Health
Americans born after 1970 face higher death rates from several major causes in middle age
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Americans born after 1970 are dying faster than their parents did, data shows.
New analysis from Tufts University reveals that Gen Xers and millennials are failing to outlive their predecessors, dying at higher rates from common chronic illnesses and external causes than previous generations did when they were the same age.
Data shows that U.S. life expectancy has steadily improved for most of the 20th century, meaning each generation generally lived longer than the one before it.
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However, that changed starting with individuals born in the 1950s. While Americans born in the 1940s experienced steadily improving survival rates at every stage of life, those born in the 1950s saw that progress slow or reverse.
The downward trend has continued with each subsequent generation, with the biggest change seen in Americans born after 1970.
While Americans born in the 1940s experienced steadily improving survival rates at every stage of life, those born in the 1950s saw that progress slow or reverse. (iStock)
The research, which tracks 45 years of American mortality data from 1979 to 2019, was published in the Proceedings of the National Academy of Sciences, according to a Tufts press release.
Between the ages of 30 and 49, Americans born after 1970 experience higher death rates from heart disease, cancer and external causes (such as drug overdoses, suicide, homicides and traffic accidents) compared to older generations when they were in that same age bracket.
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Why are younger generations dying sooner?
Because the study focused on mapping patterns rather than conducting clinical trials, researchers say it can’t point to a single definitive cause for the decline.
However, the study points out two distinct issues affecting American life expectancy. The first is generational decline, meaning that newer generations are entering middle age while carrying higher risk factors than their predecessors.
Part of the decline is marked by a slowdown of decades-long progress against cardiovascular disease. (iStock)
Additionally, a separate, nationwide setback began around 2010, negatively impacting almost every living adult simultaneously, regardless of their birth year. Researchers say this period was marked by a slowdown of decades-long progress against cardiovascular disease.
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U.S. life expectancy improved by just 0.26 years between 2010 and 2019. In comparison, the country gained an average of 1.78 years of life expectancy per decade over the previous 50 years, according to the analysis.
This has caused the U.S. to fall further behind on a global scale. The life expectancy gap between the U.S. and the top-performing nation grew from 2.6 years in 1983 to 4.7 years by 2009.
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Shifting health risks
Earlier generations were heavily impacted by cigarette smoking. In contrast, younger generations face rising obesity rates and related conditions, such as colon cancer, data shows.
Because Americans born after 1970 are still in the middle stages of life, the full impact of these elevated mortality rates has not yet fully registered in overall national life expectancy figures. (iStock)
The researchers noted that the rise of the opioid epidemic also significantly accelerated overdose deaths for post-1970 generations starting in the late 1990s.
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The team cited widening economic inequality, social instability and chronic stress as larger issues that could be driving multiple causes of death at the same time.
Because Americans born after 1970 are still in the middle stages of life, the full impact of these elevated mortality rates has not yet fully registered in overall national life expectancy figures, they noted.
Looking ahead, the researchers plan to analyze newly released 2024 mortality data to understand how the pandemic may have affected U.S. mortality trends. (iStock)
“Although this study does not provide direct evidence, we can speculate about some interventions to explore,” lead study author Leah Abrams, an assistant professor of community health at Tufts University, said in the press release.
“To reduce deaths from cardiovascular disease, we may want to address risk factors such as diabetes, hypertension and obesity. Addressing colon cancer mortality among younger individuals may involve related factors and benefit from improving diet.”
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Looking ahead, the researchers plan to analyze newly released 2024 mortality data to understand how the pandemic may have affected U.S. mortality trends.
Health
Flying with cannabis? TSA’s new guidance comes with a major health warning
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The Transportation Security Administration (TSA) recently updated its medical marijuana guidelines, adding specific instructions to its “What Can I Bring?” directory for both carry-on and checked bags.
Patients who use cannabis to manage chronic pain, anxiety, nausea or other qualifying conditions may travel with their medication for use at their destination.
When taking medical marijuana on a flight, experts suggest separating the travel process from the treatment and waiting until arriving at the destination before using the substance.
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“For most patients, the goal isn’t to use cannabis on the plane. It’s making sure they have access to their medicine when they arrive,” Professor Rob Mejia of the Stockton University Cannabis Studies Department, who is also author of “The Essential Cannabis Book,” told Fox News Digital.
Patients who use cannabis to manage chronic pain, anxiety, nausea or other qualifying conditions may travel with their medication for use at their destination. (iStock)
Using cannabis on aircraft is generally not recommended. Airlines strictly prohibit smoking and vaping, and even edible products can behave unpredictably.
While some experienced consumers may use a low-dose edible before a flight to manage flight anxiety or promote sleep, Mejia said the key factor is familiarity.
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“An airport or airplane is not the place to test a new product or take a dose you are not accustomed to,” he advised. “What feels relaxing to an experienced consumer can easily feel overwhelming to someone with less experience.”
According to clinical data published by the American College of Cardiology, cannabis use significantly alters heart rhythm regulation and heightens the heart muscle’s overall oxygen demand.
“An airport or airplane is not the place to test a new product or take a dose you are not accustomed to.”
When this elevated cardiac strain combines with the nervous system’s natural response to altitude — which, according to University of Florida research, already forces the heart to beat faster to distribute lower levels of oxygen — it can trigger acute cardiovascular distress.
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Rather than relieving travel anxiety, using unpredictable or high-potency doses at high altitudes can worsen symptoms like severe nausea, dizziness and hyperventilation, research shows.
