Health
Aggressive brain cancer may respond to high-dose vitamin therapy, study suggests
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High-dose vitamin B3 (niacin) may enhance immune activity and improve short-term disease control in glioblastoma when added to standard therapy, according to early preclinical studies.
Glioblastoma is a highly aggressive, fast-growing brain cancer that develops from cells in the brain and spinal cord.
In previous laboratory experiments in mice, niacin was shown to extend survival. Researchers at the University of Calgary aimed to determine whether that same benefit extended to humans.
COMMON BLOOD PRESSURE PILL COULD MAKE CERTAIN CANCER TREATMENTS MORE POWERFUL
The trials included 24 patients with glioblastoma, which has a median survival of roughly 12 to 18 months.
Six months after receiving niacin in addition to standard treatments (surgery, radiation and chemotherapy), 82% of the patients showed no disease progression, compared to the typical 54%, according to the study’s press release.
Left to right: Edward (Ed) Waldner (study participant), Dr. Wee Yong, PhD, (scientist), Dr. Gloria Roldan Urgoiti, MD, (oncologist) (Riley Brandt, University of Calgary)
Niacin was also found to restore function in weakened immune cells, improving their ability to target and destroy tumor cells.
The findings, including the 28% improvement in disease progression, were published in the Journal of Neuro-Oncology.
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“Normally, the immune system will try to counter and prevent tumor growth; however, this brain cancer suppresses the immune system,” said study author Dr. Wee Yong, PhD, a neuroscientist who studies immune responses in the brain, in the release. “Niacin treatment rejuvenates immune cells so they can do what they are supposed to do: attack and kill the cancer cells. I see it as an ongoing ‘battle for the brain.’”
Looking ahead, the team plans to enroll an additional 24 patients by the end of 2026 or early 2027 for the next phase of the trial, which will assess niacin’s safety and immune system activation.
Niacin was found to restore function in weakened immune cells, improving their ability to target and destroy tumor cells. (iStock)
Dr. Marc Siegel, Fox News senior medical analyst, noted that previous research has shown that vitamin B3 decreases inflammation and bolsters immune function.
“Vitamins, including vitamin B vitamins (especially niacin), are underrecognized as immune boosters,” the doctor, who was not involved in the study, told Fox News Digital.
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Cautions and limitations
Despite the promising early results, the researchers urged caution.
“Glioblastoma is the most aggressive brain cancer in adults. Survival of patients with this condition hasn’t changed significantly for 20 years,” said lead study author Roldan Urgoiti, a clinical associate professor at the CSM, in the release. “Anything that may help should be explored, but it requires strict protocols and safety monitoring.”
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The study’s small sample size, short follow-up and lack of a randomized control group also posed limitations, the researchers acknowledged.
The researchers cautioned that high doses of vitamins can pose health risks, and that usage should be monitored by doctors. (iStock)
Larger, controlled trials are needed to confirm the findings, they said.
The researchers also cautioned that high doses of vitamins can pose health risks, and that usage should be monitored by doctors.
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Siegel agreed that niacin does have some side effects, including skin blushing.
“There probably will end up being a small impact here, so this is useful information, though clearly not a cure,” he added.
Health
LeAnn Rimes’ emotional reaction to jaw release therapy sparks widespread buzz
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Singer LeAnn Rimes has gone viral for her reaction while receiving jaw release therapy.
In a session with Garry Lineham, co-founder of Human Garage in California — a resource for self-healing practices — Rimes received an intra-oral massage, releasing the tension in her jaw. She seemed to instantly feel relief, sobbing on the table.
Jaw release therapy, which involves the massaging or stretching of muscles in the face, is popular for relieving TMJ pain, headaches and jaw clicking, according to experts.
LEANN RIMES BREAKS DOWN INTO TEARS WHILE UNDERGOING ‘DEEP JAW RELEASE’
In an interview with Fox News Digital, Lineham shared that stress has an immense impact on human health, especially on muscle tension and pain.
“We hold emotions in our body,” he said. “Emotions cause a sympathetic response or a stress response in the body.”
“When you release the jaw, instantaneously you come out of that fight or flight mode,” Lineham said. (iStock)
“Stress is one thing that impacts every disease, whether it’s emotional or physical, whether it is genetic,” he went on. “Stress is the thing that makes genetics pop. If you take away stress, those genetic markers no longer express themselves.”
STUDY REVEAL WHY CHEWING GUM MIGHT ACTUALLY HELP WITH FOCUS AND STRESS RELIEF
Clenching the jaw can create stress, which happens naturally with physical and emotional exertion, according to Lineham.
“If you clench your jaw and hold it there for three to five minutes … you’ll actually fire adrenaline and norepinephrine (hormones and neurotransmitters),” he said.
This sends a message to the body that you’re bracing for an “attack,” releasing hormones like stress, Lineham added.
“When you release the jaw, then instantaneously you come out of fight or flight mode.”
