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AI detects ovarian cancer better than human experts in new study

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AI detects ovarian cancer better than human experts in new study

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For the nearly 20,000 women in the U.S. who receive an ovarian cancer diagnosis each year, artificial intelligence is emerging as a potentially life-saving tool.

In a new study led by researchers at Karolinska Institutet in Sweden, AI models did a better job of detecting ovarian cancer than human doctors. 

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The research, which was published in Nature Medicine, tested an AI model’s ability to distinguish between benign and malignant lesions on the ovaries, according to a press release.

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The AI model was trained on more than 17,000 ultrasound images from 3,652 patients across 20 hospitals in eight countries, the release stated.

“High-quality diagnostics can become more accessible, particularly in regions with limited access to experienced examiners,” said a study author. (iStock)

The AI model achieved an accuracy rate of 86% for detecting ovarian cancer, compared to 82% for human experts and 77% for those with less expertise.

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“I was surprised that the AI models outperformed all 33 of the expert examiners,” study author Elisabeth Epstein, a professor at the Department of Clinical Science and Education at Karolinska Institutet, told Fox News Digital.

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Ovarian tumors are common and “often detected by chance,” according to Epstein. 

“Our study demonstrates that AI-driven diagnostic support can significantly improve ovarian cancer diagnosis by enhancing triage efficiency, reducing diagnostic errors and addressing the shortage of expert examiners,” she said in a statement to Fox News Digital. 

The AI model achieved an accuracy rate of 86% for detecting ovarian cancer, compared to 82% for human experts and 77% for those with less expertise. (iStock)

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“High-quality diagnostics can become more accessible, particularly in regions with limited access to experienced examiners,” Epstein went on. 

“This will help reduce waiting times, avoid unnecessary interventions and facilitate earlier cancer detection, ultimately improving patient outcomes and ensuring more accurate diagnoses.”

AI could also reduce the need for referrals as well as the chances of misdiagnosis, the researchers noted.

“I was surprised that the AI models outperformed all 33 of the expert examiners.”

Dr. Brian Slomovitz, director of gynecologic oncology and co-chair of the Cancer Research Committee at Mount Sinai Medical Center in Florida, noted that screening and early detection of ovarian cancer is the “holy grail” to reduce deaths from this disease.

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“This large retrospective trial clearly demonstrates that there may be a role in incorporating AI-driven support to better interpret ultrasound findings in patients with a pelvic mass,” Slomovitz, who was not involved in this particular study, told Fox News Digital. 

“This, by itself, increases the accuracy of the radiologic findings by both decreasing the false positive rate (leading to unnecessary surgeries) and decreasing the false negative rate (missing cases of cancer).”

Screening and early detection of ovarian cancer is the “holy grail” to reduce deaths from this disease, one oncologist noted. (iStock)

There are other ways to evaluate ovarian cancer patients beyond radiology scans, the doctor noted.

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“Menopausal status, presence or absence of symptoms, and blood test results are some other factors used to determine which patients may or may not need surgery,” Slomovitz said. “It would be great if these factors could be incorporated into the AI modeling.”

OVARIAN CANCER SIGNS, SYMPTOMS, DIAGNOSIS AND TREATMENT OPTIONS

In addition to showing improved accuracy of ultrasound analysis, the AI technology will need to demonstrate a survival benefit in order to gain widespread use, he added.

“I am optimistic that artificial intelligence will be a part of the armamentarium used to improve the care we offer to our patients.”

“I am optimistic that artificial intelligence will be a part of the armamentarium used to improve the care we offer to our patients,” an oncologist said. (iStock)

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Dr. Harvey Castro, a Dallas, Texas-based board-certified emergency medicine physician and national speaker on AI in health care, agreed that the tech has the potential to improve cancer diagnostics, but cautioned that limitations remain.

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“The AI relies on diverse, high-quality data, and bias could limit effectiveness,” he told Fox News Digital.

“It’s also not fully validated for routine clinical use, and transparency and regulatory concerns remain unresolved.”

Castro reiterated that additional research is needed to determine how well AI adapts to real-world settings, the long-term impact on health care costs and outcomes, and whether the tech will be able to handle diverse populations and different clinical environments.

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The researchers also acknowledged the potential limitations of the study.

“It is not a prospective study, so additional data is needed to know how it would perform in a real clinical setting,” Epstein told Fox News Digital. 

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The team is planning to soon begin clinical studies at Stockholm South Hospital in Sweden, she added.

