Health
Many Older People Embrace Vaccines. Research Is Proving Them Right.
Kim Beckham, an insurance agent in Victoria, Texas, had seen friends suffer so badly from shingles that she wanted to receive the first approved shingles vaccine as soon as it became available, even if she had to pay for it out of pocket.
Her doctor and several pharmacies turned her down because she was below the recommended age at the time, which was 60. So in 2016, she celebrated her 60th birthday at her local CVS.
“I was there when they opened,” Ms. Beckham recalled. After her Zostavax shot, she said, “I felt really relieved.” She has since received the newer, more effective shingles vaccine, as well as the pneumonia shot, the R.S.V. vaccine, annual flu shots and all recommended Covid vaccinations.
Some older people are really eager to be vaccinated.
Robin Wolaner, 71, a retired publisher in Sausalito, Calif., has been known to badger friends who delay getting recommended shots, sending them relevant medical studies. “I’m sort of hectoring,” she acknowledged.
Deana Hendrickson, 66, who provides daily care for three young grandsons in Los Angeles, sought an additional M.M.R. shot, though she was vaccinated as a child, in case her immunity to measles was waning.
For older adults who express more confidence in vaccine safety than younger groups, the past few months have brought some welcome research. Studies have found important benefits from a newer vaccine and enhanced versions of older ones, and one vaccine may confer a major bonus that nobody had foreseen.
The new studies are coming at a fraught political moment. The nation’s health secretary, Robert F. Kennedy Jr., has long disparaged certain vaccines, calling them unsafe and saying that the government officials who regulate them are compromised and corrupt.
This week, the secretary fired a panel of scientific advisers to the Centers for Disease Control and Prevention, replacing them with some who have been skeptical of vaccines. But so far, Mr. Kennedy has not tried to curb access to the shots for older Americans.
The evidence that vaccines are beneficial remains overwhelming.
The phrase “Vaccines are not just for kids anymore” has become a favorite for Dr. William Schaffner, an infectious disease specialist at Vanderbilt University Medical Center.
“The population over 65, which often suffers the worst impact of respiratory viruses and others, now has the benefit of vaccines that can prevent much of that serious illness,” he said.
Take influenza, which annually sends from 140,000 to 710,000 older people to hospitals and is fatal in 10 percent of them.
For about 15 years, the C.D.C. has approved several enhanced flu vaccines for people over 65. More effective than the standard formulation, they either contain higher levels of the antigen that builds protection against the virus or incorporate an adjuvant that creates a stronger immune response. Or they’re recombinant vaccines, developed through a different method, with higher antigen levels.
In a meta-analysis in the Journal of the American Geriatrics Society, “all the enhanced vaccine products were superior to the standard dose for preventing hospitalizations,” said Rebecca Morgan, a health research methodologist at Case Western Reserve University and an author of the study.
Compared with the standard flu shot, the enhanced vaccines reduced the risk of hospitalization from the flu by 11 to 18 percent in older adults. The C.D.C. advises adults over 65 to receive the enhanced vaccines, as many already do.
More good news: Vaccines to prevent respiratory syncytial virus (R.S.V.) in people over 60 are performing admirably.
R.S.V. is the most common cause of hospitalization for infants, and it also poses significant risks to older people. “Season in and season out,” Dr. Schaffner said, “it produces outbreaks of serious respiratory illness that rivals influenza.”
Because the Food and Drug Administration first approved an R.S.V. vaccine in 2023, the 2023-24 season provided “the first opportunity to see it in a real-world context,” said Dr. Pauline Terebuh, an epidemiologist at Case Western Reserve School of Medicine and an author of a recent study in the journal JAMA Network Open.
In analyzing electronic health records for almost 800,000 patients, the researchers found the vaccines to be 75 percent effective against acute infection, meaning illness that was serious enough to send a patient to a health care provider.
The vaccines were 75 percent effective in preventing emergency room or urgent care visits, and 75 percent effective against hospitalization, both among those aged 60 to 74 and those older.
Immunocompromised patients, despite having a somewhat lower level of protection from the vaccine, will also benefit from it, Dr. Terebuh said. As for adverse effects, the study found a very low risk for Guillain-Barré syndrome, a rare condition that causes muscle weakness and that typically follows an infection, in about 11 cases per one million doses of vaccine. That, she said, “shouldn’t dissuade people.”
The C.D.C. now recommends R.S.V. vaccination for people 75 and older, and for those 60 to 74 if they’re at higher risk of severe illness (from heart disease, say).
