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Actor Eric Dane’s death from ALS sparks urgent focus on rapid decline

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Actor Eric Dane’s death from ALS sparks urgent focus on rapid decline

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Eric Dane’s death has sparked conversations about the speed and severity of ALS.

Also known as Lou Gehrig’s disease, the progressive illness — officially called amyotrophic lateral sclerosis — is debilitating and fatal. 

While only about 5,000 people in the U.S. are diagnosed each year, the average life expectancy is just two to five years, according to the ALS Association.

Dane, who most famously starred as Dr. Mark “McSteamy” Sloan on ABC’s “Grey’s Anatomy,” announced his diagnosis in April 2025, telling “Good Morning America” in June that his first symptoms began as “some weakness” in his right hand.

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‘GREY’S ANATOMY’ STAR ERIC DANE DEAD AT 53

“I didn’t really think anything of it,” the actor said. “At the time, I thought maybe I’d been texting too much, or my hand was fatigued. But a few weeks later, I noticed that it got a little worse.”

“I’m fighting as much as I can,” Dane added. “There’s so much about it that’s out of my control.”

Eric Dane starred as Dr. Mark “McSteamy” Sloan on “Grey’s Anatomy” for seven seasons. (Bob D’Amico/Disney General Entertainment Content via Getty Images)

What is ALS?

ALS is a progressive disease where the brain loses connection with the muscles, according to the ALS Association. This slowly strips a person’s ability to walk, talk, eat, dress, write, speak, swallow and, eventually, breathe.

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Early signs include muscle weakness, stiffness and cramping. Symptom progression and severity are different for each case, as the association notes there is “no single timeline for ALS.”

REBECCA GAYHEART STEPS UP AS CAREGIVER FOR ESTRANGED HUSBAND ERIC DANE AS ALS DEMANDS 24-HOUR CARE

The disease only impacts motor neurons controlling voluntary movement, so the five senses — sight, touch, hearing, taste and smell — are not affected, nor are the eye muscles or bladder control.

ALS symptoms typically begin with muscle weakness in the upper extremities. (iStock)

Many ALS patients remain “mentally alert and aware” throughout the disease, the ALS Association reported.

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Diagnosis typically occurs in people between the ages of 40 and 70. About 20% of patients live five years or longer. Only about 5% live longer than 20 years.

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ALS is typically diagnosed by a neurologist with an electromyography test (EMG), but can also be detected by blood and urine tests, spinal taps, MRIs and other imaging scans, muscle and nerve biopsies, or neurological exams.

There is currently no cure or treatment to stop disease progression, although there are treatments to slow and ease symptoms, per the ALS Association.

ALS can be diagnosed by a neurologist through various forms of testing. (iStock)

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Fox News senior medical analyst Dr. Marc Siegel joined “Fox & Friends” on Friday to discuss the prevalence of ALS, suggesting that cases have increased due to “something in the environment that we don’t know yet.”

While ALS is 10% genetic, according to Siegel, 90% of cases do not have a genetic link, pointing toward other risk factors like environmental toxins.

“We’re learning to personalize the approach to this disease.”

“It’s a muscle weakness disease — affecting nerves that innervate muscles — and usually it starts on one side,” the doctor shared. “Then you develop fatigue … You could see a quivering tongue or your arm is quivering, usually one side and then the other side.”

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As the weakness progresses, it impacts speech and ultimately attacks the diaphragm, making it difficult to fully inflate the lungs.

“That’s what happened to [Dane], most likely,” Siegel said. “So, it progresses from your arms, your legs, your speech, your swallowing ability and then your breathing.”

Rising research

ALS progresses “pretty rapidly in most cases,” Siegel said. While scientist Stephen Hawking lived 55 years with the disease, Dane “probably lived about two years with it,” the doctor surmised.

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“I want to point out how courageous [Dane] is — he actually was involved with Target ALS, where he was fighting for new research,” Siegel pointed out. “We’re learning to personalize the approach to this disease, and that’s the future — and he fought for that.”

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Actor Eric Dane is photographed at the St. Regis in Washington, D.C., on Sept. 30, 2025. “I want to point out how courageous [Dane],” said Dr. Marc Siegel. (Marvin Joseph/The Washington Post via Getty Images)

“We need a lot of money for research for this — [Dane] was asking for a billion dollars from the government.”

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Various research groups and hospital systems are actively working on new ALS therapies that take a personalized approach, Siegel shared.

The estimated cost to develop a drug that would slow or stop disease progression is $2 billion, the ALS Association has reported. The annual estimated out-of-picket cost for care is $250,000.

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Funding for ALS research and awareness has been on the rise for years, with the viral social media ALS Ice Bucket Challenge making a splash in 2014. 

The challenge, supported by the ALS Association, was intended to boost awareness. It ultimately raised $115 million toward ALS research and patient care.

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The Mental Trick That Ends Compulsive Eating and Makes Weight Loss Easier

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The Mental Trick That Ends Compulsive Eating and Makes Weight Loss Easier


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How To Stop Compulsive Eating and Make Weight Loss Easier




















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Popular weight-loss drugs linked to unexpected male fertility benefit

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Popular weight-loss drugs linked to unexpected male fertility benefit

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Taking a GLP-1 medication for weight loss may improve male fertility, according to experts.

Research presented this week at ENDO 2026, the Endocrine Society’s annual meeting in Chicago, explored how obesity is strongly linked to fertility problems in men.

