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Sickle cell patient offers hope to Ugandan community where disease is prevalent

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Sickle cell patient offers hope to Ugandan community where disease is prevalent
  • Barbara Nabulo, a sickle cell disease patient, has emerged as a dedicated advocate for others facing the same condition in rural Uganda.
  • Despite her own challenges with the disease, Nabulo serves as a counselor to fellow patients, offering them encouragement and hope.
  • Nabulo regularly visits sickle cell patients in the hospital ward, providing them with guidance and reassurance.

Barbara Nabulo was one of three girls in her family. But when a sister died, her mother wailed at the funeral that she was left with just one and a half daughters.

The half was the ailing Nabulo, who at age 12 grasped her mother’s meaning.

“I hated myself so much,” Nabulo said recently, recalling the words that preceded a period of sickness that left her hospitalized and feeding through a tube.

‘REMARKABLE’ GENE-EDITING TREATMENT FOR SICKLE CELL DISEASE IS APPROVED BY FDA

The scene underscores the lifelong challenges for some people with sickle cell disease in rural Uganda, where it remains poorly understood. Even Nabulo, despite her knowledge of how the disease weakens the body, spoke repeatedly of “the germ I was born with.”

Barbara Nabulo cleans clothes at her home in Busamaga-Mutukula village in Mbale, Uganda, on April 25, 2024. Nabulo, a sickle cell disease patient, has emerged as a dedicated advocate for others facing the same condition. (AP Photo/Hajarah Nalwadda)

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Sickle cell disease is a group of inherited disorders in which red blood cells — normally round — become hard, sticky and crescent shaped. The misshapen cells clog the flow of blood, which can lead to infections, excruciating pain, organ damage and other complications.

The disease, which can stunt physical growth, is more common in malaria-prone regions, notably Africa and India, because carrying the sickle cell trait helps protect against severe malaria. Global estimates of how many people have the disease vary, but some researchers put the number between 6 million and 8 million, with more than 5 million living in sub-Saharan Africa.

The only cure for the pain sickle cell disease can cause is a bone marrow transplant or gene therapies like the one commercially approved by the U.S. Food and Drug Administration in December. A 12-year-old boy last week became the first person to begin the therapy.

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Those options are beyond the reach of most patients in this East African nation where sickle cell disease is not a public health priority despite the burden it places on communities. There isn’t a national database of sickle cell patients. Funding for treatment often comes from donor organizations.

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In a hilly part of eastern Uganda that’s a sickle cell hot spot, the main referral hospital looks after hundreds of patients arriving from nearby villages to collect medication. Many receive doses of hydroxyurea, a drug that can reduce periods of severe pain and other complications, and researchers there are studying its effectiveness in Ugandan children.

Nabulo, now 37, is one of the hospital’s patients. But she approaches others like her as a caregiver, too.

After dropping out in primary school, she has emerged in recent years as a counselor to fellow patients, speaking to them about her survival. Encouraged by hospital authorities, she makes weekly visits to the ward that has many children watched over by exhausted-looking parents.

Nabulo tells them she was diagnosed with sickle cell disease at two weeks old, but now she is the mother of three children, including twins.

Such a message gives hope to those who feel discouraged or worry that sickle cell disease is a death sentence, said Dr. Julian Abeso, head of pediatrics at Mbale Regional Referral Hospital.

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Some men have been known to divorce their wives — or neglect them in search of new partners — when they learn that their children have sickle cell disease. Frequent community deaths from disease complications reinforce perceptions of it as a scourge.

BONE MARROW TRANSPLANTS CAN REVERSE ADULT SICKLE CELL DISEASE

Nabulo and health workers urge openness and the testing of children for sickle cell as early as possible.

Abeso and Nabulo grew close after Nabulo lost her first baby hours after childbirth in 2015. She cried in the doctor’s office as she spoke of her wish “to have a relative I can call mine, a descendant who can help me,” Abeso recalled.

“At that time, people here were so negative about patients with sickle cell disease having children because the complications would be so many,” the doctor said.

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Nabulo’s second attempt to have a child was difficult, with some time in intensive care. But her baby is now a 7-year-old boy who sometimes accompanies her to the hospital. The twin girls came last year.

Speaking outside the one-room home she shares with her husband and children, Nabulo said many people appreciate her work despite the countless indignities she faces, including unwanted stares from people in the streets who point to the woman with “a big head,” one manifestation in her of the disease. Her brothers often behave as if they are ashamed of her, she said.

Once, she heard of a girl in her neighborhood whose grandmother was making frequent trips to the clinic over an undiagnosed illness in the child. The grandmother was hesitant to have the girl tested for sickle cell when Nabulo first asked her. But tests later revealed the disease, and now the girl receives treatment.

