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NFL and UFC athletes try 'game-changing' psychedelic to treat brain injury

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NFL and UFC athletes try 'game-changing' psychedelic to treat brain injury

As awareness grows around the dangers of head trauma in sports, a small number of professional fighters and football players are turning to a psychedelic called ibogaine for treatment.

Ibogaine, which is derived from a West African shrub, is a Schedule 1 drug in America with no legal medical uses, and experts urge caution because of the need for further studies. But the results, several athletes say, are “game-changing.”

“It saved my life,” said former NFL offensive guard Robert Gallery, who traveled to Mexico in 2023 to try ibogaine.

“I’m not anxious all the time, I’m not depressed,” he continued, “I can go for a run and be thankful that I’m alive, rather than having a thought that I should step in front of a semi-truck coming down the road.”

The psychedelic substance is derived from the iboga plant, and proponents tout its ability to treat addiction, post-traumatic stress disorder and traumatic brain injury, or TBI.

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An observational study of 30 special forces veterans by researchers at Stanford University suggests that ibogaine can be highly effective at reducing anxiety, depression and cognitive challenges associated with TBI.

“This is a miraculous thing,” said retired MMA fighter Tait Fletcher, who credits the treatment with freeing him from suicidal ideation.

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NFL Hall of Fame quarterback Brett Favre even tried ibogaine to see if it could help his Parkinson’s, a neurodegenerative disease linked to TBI.

Although athletes are just discovering ibogaine, the drug is well known within the veteran community, which experiences high rates of brain injury and PTSD.

In Stanford’s study on the effects of ibogaine on special forces veterans, participants saw average reductions of 88% in PTSD symptoms, 87% in depression symptoms and 81% in anxiety symptoms. They also exhibited improvements in concentration, information processing and memory.

“No other drug has ever been able to alleviate the functional and neuropsychiatric symptoms of traumatic brain injury,” Dr. Nolan Williams, a professor of psychiatry and behavioral sciences, said in a statement on the results. “The results are dramatic, and we intend to study this compound further.”

A capsule containing a therapeutic dose of ibogaine.

A capsule containing a therapeutic dose of ibogaine, a psychedelic used to help treat traumatic brain injury, PTSD and addiction. (Magda Stuglik)

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A team member at Ambio Life Sciences in Tijuana prepares a dosage of ibogaine.

A team member at Ambio Life Sciences in Tijuana prepares a dose of the drug. (Magda Stuglik)

To receive federal approval, ibogaine would need to pass through multiple phases of clinical trials at the Food and Drug Administration and be moved by the Drug Enforcement Administration to a less restrictive drug category.

Schedule 1 drugs are considered to have no federally accepted medical use, a high potential for abuse and a lack of accepted safety. They also include psilocybin, MDMA, LSD and marijuana.

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States can work faster than the federal government by carving out exemptions for supervised ibogaine therapy programs, similar to what Oregon has done with psilocybin therapy. Many states have also opted to legalize marijuana for medicinal or recreational use.

Study co-author Dr. Ian Kratter said researchers have reported that ibogaine may stimulate brain healing by causing an increase in certain neurotrophic factors.

“These factors signal for enhanced brain cell survival and synaptic plasticity, which is the ability for brain cells to modify the strength of their connections or even form new connections,” said Kratter, a professor of psychiatry and behavioral sciences. “This might facilitate a healing and recovery process after an injury.”

A darkened room with a bed and soft lighting and some medical monitors.

Ambio Life Sciences has administered ibogaine to hundreds of veterans since opening in 2021.

(Magda Stuglik)

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Dr. Kevin Bickart, a UCLA neurology professor who specializes in brain injury in athletes, said that the Stanford study is “remarkably promising” and that it is reasonable to believe professional athletes could experience similar results.

“This group [veterans] is a strong analogue for retired professional athletes from high-contact sports like football or hockey who are now dealing with persistent cognitive and emotional difficulties,” he said.

Dr. Ramon Diaz-Arrastia, director of Penn Medicine’s TBI research center, said that ibogaine is “one of the more promising compounds” for treatment of TBI.

