Health
‘Sleep disorder drove my son to suicide,’ New York mother says: ‘Broke my heart’
This story discusses suicide. If you or someone you know is having thoughts of suicide, please contact the Suicide & Crisis Lifeline at 988 or 1-800-273-TALK (8255).
Chronic lack of sleep can cause a long list of physical and mental issues — and for one young man, his mother believes it led to his death.
Derek McFadden was just 23 when he took his own life on Aug. 17, 2018, in Tucson, Arizona.
His mother, Robin McFadden, who lives in Tuxedo Park, New York, said she believes her son’s insomnia was the “only driver” of his suicide.
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Derek McFadden was an “extremely funny kid” who loved swimming, snow-skiing and cuddling, his mother said — but for most of his life, he struggled with debilitating insomnia.
At around 8 years old, he started taking small doses of sleeping medication, which helped for several years.
Derek McFadden, pictured at left with his mom Robin McFadden, was 23 when he took his own life on Aug, 17, 2018, in Tucson, Arizona. (Robin McFadden)
Around the time he turned 18, during his senior year of high school, the medication stopped working, McFadden said.
“He never got a good night’s sleep, but he soldiered through his school day and then would come home and lie down on his bed, exhausted, but couldn’t fall asleep,” she told Fox News Digital in an interview.
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McFadden took her son to multiple doctors and they tried different medications — none of which worked, she said.
“Derek would just lie there at night, and he was so tired, but he couldn’t fall sleep,” she said.
Amid the sleep struggles, her son managed to graduate from high school — but things got even worse when he left for college at the University of Arizona.
Derek McFadden, left, is pictured with his older brother Jake McFadden. (Robin McFadden)
He’d chosen Arizona because he was an “avid outdoorsman” who loved fly-fishing, going off-roading in his Jeep and spending time with his dog, which he’d adopted for emotional support.
“Our hope was that with Derek being in Arizona, the sunshine during the day would stimulate his brain to wake up so he could go to sleep at night, but it just didn’t work,” McFadden said.
The doctor’s visits continued, but none of the experts could figure out what was causing the insomnia.
“There was something wrong in his brain that was preventing him from sleeping.”
“Every doctor would assume it was sleep hygiene, and that he was doing something wrong,” McFadden said.
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“They assumed that because he was 18, 19 or 20 years old that he was playing video games all night.”
She added, “But Derek knew sleep hygiene. He had done so much research on his own. There was something wrong in his brain that was preventing him from sleeping.”
Derek McFadden, far left, is pictured with his brother, mother and father. (Robin McFadden)
The family looked into holistic approaches, including hypnosis, acupuncture and “brain training,” but “nothing seemed to work,” McFadden said.
Many nights, he would go the entire night without sleeping — sometimes up to three days in a row, she said.
“It was really, really bad,” McFadden said.
Physical and mental toll
As the months went by and sleep continued to elude her son, McFadden said it began to take a toll on his immune system.
After consecutive nights without sleeping, he developed bruises all around his eyes.
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“Derek was constantly getting sick, and that made him feel like he was not a normal kid,” she said. “He just couldn’t fight anything off. He was always at Urgent Care.”
Her son developed severe acid reflux and stomach pain, to the point where it became difficult for him to eat.
“Sometimes his insomnia got so severe that he couldn’t keep any food or fluids down at all,” McFadden said.
Multiple times, he ended up in the emergency room with dehydration and severe cramping, she said.
Derek was an “avid outdoorsman” who loved fly-fishing, going off-roading in his Jeep and spending time with his dog, which he’d adopted for emotional support, his mother said. (Robin McFadden)
The lack of sleep also changed her son’s demeanor and personality, McFadden said.
“Derek had tremendous mood swings — he became anxiety-ridden and depressed,” she recalled.
“He would have hallucinations, and was constantly losing things. He couldn’t think clearly.”
On the rare occasion that her son had a good night’s sleep, McFadden said, he was “a completely different person, as happy as could be.”
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“It broke my heart, because he was such a happy, funny, huge-hearted person, and it was really sad to watch his decline.”
Unable to keep up with his studies, her son had to drop out of college.