“I go to Nabulo for help because I can’t manage the illness affecting my grandchild,” Kelemesiya Musuya said. “She can feel pain, and she starts crying, saying, ‘It is here and it is rising and it is paining here and here.’”

Musuya sometimes seeks reassurance. “She would be asking me, ‘Even you, when you are sick, does it hurt in the legs, in the chest, in the head?’ I tell her that, yes, it’s painful like that,” Nabulo said.

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Nabulo said she was glad that the girl, who is 11, still goes to school.

The lack of formal education is hurtful for Nabulo, who struggles to write her name, and a source of shame for her parents, who repeatedly apologize for letting her drop out while her siblings studied. One brother is now a medical worker who operates a clinic in a town not far away from Nabulo’s home

“I am very happy to see her,” said her mother, Agatha Nambuya.

She recalled Nabulo’s swelling head and limbs as a baby, and how “these children used to die so soon.”

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But now she knows of others with sickle cell disease who grew to become doctors or whatever they wanted to be. She expressed pride in Nabulo’s work as a counselor and said her grandchildren make her feel happy.

“At that time,” she said, recalling Nabulo as a child, “we didn’t know.”

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US economy expands at a surprisingly strong 4.3% annual rate in the third quarter

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US economy expands at a surprisingly strong 4.3% annual rate in the third quarter

WASHINGTON (AP) — The U.S. economy grew at a surprisingly strong 4.3% annual rate in the third quarter, the most rapid expansion in two years, as government and consumer spending, as well as exports, all increased.

U.S. gross domestic product from July through September — the economy’s total output of goods and services — rose from its 3.8% growth rate in the April-June quarter, the Commerce Department said Tuesday in a report delayed by the government shutdown. Analysts surveyed by the data firm FactSet forecast growth of 3% in the period.

However, inflation remains higher than the Federal Reserve would like. The Fed’s favored inflation gauge — called the personal consumption expenditures index, or PCE — climbed to a 2.8% annual pace last quarter, up from 2.1% in the second quarter.

A television on the floor at the New York Stock Exchange in New York, display a news conference with Fed chairman Jerome Powell, Wednesday, Dec. 10, 2025. (AP Photo/Seth Wenig)

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Excluding volatile food and energy prices, so-called core PCE inflation was 2.9%, up from 2.6% in the April-June quarter.

Economists say that persistent and potentially worsening inflation could make a January interest rate cut from the Fed less likely, even as central bank official remain concerned about a slowing labor market.

“If the economy keeps producing at this level, then there isn’t as much need to worry about a slowing economy,” said Chris Zaccarelli, chief investment officer for Northlight Asset Management, adding that inflation could return as the greatest concern about the economy.

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In a slow holiday trading week, U.S. markets on Wall Street turned lower following the GDP report, likely due to growing doubts that another Fed rate cut is coming next month.

Consumer spending, which accounts for about 70% of U.S. economic activity, rose to a 3.5% annual pace last quarter, up from 2.5% in the April-June period.

A person carries a shopping bag in Philadelphia, Wednesday, Dec. 10, 2025. (AP Photo/Matt Rourke, File)

A person carries a shopping bag in Philadelphia, Wednesday, Dec. 10, 2025. (AP Photo/Matt Rourke, File)

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Consumption and investment by the government grew by 2.2% in the quarter after contracting 0.1% in the second quarter. The third quarter figure was boosted by increased expenditures at the state and local levels and federal government defense spending.

Private business investment fell 0.3%, led by declines in investment in housing and in nonresidential buildings such as offices and warehouses. However, that decline was much less than the 13.8% slide in the second quarter.

Within the GDP data, a category that measures the economy’s underlying strength grew at a 3% annual rate from July through September, up slightly from 2.9% in the second quarter. This category includes consumer spending and private investment, but excludes volatile items like exports, inventories and government spending.

Exports grew at an 8.8% rate, while imports, which subtract from GDP, fell another 4.7%.

Tuesday’s report is the first of three estimates the government will make of GDP growth for the third quarter of the year.

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Outside of the first quarter, when the economy shrank for the first time in three years as companies rushed to import goods ahead of President Donald Trump’s tariff rollout, the U.S. economy has continued to expand at a healthy rate. That’s despite much higher borrowing rates the Fed imposed in 2022 and 2023 in its drive to curb the inflation that surged as the United States bounced back with unexpected strength from the brief but devastating COVID-19 recession of 2020.

Though inflation remains above the Fed’s 2% target, the central bank cut its benchmark lending rate three times in a row to close out 2025, mostly out of concern for a job market that has steadily lost momentum since spring.