Excess weight can contribute to dysregulation of the hypothalamic-pituitary-gonadal (HPG) axis — the hormone system that regulates testosterone production — and functional hypogonadism, a condition in which testosterone levels are abnormally low because of disrupted hormone signaling. These changes can also impair semen quality.

WEIGHT-LOSS MEDICATIONS COULD IMPACT SEXUAL HEALTH IN UNEXPECTED WAYS

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The researchers evaluated how GLP-1 weight-loss drugs impact reproductive hormones and metabolic outcomes, analyzing data of men between the ages of 18 and 65 who were taking one of the medications, according to a press release.

The systematic review of five randomized controlled trials focused on measuring testosterone, brain hormones involved in testosterone and sperm production, and a protein that carries sex hormones in the blood. Semen quality, weight and BMI, cholesterol and blood sugar were also measured.

Men with obesity and low testosterone linked to obesity may experience improved testosterone, sperm quality and metabolic heath while taking a GLP-1, the study found. (iStock)

The results suggested that GLP-1 medications do not suppress male hormones. Men with obesity and low testosterone linked to obesity may experience improved testosterone, sperm quality and metabolic health, especially during weight loss.

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In one four-week study, dulaglutide showed no significant changes in reproductive hormones or sexual function.

In a separate 16-week trial, liraglutide improved hormones in obese men with functional hypogonadism, meaning low testosterone was likely related to obesity. The review found that liraglutide was better for health outcomes than hormone replacement therapy.

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Another liraglutide study reported improved sperm concentration and count.

The study authors concluded that GLP-1s “do not appear to acutely suppress the male HPG axis and may improve reproductive hormones and semen parameters in obese hypogonadal men, largely within the context of weight loss.” (iStock)

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A 24-week trial of semaglutide, known commercially as Ozempic and Wegovy, saw improvement in sperm shape and bad cholesterol, while preserving total testosterone.

As only five trials were included, the small evidence base suggests more research is necessary to prove further association.

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In an abstract of the research, the authors summed up that GLP-1s “do not appear to acutely suppress the male HPG axis and may improve reproductive hormones and semen parameters in obese hypogonadal men, largely within the context of weight loss.”

“However, evidence remains limited and heterogeneous, underscoring the need for larger RCTs explicitly powered to assess male reproductive outcomes,” they wrote.

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“This provides early evidence that GLP-1 medications taken by obese men with hypogonadism/low testosterone (low T) improves testosterone levels,” one doctor said. (iStock)

Dr. Anthony Puopolo, men’s health expert and lead medical provider for RexMD, reflected on these findings in an interview with Fox News Digital.

“This provides early evidence that GLP-1 medications taken by obese men with hypogonadism/low testosterone (low T) improves testosterone levels,” he said.

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While more research is necessary, Pupolo, who was not involved in the study, shared his optimism about how GLP-1s can play a role in improving male fertility.

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“If this finding continues to gain evidence, GLP-1s might be a better option for low T than testosterone replacement therapy (TRT) in obese men – as GLP-1 medications preserve fertility, whereas TRT tends to be harmful to male reproductive/sperm function,” he added.

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Measles-infected traveler may have exposed passengers at LAX and nearby hotel, health officials warn

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Measles-infected traveler may have exposed passengers at LAX and nearby hotel, health officials warn

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A traveler infected with measles may have exposed passengers at Los Angeles International Airport and guests at a nearby hotel after arriving in Los Angeles County earlier this month, health officials said Wednesday.

The Los Angeles County Department of Public Health said it is investigating a confirmed measles case involving a traveler who arrived aboard Cathay Pacific Flight CX 884 on June 11. The traveler was infectious while passing through Los Angeles County, potentially exposing others at LAX and the Hilton Los Angeles Airport Hotel.

The case marks the sixth measles infection reported in Los Angeles County this year. Health officials said the risk of exposure could increase as summer travel ramps up and Los Angeles welcomes international visitors for FIFA World Cup events being held in the region.

MEASLES CASES CONFIRMED AT FOUR MAJOR US AIRPORTS ACROSS COUNTRY AMID PEAK HOLIDAY TRAVEL

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A 3D illustration shows measles virus particles. (iStock)

According to health officials, anyone who was at the Tom Bradley International Terminal between 10 a.m. and noon on June 11 may have been exposed. Officials also identified a potential exposure at the Hilton Los Angeles Airport Hotel, located at 5711 W. Century Blvd., between 11:15 a.m. and 12:15 p.m. that same day.

The Centers for Disease Control and Prevention is working with local health departments to notify passengers who were seated near the infected traveler on the international flight.

People who were at either location during the listed times could develop symptoms between seven and 21 days after exposure, officials said. The last day to monitor for symptoms is July 2.

AT LEAST 46 CHILDREN DEAD AMID MEASLES OUTBREAK AS VIRUS SPREADS GLOBALLY

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Los Angeles International Airport is seen in Los Angeles, California. Health officials said a traveler infected with measles may have exposed passengers at LAX on June 11. (Michael Yanow/NurPhoto)

“As measles cases increase, it is important that residents take steps to make sure they are fully protected,” Los Angeles County Health Officer Dr. Muntu Davis said. “The MMR vaccine is the safest and most reliable way to prevent measles and protect yourself, your family, and your community.”

Travelers exit a terminal at Los Angeles International Airport in Los Angeles on Monday, March 23, 2026. (Ethan Swope/AP Photo)

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Symptoms include fever, cough, runny nose, red and watery eyes, followed by a rash that typically begins on the face before spreading to the rest of the body.

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Fox News Digital reached out to the Los Angeles County Department of Public Health for additional comment but did not receive a response.

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