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“It is still the physician who remains responsible for the patient’s diagnosis and treatment.”

Epstein noted that AI should only be used as a diagnostic support and not a replacement for human physicians. 

“It is still the physician who remains responsible for the patient’s diagnosis and treatment,” she stated. 

      

The Karolinska Institutet research team collaborated with the KTH Royal Institute of Technology. Funding was provided by the Swedish Research Council, the Swedish Cancer Society, the Stockholm Regional Council, the Cancer Research Funds of Radiumhemmet and the Wallenberg AI, Autonomous Systems and Software Program (WASP), according to the release.

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Scientists make startling discovery when examining prostate cancer tissue

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Scientists make startling discovery when examining prostate cancer tissue

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Small fragments of plastic were found in the tumors of most prostate cancer patients, according to a new study from NYU Langone Health. 

In past studies, microplastics have been found in almost every human organ and in bodily fluids, but their impact on human health still isn’t fully understood.

The researchers analyzed tissue samples from 10 patients with prostate cancer who underwent surgery to remove the entire organ. 

Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples, according to the study press release.

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In past studies, microplastics were found in almost every single human organ along with bodily fluids, even the placenta. (iStock)

The cancerous tissue contained on average more than double the amount of plastic as healthy prostate tissue samples, the study found. This equates to about 40 micrograms of plastic per gram of tissue compared to 16 micrograms.

Researchers avoided contaminating the samples with other plastics by substituting standard tools with those made of aluminum, cotton and other non-plastic material, the release noted.

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The scientists say this is the first direct evidence linking microplastics to prostate cancer.

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“By uncovering yet another potential health concern posed by plastic, our findings highlight the need for stricter regulatory measures to limit the public’s exposure to these substances, which are everywhere in the environment,” said senior study author Vittorio Albergamo, assistant professor in the department of pediatrics at NYU Grossman School of Medicine, in the release.

Using visuals of both benign samples and tumor samples, as well as specialized equipment, the scientists identified plastic particles in 90% of the tumor samples and 70% of benign tissue samples. (iStock)

The study findings were presented during the American Society of Clinical Oncology’s Genitourinary Cancers Symposium in San Francisco on Feb. 26.

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“What is most striking is not that microplastics were detected, but that they were found embedded within tumor tissue itself,” Dr. David Sidransky, oncologist and medical advisor at SpotitEarly, a startup that offers an at-home breath-based test to detect early-stage cancer, told Fox News Digital.

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“While complete avoidance is unrealistic, people can take practical steps to reduce exposure.”

“We already know microplastics are present in water, air, blood and even placental tissue. Their detection in prostate tumors suggests systemic distribution and long-term bioaccumulation,” added Maryland-based Sidransky, who was not involved in the study.

Study limitations

Albergamo cautioned that a larger sample is needed to confirm the findings. Additionally, Sidransky noted that the presence of microplastics alone does not prove they cause cancer.

“Tumors can act as ‘biologic sinks,’ meaning they may accumulate circulating particles simply because of altered vasculature and permeability,” he said.

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A key unanswered question, according to the doctor, is whether microplastics are biologically active in ways that “promote DNA damage, immune modulation or chronic inflammation within the prostate.”

About one in eight men in the U.S. will be diagnosed with prostate cancer at some point in their lifetime, according to the Centers for Disease Control and Prevention.

The most actionable step men can take is appropriate screening and early detection, according to doctors. (iStock)

For those concerned about microplastics, Sidransky offered some insights.

“I believe the appropriate response is curiosity, not panic, and a commitment to understand more,” he said.

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“While complete avoidance is unrealistic, people can take practical steps to reduce exposure, such as minimizing heating food in plastic containers, reducing bottled water consumption when possible, and favoring glass or stainless steel alternatives.”

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The most actionable step men can take, however, is getting appropriate screenings to help ensure early detection, according to the doctor. Screening discussions should be individualized based on age, family history and other risk factors.

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How a Vegan Diet Can Help You Lose Weight 8X Faster

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Cancer-linked herbicide in the spotlight after controversial order: ‘Toxic by design’

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Cancer-linked herbicide in the spotlight after controversial order: ‘Toxic by design’

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There has been a shake-up in the Make America Healthy Again movement regarding glyphosate, a widely used herbicide that has been the subject of significant controversy.

The debate follows an executive order signed by President Donald Trump that ensures an adequate supply of elemental phosphorus and glyphosate-based herbicides related to national defense.

