Connect with us

Health

Aggressive brain cancer may respond to high-dose vitamin therapy, study suggests

Published

on

Aggressive brain cancer may respond to high-dose vitamin therapy, study suggests

NEWYou can now listen to Fox News articles!

High-dose vitamin B3 (niacin) may enhance immune activity and improve short-term disease control in glioblastoma when added to standard therapy, according to early preclinical studies.

Glioblastoma is a highly aggressive, fast-growing brain cancer that develops from cells in the brain and spinal cord.

In previous laboratory experiments in mice, niacin was shown to extend survival. Researchers at the University of Calgary aimed to determine whether that same benefit extended to humans.

COMMON BLOOD PRESSURE PILL COULD MAKE CERTAIN CANCER TREATMENTS MORE POWERFUL

Advertisement

The trials included 24 patients with glioblastoma, which has a median survival of roughly 12 to 18 months. 

Six months after receiving niacin in addition to standard treatments (surgery, radiation and chemotherapy), 82% of the patients showed no disease progression, compared to the typical 54%, according to the study’s press release.

Left to right: Edward (Ed) Waldner (study participant), Dr. Wee Yong, PhD, (scientist), Dr. Gloria Roldan Urgoiti, MD, (oncologist) (Riley Brandt, University of Calgary)

Niacin was also found to restore function in weakened immune cells, improving their ability to target and destroy tumor cells.

The findings, including the 28% improvement in disease progression, were published in the Journal of Neuro-Oncology.

Advertisement

CLICK HERE FOR MORE HEALTH STORIES

“Normally, the immune system will try to counter and prevent tumor growth; however, this brain cancer suppresses the immune system,” said study author Dr. Wee Yong, PhD, a neuroscientist who studies immune responses in the brain, in the release. “Niacin treatment rejuvenates immune cells so they can do what they are supposed to do: attack and kill the cancer cells. I see it as an ongoing ‘battle for the brain.’”

Looking ahead, the team plans to enroll an additional 24 patients by the end of 2026 or early 2027 for the next phase of the trial, which will assess niacin’s safety and immune system activation.

Niacin was found to restore function in weakened immune cells, improving their ability to target and destroy tumor cells. (iStock)

Dr. Marc Siegel, Fox News senior medical analyst, noted that previous research has shown that vitamin B3 decreases inflammation and bolsters immune function.

Advertisement

“Vitamins, including vitamin B vitamins (especially niacin), are underrecognized as immune boosters,” the doctor, who was not involved in the study, told Fox News Digital.

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Cautions and limitations

Despite the promising early results, the researchers urged caution.

“Glioblastoma is the most aggressive brain cancer in adults. Survival of patients with this condition hasn’t changed significantly for 20 years,” said lead study author Roldan Urgoiti, a clinical associate professor at the CSM, in the release. “Anything that may help should be explored, but it requires strict protocols and safety monitoring.”

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

Advertisement

The study’s small sample size, short follow-up and lack of a randomized control group also posed limitations, the researchers acknowledged.

The researchers cautioned that high doses of vitamins can pose health risks, and that usage should be monitored by doctors. (iStock)

Larger, controlled trials are needed to confirm the findings, they said.

The researchers also cautioned that high doses of vitamins can pose health risks, and that usage should be monitored by doctors.

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

Advertisement

Siegel agreed that niacin does have some side effects, including skin blushing.

“There probably will end up being a small impact here, so this is useful information, though clearly not a cure,” he added.

Advertisement

Health

Micro-Walking Plan for Weight Loss: Harvard Doctor Calls It a ‘Wonder Drug’

Published

on

Micro-Walking Plan for Weight Loss: Harvard Doctor Calls It a ‘Wonder Drug’


Advertisement





Micro-Walking Plan for Weight Loss That Burns Calories Fast




















Advertisement





Advertisement


Use left and right arrow keys to navigate between menu items.


Use escape to exit the menu.

Advertisement

Continue Reading

Health

Possible hantavirus case under investigation in upstate New York; no connection to deadly cruise ship outbreak

Published

on

Possible hantavirus case under investigation in upstate New York; no connection to deadly cruise ship outbreak

NEWYou can now listen to Fox News articles!

A “suspected” hantavirus case in upstate New York is being investigated, according to the Ontario County Public Health Department (OCPHD) based in Canandaigua.

The department announced in a Facebook post Thursday that it is currently “investigating a suspected locally acquired hantavirus case.”

“There is NO connection to the cruise ship outbreak, and there is no risk to the general public,” OCPHD officials wrote.

The investigation comes as global health officials continue monitoring a rare hantavirus outbreak tied to the MV Hondius luxury cruise ship that has sickened multiple passengers and crew members and left three people dead.

Advertisement

AMERICAN EVACUATED FROM CRUISE SHIP TESTS POSITIVE FOR HANTAVIRUS, ANOTHER HAS SYMPTOMS, HHS CONFIRMS

As of May 13, the World Health Organization (WHO) said 11 hantavirus cases had been identified in connection with the cruise outbreak, including eight confirmed cases, two probable cases and one inconclusive case. Three deaths have also been linked to the outbreak.

Health officials have emphasized that hantavirus infections remain rare and that the risk to the general public is low.

Human-to-human transmission of hantavirus is considered extremely rare and has only been suspected in certain strains, including the Andes hantavirus strain linked to the cruise ship outbreak.

HANTAVIRUS IN THE US: WHERE THE RARE, SOMETIMES DEADLY DISEASE HAS BEEN FOUND

Advertisement

A passenger wearing a face mask and blue protective gown gives a thumbs up inside a bus after disembarking from the hantavirus-stricken cruise ship MV Hondius at the port of Granadilla in Tenerife, Canary Islands, Spain, on May 10. (Manu Fernandez/AP Photo)

“Hantavirus infections are rare in New York,” the OCPHD said. “The virus is spread through mouse and rodent droppings, especially when urine, feces, or nesting materials become aerosolized during cleaning.”