However, Bickart, Diaz-Arrastia and the Stanford researchers all emphasized the need for larger, randomized controlled trials demonstrating a strong therapeutic benefit and safety profile prior to the treatment being used in America.

They also highlighted the fact that ibogaine can cause heart problems such as cardiac arrhythmia and needs to be administered under strict medical supervision. In the Stanford study, cardiac monitoring and magnesium were used to mitigate this danger, and researchers reported that no participants experienced adverse cardiac effects.

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Gallery heard about ibogaine when listening to a podcast about veterans whose struggles resonated with his own. He was at the end of his rope and willing to try anything to free himself from dark thoughts and the ringing noise inside his head.

“It was kind of a last-ditch hope for me,” he said. “I was just at that place of needing the noise and the thoughts to stop.”

Gallery’s doctor believes he likely developed CTE (chronic traumatic encephalopathy) as a result of repeated brain injuries during his eight seasons in the NFL. CTE, which can only be diagnosed after death, is a severe neurodegenerative disease that can cause dementia, violent mood swings, loss of motor control and depression.

Many famous athletes who committed suicide were later determined to have CTE, including New England Patriots tight end Aaron Hernandez, Hall of Fame linebacker Junior Seau and Chicago Bears safety Dave Duerson.

A football player lifts another football player into the air.

Former NFL offensive guard Robert Gallery, who played for the Raiders, credits ibogaine therapy with saving his life and relationship with his family.

(Robert Gallery)

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Fletcher, the former MMA fighter who is also an actor and stunt artist, heard about ibogaine through his Navy SEAL friends.

He had experienced many concussions during his fighting career, but it was head trauma during a stunt gone wrong in 2019 that pushed him over the edge and into an extremely dark place.

The following morning he woke up in a state of terror. He didn’t know how to pack his bags or get out of the hotel room he had been staying in for the shoot.

Fletcher spent the next year in near-total seclusion, largely unable to leave his house due to light and sound sensitivity. Like Gallery, he tried many conventional and experimental therapies, but nothing compared with the relief that ibogaine brought him in 2023.

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“We’re putting Band-Aids on problems through pharmacology,” he said. “This [ibogaine] is a thing that I watched just set people free. Nothing short of that.”

Keith Jardine, a former UFC fighter, was inspired by Fletcher’s story and traveled to Mexico to receive treatment himself. Retired hockey player Ales Hemsky credits ibogaine with helping free him of the substance use and alcohol dependency that he struggled with after his 16-year career in the NHL.

“It’s been seven months now I haven’t had a sip of alcohol,” he said. “It’s life-changing. It really restarts your brain. It gives you a new path.”

Fletcher has seen the darkness brain injury brings to athletes and the light ibogaine provides. He wants both to be part of a bigger conversation in the professional sports world.

Tait Fletcher, stuntman and former MMA fighter, suffered traumatic brain injury.

Tait Fletcher, stuntman and former MMA fighter, suffered traumatic brain injury as a result of multiple concussive events during his career.

(Paul Mobley)

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“I wish that these big organizations were looking into these things differently, because you could elongate careers and elongate lives,” he said. “And ibogaine is certainly a part of that conversation.”

Favre also wants to see more attention brought to speeding up medical trials of new treatments for brain injury and related conditions. After taking ibogaine, his Parkinson’s symptoms disappeared for three days before gradually returning, he said.

“I’m not disappointed by anything. I’m more excited about the opportunity knowing that I could do it again,” he said. “I’m hoping that this [conversation] helps open the door for not just ibogaine or psychedelic drugs, but just medication or treatments in general that can help people.”

Bickart said there is a major gap in effective, approved treatments for the persistent symptoms of brain injury.

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“This leaves many, including veterans and potentially former athletes, without reliable solutions for ongoing disability, cognitive difficulties, and psychiatric conditions like PTSD, depression, and anxiety that can stem from head injuries,” he said.