As data from the 2024-25 season becomes available, researchers hope to determine if the vaccine will remain a one-and-done, or whether immunity will require repeated vaccination.
People over 65 express the greatest confidence in vaccine safety of any adult group, a KFF survey found in April. More than 80 percent said they were “very “or “somewhat confident” about M.M.R., shingles, pneumonia and flu shots.
Although the Covid vaccine drew lower support among all adults, more than two-thirds of older adults expressed confidence in its safety.
Even skeptics might become excited about one possible benefit of the shingles vaccine: This spring, Stanford researchers reported that over seven years, vaccination against shingles reduced the risk of dementia by 20 percent, a finding that made headlines.
Biases often undermine observational studies that compare vaccinated with unvaccinated groups. “People who are healthier and more health-motivated are the ones who get vaccinated,” said Dr. Pascal Geldsetzer, an epidemiologist at the Knight Initiative for Brain Resilience at Stanford and lead author of the study.
“It’s hard to know whether this is cause and effect,” he said, “or whether they’re less likely to develop dementia anyway.”
So the Stanford team took advantage of a “natural experiment” when the first shingles vaccine, Zostavax, was introduced in Wales. Health officials set a strict age cutoff: People who turned 80 on or before Sept. 1, 2013, weren’t eligible for vaccination, but those even slightly younger were eligible.
In the sample of nearly 300,000 adults whose birthdays fell close to either side of that date, almost half of the eligible group received the vaccine, but virtually nobody in the older group did.
“Just as in a randomized trial, these comparison groups should be similar in every way,” Dr. Geldsetzer explained. A substantial reduction in dementia diagnoses in the vaccine-eligible group, with a much stronger protective effect in women, therefore constitutes “more powerful and convincing evidence,” he said.
The team also found reduced rates of dementia after shingles vaccine was introduced in Australia and other countries. “We keep seeing this in one data set after another,” Dr. Geldsetzer said.
In the United States, where a more potent vaccine, Shingrix, became available in 2017 and supplanted Zostavax, Oxford investigators found an even stronger effect.
By matching almost 104,000 older Americans who received a first dose of the new vaccine (full immunization requires two) with a group that had received the earlier formulation, they found delayed onset of dementia in the Shingrix group.
How a shingles vaccine might reduce dementia remains unexplained. Scientists have suggested that viruses themselves may contribute to dementia, so suppressing them could protect the brain. Perhaps the vaccine revs up the immune system in general or affects inflammation.
“I don’t think anybody knows,” said Dr. Paul Harrison, a psychiatrist at Oxford and a senior author of the study. But, he added, “I’m now convinced there’s something real here.”
Shingrix, now recommended for adults over 50, is 90 percent effective in preventing shingles and the lingering nerve pain that can result. In 2021, however, only 41 percent of older Americans had received one dose of either shingles vaccine.
A connection to dementia will require further research, and Dr. Geldsetzer is trying to raise philanthropic funding for a clinical trial.
And “if you needed another reason to get this vaccine,” Dr. Schaffner said, “here it is.”
Health
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Health
Popular weight-loss drugs linked to unexpected male fertility benefit
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Taking a GLP-1 medication for weight loss may improve male fertility, according to experts.
Research presented this week at ENDO 2026, the Endocrine Society’s annual meeting in Chicago, explored how obesity is strongly linked to fertility problems in men.
Excess weight can contribute to dysregulation of the hypothalamic-pituitary-gonadal (HPG) axis — the hormone system that regulates testosterone production — and functional hypogonadism, a condition in which testosterone levels are abnormally low because of disrupted hormone signaling. These changes can also impair semen quality.
WEIGHT-LOSS MEDICATIONS COULD IMPACT SEXUAL HEALTH IN UNEXPECTED WAYS
The researchers evaluated how GLP-1 weight-loss drugs impact reproductive hormones and metabolic outcomes, analyzing data of men between the ages of 18 and 65 who were taking one of the medications, according to a press release.
The systematic review of five randomized controlled trials focused on measuring testosterone, brain hormones involved in testosterone and sperm production, and a protein that carries sex hormones in the blood. Semen quality, weight and BMI, cholesterol and blood sugar were also measured.
Men with obesity and low testosterone linked to obesity may experience improved testosterone, sperm quality and metabolic heath while taking a GLP-1, the study found. (iStock)
The results suggested that GLP-1 medications do not suppress male hormones. Men with obesity and low testosterone linked to obesity may experience improved testosterone, sperm quality and metabolic health, especially during weight loss.
