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Actor Eric Dane’s death from ALS sparks urgent focus on rapid decline

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Actor Eric Dane’s death from ALS sparks urgent focus on rapid decline

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Eric Dane’s death has sparked conversations about the speed and severity of ALS.

Also known as Lou Gehrig’s disease, the progressive illness — officially called amyotrophic lateral sclerosis — is debilitating and fatal. 

While only about 5,000 people in the U.S. are diagnosed each year, the average life expectancy is just two to five years, according to the ALS Association.

Dane, who most famously starred as Dr. Mark “McSteamy” Sloan on ABC’s “Grey’s Anatomy,” announced his diagnosis in April 2025, telling “Good Morning America” in June that his first symptoms began as “some weakness” in his right hand.

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‘GREY’S ANATOMY’ STAR ERIC DANE DEAD AT 53

“I didn’t really think anything of it,” the actor said. “At the time, I thought maybe I’d been texting too much, or my hand was fatigued. But a few weeks later, I noticed that it got a little worse.”

“I’m fighting as much as I can,” Dane added. “There’s so much about it that’s out of my control.”

Eric Dane starred as Dr. Mark “McSteamy” Sloan on “Grey’s Anatomy” for seven seasons. (Bob D’Amico/Disney General Entertainment Content via Getty Images)

What is ALS?

ALS is a progressive disease where the brain loses connection with the muscles, according to the ALS Association. This slowly strips a person’s ability to walk, talk, eat, dress, write, speak, swallow and, eventually, breathe.

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Early signs include muscle weakness, stiffness and cramping. Symptom progression and severity are different for each case, as the association notes there is “no single timeline for ALS.”

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The disease only impacts motor neurons controlling voluntary movement, so the five senses — sight, touch, hearing, taste and smell — are not affected, nor are the eye muscles or bladder control.

ALS symptoms typically begin with muscle weakness in the upper extremities. (iStock)

Many ALS patients remain “mentally alert and aware” throughout the disease, the ALS Association reported.

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Diagnosis typically occurs in people between the ages of 40 and 70. About 20% of patients live five years or longer. Only about 5% live longer than 20 years.

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ALS is typically diagnosed by a neurologist with an electromyography test (EMG), but can also be detected by blood and urine tests, spinal taps, MRIs and other imaging scans, muscle and nerve biopsies, or neurological exams.

There is currently no cure or treatment to stop disease progression, although there are treatments to slow and ease symptoms, per the ALS Association.

ALS can be diagnosed by a neurologist through various forms of testing. (iStock)

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Fox News senior medical analyst Dr. Marc Siegel joined “Fox & Friends” on Friday to discuss the prevalence of ALS, suggesting that cases have increased due to “something in the environment that we don’t know yet.”

While ALS is 10% genetic, according to Siegel, 90% of cases do not have a genetic link, pointing toward other risk factors like environmental toxins.

“We’re learning to personalize the approach to this disease.”

“It’s a muscle weakness disease — affecting nerves that innervate muscles — and usually it starts on one side,” the doctor shared. “Then you develop fatigue … You could see a quivering tongue or your arm is quivering, usually one side and then the other side.”

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As the weakness progresses, it impacts speech and ultimately attacks the diaphragm, making it difficult to fully inflate the lungs.

“That’s what happened to [Dane], most likely,” Siegel said. “So, it progresses from your arms, your legs, your speech, your swallowing ability and then your breathing.”

Rising research

ALS progresses “pretty rapidly in most cases,” Siegel said. While scientist Stephen Hawking lived 55 years with the disease, Dane “probably lived about two years with it,” the doctor surmised.

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“I want to point out how courageous [Dane] is — he actually was involved with Target ALS, where he was fighting for new research,” Siegel pointed out. “We’re learning to personalize the approach to this disease, and that’s the future — and he fought for that.”

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Actor Eric Dane is photographed at the St. Regis in Washington, D.C., on Sept. 30, 2025. “I want to point out how courageous [Dane],” said Dr. Marc Siegel. (Marvin Joseph/The Washington Post via Getty Images)

“We need a lot of money for research for this — [Dane] was asking for a billion dollars from the government.”

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Various research groups and hospital systems are actively working on new ALS therapies that take a personalized approach, Siegel shared.

The estimated cost to develop a drug that would slow or stop disease progression is $2 billion, the ALS Association has reported. The annual estimated out-of-picket cost for care is $250,000.

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Funding for ALS research and awareness has been on the rise for years, with the viral social media ALS Ice Bucket Challenge making a splash in 2014. 

The challenge, supported by the ALS Association, was intended to boost awareness. It ultimately raised $115 million toward ALS research and patient care.

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Heart disease threat projected to climb sharply for key demographic

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Heart disease threat projected to climb sharply for key demographic

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A new report by the American Heart Association (AHA) included some troubling predictions for the future of women’s health.

The forecast, published in the journal Circulation on Wednesday, projected increases in various comorbidities in American females by 2050.

More than 59% of women were predicted to have high blood pressure, up from less than 49% currently.

The review also projected that more than 25% of women will have diabetes, compared to about 15% today, and more than 61% will have obesity, compared to 44% currently.

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As a result of these risk factors, the prevalence of cardiovascular disease and stroke is expected to rise to 14.4% from 10.7%.

The prevalence of cardiovascular disease and stroke in women is expected to rise to 14.4% from 10.7% by 2050. (iStock)

Not all trends were negative, as unhealthy cholesterol prevalence is expected to drop to about 22% from more than 42% today, the report stated.