Previous data shows cannabis can alter heart rhythm and oxygen demand, which may not be ideal with cabin altitude. (iStock)
“The overall goal should be continuity of care during travel, not medicating at 35,000 feet,” Mejia said.
For a growing number of patients, cannabis is no longer just an alternative therapy, but functions as a primary form of medicine. In these cases, before traveling with the substance, preparation is everything, experts say.
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“The safest cannabis travel plan is understanding the laws before you pack,” Mejia advised, warning travelers not to misinterpret the updated language.
Using unpredictable or high-potency doses at high altitudes can backfire, leading to severe nausea, dizziness and hyperventilation rather than relieving travel anxiety, experts caution. (iStock)
“A TSA checkpoint is not a legal shield from state or local enforcement,” the expert noted. “The TSA checks for security threats, not cannabis. That doesn’t mean cannabis can’t become your problem.”
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“If your cannabis looks legitimate, labeled and professionally packaged, you’re less likely to raise questions.”
“If your cannabis looks legitimate, labeled and professionally packaged, you’re less likely to raise questions than if you’re carrying a bag of mystery gummies and a handful of loose flower,” Mejia added.
“The TSA checks for security threats, not cannabis. That doesn’t mean cannabis can’t become your problem.” (iStock)
If an item raises eyebrows, the agent has the authority to refer the matter to law enforcement.
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While domestic travel has entered a gray area, international travel remains a different set of rules altogether. Crossing international borders with cannabis carries severe risks, regardless of the laws of the country you are visiting, experts say.
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“If you’re traveling internationally, leave your cannabis at home,” Mejia advised. “Even in countries that have legalized cannabis, the rules for visitors can be very different from the rules for residents.”
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Health
Diabetes drug could slash risk of fatal heart condition in one group, scientists reveal
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A diabetes drug could help lower the risk of heart failure in certain patients.
A new study published in Nature Medicine analyzed how SGLT2 inhibitor dapagliflozin, a medication used to treat type 2 diabetes, could help prevent heart failure in people with rare genetic variants linked to cardiomyopathy (a progressive disease of the heart muscle).
Using data from the DECLARE-TIMI 58 trial, researchers from Harvard Medical School, Mass General Brigham and MIT looked at more than 12,000 adults who had type 2 diabetes and increased cardiovascular risk.
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About 121 participants carried inherited gene variants that could raise their chances of developing cardiomyopathy.
After a median 4.2-year follow-up, dapagliflozin was found to lower hospitalization for heart failure more in individuals with the variants than in those without.
Dapagliflozin was found to lower hospitalization for heart failure in individuals with the variants for cardiomyopathy more than those without them. (iStock)
While dapagliflozin lowered heart failure hospitalization in both groups, the reduction was about eight times stronger in carriers of the genetic variant.
Among the 82% of carriers without a prior history of heart failure, 12.8% developed heart failure in the placebo group, while no heart-failure events were observed among carriers receiving dapagliflozin.
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Co-lead study author Shinwan Kany, MD, a visiting scientist at the Cardiovascular Research Center with Mass General Brigham Heart and Vascular Institute and the Broad Institute, commented on how these findings could shape preventive care.
“Historically, identifying a genetic variant for cardiomyopathy mostly meant telling a patient they were at high risk and not having a specific preventive therapy to offer,” he said in a press release. “These data show we do have tools to lower risk in these individuals.”
In the placebo group, carriers had about eight times higher risk of hospitalization compared to non-carriers. (iStock)
As this was an analysis of a larger randomized trial, the results require further confirmation, according to experts. The narrow sample size of carriers also poses a limitation.
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“These findings are very encouraging because they suggest we may be entering an era where heart failure prevention becomes more precise and more genetically informed,” Andrew Freeman, MD, a cardiologist at National Jewish Health, told Fox News Digital.
Freeman, who was not involved in the study, called the research “important and provocative.”
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Participants with no history of heart failure who took dapagliflozin were less likely to develop the condition, a finding that “raises the possibility that SGLT2 inhibitors may be especially useful as preventive therapy in genetically high-risk individuals,” the doctor said.
Dapagliflozin is a prescription medication used to manage type 2 diabetes, heart failure and chronic kidney disease. (iStock)
“This should be viewed as an exciting hypothesis-generating finding, not yet a practice-changing mandate for all patients with these genetic variants,” Freeman cautioned.
SGLT2 inhibitors are already “foundational” cardiovascular and kidney-protective medications, the doctor noted.
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“They reduce heart failure hospitalization across a broad range of patients, including those with diabetes, chronic kidney disease and established heart failure,” he said. “What this study adds is the possibility that genetic information may help identify a subgroup of people who derive especially large benefit from early treatment.”
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Genetic testing for cardiomyopathy is often used for diagnosis, family screening and risk stratification, Freeman said.
If future clinical trials confirm the findings, cardiologists could eventually use genetic screening to identify high-risk patients, monitor them more closely, and begin treatments such as SGLT2 inhibitors before heart failure symptoms appear, according to the cardiologist.
Genetic testing for cardiomyopathy is often used for diagnosis, family screening and risk stratification. (iStock)
Heart failure does not always begin when symptoms appear, Freeman noted. In some patients, risk may be present years earlier due to inherited genetics.
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Preventive cardiology could identify high-risk patients earlier, before they develop symptoms such as shortness of breath, fluid retention or the need for hospitalization.
The decision to medicate should always be discussed with a clinician, Freeman advised, especially for those with a personal or family history of cardiovascular events.
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