Inspired by his own experience with ibogaine, Gallery co-founded a nonprofit called Athletes for Care to educate athletes with TBI on treatment options and advocate for research into psychedelic-assisted therapies.

“The sports community is not very good about talking about mental health,” he said. “Seeing the veterans take charge and take care of their community, I want to do that for the sports community and for my friends that I know that are out there suffering.”

Brett Favre visited Ambio Life Sciences clinic.

NFL Hall of Fame quarterback Brett Favre, at left with Ambio’s Trevor Millar, visited the clinic in Mexico to seek treatment for Parkinson’s disease.

(Trevor Millar)

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Gallery, Favre, Hemsky, Fletcher and Jardine are among around a dozen retired contact-sports athletes who have received treatment at the Ambio Life Sciences clinic in Tijuana, which is a popular destination for ibogaine therapy.

Since opening in 2021, Ambio reports administering ibogaine to more than 3,000 patients, including 1,000 military veterans.

Diaz-Arrastia, the Penn Medicine professor, said he would not advise that Americans order ibogaine online or travel outside the country for treatment, as it remains unregulated, with limited research. Bickart, the UCLA professor, echoed these concerns, noting that the most critical caution is safety.

“People should be wary of any unregulated treatments, as the purity dosage and presence of contaminants are often unknown,” Bickart said. “The placebo effect can also be very powerful, especially for treatments that require significant effort and cost.”

Ambio, the clinic that Stanford researchers worked with for their observational study on ibogaine, stressed its safety protocols during treatment, including close monitoring of dosage and patients’ cardiac health.

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There is growing political and scientific momentum in America for more clinical research of ibogaine.

In June, Texas approved a historic $50-million investment in state funding to support drug development trials for ibogaine, inspired by the results seen by veterans.

Arizona legislators approved $5 million in state funding for a clinical study on ibogaine in March, and California legislators are pushing to fast-track the study of ibogaine and other psychedelics.

“Honestly, I’m amazed to see how much interest there is in ibogaine now,” said Ambio co-founder Jonathan Dickinson. “We’re starting to see things that we would have thought were unimaginable several years ago.”

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Diablo Canyon clears last California permit hurdle to keep running

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Diablo Canyon clears last California permit hurdle to keep running

Central Coast Water authorities approved waste discharge permits for Diablo Canyon nuclear plant Thursday, making it nearly certain it will remain running through 2030, and potentially through 2045.

The Pacific Gas & Electric-owned plant was originally supposed to shut down in 2025, but lawmakers extended that deadline by five years in 2022, fearing power shortages if a plant that provides about 9 percent the state’s electricity were to shut off.

In December, Diablo Canyon received a key permit from the California Coastal Commission through an agreement that involved PG&E giving up about 12,000 acres of nearby land for conservation in exchange for the loss of marine life caused by the plant’s operations.

Today’s 6-0 vote by the Central Coast Regional Water Board approved PG&E’s plans to limit discharges of pollutants into the water and continue to run its “once-through cooling system.” The cooling technology flushes ocean water through the plant to absorb heat and discharges it, killing what the Coastal Commission estimated to be two billion fish each year.

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The board also granted the plant a certification under the Clean Water Act, the last state regulatory hurdle the facility needed to clear before the federal Nuclear Regulatory Commission (NRC) is allowed to renew its permit through 2045.

The new regional water board permit made several changes since the last one was issued in 1990. One was a first-time limit on the chemical tributyltin-10, a toxic, internationally-banned compound added to paint to prevent organisms from growing on ship hulls.

Additional changes stemmed from a 2025 Supreme Court ruling that said if pollutant permits like this one impose specific water quality requirements, they must also specify how to meet them.

The plant’s biggest water quality impact is the heated water it discharges into the ocean, and that part of the permit remains unchanged. Radioactive waste from the plant is regulated not by the state but by the NRC.

California state law only allows the plant to remain open to 2030, but some lawmakers and regulators have already expressed interest in another extension given growing electricity demand and the plant’s role in providing carbon-free power to the grid.

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Some board members raised concerns about granting a certification that would allow the NRC to reauthorize the plant’s permits through 2045.

