prevention.”

For more Health articles, visit www.foxnews.com/health

Advertisement

Lead researcher Kulkarni emphasized that this medication is not for the treatment of invasive breast cancer or DCIS.

“Right now, we can say that women who are concerned about their risk of developing breast cancer can consider this medication to treat their menopausal symptoms,” she added.

Advertisement

Health

How much red meat is too much? Experts weigh in on food pyramid updates

Published

on

How much red meat is too much? Experts weigh in on food pyramid updates

NEWYou can now listen to Fox News articles!

The release of an updated food pyramid this week has sparked mixed reactions from doctors and dietitians.

One of the most noteworthy shifts in the 2025-2030 Dietary Guidelines for Americans — announced by HHS officials during a Jan. 7 press conference at the White House — is a greater emphasis on “high-quality proteins,” including red meat and eggs, as well as full-fat dairy.

The new guidelines focus on “real, whole, nutrient-dense foods,” and a dramatic reduction in highly processed foods, added sugars, refined carbohydrates and unhealthy fats.

HEALTH EXPERTS REACT AS ANDREW HUBERMAN BACKS TRUMP ADMIN’S NEW FOOD PYRAMID

Advertisement

“Protein and healthy fats are essential and were wrongly discouraged in prior dietary guidelines,” Health Secretary Robert F. Kennedy Jr. said during the press conference. “We are ending the war on saturated fats.”

Nick Norwitz, a Harvard- and Oxford-trained researcher known for his work in metabolic health, shared his reaction to the new guidelines.

The release of an updated food pyramid this week has sparked mixed reactions from doctors and dietitians. (realfood.gov)

Despite how the new pyramid is presented, he noted, the actual guidelines for saturated fat consumption haven’t changed, as they still state that, “in general, saturated fat consumption should not exceed 10% of total daily calories.”

The intake of unprocessed whole foods rich in saturated fat, especially dairy fat, tends to be associated with improved health outcomes, according to Norwitz.

Advertisement

RED MEAT CAN HELP YOUR MOOD IF PART OF A HEALTHY, BALANCED DIET, STUDY SUGGESTS

“Full-fat dairy — especially cheese, for example — tends to be associated with lower BMI, reduced rates of diabetes and even reduced dementia risk,” he told Fox News Digital. “There are, of course, nuances — but ‘ending the war’ on saturated fat seems reasonable.”

Risks vary, experts say

Experts cautioned about the potential health risks of exceeding the recommended intake of saturated fat, including higher rates of LDL “bad” cholesterol, which is known to increase the risk of cardiovascular disease.

“The recommendation to limit saturated fat to 10% of total calories is based on the research showing that higher rates increase LDL cholesterol and associated risks for cardiovascular disease,” Sherry Coleman Collins, a food allergy dietitian and expert from the Atlanta metropolitan area, told Fox News Digital. 

One of the most noteworthy shifts in the 2025-2030 Dietary Guidelines for Americans is a greater emphasis on “high-quality proteins” — including red meat and eggs — as well as full-fat dairy. (iStock)

Advertisement

Nutrition should be personalized and is dependent on multiple factors, she said, including age, gender, activity level and genetic risk factors.

“The total saturated fat an individual might safely consume is influenced by their size and total calorie needs, as well as potentially genetic differences,” Coleman Collins said.

Norwitz agreed, adding that “the specific food source and interaction with the unique host and their broader dietary context should take the spotlight.”

Dr. Pooja Gidwani, a double board-certified doctor of internal medicine and obesity medicine in Los Angeles, pointed out that not everyone has the same “tolerance” for saturated fats.

“If increasing saturated fat leads to a meaningful rise in LDL cholesterol or ApoB (Apolipoprotein B, a protein found on the surface of certain cholesterol-carrying particles in the blood), that intake level is excessive for that individual, regardless of improvements in weight or glucose metrics,” she said.

Advertisement

TRUMP ADMIN’S NEW NUTRITION GUIDELINES TARGET ULTRA-PROCESSED FOODS, EASE UP ON RED MEAT AND SATURATED FATS

“This personalized approach becomes increasingly important in midlife and beyond, when cardiovascular disease becomes the dominant driver of morbidity and mortality and when tolerance for cumulative atherogenic (artery-clogging) exposure is lower.”

For those who need to reduce LDL cholesterol or have a higher cardiovascular risk, the American Heart Association recommends an even lower amount of saturated fats — less than 6% of total daily calories.

Experts cautioned about the potential health risks of exceeding the recommended intake of saturated fat, including higher rates of LDL “bad” cholesterol. (iStock)

Gidwani also cautioned that diets emphasizing saturated fat could crowd out fiber and unsaturated fats, “both of which play independent roles in cholesterol clearance, insulin sensitivity, gut health and inflammation.”

Advertisement

“Saturated fat-heavy patterns are also calorie-dense, which can quietly undermine long-term weight management if intake is not carefully regulated,” she added.

Not all saturated fats are equal, experts say

The effects of saturated fat depend on what specific foods are being consumed, according to experts.

“I would recommend choosing minimally processed or unprocessed forms of foods,” said Tanya Freirich, a registered dietitian nutritionist in Charlotte, North Carolina. “For example, in place of a hot dog — which has additives, nitrites, sodium and fillers — consuming a chicken thigh would be a much better choice.”

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

Gidwani reiterated that the amount of processing plays a big role.

Advertisement

“Processed meats are consistently associated with worse cardiometabolic outcomes and represent the clearest category to limit,” she said. “The risk here is not only saturated fat, but also sodium load, preservatives and the broader dietary pattern they tend to accompany.”