“He couldn’t even hold a job because he couldn’t sleep at night,” McFadden said.
“He saw there was no cure, no future, and he just didn’t see a point in going on.”
In July 2018, when her son came home from Tucson for the summer, McFadden knew something had shifted.
“We were sitting on the sofa and he said to me, ‘Mom, I’m gonna die young,’” she recalled.
“And I said, ‘Derek, why do you say that?’ And he said, ‘Because my mind and body can’t take the sleep deprivation.’”
Derek McFadden, left, is pictured with his older brother. After the tragedy, his mother said she realized her son had likely been planning his suicide in recent weeks. (Robin McFadden)
Her son had also expressed that he didn’t want to have children because he didn’t want to pass on the disorder, McFadden said.
“He saw there was no cure, no future, and he just didn’t see a point in going on,” she said. “Physically, he was starting to fall apart, and mentally, his cognitive ability was going.”
“Physically, he was starting to fall apart.”
Four weeks later, McFadden got an early-morning call from the Tucson Police Department notifying her that her son had taken his life.
After the tragedy, McFadden realized that her son had likely been planning his suicide in recent weeks.
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“He had contacted some old friends, and in his text messages and phone calls, he sounded very serene, relieved and calm,” she recalled. “I truly believe Derek had made the decision. He just saw no future for himself.”
The sleep-suicide link
Studies have suggested a likely connection between sleep and suicide.
Research published in the journal Current Psychiatry Reports found that treating insomnia and nightmares, or addressing the source of those issues, could help prevent “the rising threat of suicide.”
“Sleep is crucial for emotional and psychological balance.”
Dr. Brett Osborn, a Florida neurologist and longevity expert with the firm Senolytix, said there is a “significant body of research” suggesting a link between sleep deprivation and an increased risk of suicide.
“Sleep is crucial for emotional and psychological balance,” he told Fox News Digital in an interview.
“Lack of sleep can lead to mood disturbances, irritability and decreased stress tolerance, all of which can worsen feelings of despair or depression — potentially leading to suicidal thoughts.”
On the rare occasion that her son had a good night’s sleep, McFadden said, he was “a completely different person, as happy as could be.” Derek McFadden is pictured here with his mother, Robin McFadden. (Robin McFadden)
Sleep deprivation can also affect cognitive functions, the doctor continued.
“This impairment can make it harder for individuals to see alternative solutions to problems or seek help, potentially increasing the risk of suicidal behavior,” he said.
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Sleep problems are also commonly associated with psychiatric disorders, such as depression and anxiety, which are themselves significant risk factors for suicide, according to Osborn.
“Sleep pathology is extremely complex and challenging, because sleep itself is poorly understood.”
“Insomnia and disrupted sleep patterns are particularly prevalent in these conditions,” he warned. “This can be a source of diagnostic confusion and resultant treatment errors.”
Sleep also affects various biological processes, Osborn noted — “including the regulation of neurotransmitters like serotonin (which is involved in mood regulation) and stress hormones like cortisol.”
Derek McFadden was an “extremely funny kid” who loved swimming, snow-skiing and cuddling, his mother said. (Robin McFadden)
“Chronic sleep deprivation may lead to dysregulation in these systems, which could contribute to depressive symptoms and suicidal ideation.”
While the majority of insomnia patients respond to lifestyle changes and/or medications, Osborn noted, there is a subset of patients who are “more difficult to manage.”
“Often, there are underlying medical problems, like reflux, that fly under the radar and predispose the individual to insomnia,” he told Fox News Digital.
Derek McFadden, center, in cap and gown, is pictured with his family at his high-school graduation. (Robin McFadden)
“Another issue is the potentially reciprocal relationship between depression and anxiety,” Osborn said.
“Sleep pathology is extremely complex and challenging, because sleep itself is poorly understood,” he continued. “A multimodal, interdisciplinary approach — involving a psychiatrist and a sleep specialist — is always best.”
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Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, agreed that there is a proven link between insomnia, stress, anxiety and depression.
“Since suicide is a manifestation of severe depression, I think there is a link there, too, though insomnia wouldn’t be the entire cause,” he told Fox News Digital.