“There’s every reason to think the California entities responsible for making the decision about continuing operation, namely the California [Independent System Operator] and the Energy Commission, all of them are sort of leaning toward continuing to operate this facility,” said boardmember Dominic Roques. “I’d like us to be consistent with state law at least, and imply that we are consistent with ending operation at five years.”

Other board members noted that regulators could revisit the permits in five years or sooner if state and federal laws changes, and the board ultimately approved the permit.

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Deadly bird flu found in California elephant seals for the first time

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Deadly bird flu found in California elephant seals for the first time

The H5N1 bird flu virus that devastated South American elephant seal populations has been confirmed in seals at California’s Año Nuevo State Park, researchers from UC Davis and UC Santa Cruz announced Wednesday.

The virus has ravaged wild, commercial and domestic animals across the globe and was found last week in seven weaned pups. The confirmation came from the U.S. Department of Agriculture’s National Veterinary Services Laboratory in Ames, Iowa.

“This is exceptionally rapid detection of an outbreak in free-ranging marine mammals,” said Professor Christine Johnson, director of the Institute for Pandemic Insights at UC Davis’ Weill School of Veterinary Medicine. “We have most likely identified the very first cases here because of coordinated teams that have been on high alert with active surveillance for this disease for some time.”

Since last week, when researchers began noticing neurological and respoiratory signs of the disease in some animals, 30 seals have died, said Roxanne Beltran, a professor of ecology and evolutionary biology at UC Santa Cruz. Twenty-nine were weaned pups and the other was an adult male. The team has so far confirmed the virus in only seven of the dead pups.

Infected animals often have tremors convulsions, seizures and muscle weakness, Johnson said.

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Beltran said teams from UC Santa Cruz, UC Davis and California State Parks monitor the animals 260 days of the year, “including every day from December 15 to March 1” when the animals typically come ashore to breed, give birth and nurse.

The concerning behavior and deaths were first noticed Feb. 19.

“This is one of the most well-studied elephant seal colonies on the planet,” she said. “We know the seals so well that it’s very obvious to us when something is abnormal. And so my team was out that morning and we observed abnormal behaviors in seals and increased mortality that we had not seen the day before in those exact same locations. So we were very confident that we caught the beginning of this outbreak.”

In late 2022, the virus decimated southern elephant seal populations in South America and several sub-Antarctic Islands. At some colonies in Argentina, 97% of pups died, while on South Georgia Island, researchers reported a 47% decline in breeding females between 2022 and 2024. Researchers believe tens of thousands of animals died.

More than 30,000 sea lions in Peru and Chile died between 2022 and 2024. In Argentina, roughly 1,300 sea lions and fur seals perished.

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At the time, researchers were not sure why northern Pacific populations were not infected, but suspected previous or milder strains of the virus conferred some immunity.

The virus is better known in the U.S. for sweeping through the nation’s dairy herds, where it infected dozens of dairy workers, millions of cows and thousands of wild, feral and domestic mammals. It’s also been found in wild birds and killed millions of commercial chickens, geese and ducks.

Two Americans have died from the virus since 2024, and 71 have been infected. The vast majority were dairy or commercial poultry workers. One death was that of a Louisiana man who had underlying conditions and was believed to have been exposed via backyard poultry or wild birds.

Scientists at UC Santa Cruz and UC Davis increased their surveillance of the elephant seals in Año Nuevo in recent years. The catastrophic effect of the disease prompted worry that it would spread to California elephant seals, said Beltran, whose lab leads UC Santa Cruz’s northern elephant seal research program at Año Nuevo.

Johnson, the UC Davis researcher, said the team has been working with stranding networks across the Pacific region for several years — sampling the tissue of birds, elephant seals and other marine mammals. They have not seen the virus in other California marine mammals. Two previous outbreaks of bird flu in U.S. marine mammals occurred in Maine in 2022 and Washington in 2023, affecting gray and harbor seals.

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The virus in the animals has not yet been fully sequenced, so it’s unclear how the animals were exposed.