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In one four-week study, dulaglutide showed no significant changes in reproductive hormones or sexual function.
In a separate 16-week trial, liraglutide improved hormones in obese men with functional hypogonadism, meaning low testosterone was likely related to obesity. The review found that liraglutide was better for health outcomes than hormone replacement therapy.
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Another liraglutide study reported improved sperm concentration and count.
The study authors concluded that GLP-1s “do not appear to acutely suppress the male HPG axis and may improve reproductive hormones and semen parameters in obese hypogonadal men, largely within the context of weight loss.” (iStock)
A 24-week trial of semaglutide, known commercially as Ozempic and Wegovy, saw improvement in sperm shape and bad cholesterol, while preserving total testosterone.
As only five trials were included, the small evidence base suggests more research is necessary to prove further association.
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In an abstract of the research, the authors summed up that GLP-1s “do not appear to acutely suppress the male HPG axis and may improve reproductive hormones and semen parameters in obese hypogonadal men, largely within the context of weight loss.”
“However, evidence remains limited and heterogeneous, underscoring the need for larger RCTs explicitly powered to assess male reproductive outcomes,” they wrote.
“This provides early evidence that GLP-1 medications taken by obese men with hypogonadism/low testosterone (low T) improves testosterone levels,” one doctor said. (iStock)
Dr. Anthony Puopolo, men’s health expert and lead medical provider for RexMD, reflected on these findings in an interview with Fox News Digital.
“This provides early evidence that GLP-1 medications taken by obese men with hypogonadism/low testosterone (low T) improves testosterone levels,” he said.
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While more research is necessary, Pupolo, who was not involved in the study, shared his optimism about how GLP-1s can play a role in improving male fertility.
“If this finding continues to gain evidence, GLP-1s might be a better option for low T than testosterone replacement therapy (TRT) in obese men – as GLP-1 medications preserve fertility, whereas TRT tends to be harmful to male reproductive/sperm function,” he added.
Health
Measles-infected traveler may have exposed passengers at LAX and nearby hotel, health officials warn
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A traveler infected with measles may have exposed passengers at Los Angeles International Airport and guests at a nearby hotel after arriving in Los Angeles County earlier this month, health officials said Wednesday.
The Los Angeles County Department of Public Health said it is investigating a confirmed measles case involving a traveler who arrived aboard Cathay Pacific Flight CX 884 on June 11. The traveler was infectious while passing through Los Angeles County, potentially exposing others at LAX and the Hilton Los Angeles Airport Hotel.
The case marks the sixth measles infection reported in Los Angeles County this year. Health officials said the risk of exposure could increase as summer travel ramps up and Los Angeles welcomes international visitors for FIFA World Cup events being held in the region.
MEASLES CASES CONFIRMED AT FOUR MAJOR US AIRPORTS ACROSS COUNTRY AMID PEAK HOLIDAY TRAVEL
A 3D illustration shows measles virus particles. (iStock)
According to health officials, anyone who was at the Tom Bradley International Terminal between 10 a.m. and noon on June 11 may have been exposed. Officials also identified a potential exposure at the Hilton Los Angeles Airport Hotel, located at 5711 W. Century Blvd., between 11:15 a.m. and 12:15 p.m. that same day.
The Centers for Disease Control and Prevention is working with local health departments to notify passengers who were seated near the infected traveler on the international flight.
People who were at either location during the listed times could develop symptoms between seven and 21 days after exposure, officials said. The last day to monitor for symptoms is July 2.
AT LEAST 46 CHILDREN DEAD AMID MEASLES OUTBREAK AS VIRUS SPREADS GLOBALLY
Los Angeles International Airport is seen in Los Angeles, California. Health officials said a traveler infected with measles may have exposed passengers at LAX on June 11. (Michael Yanow/NurPhoto)
“As measles cases increase, it is important that residents take steps to make sure they are fully protected,” Los Angeles County Health Officer Dr. Muntu Davis said. “The MMR vaccine is the safest and most reliable way to prevent measles and protect yourself, your family, and your community.”
Travelers exit a terminal at Los Angeles International Airport in Los Angeles on Monday, March 23, 2026. (Ethan Swope/AP Photo)
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Symptoms include fever, cough, runny nose, red and watery eyes, followed by a rash that typically begins on the face before spreading to the rest of the body.
Fox News Digital reached out to the Los Angeles County Department of Public Health for additional comment but did not receive a response.
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