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Next-generation fitness: New fields promise personalized exercise recommendations

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Next-generation fitness: New fields promise personalized exercise recommendations
Enduromics and resistomics are emerging disciplines that examine unique molecular adaptations to endurance and resistance training in a large population. Credit: Professor Katsuhiko Suzuki / Waseda University

Exercise has been recognized as an extremely effective tool to improve human health—it can have a preventative and even therapeutic effect on non-communicable diseases such as diabetes and cardiovascular diseases.

By promoting physical activity not only among athletes, but also among the general population, several non-communicable diseases can be prevented, eventually reducing the financial burden upon the health care system.

However, the exact changes that occur at a molecular level due to different types of exercise have not been explored thoroughly. One reason for this is that, traditionally, collecting molecular information (such as metabolite data) required invasive tissue or muscle biopsies, limiting the scale of studies that could be performed.

Now, in a study published in Sports Medicine—Open, Dr. Kayvan Khoramipour from Miguel de Cervantes European University, along with other co-authors, and Professor Katsuhiko Suzuki from the Faculty of Sport Sciences, Waseda University, Japan, introduce and review literature in two emerging fields that could advance our understanding of exercise physiology in humans.

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These disciplines use “multi-omics” data, or data from multiple sets of biological molecules (such as proteins, metabolites, or even RNA). Prof. Suzuki and his colleagues have termed these fields as “resistomics” and “enduromics.”

The authors explain that enduromics and resistomics are fields that examine the molecular changes induced by endurance and resistance training, respectively. While endurance training is what we might refer to as aerobic exercise (that increases your breathing and heart rate), resistance training involves improving your muscle strength.

To better explain these two terms, Prof. Suzuki further elaborates that, “Enduromics and resistomics examine unique molecular adaptations to endurance and resistance training in a larger population, as opposed to the field of ‘sportomics,’ which focuses on molecular alterations in competitive athletes.”

More specifically, enduromics reveals the biological pathways involved in processes such as lipid metabolism, generation of new mitochondria, and aerobic efficiency, or your body’s ability to effectively use oxygen—all of which adapt and change in response to moderate-to-intense aerobic exercise.

On the other hand, resistomics specifically focuses on muscle hypertrophy or muscle growth, synthesis of new proteins, and neuromuscular adaptations in the body. These fields can identify the biomarkers and metabolic fingerprints, aiding in understanding how specific metabolic states differ between individuals.

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Taken together, both resistomics and enduromics can give us a clear picture of the molecular adaptations that arise in different individuals in response to both resistance and endurance training.

Emphasizing the practical applications of enduromics and resistomics, Prof. Suzuki explains, “By utilizing molecular profiling, these disciplines pave the way for personalized exercise prescriptions, using molecular insights to tailor training to an individual.”

He adds that these personalized training plans can enhance fitness and rehabilitation while reducing injury risks for both athletes as well as the general population. The team also believes that by transitioning the focus from athletes to the general population, the collective health of society can be strengthened.

In the long term, Prof. Suzuki and his colleagues would like to discover molecular mechanisms underpinning adaptation to exercise, which could even prove helpful for disease prevention and treatment.

More information:
Kayvan Khoramipour et al, From Multi-omics To Personalized Training: The Rise of Enduromics and Resistomics, Sports Medicine – Open (2025). DOI: 10.1186/s40798-025-00855-4

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Why this unexpected exercise is most effective for building arm muscle in your 50s – and how to do it properly

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Why this unexpected exercise is most effective for building arm muscle in your 50s – and how to do it properly

When it comes to building strong, defined arms, traditional fitness advice will usually point you toward endless sets of bicep curls and tricep extensions. But according to Dr Stacy Sims, a leading women’s exercise physiologist specialising in perimenopause and menopause, isolation movements like these aren’t necessarily the most effective. Instead, she advocates for one functional compound movement: the farmer’s carry.

