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A “yoga pill” to end anxiety? Neuroscientists discover a brain circuit that instantly deflates stress

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A “yoga pill” to end anxiety? Neuroscientists discover a brain circuit that instantly deflates stress

Your heart is racing, your arms are tingling and your breathing is shallow. You’re having an anxiety attack. And you’re in a public place, to boot. A crowded restaurant, say, or at the office. Not a space where you can comfortably lay on the ground and do some deep breathing exercises to calm yourself.

What if there were a pill that would instead induce that kind of calm breathing for you? That scenario might be possible after a new scientific breakthrough.

Neuroscientists at the Salk Institute for Biological Studies in La Jolla have identified a brain pathway that instantly deflates anxiety. The new study, which published earlier this week in the scientific journal Nature Neuroscience, lays out how the aforementioned brain circuit regulates voluntary breathing — meaning conscious breathing as opposed to automatic breathing that happens without your having to think about it — allowing us to slow our breath and calm our mind.

The discovery opens up the potential for the creation of new drugs that would mimic the relaxed state common during breath work, meditation or yoga. Sung Han, senior author of the study, says he’d like to one day see a “yoga pill,” as he calls it, on the market to ease anxiety. It would likely be useful for the more than 40 million adults in the U.S, who, according to the National Alliance on Mental Illness, suffer from an anxiety disorder.

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Han says the new discovery is a real scientific breakthrough.

“As a scientist, finding something never known before is always exciting,” he told the Los Angeles Times. “This top-down breathing circuit has been a longstanding question in the neuroscience field. It’s exciting to find the neural mechanism to explain how the slowing down of breathing can control negative emotions, like anxiety and fear.”

We’ve long known that we can control our breathing patterns to alter our state of mind — when we get stressed, we might take a deep, slow breath to feel calmer. But scientists didn’t understand how that worked — which parts of the brain were actually slowing our breath and why that activity makes us calmer. Now they know that there is a group of cells in the cortex, the higher part of the brain responsible for more conscious, complex thought, that send messages to the brain stem, which in turn sends information to the lungs. That’s the aforementioned “circuit.”

The discovery validates soothing behavioral practices such as yoga, mindfulness and even “box breathing” — the latter a technique that involves repeatedly breathing in, then holding your breath, for four-second counts in order to relieve stress — because it grounds these behavioral practices in science.

But the practical applications is what makes the Salk discovery so important, Han says.

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“It can, potentially, create a whole new class of drugs that can more specifically target anxiety disorder,” he says.

These would differ from common anti-anxiety medications by more specifically targeting areas of the brain. Common anti-anxiety drugs like Xanax and Lexapro target multiple areas of the brain that control multiple brain processes and behaviors. It’s why these drugs don’t work for everyone in the same way and may create unwanted side effects. More precisely targeting an individual brain circuit makes a medication more effective and reduces potential side effects. And, in extreme cases, such a pill might be more efficient for targeting anxiety than doing breathing exercises.

“If you’re in panic, breathing techniques alone may not be sufficient to suppress anxiety,” Han says.

Han’s team is now trying to find the opposite circuit — a fast breathing circuit — that increases anxiety.

“To target the slow breathing circuit, we need to understand the opposite circuit, so we can avoid targeting it,” Han says. “To relieve the anxiety.”

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While Han hopes his findings will lead to a “yoga pill,” that’s likely a long ways off. The research, and ensuing clinical trials, could take as much as 10 years, he says. And nothing is for certain.

“I cannot say that this discovery is directly connected to the discovery of the new medication,” Han says. “But I can say it’s a stepping stone. We now know the pathway. That’s exciting. That is the first step.”

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Video: NASA Announces Artemis III Crew

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Video: NASA Announces Artemis III Crew

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NASA Announces Artemis III Crew

NASA announced the crew of Artemis III mission, which will fly to low-Earth orbit to test rendezvous and docking maneuvers with one or two lunar landers.