“We think the transmission is actually from dead and dying sea birds” living among the sea lions, Johnson said. “But we’ll certainly be investigating if there’s any mammal-to-mammal transmission.”

Genetic sequencing from southern elephant seal populations in Argentina suggested that version of the virus had acquired mutations that allowed it to pass between mammals.

The H5N1 virus was first detected in geese in China in 1996. Since then it has spread across the globe, reaching North America in 2021. The only continent where it has not been detected is Oceania.

Año Nuevo State Park, just north of Santa Cruz, is home to a colony of some 5,000 elephant seals during the winter breeding season. About 1,350 seals were on the beach when the outbreak began. Other large California colonies are located at Piedras Blancas and Point Reyes National Sea Shore. Most of those animals — roughly 900 — are weaned pups.

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It’s “important to keep this in context. So far, avian influenza has affected only a small proportion of the weaned at this time, and there are still thousands of apparently healthy animals in the population,” Beltran said in a press conference.

Public access to the park has been closed and guided elephant seal tours canceled.

Health and wildlife officials urge beachgoers to keep a safe distance from wildlife and keep dogs leashed because the virus is contagious.

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When slowing down can save a life: Training L.A. law enforcement to understand autism

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When slowing down can save a life: Training L.A. law enforcement to understand autism

Kate Movius moved among a roomful of Los Angeles County sheriff’s deputies, passing out a pop trivia quiz and paper prism glasses.

She told them to put on the vision-distorting glasses, and to write with their nondominant hand. As they filled out the tests, Movius moved about the City of Industry classroom pounding abruptly on tables. Then came the cowbell. An aide flashed the overhead lights on and off at random. The goal was to help the deputies understand the feeling of sensory overwhelm, which many autistic people experience when incoming stimulation exceeds their capacity to process.

“So what can you do to assist somebody, or de-escalate somebody, or get information from someone who suffers from a sensory disorder?” Movius asked the rattled crowd afterward. “We can minimize sensory input. … That might be the difference between them being able to stay calm and them taking off.”

Movius, founder of the consultancy Autism Interaction Solutions, is one of a growing number of people around the U.S. working to teach law enforcement agencies to recognize autistic behaviors and ensure that encounters between neurodevelopmentally disabled people and law enforcement end safely.

She and City of Industry Mayor Cory Moss later passed out bags filled with tools donated by the city to aid interactions: a pair of noise-damping headphones to decrease auditory input, a whiteboard, a set of communication cards with words and images to point to, fidget toys to calm and distract.

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“The thing about autistic behavior when it comes to law enforcement is a lot of it may look suspicious, and a lot of it may feel very disrespectful,” said Movius, who is also the parent of an autistic 25-year-old man. Responding officers, she said, “are not coming in thinking, ‘Could this be a developmentally disabled person?’ I would love for them to have that in the back of their minds.”

A sheriff’s deputy reads a pamphlet on autism during the training program.

(Genaro Molina / Los Angeles Times)

Autism spectrum disorder is a developmental condition that manifests differently in nearly every person who has it. Symptoms cluster around difficulties in communication, social interaction and sensory processing.

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An autistic person stopped by police might hold the officer’s gaze intensely or not look at them at all. They may repeat a phrase from a movie, repeat the officer’s question or temporarily lose their ability to speak. They might flee.

All are common involuntary responses for an autistic person in a stressful situation, which a sudden encounter with law enforcement almost invariably is. To someone unfamiliar with the condition, all could be mistaken for intoxication, defiance or guilt.

Autism rates in the U.S. have increased nearly fivefold since the Centers for Disease Control began tracking diagnoses in 2000, a rise experts attribute to broadening diagnostic criteria and better efforts to identify children who have the condition.

The CDC now estimates that 1 in 31 U.S. 8-year-olds is autistic. In California, the rate is closer to 1 in 22 children.

As diverse as the autistic population is, people across the spectrum are more likely to be stopped by law enforcement than neurotypical peers.