Speaking on podcast A Life of Greatness, when host Sarah Grynberg asks how to get arm muscles like Dr Sims, the 51-year-old explained: ‘In order to get shoulders like this, heavy farmer’s carries. I’ve been travelling so much this year, and I haven’t been in the gym being consistent with all the push presses and Olympic lifts that I love to do, but what I have been consistent in doing is heavy farmer’s carries.

‘It’s good for grip strength, learning how to walk properly, core strength, shoulders – so if there’s one move everyone should do, it’s heavy farmer’s carries.’

The magic of the move lies in its ability to engage your biceps, triceps, shoulders, forearms and hands all at once. And because your arms are working continuously to stabilise heavy loads against gravity, the exercise activates the deep muscle fibres that don’t fire up as efficiently in single-joint arm movements, like bicep curls. Here’s how to do it with proper form, plus how heavy to lift and a workout to try, straight from Dr Sims.

How to do a farmer’s carry

  1. Standing with feet hip-width apart and weights at the outside of the ankles, hinge your hips back and bend the knees, keeping your back flat.
  2. Tighten up your lower back and abdominals before reaching down to grab the weights.
  3. After gripping the weights, begin to stand tall by driving your heels into the ground, maintaining a tight form. Once you reach full standing position, tighten your armpits and make sure your shoulders are pulled back to activate the muscles in the rotator cuff area.
  4. Finally, begin to take small steps forward, maintaining a strong grip and form. If you’re returning in opposite direction, set the weights down, turn around, and then grab the weights again before walking in the opposite direction.

Set/reps for results: Aim for three sets. Try timing your farmer’s carry for 25 to 30 seconds or go for 10 steps forward and back.

Form tips: Start out with a light weight to ensure you don’t end up leaning too far forward or towards one side. Make sure to keep your back straight for safety. When it comes to moving, small strides will do. They’ll keep you balanced as you increase your weights.

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How heavy to lift

As for what “heavy” means to Dr Sims, she says: ‘How many people have heard that you should be able to farmer carry 75% of your body weight for a minute? That is made up from bro science. It’s a good metric but there’s no science behind it. So, a heavy farmer’s carry is you have two very heavy dumbbells by your side and you’re walking back and forth.’

Here’s a weight guide to follow:

  • Beginners: 2x 4-6kg
  • Intermediate: 2x 8-12kg
  • Advanced: 2x 12-20kg
Image no longer available

Farmer’s carry workout

Dr Sims shares a descending ladder workout to try.

  • 500m ski
  • 500m heavy farmer’s carry
  • 400m ski
  • 400m heavy farmer’s carry
  • 300m ski
  • 300m heavy farmer’s carry
  • 200m ski
  • 200m heavy farmer’s carry
  • 100m ski
  • 100m heavy farmer’s carry

‘If you really have anything left in the tank after this workout, you go back up in 100m,’ she adds.


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One of our most frequently asked questions here at Women’s Health? How to build muscle and burn fat at the same time. So, we asked superstar trainer Oyinda Okunowo exactly how to do it. In this 4-week plan – created exclusively for Women’s Health COLLECTIVE members – you’ll get the workouts and nutrition guidance needed to help you on your way to better body composition. Tap the link below to unlock 14 days of free access to Oyinda’s plan and start training today.

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As Women’s Health UK’s fitness director and a qualified Pilates and yoga instructor, Bridie Wilkins has been passionately reporting on exercise, health and nutrition since the start of her decade-long career in journalism.

After earning a first-class degree in journalism and NCTJ accreditation, she secured her first role at Look Magazine, where she launched the magazine’s health and fitness column, Look Fit, before going on to become Health and Fitness writer at HELLO!

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Since, she has written for Stylist, Glamour, Cosmopolitan, Marie Claire, Elle, The Metro, Runner’s World and Red. Today, she oversees all fitness content across Women’s Health online and in print, spearheading leading cross-platform franchises, such as ‘Fit At Any Age’, which showcases the women proving that age is no barrier to exercise.

She has also represented the brand on BBC Radio London, plus various podcasts and Substacks – all with the aim to encourage more women to exercise and show them how. Outside of work, find her trying the latest Pilates studio, testing her VO2 max for fun (TY, Oura), or posting workouts on Instagram.   