“I am excited to welcome you as the next crew in the Artemis journey to successfully return to the moon — this time to stay.” “I’m honored by the role that I’ve been given. I’m also very humbled by the task in front of us. But first and foremost, I’m grateful.” “So with that, the Artemis II crew, comrade, hands you the baton. You got the controls.” “As you know, we had a significant anomaly at our Launch Complex 36A on May 28. We’ve redoubled our efforts and are moving forward.”

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NASA announced the crew of Artemis III mission, which will fly to low-Earth orbit to test rendezvous and docking maneuvers with one or two lunar landers.

By Alisa Shodiyev Kaff

June 9, 2026

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Santa Monica Mountains’ last steelhead trout survived the Palisades fire — and even had babies

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Santa Monica Mountains’ last steelhead trout survived the Palisades fire — and even had babies

Scientists feared the Santa Monica Mountains’ last remaining steelhead trout were dead, smothered by debris flows unleashed by the Palisades fire.

But the endangered fish surprised them: A team of biologists recently spotted 30 of the rare trout — and 21 babies — in Topanga Creek.

“There was a lot of happy dancing in the creek,” said Rosi Dagit, principal conservation biologist for the Resource Conservation District of the Santa Monica Mountains, which works with public and private landowners to conserve natural resources.

That’s because the steelhead here are endangered, at both the state and federal levels. Once, they swam in most streams of the Santa Monicas, but their numbers plummeted amid overfishing and coastal development. Increasingly frequent wildfire has further stressed their habitat. Topanga Creek, a biodiversity hot spot, is home to their last known population in the mountains that stretch from the Hollywood Hills to Point Mugu in Ventura County.

The trout that were spotted, including this one, are part of a distinct Southern California population that’s listed as endangered at the state and federal levels.

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(RCDSMM Stream Team)

The California Department of Fish and Wildlife spearheaded a complex mission to rescue trout threatened by the Palisades fire that sparked in January 2025.

Time was of the essence. The fire hadn’t yet been fully contained. But rain was on the way, which would sweep massive amounts of sediment from the denuded hillsides into the water. Fish are often killed this way.

Crews stunned the fish with electricity, scooped them up in buckets, trucked them to a hatchery and ultimately moved them to Arroyo Hondo Creek in Santa Barbara County.

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Within days, Topanga Creek was choked with mud. Some assumed the fish left behind were goners.

But in March, the conservation district’s team found four. The following month, when water conditions were clearer, they saw more.

“These fish continue to amaze me,” said Kyle Evans, environmental program manager for the state Department of Fish and Wildlife, who had seen the damage to the creek. “I had seen populations get wiped out in similar situations. So when I heard, I was thrilled.”

Evans surmises the fish that survived were in an area of the creek where less charred material and sediment were swept in.

“These fish likely hunkered down, were hiding under some rocks or places to try to get away from the main concentration of flow,” he said. “And luckily they weren’t buried.”

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The ones that were spotted were fairly small, around 6 to 14 inches. Rainbow trout and steelhead trout are the same species, but with different lifestyles. If the fish remain in freshwater, they’ll be considered rainbows. However, they can migrate to the ocean and become steelhead, where they typically grow larger before returning to their natal waters to spawn.

Topanga Creek hasn’t fully recovered from the damage it sustained, but scientists say it’s looking better. Surveys last year were “so depressing,” Dagit said, with very few animals, and stretches that were essentially transformed into flat roads from all the sediment buildup. Some of the riparian canopy burned right down to the creek.

Then came 32 inches of rain over the last nine months, scouring out and moving sediment, creating deeper pools. Dagit said they recently found newt egg masses for the first time in years, as well as a few adult newts and many frogs. Plants that provide cover are starting to recover.

She provided photos comparing certain pools last year and this year, some dramatically transformed. In September 2025, the Shrine Pool could have been an overgrown hiking trail. This April, it was filled with shallow water.

Shrine Pool, Sept. 2025, left, and the same location, April 2026, right.

The Shrine Pool in September 2025, left, and the same location in April 2026, right, with RCDSMM’s Isaac Yelchin donning a wetsuit.

