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Common respiratory bacteria detected in eyes of Alzheimer’s patients

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Common respiratory bacteria detected in eyes of Alzheimer’s patients

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A bacterium prevalent in sinus infections and pneumonia may aggravate Alzheimer’s disease, according to a recent study published in Nature Communications. 

The bacterium, Chlamydia pneumoniae, was found in the eyes of deceased patients with Alzheimer’s disease, according to researchers from Cedars-Sinai’s Health Sciences University in California.

“The retina is directly connected with the brain. It’s a developmental extension of the brain,” lead researcher Maya Koronyo-Hamaoui, PhD, professor of neurosurgery, neurology and biomedical sciences at Cedars-Sinai Health Sciences University, told Fox News Digital.

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Eye-brain link

The study showed that Chlamydia pneumoniae could reach the retinal tissue that lines the back of the eye and linger for several years, creating an inflammatory response potentially linked to the death of nerve cells. This could contribute to cognitive decline and could worsen Alzheimer’s disease symptoms. 

A bacterium prevalent in sinus infections and pneumonia may aggravate Alzheimer’s disease, according to a recent study published in Nature Communications.  (iStock)

The findings point to potential therapies for Alzheimer’s disease that would target inflammation and provide antibiotic treatment in the early stages of infection, according to Koronyo-Hamaoui.

“One hope of this study is that when people do present with some [symptoms of] pneumonia or atypical pneumonia or some respiratory infection, doctors should consider testing specifically for Chlamydia pneumoniae, and then give them the specific antibiotic,” the researcher said.

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The infection can be identified through laboratory testing, including PCR (polymerase chain reaction), blood tests, or cultures that allow live organisms to grow for analysis.

Inside the study

The researchers examined retinal tissue samples from over 100 deceased individuals who fell into three groups: those who had Alzheimer’s disease, those who had some cognitive deficit or those who did not have the disease. 

“The retina is directly connected with the brain. It’s a developmental extension of the brain,” the lead researcher said. (iStock)

They analyzed proteins, conducted genetic testing and used advanced imaging techniques on the samples. Those with Alzheimer’s disease had higher levels of the bacterium in their brains and retinal tissue compared to those who had normal cognition, the release stated.

Genetic risk

Higher levels of chlamydia pneumonia were found in those who carried the gene variant APOE4, which is an associated risk factor for Alzheimer’s disease, Koronyo-Hamaoui added. The bacterium was also associated with more severe cognition decline.  

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Those with Alzheimer’s disease had higher levels of the bacterium in their brains and retinal tissue compared to those who had normal cognition. (iStock)

The Cedars-Sinai team also looked at human neurons and lab mice with Alzheimer’s disease, finding that Chlamydia pneumoniae was linked to increased inflammation, nerve cell death and cognitive decline, further suggesting that it may play a role in accelerating the disease. 

The infection also prompted production of amyloid-beta, which is a protein known to accumulate in the brains of those with Alzheimer’s, Koronyo-Hamaoui said.

While the study points toward using the retina as a way to diagnose and monitor the disease, the researcher acknowledged that more research is needed to confirm these findings.

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Experts urge caution

Dr. Aaron Glatt, chief of infectious diseases at Mount Sinai South Nassau on Long Island, New York, was not involved with the study but called the findings “interesting.” 

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Glatt, who is also a spokesperson for the Infectious Diseases Society of America, emphasized that the findings only show an association and not causation, and that much more clinical research is needed.

“It does not mean infections cause Alzheimer’s or that people should worry about past respiratory illnesses.”

“Chlamydia pneumoniae is a very common respiratory pathogen that many people are exposed to throughout their lives,” he told Fox News Digital. “While the study identifies a link between this bacterium and neurodegeneration, a standard sinus infection does not mean a patient will develop Alzheimer’s.”

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The key takeaway, according to Glatt, is that the study opens new doors for potential diagnostics and treatments, but is “not a reason for immediate alarm regarding common infections.”