How jaw release works
Jaw release therapy targets the fascia, or the connective tissue that supports the body’s muscles, organs and joints. Stretching the fascia also allows the muscle to stretch, providing relief, Lineham said.
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“When you release the jaw, then instantaneously you come out of that fight or flight mode,” he said. “And if you’ve been there for a long time, like most people have, it instantaneously shocks the nervous system in a good way.”
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Dr. Justin Richer, oral and maxillofacial surgeon at Riverside Oral Surgery in New Jersey, shared the benefits and risks of jaw release treatment with Fox News Digital.
Jaw release therapy can help with facial pain and muscle tightness. (iStock)
Certain muscles in the body, such as the shoulder or back, can tense up and “overreact to problems that are going on within them,” said the doctor, who did not treat Rimes.
“Jaw release is almost like a massage or similar technique, to put pressure on the muscles and let the tension that’s built up just kind of relax away,” he said. “It’s not something that a lot of people do.”
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The procedure is most beneficial for those with symptoms of TMJ, facial and muscle pain, and tightness, according to Richer.
Some physical therapists and massage therapists offer this treatment, but Richer recommends seeking help from an oral-facial pain specialist or surgeon who “really understands the anatomy of the jaw joint.”
Dr. Richer recommends seeing an oral surgeon or specialist before seeking the procedure. (iStock)
“If it’s done properly, there’s very minimal risk,” he said. “What we get concerned about is undue manipulation of the joint, so either cracking or distorting or trying to forcefully move the joint . . . that can actually cause undue harm from an orthopedic perspective.”
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Despite the benefits, Richer stressed that this kind of therapy may be a temporary fix, as it could be treating only the symptoms of an underlying problem.
“Get a diagnosis first before you go ahead and start manipulating things,” he advised.
Health
Study reveals one simple eating habit that may help boost weight loss
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Losing weight might be as simple as sticking to the meals you know, a new study found.
People who ate the same meals more often lost more weight during a 12-week weight-loss program, according to a new study published in Health Psychology.
“Maintaining a healthy diet in today’s food environment requires constant effort and self-control,” lead author Charlotte Hagerman of the Oregon Research Institute said in a statement.
SIMPLE WEIGHT-LOSS QUIZ MAY PINPOINT WHY SOME DIETS FAIL — AND HOW TO BOOST SUCCESS
“Creating routines around eating may reduce that burden and make healthy choices feel more automatic.”
Experts say maintaining muscle after 50 may require more protein than the minimum federal guideline. (iStock)
Hagerman and fellow researchers from Drexel University and the Oregon Research Institute analyzed food logs from 112 adults who were overweight or obese who tracked their meals in an app and weighed themselves daily, according to the study.
The researchers measured “routinized” eating in two main ways —how much participants’ daily calorie intake fluctuated and how often they repeated the same meals and snacks over time, according to the paper.
DOCTOR WARNS MANY AMERICANS EAT ‘FOOD-LIKE SUBSTANCES,’ NOT REAL FOOD
Those whose diets included more repeated foods lost an average of 5.9% of their body weight compared to 4.3% for those whose eating patterns were more varied, according to a press release from the American Psychological Association.
A man shows how much weight he has lost by holding out the waist of his jeans, symbolizing his successful diet. (iStock)
People who kept their daily calorie intake more consistent also lost more weight, according to the researchers.
Liza Baker, a Vermont-based nutrition expert and founder of Simply: Health Coaching, said the findings line up with what she has seen firsthand in more than a decade of working with clients.
“Removing the mental load of ‘What’s for breakfast, lunch or dinner?’ can make the wellness journey much more sustainable,” Baker told Fox News Digital.
A breakfast of oatmeal porridge with summer berries. (iStock)
She said repeat meals can reduce decision fatigue and make it easier for people to stick to healthier habits, especially when they are packing lunches, cooking at home and following a simple routine.
Baker said people do not necessarily have to repeat every meal to see benefits.
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“One can start by eating one meal that is repetitive, usually breakfast or lunch,” she said. “As results start to show, it’s then more conducive to increasing to two to three repetitive meals a day.”
At the same time, experts cautioned that the findings do not prove cause and effect. The study was observational, meaning it found an association between routine eating and greater weight loss but could not show that repetition alone caused the better results, according to the researchers.
Consistency — not variety — may be key when it comes to weight loss, researchers found. (iStock)
Baker also warned that repeat meal plans can backfire if they are not nutritionally balanced or if they trigger perfectionism.
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“Unless someone is well-versed in nutrition, setting up a repeat meal plan can quickly become a nutritional nightmare that leads to becoming deficient in one or more nutrients,” she said.
The study authors similarly noted that too little variety could come with trade-offs. Future research is needed to determine whether a more repetitive diet should be actively recommended as a weight-loss strategy, they said.
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Fox News Digital reached out to the study’s authors for comment.
Health
Prayer for Weight Loss Works: How Faith Can Help You Shed Weight Faster
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