(RCDSMM Stream Team)

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Topanga Creek is home to another endangered fish, the small but hardy northern tidewater goby, often described as cute. Not long before the trout operation, Dagit led a rescue of hundreds of these fish too. Many were repatriated to the lagoon at the mouth of the creek in a moving ceremony last June.

There’s still the matter of what to do with the trout that were moved to Santa Barbara County last year. Evans would like to bring them home to the Santa Monicas at some point, but isn’t sure if it will happen. On one hand, they could bolster the small, genetically isolated surviving population. On the other, they might inadvertently bring in a disease or bacteria. There is some time to decide. Evans estimates the creek still needs to recover for two to three more years.

For now, the fish are functioning fine in their adopted creek. Experts worried the trauma wrought by the move would disrupt their spawning process, but they had babies that spring. This year, they spawned again.

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Pacifica pier cracks, another coastal casualty as seas continue to rise

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Pacifica pier cracks, another coastal casualty as seas continue to rise

The Pacifica Municipal Pier was shut down and taped off Thursday after city workers noticed cracks running through the landmark structure and concrete chunks falling into the ocean.

It’s just one of many coastal California structures that have recently crumbled under pressure from a rising and relentless ocean.

Officials from the small, beach city south of San Francisco said the pier was closed due to “cracking, separation, and displacement of the concrete walkway and structural elements.”

It will stay closed while structural engineers asses its safety.

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Photos taken by city employees show a wide crack that runs from top to bottom and across the structure as well. Other photos show a large horizontal crack under the foundation of a small restaurant on the pier, the Chit Chat Cafe.

The cafe was also shut down.

This is not the first time the 53-year-old pier has shown signs of stress. In 2021, part of it was shut down after handrails along the edge collapsed. And in 2023, after a series of storms pummeled the Central California coast, damaging parts of the pier, the structure was partially closed for more than year.

Those same storms caused extensive damage in Aptos and Capitola, 70 miles south, where piers and waterfront infrastructure were swept away or damaged.

In 2024, a 150- to 180- foot section of the Santa Cruz wharf was ripped off by powerful waves.

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At least 10 of the state’s dozens of coastal public piers were closed for part or all of 2024 due to structural damage sustained in winter storms since 2022. At least five others have longer-term upgrades planned to address structural issues.

“These things are costly to maintain,” said Zach Plopper, senior environmental director at Surfrider. “They are a part of our California coastal culture in many ways, but we’re going to need to reckon with, one, the state that they’re in, and two, the continuous and worsening threats they’re going to experience,”

He said most of the piers were constructed in the early 1900s, and they weren’t built to withstand decades of rough seas, storms and rising sea level.

“With this incoming El Niño, which is forecasted to be significant, and this marine heat wave we’re in the midst of, we’re kind of in uncharted waters as far as what this winter could bring in terms of storms and swells to the California coast, and we’re likely going to see a lot more damage,” he said. “Not just piers, but roads and other coastal infrastructure up and down the state.”

There was no storm in Pacifica earlier this week, so no single event could be blamed for the destruction.

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However, a 2025 report from an outside engineering firm, GHD, found that several sections of the pier were in “poor” or “serious” condition, and they recommended closure before anticipated storms or events that could “subject the piles to high winds, swells and large waves.”

The firm found several areas of the pier where concrete was missing and rebar was exposed and corroding.

“The pier has continued to experience high winds and large waves in a harsh marine environment,” the engineers wrote in the report, noting that continuous exposure to seawater or marine spray was “detrimental” to the structure.

A 2023 city report estimated it would cost $19 million to repair.

That same year, a state law was enacted to require local governments along the California coast to plan for sea level rise in the coming decades.

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Sea level has risen some 8 inches, on average, along the coast in the past 150 years, Plopper said, and researchers anticipate another foot in the next 25 years.

“We’re going to see profound shifts on our coastline, none that we have ever experienced before, and building static structures on the coast just doesn’t work all that well,” he said. “We’re going to have to make some really hard decisions.”

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