MAHA supporters have previously pushed a pesticide-free agenda, warning of potential health harms caused by glyphosate.

Dr. Marc Siegel, Fox News senior medical analyst, said he believes there is sufficient evidence linking glyphosate to neurodegenerative diseases, including ALS, Parkinson’s and multiple sclerosis, to warrant limiting exposure.

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President Donald Trump signed an executive order that ensures an adequate supply of elemental phosphorus and glyphosate-based herbicides related to national defense. (AP Photo/Charlie Neibergall)

“With Parkinson’s, this association appears to be due to the gut, vagus nerve and brain axis, where the exposure affects the microbiome in the gut, which then ascends slowly up to the brain, causing the neurodegenerative disease years later,” Siegel told Fox News Digital.

“There is also a growing association being found between high-dose glyphosate or occupational exposure and metabolic disorders, liver disease and some cancers, specifically lymphoma.”

He added, “Growing research backs this. I favor limiting it.”

“When we apply them across millions of acres and allow them into our food system, we put Americans at risk.”

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Studies have shown that glyphosate, which is used in products such as Roundup, owned by Monsanto, could raise cancer risk.

In one University of Washington study published in the journal Mutation Research, researchers found that exposure to it increased the risk of non-Hodgkin lymphoma by 41%.

The nonprofit Investigate Midwest, which analyzed data from both the U.S. Geological Survey and the National Cancer Institute, also recently found that pesticides may contribute to cancer rates.

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Among the top 500 counties for per-square-mile pesticide use, more than 60% had cancer rates above the national average of 460 cases per 100,000 people, according to the report.

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Investigate Midwest, which is based in Illinois, interviewed more than 100 farmers, environmentalists, lawmakers and scientists as part of a partnership with the Pulitzer Center’s StoryReach U.S. Fellowship.

Among the top 500 counties for per-square-mile pesticide use, more than 60% had cancer rates above the national average of 460 cases per 100,000 people, according to one study. (iStock)

Iowa, which used 53 million pounds of pesticides last year, holds the nation’s title for second-highest cancer rate.

Bill Billings, a resident of Red Oak, Iowa, was diagnosed with cancer in 2014. 

“The cancer specialist said, very directly, (my) cancer is a result of being exposed to chemicals,” Billings said in the report.

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Kelly Ryerson, founder of Glyphosate Facts and owner of the Instagram account @glyphosategirl, told Fox News Digital her journey researching the herbicide began with her own health struggles.

Ryerson, who is based in California, previously struggled with chronic illness and autoimmune issues, which she said improved when she stopped eating gluten. 

Iowa, which used 53 million pounds of pesticides last year, holds the nation’s title for second-highest cancer rate. (iStock)

After attending a medical conference at Columbia University’s Celiac Disease Center, Ryerson began to question modern farming practices rather than the gluten itself.

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“A lot of times, farmers are spraying Roundup on our grains right before harvest to facilitate an easier harvest,” she said. “After that easier harvest, because everything’s dry at the same time, those crops go directly to the mill and may end up in our food supply, at alarmingly high levels.”

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In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization framework, classified glyphosate as “probably carcinogenic to humans.”

The classification was based on limited evidence of cancer in humans (notably non-Hodgkin lymphoma in some studies) and sufficient evidence in experimental animals.

“President Trump’s executive order reinforces the critical need for U.S. farmers to have access to essential, domestically produced crop protection tools, such as glyphosate,” a Monsanto spokesperson said. (Wolf von Dewitz/picture alliance via Getty Images)

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A spokesperson for Monsanto told Fox News Digital it will comply with Trump’s order to produce glyphosate and elemental phosphorus.

“President Trump’s executive order reinforces the critical need for U.S. farmers to have access to essential, domestically produced crop protection tools, such as glyphosate,” the spokesperson said.

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HHS Secretary Robert F. Kennedy Jr. has long been a vocal critic of Roundup, working with his legal team in 2018 to award $289 million to a man who alleged the weed killer caused his non-Hodgkin lymphoma, according to reports.

Following backlash to Trump’s executive order, Kennedy said he supports the order but acknowledged that “pesticides and herbicides are toxic by design, engineered to kill living organisms.”

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“When we apply them across millions of acres and allow them into our food system, we put Americans at risk,” he posted on X. “Chemical manufacturers have paid tens of billions of dollars to settle cancer claims linked to their products, and many agricultural communities report elevated cancer rates and chronic disease.”

Fox News Digital reached out to the White House for comment.

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