The OCPHD urged residents to take precautions when cleaning enclosed spaces where rodents may be present, including wearing gloves and masks when opening or cleaning attics, cabins, sheds and garages.

The OCPHD and the Centers for Disease Control and Prevention (CDC) did not immediately respond to Fox News Digital’s request for comment.

REPORTED HANTAVIRUS PROTOCOL BREACH AT HOSPITAL FORCES 12 EMPLOYEES INTO 6-WEEK QUARANTINE

Advertisement

A 3D illustration shows the structure of hantavirus, an RNA virus transmitted to humans through rodent excreta that can cause severe illnesses including hemorrhagic fever, renal disease and hantavirus pulmonary syndrome. (iStock)

The cruise ship outbreak has prompted heightened precautions internationally.

In the Netherlands, Radboud University Medical Center quarantined 12 staff members after officials said a hantavirus patient’s blood and urine were not handled under the strictest international protocols required for the specific virus strain.

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

Hospital officials said the risk of infection to staff remained low but called the quarantine a precautionary measure.

Advertisement

The outbreak aboard the MV Hondius began after a Dutch cruise ship carrying 147 passengers and crew departed Argentina on April 1 for a South Atlantic voyage.

According to the WHO, investigators believe the initial infection may have stemmed from rodent exposure during birdwatching excursions before boarding the ship.

Fox News Digital’s Bonny Chu contributed to this report.

Continue Reading

Health

Cancer-related brain fog may improve with 2 simple treatments, scientists say

Published

on

Cancer-related brain fog may improve with 2 simple treatments, scientists say

NEWYou can now listen to Fox News articles!

A common over-the-counter medication combined with a home exercise program could help ease cognitive issues for cancer patients.

That’s according to a study from the University of Rochester, which tested the effects of physical activity and low-dose ibuprofen on patients receiving chemotherapy treatment.

“Chemo brain” (also called chemotherapy-related cognitive impairment, or CRCI) is a known side effect of cancer treatment that can affect memory, concentration and multitasking ability. Up to 80% of people who receive chemo experience some degree of cognitive impairment, previous studies have shown.

BRAIN AGING MAY ACCELERATE AFTER CANCER TREATMENT, STUDY SUGGESTS

Advertisement

Rochester’s phase 2 trial studied 86 adult cancer patients in New York undergoing chemotherapy who were experiencing cognitive problems. The average age was 53 and nearly 89% of participants were women, according to a university press release.

Participants who took only ibuprofen also showed greater cognitive improvements than the placebo group. (IStock)

Patients were randomly assigned to one of four groups. One group participated in home exercise designed specifically for cancer patients, a second group combined the exercises with ibuprofen (200 milligrams, or one pill, twice a day), the third group took ibuprofen alone and a fourth took a placebo alone.

TWO POPULAR TYPES OF EXERCISE COULD REDUCE CANCER GROWTH, STUDY FINDS

The exercise program consisted of low to moderate-intensity activity, including progressive walking and training with resistance bands.

Advertisement

“This is one of the first studies specifically designed to assess these interventions for cancer-related cognitive impairment during chemotherapy in patients with multiple diseases using both performance-based cognitive assessments and patient-reported outcomes,” said lead author Michelle C. Janelsins, Ph.D., MPH, of the University of Rochester and the Wilmot Cancer Institute, in the press release.

Up to 80% of people who receive chemo experience some degree of cognitive impairment.

After six weeks, exercise was linked to the clearest improvements in attention and cognitive function, according to input from family and friends. Those in the group who combined exercise and placebo showed better attention levels compared to those who took just a placebo.

CLICK HERE FOR MORE HEALTH STORIES

Participants who took only ibuprofen also showed greater cognitive improvements than the placebo group.

Advertisement

The findings suggest that ibuprofen may provide some improvement in cognitive function, although the benefits appeared to be smaller and less consistent than those seen with exercise.

“Chemo brain” (also called chemotherapy-related cognitive impairment, or CRCI) is a known side effect of cancer treatment that can affect memory, concentration and multitasking ability.  (iStock)

This suggests that inflammation may contribute to cancer-related cognitive impairment, and that anti-inflammatory medications could be an effective therapeutic approach.

“We are encouraged by the findings of this trial that suggest possible benefits of both interventions for some cognitive domains,” Janelsins said. “Clearly, we saw a more pronounced effect with exercise, which is notable considering the multiple health benefits of exercise for cancer survivors.”

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

Advertisement

No adverse side effects were reported during the trial.

The findings were published in Cancer, the peer-reviewed journal of the American Cancer Society.

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

There were some limitations of the study, the researchers noted, including the small sample size and short duration. The effects were also not consistent across every measure of cognitive function.

As the majority of participants were women, the findings may not be generalized to broader populations.

Advertisement

“Clearly, we saw a more pronounced effect with exercise, which is notable considering the multiple health benefits of exercise for cancer survivors,” the researcher said. (iStock)

Researchers are planning larger phase 3 trials to confirm whether ibuprofen and exercise can effectively improve chemo-related cognitive impairment.

“Since we saw cognitive benefits in some domains and not others, we will also consider additional doses and longer durations in future research trials,” said Janelsins.

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

Investigators emphasized that patients should speak with their oncology team before starting ibuprofen or exercise interventions during chemotherapy, as certain treatments or medical conditions could increase the risk of side effects and complications.

Advertisement

Continue Reading
Advertisement

Trending