Fly-fishing was one of Derek McFadden’s favorite hobbies. (Robin McFadden)
Siegel refers to it as a “cycle of worry.”
“Anxiety interferes with sleep, which then makes you more anxious and more sleepless, especially if you add caffeine to combat the grogginess,” he said.
During sleep, the brain relaxes and “cleanses” itself, Siegel said.
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“Waking up refreshed can improve mood, especially when accompanied by exercise,” he noted.
For those with severe insomnia, Siegel recommends undergoing a full sleep study/evaluation — typically with an EEG or video monitoring — to help determine the causes.
“Severe, resistant cases require evaluations by sleep specialists, neurologists and psychiatrists,” he added.
Call for awareness
The most “disheartening” part of her son’s tragedy, according to McFadden, was a lack of support from the health community, in her view.
“Other than sleep apnea and bad sleep hygiene, the medical community does not seem to believe that severe insomnia really exists,” she told Fox News Digital.
“And that just infuriates me.”
Today, McFadden’s goal is to raise awareness of chronic insomnia — “because there are so many people in this world who are suffering from this.”
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Health
Ancient plague mystery cracked after DNA found in 4,000-year-old animal remains
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Long before the Black Death killed millions across Europe in the Middle Ages, an earlier, more elusive version of the plague spread across much of Eurasia.
For years, scientists were unsure how the ancient disease managed to spread so widely during the Bronze Age, which lasted from roughly 3300 to 1200 B.C., and stick around for nearly 2,000 years, especially since it wasn’t spread by fleas like later plagues. Now, researchers say a surprising clue may help explain it, a domesticated sheep that lived more than 4,000 years ago.
Researchers found DNA from the plague bacterium Yersinia pestis in the tooth of a Bronze Age sheep discovered in what is now southern Russia, according to a study recently published in the journal Cell. It is the first known evidence that the ancient plague infected animals, not just people, and offers a missing clue about how the disease spread.
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“It was alarm bells for my team,” study co-author Taylor Hermes, a University of Arkansas archaeologist who studies ancient livestock and disease spread, said in a statement. “This was the first time we had recovered the genome from Yersinia pestis in a non-human sample.”
A domesticated sheep, likely similar to this one, lived alongside humans during the Bronze Age. (iStock)
And it was a lucky discovery, according to the researchers.
“When we test livestock DNA in ancient samples, we get a complex genetic soup of contamination,” Hermes said. “This is a large barrier … but it also gives us an opportunity to look for pathogens that infected herds and their handlers.”
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The highly technical and time-consuming work requires researchers to separate tiny, damaged fragments of ancient DNA from contamination left by soil, microbes and even modern humans. The DNA they recover from ancient animals is often broken into tiny pieces sometimes just 50 “letters” long, compared to a full human DNA strand, which contains more than 3 billion of those letters.
Animal remains are especially tough to study because they are often poorly preserved compared to human remains that were carefully buried, the researchers noted.
The finding sheds light on how the plague likely spread through close contact between people, livestock and wild animals as Bronze Age societies began keeping larger herds and traveling farther with horses. The Bronze Age saw more widespread use of bronze tools, large-scale animal herding and increased travel, conditions that may have made it easier for diseases to move between animals and humans.
When the plague returned in the Middle Ages during the 1300s, known as the Black Death, it killed an estimated one-third of Europe’s population.
The discovery was made at Arkaim, a fortified Bronze Age settlement in the Southern Ural Mountains of present-day Russia near the Kazakhstan border. (iStock)
“It had to be more than people moving,” Hermes said. “Our plague sheep gave us a breakthrough. We now see it as a dynamic between people, livestock and some still unidentified ‘natural reservoir’ for it.”
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Researchers believe sheep likely picked up the bacteria from another animal, like rodents or migratory birds, that carried it without getting sick and then passed it to humans. They say the findings highlight how many deadly diseases begin in animals and jump to humans, a risk that continues today as people move into new environments and interact more closely with wildlife and livestock.
“It’s important to have a greater respect for the forces of nature,” Hermes said.
The study is based on a single ancient sheep genome, which limits how much scientists can conclude, they noted, and more samples are needed to fully understand the spread.