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Dr. Sharon Fekrat, MD, a clinical spokesperson for the American Academy of Ophthalmology and a retina specialist at the Duke University School of Medicine in North Carolina, agreed that the findings could help researchers better understand how inflammation may drive disease progression and “could lead to new ways to detect or treat Alzheimer’s in the future.”

The infection also prompted production of amyloid-beta, which is a protein known to accumulate in the brains of those with Alzheimer’s. (iStock)

“This is early research suggesting that infection-related inflammation may worsen Alzheimer’s disease in people who are already vulnerable,” Fekrat, who also did not work on the study, told Fox News Digital. “It does not mean infections cause Alzheimer’s or that people should worry about past respiratory illnesses.”

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What’s next

While some teams are developing and testing retinal imaging tools in living patients, those methods are not yet part of routine clinical screenings or diagnosis, Fekrat noted.

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For now, the best proven steps include following brain-healthy habits, such as managing cardiovascular risk factors, staying mentally and socially engaged, and seeking medical care for any cognitive symptoms, the expert added.

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Seniors over 80 who eat specific diet may be less likely to reach 100 years old

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Seniors over 80 who eat specific diet may be less likely to reach 100 years old

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Older adults who avoid meat in their golden years may be less likely to reach age 100 than their meat-eating counterparts, new research suggests.

Researchers tracked more than 5,000 adults aged 80 or older who were enrolled in the Chinese Longitudinal Healthy Longevity Survey.

Between 1998 and 2018, data showed that those who did not eat meat were less likely to reach their 100th birthday than those who consumed animal products regularly.

The findings seem to contradict previous studies that have linked vegetarianism and plant-based diets to lower risks of heart disease, stroke, diabetes and obesity.

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Most evidence supporting the benefits of plant-based diets comes from studies tracking younger populations, the researchers noted. 

The findings contrast with previous research praising plant-based diets for their positive influence on heart health. (iStock)

The study, published in The American Journal of Clinical Nutrition, points to losses in muscle mass and bone density with age, shifts that can increase the risk of malnutrition and frailty in the “oldest old.”

As people enter their 80s and 90s, the nutritional priority often shifts from preventing long-term chronic diseases to maintaining day-to-day physical function, experts say.

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“The headline ‘vegetarians over 80 less likely to reach 100’ sounds surprising, because it contrasts with decades of data linking plant‑forward diets to lower chronic disease risk earlier in life,” Erin Palinski-Wade, a New Jersey-based registered dietitian, told Fox News Digital. 

“However, once you see that this research is limited to adults over the age of 80 who are also underweight — and that this link disappears with the consumption of eggs, dairy and fish — the results are less surprising.”

While diets earlier in life tend to emphasize avoiding long-term disease, older age necessitates nutrients and weight maintenance, experts say. (iStock)

In those over 80, restricting animal proteins may be less likely to promote longevity, according to Palinski-Wade, who was not involved in the study.

Eliminating all animal protein — particularly in a population that may already experience diminished hunger cues — can make it more difficult to meet adequate protein needs, potentially increasing the risk of nutrient deficiencies, the nutritionist said.

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In addition to a higher tendency to be underweight, older populations also face a greater risk of bone fractures due to lower calcium and protein intake.

Potential limitations

The lower rate of vegetarians reaching 100 was only observed in participants identified as underweight, the researchers noted. No such association was found in people who maintained a healthy weight.

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Because being underweight is already linked to greater frailty and mortality risk, the researchers noted that body weight may partly explain the findings, making it difficult to determine whether diet itself played a direct role.

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Those incorporating animal-sourced products other than meat were just as likely to live to 100. (iStock)

Additionally, the shortened lifespans were not found in people who continued to eat non-meat animal products, such as fish, dairy and eggs. 

Older adults with these more flexible diets were just as likely to live to 100 as those eating meat, as these foods may provide the nutrients necessary for maintaining muscle and bone health, the researchers noted.

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“This is an observational study, so it can only show associations, and does not prove that avoiding meat directly reduces the odds of reaching 100,” Palinski-Wade added.