“Full-fat dairy — especially cheese, for example — tends to be associated with lower BMI, reduced rates of diabetes and even reduced dementia risk,” an expert told Fox News Digital. (iStock)

Unprocessed red meat, the doctor said, can fit into an overall healthy diet in smaller amounts, particularly when consumed alongside fiber-rich plants and minimally processed foods.

“However, from a longevity perspective, it should be viewed as optional rather than foundational, especially for individuals with elevated cardiovascular risk,” she added.

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Advertisement

When it comes to dairy, Gidwani noted that fermented options are “metabolically more favorable” than butter or cream.

“However, saturated fat from dairy is still not necessary to prioritize for metabolic health or longevity,” she said. “Excessive reliance on dairy fat can displace healthier fat sources without offering clear long-term benefit.”

CLICK HERE FOR MORE HEALTH STORIES

Overall, the doctor recommends unsaturated fat sources, including extra virgin olive oil, nuts, seeds, avocado and omega-3-rich fish, as primary dietary fats.

“These consistently support lipid profiles, insulin sensitivity and vascular health,” Gidwani said. “Saturated fat can exist within a balanced diet, but it should remain secondary rather than emphasized.”

Advertisement

Why the big picture matters

Saturated fat is just one piece of a much wider nutrition puzzle, the experts agreed.

Unprocessed red meat can fit into an overall healthy diet in smaller amounts, particularly when consumed alongside fiber-rich plants and minimally processed foods, one expert said. (iStock)

“Our heart health is not determined by one type of fat or one type of cholesterol, but the sum of many parts — our entire diet, our exercise habits, our stress and so much more,” Freirich said.

She recommends consulting a registered dietitian for guidance on unique dietary needs based on age, gender, activity level and medical history.

“Our heart health is not determined by one type of fat or one type of cholesterol, but the sum of many parts — our entire diet, our exercise habits, our stress and so much more,” said an expert.  (iStock)

Advertisement

New Jersey-based dietitian Erin Palinski-Wade, author of “2-Day Diabetes Diet,” added that the message should be to focus more on overall patterns.

That means “plenty of fiber-rich plants, lean protein at every meal (including those that also contain fiber, such as nuts and seeds) and a reduction in overall intake of added sugars.”

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

“That change will drive true health improvements,” she said.

Advertisement
Continue Reading

Health

The Wegovy Pill Is Here: See the Cost and How Much Weight You Can Lose

Published

on

The Wegovy Pill Is Here: See the Cost and How Much Weight You Can Lose


Advertisement


No Shots Required! Doctors Say the New $25 a Month Wegovy Pill Works | Woman’s World




















Advertisement











Advertisement




Use left and right arrow keys to navigate between menu items.


Use escape to exit the menu.

Advertisement

Continue Reading

Health

Missing sleep may take a hidden toll on your brain and longevity, research reveals

Published

on

Missing sleep may take a hidden toll on your brain and longevity, research reveals

NEWYou can now listen to Fox News articles!

Missing out on adequate sleep could be taking years off your life.

New research from the Oregon Health & Science University (OHSU), published in the journal Sleep Advances, found that poor sleep may shorten life expectancy more than other lifestyle factors like diet, exercise and loneliness.

The researchers analyzed nationwide CDC survey data, identifying trends associated with average life expectancy by county, according to a press release.

NEW HEALTH WARNING ISSUED OVER POPULAR SLEEP AID MILLIONS TAKE NIGHTLY

Advertisement

The study found that lack of adequate sleep led to higher mortality risk in every U.S. state and was the top behavioral driver compared to other factors, only behind smoking.

Senior study author Andrew McHill, Ph.D., associate professor and director of the Sleep, Chronobiology, and Health Laboratory in the OHSU School of Nursing, noted in a statement that he did not expect sleep to be “so strongly correlated” to life expectancy.

Poor sleep is directly correlated with shorter life expectancy, the study reveals. (iStock)

“We’ve always thought sleep is important, but this research really drives that point home: People really should strive to get seven to nine hours of sleep, if at all possible,” he said.

“This research shows that we need to prioritize sleep at least as much as we do [in] what we eat or how we exercise.”

Advertisement

CLICK HERE FOR MORE HEALTH STORIES

In a previous interview with Fox News Digital, Dr. Daniel Amen, psychiatrist and owner of Amen Clinics in California, emphasized how important sleep is for brain function and longevity.

Researchers suggest people should prioritize sleep just as much as diet and exercise. (iStock)

“Sleep is so important,” he said. “When you sleep, your brain cleans and washes itself. And if you don’t sleep seven to nine hours at night, your brain looks older than you are — there’s less blood flow, and it increases inflammation in the brain.”

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Advertisement

“Your brain doesn’t have enough time to get rid of the toxins that build up during the day.”

Lack of adequate sleep can lead to poor decisions and foster toxic cycles, the doctor warned. 

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

“If your brain has less activity in the front part, not only are you tired, but you’re also hungrier, and you’re more likely to not make the best decisions,” he said. 

“Which, of course, will stress you out, and then you won’t sleep well the next night.”

Advertisement

A doctor suggests being “purposeful” about going to bed and waking up each day. (iStock)

One small change to promote longevity and brain health is to try getting to bed 15 minutes earlier, Amen suggested.

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

“Really be purposeful about not being distracted by Netflix or your phone,” he said.

“And when you get up in the morning, say to yourself, ‘Today is going to be a great day.’ The more positive you are, the better your brain.”

Advertisement

Continue Reading
Advertisement

Trending