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About 15% of all people in the U.S. ages 18 to 24 have been stopped by police at some point in their lives, according to federal data. While the government doesn’t track encounters for disabled people specifically, a separate study found that 20% of autistic people ages 21 to 25 have been stopped, often after a report or officer observation of a person behaving unusually.

Some of these encounters have ended in tragedy.

In 2021, Los Angeles County sheriff’s deputies shot and permanently paralyzed a deaf autistic man after family members called 911 for help getting him to a hospital.

Isaias Cervantes, 25, had become distressed about a shopping trip and started pushing his mother, his family’s attorney said at the time. He resisted as two deputies attempted to handcuff him and one of the deputies shot him, according to a county report.

In 2024, Ryan Gainer’s family called 911 for support when the 15-year-old became agitated. Responding San Bernardino County sheriff‘s deputies shot and killed him outside his Apple Valley home.

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Last year, police in Pocatello, Idaho, shot Victor Perez, 17, through a chain-link fence after the nonspeaking teenager did not heed their shouted commands. He died from his injuries in April.

Autism Interaction Solutions program in the City of Industry.

Sheriff’s deputies take a trivia quiz using their non-writing hands, while wearing vision-distorting glasses, as Kate Movius, standing left, and Industry Mayor Cory Moss, right, ring cowbells. The idea was to help them understand the sensory overwhelm some autistic people experience.

(Genaro Molina / Los Angeles Times)

As early as 2001, the FBI published a bulletin on police officers’ need to adjust their approach when interacting with autistic people.

“Officers should not interpret an autistic individual’s failure to respond to orders or questions as a lack of cooperation or as a reason for increased force,” the bulletin stated. “They also need to recognize that individuals with autism often confess to crimes that they did not commit or may respond to the last choice in a sequence presented in a question.”

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But a review of multiple studies last year by Chapman University researchers found that while up to 60% of officers have been on a call involving an autistic person, only 5% to 40% had received any training on autism.

In response, universities, nonprofits and private consultants across the U.S. have developed curricula for law enforcement on how to recognize autistic behaviors and adapt accordingly.

The primary goal, Movius told deputies at November’s training session, is to slow interactions down to the greatest extent possible. Many autistic people require additional time to process auditory input and verbal responses, particularly in unfamiliar circumstances.

If at all possible, Movius said, wait 20 seconds for a response after asking a question. It may feel unnaturally long, she acknowledged. But every additional question or instruction fired in that time — what’s your name? Did you hear me? Look at me. What’s your name? — just decreases the likelihood that a person struggling to process will be able to respond at all.

Moss’ son, Brayden, then 17, was one of several teenagers and young adults with autism who spoke or wrote statements to be read to the deputies. The diversity of their speech patterns and physical mannerisms showed the breadth of the spectrum. Some were fluently verbal, while others communicated through signs and notes.

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“This population is so diverse. It is so complicated. But if there’s anything that we can show [deputies] in here that will make them stop and think, ‘Hey, what if this is autism?’ … it is saving lives,” Moss said.

Cory Moss and Kate Movius hug

Mayor Cory Moss, left, and Kate Movius hug at the end of the training program last November. Movius started Autism Interaction Solutions after her son was born with profound autism.

(Genaro Molina / Los Angeles Times)

Some disability advocates cautioned that it takes more than isolated training sessions to ensure encounters end safely.

Judy Mark, co-founder and president of the nonprofit Disability Voices United, says she trained thousands of officers on safe autism interactions but stopped after Cervantes’ shooting. She now urges families concerned about an autistic child’s safety to call an ambulance rather than law enforcement.

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“I have significant concern about these training sessions,” Mark said. “People get comfort from it, and the Sheriff’s Department can check the box.”

While not a panacea, supporters argue that a brief course is better than no preparation at all. Some years ago, Movius received a letter from a man whose profoundly autistic son slipped away as the family loaded their car at the beach. He opened the unlocked door of a police vehicle, climbed into the back and began to flail in distress.

Though surprised, the officer seated at the wheel de-escalated the situation and helped the young man find his family, the father wrote to Movius. He had just been to her training.

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