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The researchers suggested that including small amounts of animal-sourced foods could help older seniors maintain essential nutrients and avoid the muscle loss often seen in those who stick strictly to plants.

Eliminating all animal protein — particularly in a population that may already experience diminished hunger cues — can make it more difficult to meet adequate protein needs, potentially increasing the risk of nutrient deficiencies. (iStock)

Palinski-Wade offered some guidance for those looking to optimize nutrition later in life.

“For adults in their 80s and beyond, especially anyone losing weight or muscle, the priority should be maintaining a healthy weight and meeting protein and micronutrient needs — even if that means adding or increasing fish, eggs, dairy or well‑planned, fortified plant proteins and supplements.”

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Strict vegan or very low‑protein patterns at that age should be carefully monitored by a dietitian or clinician, with attention to B12, vitamin D, calcium and total protein, according to Palinski-Wade.

“Younger and healthier adults can still confidently use plant‑forward or vegetarian patterns to lower long‑term chronic disease risk,” she added.

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The Latest on Natural Ozempic Alternatives: How To Lose Weight Without GLP-1s

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The Latest on Natural Ozempic Alternatives: How To Lose Weight Without GLP-1s


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Punch the monkey, viral star, experiences dramatic breakthrough among zoo mates

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Punch the monkey, viral star, experiences dramatic breakthrough among zoo mates

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In a dramatic turn of events that’s captured the attention of animal lovers worldwide, Punch — the young macaque at a zoo in Japan famous for his inseparable bond with a stuffed orangutan toy — has reached a major milestone in his journey toward social integration.

On Thursday, visitors and staff at the Ichikawa Zoological and Botanical Garden witnessed a breakthrough: Punch was seen cuddling with and hitching a ride on the back of a fellow macaque.

Punch’s story began with hardship. He was abandoned by his mother shortly after his birth in July 2025 — and to ensure his survival, zookeepers stepped in to hand-rear the primate.

On Jan. 19, 2026, the zoo officially began the process of reintegrating Punch into the “monkey mountain” enclosure.

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The transition was initially fraught with tension. 

Punch’s story began with hardship when he was abandoned by his mother shortly after he was born. To help him, zookeepers gave him a stuffed toy that he began dragging around everywhere he went.  (David Mareuil/Anadolu via Getty Images)

As a hand-reared infant, Punch was bullied and ignored by the established group of monkeys.

He was often seen huddled alone with his orange plush companion while the rest of the troop interacted.

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In an official statement released Feb. 27, the Ichikawa Zoological and Botanical Garden detailed the meticulous care behind this process.

Previous viral videos showed Punch bullied by the rest of the troop, running to his plushy toy for comfort. (David Mareuil/Anadolu via Getty Images)

“From an animal welfare perspective, our primary goal is to reintegrate Punch with the troop,” the zoo said. 

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The strategy involved nursing Punch within the enclosure, so the troop could recognize him as one of their own, and pairing him with a gentle young female macaque prior to his full release to build his confidence.

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The latest footage, captured by X user @tate_gf, suggested the zoo’s patience is paying off. 

The video shows Punch seeking physical contact not from his toy, but from another monkey — eventually climbing onto its back for a vital social behavior for young macaques: the “piggyback ride.”

The zoo’s strategy appears to be paying off: Punch, shown at far left, was recently seen riding on the back of a fellow macaque. (David Mareuil/Anadolu via Getty Images)

While Punch still carries his stuffed toy for comfort during moments of perceived danger, the zoo remains optimistic about his progress. 

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The organization cited the successful 2009 case of Otome, another hand-reared macaque who eventually outgrew her stuffed toy, successfully integrated — and went on to raise four offspring of her own.

The zoo has had crowds coming to see Punch, with hundreds of people lining up to get inside to see the young star, according to reports. 

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“I’m hoping Punch has a good life like everybody else does, and think he’s a cute little guy,” one person commented online. 

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“Such a precious baby,” another person wrote. 

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