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When is the best time to exercise in the heat?

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When is the best time to exercise in the heat?

The sun is a welcome addition to our exercise routines come summer – but the novelty of a sunny run or hike can quickly wear off as the temperature climbs. With heatwaves and record-breaking temperatures already this year, it’s important to know the best time to exercise in the heat for the weeks ahead.

Obviously, if you don’t like the heat and would rather be inside, then you can exercise in an air-conditioned gym or studio at any time of day. A good swimming workout is another way to stay cool. However, if you enjoy running, hiking, cycling, or a garden strength training workout, it makes sense to choose the coolest times of day. In the peak of the summer, this is before 10 am and after 5 pm, but the earlier (or later) you can go, the better.

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Kylie Minogue, 58, shares how she stays fit without a strict exercise routine – ‘I don’t really work out’

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Kylie Minogue, 58, shares how she stays fit without a strict exercise routine – ‘I don’t really work out’

Kylie Minogue has stayed active her whole life, but, refreshingly, she doesn’t follow a punishingly strict routine to stay fit.

‘I wish I was one of those women who do their exercises first thing in the morning, or run straight to the fitness studio as soon as they get up,’ she told Star Magazine. ‘But unfortunately, I’m just not that disciplined!’

Instead, the ‘I Should Be So Lucky’ singer partly relies on her hectic schedue to keep her moving. ‘I don’t really work out, but I’m constantly on the go,’ she told Express.

‘My guilty confession is that there isn’t [a routine]!…I think I stay in shape with an active (read, exhausting!) lifestyle,’ she continued on Reddit. ‘My fitness is really sporadic. I have to thank my mum for good genes.’

Kylie Minogue’s go-to exercises

Despite her self-professed low-key approach, the global multi-platinum recording artist incorporates several workout methods into her day, preferring mainly low-impact and moderate-intensity exercise.

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‘I do Pilates,’ she continued to Star. But she’s careful to keep things balanced. ‘I don’t overdo it,’ she clarified.

‘I like to at the very least do 15 minutes on the Yoga Studio app. I know how to do it without the app but the tone of the woman’s voice and that it’s timed, it goes by so quickly,’ she told WSJ. ‘Then I feel like that’s done and I feel good.’

Often, her exercise of choice also depends on what equipment is available.

‘If there’s a treadmill nearby, I like to do that. We say in my family, “Minogues don’t run.” None of us run. But we like to walk, so that works for me,’ she added. ‘If I’m somewhere where there’s Pilates, I love that.’

Workouts that provide holistic physical and mental benefits are often a favourite.

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‘I’ve also tried Gyrotonics; that was really fun,’ she continued, referring to the gymnastics-and-swimming-inspired movement system developed by Julia Horvath in the 80s. Designed to decompress the body, build strength and flexibility, and improve posture, it’s increasingly being adopted by Olympic athletes and celebrities alike.

‘I loved aerobics and I used to do Callanetics,’ she added to Express. Created by classical ballet-trained Callan Pinckney around 40 years ago, Callanetics uses ‘small, precise pulsing movements’ to ‘activate muscles’. I would travel everywhere with this home workout on a VHS tape and put it on in hotel rooms,’ Kylie revealed.

However, being the ‘Princess of Pop’ does mean that the physical demands are considerable, and often her endurance, coordination and overall fitness are put to the test when she’s on stage.

‘I would say my ultimate workout is being on tour. I’m never as fit as when I’m on tour, so I can’t wait to tour again. My body needs it.’


One of our most frequently asked questions here at Women’s Health? How to build muscle and burn fat at the same time. So, we asked superstar trainer Oyinda Okunowo exactly how to do it. In this 4-week plan – created exclusively for Women’s Health COLLECTIVE members – you’ll get the workouts and nutrition guidance needed to help you on your way to better body composition. Tap the link below to unlock 14 days of free access to Oyinda’s plan and start training today.

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Get the plan


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