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The researchers plan to study more ancient human and animal remains from the region to determine how widespread the plague was and which species may have played a role in spreading it.
Researchers (not pictured) found plague-causing Yersinia pestis DNA in the remains of a Bronze Age sheep. (iStock)
They also hope to identify the wild animal that originally carried the bacteria and better understand how human movement and livestock herding helped the disease travel across vast distances, insights that could help them better anticipate how animal-borne diseases continue to emerge.
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The research was led by scientists at the Max Planck Institute for Infection Biology, with senior authors Felix M. Key of the Max Planck Institute for Infection Biology and Christina Warinner of Harvard University and the Max Planck Institute for Geoanthropology.
The research was supported by the Max Planck Society, which has also funded follow-up work in the region.
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Aging-related joint disorder increasingly affects people under 40, study finds
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Cases of gout are rising in younger individuals, according to a global study.
The condition, which is a type of inflammatory arthritis, steadily increased in people aged 15 to 39 between 1990 and 2021, researchers in China announced.
Although rates vary widely between countries, the total number of young people with the condition is expected to continue rising through 2035.
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The study, published in the journal Joint Bone Spine, investigated 2021 data from the Global Burden of Disease (GBD), spanning 204 countries within the 30-year timeframe.
The data measured gout prevalence, incidence and years lived with disability, tracking global trends over time. The results showed a global increase across all three outcomes.
Gout is expected to continue rising in young people through 2035. (iStock)
Prevalence and disability years increased by 66%, and incidence rose by 62%. In 2021, 15- to 39-year-olds accounted for nearly 14% of new gout cases globally, the study found.
Men from 35 to 39 years old and people in high-income regions had the highest burden, but high-income North America topped the list for highest rates.
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Men were also found to have lived more years with gout due to high BMI, while women tended to have the condition as a link to kidney dysfunction, the study noted.
The total number of cases is expected to increase globally due to population growth, but the study projected that rates per population would decrease.
The researchers noted that data quality, especially in low-income settings, could have posed a limitation to the broad GBD data.
What is gout?
Gout is a common form of arthritis involving sudden and severe attacks of pain, swelling, redness and tenderness in the joints, according to Mayo Clinic. It most often occurs in the big toe.
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The condition occurs when urate crystals accumulate in the joint. These form when there are high levels of uric acid in the blood, which the body produces when it breaks down a natural substance called purines.
A gout flare-up can happen at any time, often at night, causing the affected joint to feel hot, swollen, tender and sensitive to the touch.
Urate crystals, described as sharp and needle-like, build up in the joint, causing intense pain and swelling. (iStock)
Purines can also be found in certain foods, like red meat or organ meats like liver and some seafood, including anchovies, sardines, mussels, scallops, trout and tuna, according to the Mayo Clinic. Alcoholic drinks, especially beer, and drinks sweetened with fruit sugar can also lead to higher uric acid levels.
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Uric acid will typically dissolve in the blood and pass through the kidneys into urine, but when the body produces too much or too little uric acid, it can cause a build-up of urate crystals. These are described by the Mayo Clinic as sharp and needle-like, causing pain, inflammation and swelling in the joint or surrounding tissue.
Risk factors for gout include a diet rich in high-purine foods and being overweight, which causes the body to produce more uric acid and the kidneys to have trouble eliminating it.
Experts urge patients to seek medical attention for gout flare-ups. (iStock)
Certain conditions like untreated high blood pressure, diabetes, obesity, metabolic syndrome and heart and kidney diseases can increase the risk of gout, as well as certain medications.
A family history of gout can also increase risk. Men are more likely to develop the condition, as women tend to have lower uric acid levels, although symptoms generally develop after menopause.
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Untreated gout can cause worsening pain and joint damage, experts caution. It may also lead to more severe conditions, such as recurrent gout, advanced gout and kidney stones.
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The Mayo Clinic advises patients to seek immediate medical care if a fever occurs or if a joint becomes hot and inflamed, which is a sign of infection. Certain anti-inflammatory medications can help treat gout flares and complications.
Fox News Digital reached out to the researchers for comment.
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