Fitness
Mitochondria and aging: Why HIIT is the game-changer for fitness and longevity
The mitochondria are considered the ‘powerhouses’ or ‘engines’ of your cells. As Dr. Terry Wahls points out, most chronic diseases involve dysfunctional mitochondria. Poorly functioning mitochondria play a big role in disease risks, a slower metabolism, and the aging process. Researchers have concluded that exercise improves mitochondrial quality and function and stimulates mitochondrial turnover. It’s time to start thinking about these little organelles that have a big impact on our wellness and longevity.
Exercise for your mitochondria
Additional research also revealed that just 12 weeks of resistance exercise training yielded qualitative and quantitative changes in skeletal muscle mitochondrial respiration. Not only did resistance training increase lean body mass by 4% and quadriceps muscle strength by 15%, but staying committed to those 12 weeks of training also improved the respiratory capacity and functioning of the mitochondria.
So, which exercise is superior for improving mitochondrial functioning? Which exercise results in the most dramatic positive cellular changes? Let’s dive into the research.
The study

In a study published in Cell Metabolism, the researchers explored how different types of exercise — resistance training, high-intensity interval training (HIIT), or a mix of both — change muscles and cells at the molecular level in younger and older adults. The researchers focused on how genes and proteins respond to exercise, how exercise impacts the mitochondria, and how these changes affect overall fitness and metabolism.
The study methods
For 12 weeks, younger and older adults completed one of three exercise programs: traditional resistance training, HIIT, or a mix of both at a lower intensity. The researchers measured fitness and VO2 peak, insulin sensitivity, muscle mass and strength, mitochondrial health and function, and changes in gene activity and protein levels in muscle.
The results
Here are the study results:
- HIIT has the biggest impact in improving aerobic fitness, insulin sensitivity, and mitochondrial function, compared to other workouts. These results were especially noticeable for older adults.
- HIIT reversed some age-related declines in muscle mitochondria and enhanced the cell’s ability to make new proteins.
- HIIT enhanced mitochondrial capacity by close to 50% for young adults and nearly 70% in older adults.
- Resistance training mostly helped build muscle mass and strength, but didn’t have as much of an impact on aerobic fitness or mitochondria. The combined training resulted in smaller and moderate benefits compared to just doing HIIT alone.
Changes at the molecular level
HIIT caused significant increases in gene activity and protein-building machinery. Most of the benefits from exercise take place after the genes send their signals during the protein-building stage. HIIT improved protein quality and helped reduce damage to muscle proteins, which helps the body build new and efficient mitochondria.
Concluding thoughts

This study shows that HIIT is one of the most powerful ways to improve muscle health and fitness even in later years. This type of exercise, which involves shorter bursts or intervals of higher-intensity movements, is superior for the mitochondria and helps your body make more and better mitochondria, which can slow age-related decline and boost your energy levels.
Fitness
How much exercise should you do to protect your heart | The Jerusalem Post
Physical activity saves lives, but now it turns out there’s a “precise dosage” at which it becomes especially effective in preventing heart disease.
Fitness
A Doctor Says This Is the Number-1 Exercise Women Over 50 Should Add to Their Routine
Exercising is key to longevity; it’s been associated with everything from improved cardiovascular health to increased strength to a longer life. But there’s one exercise, in particular, that a doctor says women over 50 should add to their routine.
Meet the expert: Steven Bowers, D.O., board-certified family physician and author of Secrets of the World’s Healthiest People
Daily strength workouts may help boost all aspects of life, Steven Bowers, D.O., board-certified family physician and author of Secrets of the World’s Healthiest People, previously told Prevention. Physical fitness makes functional tasks like carrying grocery bags from the car, opening jars, and lifting heavy items easier.
There are plenty of moves to try, but Dr. Bowers says the one that should get top billing in your routine is the plank.
While planks challenge your whole body, they’re particularly great for strengthening your core. “Core muscle fibers tend to shrink and become less supple as we age, which can put more strain on your back,” he previously said. Having a strong core is important for balance and stability, and it can help you go about your day with more ease.
Wondering how long to hold a plank, and the proper form? First, place your forearms on the floor. Your elbows should be right below your shoulders, and your arms should be parallel—not turning in or out. Your feet should also be shoulder-width apart. Press your hands and toes into a mat on the ground, lifting your body, squeezing your glutes and quads for support. Your body should create one straight line from head to toe. Don’t lock your knees or arch your back, and keep your neck straight by looking slightly in front of you.
Hold this position for 20 seconds. “As you get more comfortable and your core gets stronger, hold the plank for as long as possible without sacrificing form or breath,” Dr. Bowers noted. It’s that simple! Whether you’re a pro or want to test your plank skills, adding the simple move to your routine may be what your core has been waiting for.
Fitness
Dull ache in your shin when running? Try these five osteopath-approved exercises
Shin splints are one of those nagging aches and pains most runners encounter at some point in their training—but that doesn’t mean you should just grin and bear it.
“We see it all the time in the clinic,” osteopath and clinical lead at The Livewell Clinic, Danny Sayandan tells Fit&Well.
Common themes, he says, are runners in worn-out shoes, heel striking instead of landing midfoot, or overstriding.
“It’s often linked to the least stretched muscle in the body—your calves—and most neglected muscle—the tibialis anterior—found on the front of the shin,” says Sayandan.
When they’re tight or undertrained, the impact of every footstrike gets pushed straight into the shins, triggering a dull ache down the front or inside of your shins.
The solution? Add these five exercises from Sayandan to your weekly workouts to stretch and strengthen these often overlooked muscles.
5 exercises to try if you get shin pain when running
1. Toe raise
Watch On
Sets: 2 Reps: 12-15 each side
Why: Lifting your toes strengthens the front of your shin.
How:
- Stand with your feet hip-width apart.
- Lift your toes.
- Hold for two seconds.
- Lower your toes to the start.
2. Calf raise
Sets: 2 Reps: 12-15
Why: Build strength and endurance in the lower legs.
How:
- Stand with your feet together.
- Lift your heels to rise onto your toes and the balls of your feet.
- Pause, then lower slowly.
You can also perform these with your heels off a step (as in the video above), lowering your heels below the step to add a stretch to your calves.
As you get stronger, progress to single-leg calf raises, then begin to add weight with a dumbbell or kettlebell held in one hand.
3. Soleus wall hold
Sets: 2 Reps: 12-15 / Time: 30sec
Why: This bent-knee heel raise targets the deep-lying soleus muscle in your calves.
How:
- Stand with your feet hip-width apart, holding a bannister or other sturdy anchor point for support (an alternative is to rest your back on a wall, as in the video above).
- Bend your knees and push your hips back to lower into a squat, with your knees bent at 90˚.
- Hold this position and either perform 12-15 calf raises (see above), or rise up onto the balls of your feet and hold for 30 seconds.
4. Tibialis stretch
Watch On
Sets: 2 Reps: 8-10
Why: This is a gentle stretch for the muscles in the front of the shin.
How:
- Kneel with your feet together, sitting on your heels with your hands or forearms on the floor to help control the load through your ankles.
- Push through your hands or forearms and carefully lift your knees to increase the stretch in the front of your shins.
- Hold for a few seconds, then lower.
Rather than an exercise, try to practice this continuously—and certainly as you move from exercise to exercise in this workout. Concentrate on landing softly through your midfoot to retrain your gait and reduce impact through your heel, ankle, calves and shins.
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