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Dr. Elizabeth Klodas, a cardiologist and founder of Step One Foods in Minnesota, commented on these “jarring findings.”

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“The fact that on our current trajectory, cardiometabolic disease is projected to explode in women within one generation should be a huge wake-up call,” she told Fox News Digital.

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“Hypertension, diabetes, obesity — these are all major risk factors for heart disease, and we are already seeing what those risks are driving. Heart disease is the No. 1 killer of women, eclipsing all other causes of death, including breast cancer.”

Cardiovascular disease is the leading cause of death for women in the U.S. and around the world. (iStock)

Klodas warned that heart disease starts early, progresses “stealthily,” and can present “out of the blue in devastating ways.”

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The AHA published another study on Thursday revealing one million hospitalizations, showing that heart attack deaths are climbing among adults below the age of 55.

The more alarming finding, according to Klodas, is that young women were found more likely to die after their first heart attack than men of the same age.

DOCTOR SHARES 3 SIMPLE CHANGES TO STAY HEALTHY AND INDEPENDENT AS YOU AGE

“This is all especially tragic since heart disease is almost entirely preventable,” she said. “The earlier you start, the better.”

Children can show early evidence of plaque deposition in their arteries, which can be reversed through lifestyle changes if “undertaken early enough and aggressively enough,” according to the expert.

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Moving more is one part of protecting a healthy heart, according to experts. (iStock)

Klodas suggested that rising heart conditions are associated with traditional risk factors, like smoking, high blood pressure, high cholesterol, diabetes, obesity and a sedentary lifestyle.

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Doctors are also seeing higher rates of preeclampsia, or high blood pressure during pregnancy, as well as gestational diabetes. Klodas noted that these are sex-specific risk factors that don’t typically contribute to complications until after menopause.

The best way to protect a healthy heart is to “do the basics,” Klodas recommended, including the following lifestyle habits.

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Klodas especially emphasized making improvements to diet, as the food people eat affects “every single risk factor that the AHA’s report highlights.”

“High blood pressure, high blood sugar, high cholesterol, excess weight – these are all conditions that are driven in part or in whole by food,” she said. “We eat multiple times every single day, which means what we eat has profound cumulative effects over time.”

“Even a small improvement in dietary intake, when maintained, can have a massive positive impact on health,” a doctor said. (iStock)

“Even a small improvement in dietary intake, when maintained, can have a massive positive impact on health.”

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The doctor also recommends changing out a few snacks per day for healthier choices, which has been proven to “yield medication-level cholesterol reductions” in a month.

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“Keep up that small change and, over the course of a year, you could also lose 20 pounds and reduce your sodium intake enough to avoid blood pressure-lowering medications,” Klodas added.

“Women should not view the AHA report as inevitable. We have power over our health destinies. We just need to use it.”

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Vanessa Williams, 62, Opens up About Weight Loss and HRT After Menopause

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Vanessa Williams, 62, Opens up About Weight Loss and HRT After Menopause


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Common vision issue linked to type of lighting used in Americans’ homes

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Common vision issue linked to type of lighting used in Americans’ homes

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Nearsightedness (myopia) is skyrocketing globally, with nearly half of the world’s population expected to be myopic by 2050, according to the World Health Organization.

Heavy use of smartphones and other devices is associated with an 80% higher risk of myopia when combined with excessive computer use, but a new study suggests that dim indoor lighting could also be a factor.

For years, scientists have been puzzled by the different ways myopia is triggered. In lab settings, it can be induced by blurring vision or using different lenses. Conversely, it can be slowed by something as simple as spending time outdoors, research suggests.

Nearsightedness occurs when the eyeball grows too long from front to back, according to the American Optometric Association (AOA). This physical elongation causes light to focus in front of the retina rather than directly on it, making distant objects appear blurry.

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The study suggests that myopia isn’t caused by the digital devices themselves, but by the low-light environments where they are typically used. (iStock)

Researchers at the State University of New York (SUNY) College of Optometry identified a potential specific trigger for this growth. When someone looks at a phone or a book up close, the pupil naturally constricts.

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“In bright outdoor light, the pupil constricts to protect the eye while still allowing ample light to reach the retina,” Urusha Maharjan, a SUNY Optometry doctoral student who conducted the study, said in a press release.

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“When people focus on close objects indoors, such as phones, tablets or books, the pupil can also constrict — not because of brightness, but to sharpen the image,” she went on. “In dim lighting, this combination may significantly reduce retinal illumination.”

High-intensity natural light prevents myopia because it provides enough retinal stimulation to override the “stop growing” signal, even when pupils are constricted. (iStock)

The hypothesis suggests that when the retina is deprived of light during extended close-up work, it sends a signal for the eye to grow.

In a dim environment, the narrowed pupil allows so little light through that the retinal activity isn’t strong enough to signal the eye to stop growing, the researchers found.

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In contrast, being outdoors provides light levels much brighter than indoors. This ensures that even when the pupil narrows to focus on a nearby object, the retina still receives a strong signal, maintaining healthy eye development.

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The team noted some limitations of the study, including the small subject group and the inability to directly measure internal lens changes, as the bright backgrounds used to mimic the outdoors made pupils too small for standard equipment.

Researchers believe that increasing indoor brightness during close-up work could be a simple, testable way to slow the global nearsightedness epidemic. (iStock)

“This is not a final answer,” Jose-Manuel Alonso, MD, PhD, SUNY distinguished professor and senior author of the study, said in the release.

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“But the study offers a testable hypothesis that reframes how visual habits, lighting and eye focusing interact.”

The study was published in the journal Cell Reports.

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