Roofers work atop a house in Anna, Texas, Thursday, Dec. 18, 2025. (AP Photo/LM Otero)

Roofers work atop a house in Anna, Texas, Thursday, Dec. 18, 2025. (AP Photo/LM Otero)

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Last week, the government reported that the U.S. economy gained a healthy 64,000 jobs in November but lost 105,000 in October. Notably, the unemployment rate rose to 4.6% last month, the highest since 2021.

The country’s labor market has been stuck in a “low hire, low fire” state, economists say, as businesses stand pat due to uncertainty over Trump’s tariffs and the lingering effects of elevated interest rates. Since March, job creation has fallen to an average 35,000 a month, compared to 71,000 in the year ended in March. Fed Chair Jerome Powell has said that he suspects those numbers will be revised even lower.

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Israel calls out UN-backed Gaza famine report as biased, ignores aid flow and on-the-ground data

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Israel calls out UN-backed Gaza famine report as biased, ignores aid flow and on-the-ground data

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Israeli officials have slammed the latest report from an organization that earlier this year claimed there was famine in parts of Gaza, saying the new document is biased and that its conclusions were “predetermined.”

The Integrated Food Security Phase Classification (IPC), a United Nations-backed organization, previously claimed famine conditions were met in Gaza Governorate in August but now says that about 1.6 million Gazans are facing “high levels of acute food insecurity.

IDF Maj. Gen. Ghassan Alian, of the Coordinator of Government Activities in the Territories (COGAT), which deals with Gaza, called out what he said were “biased claims” by the IPC which he said, “disregard the volumes of food that entered during the ceasefire, indicating that the report’s conclusions were predetermined.”

ISRAEL PUSHES BACK AT ‘TAILOR-MADE’ UN-BACKED REPORT CLAIMING GAZA FAMINE

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Palestinians carry aid supplies which they received from the U.S.-backed Gaza Humanitarian Foundation, in the central Gaza Strip, May 29, 2025.  (Ramadan Abed/Reuters)

A statement from COGAT noted, “It is important to recall that this is not the first time IPC reports regarding the Gaza Strip have been published with extreme forecasts and warnings that do not materialize in practice. Time and again, IPC assessments have proven to be incorrect and disconnected from the data on the ground, contradicting verified facts, including aid volumes, food availability and market trends. The international community must act responsibly, avoid falling for false narratives and distorted information and refrain from legitimizing a biased and unprofessional report.”

In its latest report, the IPC’s Famine Review Committee addressed the changing circumstances, explaining that “following the publication of the [last] FRC report, there was a partial relaxation of the blockade and an increase in the availability of food and other essential supplies.” While the FRC says this “came too late to avoid famine in Gaza Governorate in July and early August, the persistence of Famine and its spread to other governorates during the projection period has been avoided.”

Gazans carry food airdropped by Jordan and the United Arab Emirates on July. 27 (TPS-IL)

In August, the IPC projected that two additional governorates would experience famine by Sept. 30. At the time, several experts disputed the presence of famine conditions, including Dr. David Adesnik, vice president of research at the Foundation for Defense of Democracies. Adesnik told Fox News Digital that mortality figures, while worrisome, did not reach levels expected during famine conditions. He also said that the prices on key food items had remained relatively stagnant or even declined during the period of alleged famine.

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Following the IPC’s latest report, Adesnik said that the IPC are still “dodging the question of proving that they were right” about prior famine declarations.

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In assessing the lack of mortality numbers that indicate famine, Adesnik said one of the IPC’s current arguments is that “data largely capture trauma-related deaths and overlook a substantial proportion of non-traumatic mortality.”  He called this “a big leap,” explaining “They’re basically saying that with all of its efforts to track down every name of someone killed during the war, the Gaza Ministry of Health somehow missed all the people who didn’t die because of bullets, shrapnel or falling buildings — that there’s just all these people who would have died of hunger, disease, other things.”

He said that the IPC’s figures show the highest number of malnutrition-related deaths per month being 27, with all malnutrition deaths peaking at 186. “Hundreds of people dying from malnutrition is still a terrible, terrible thing,” Adesnik said. “But we were asking a question: Is this famine? And that is not remotely close to the threshold for determining famine.”

Palestinians await donated food at a community kitchen in Jabalia, northern Gaza Strip, Monday, May 19, 2025. (Jehad Alshrafi/AP Photo)

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The IPC told Fox News Digital that to meet the famine threshold, “at least two in every 10,000 people” “or at least four in every 10,000 children under five are dying daily” on account of “outright starvation or the interaction of malnutrition and disease.”

US-BACKED AID GROUP ENDS GAZA MISSION AFTER DEFYING HAMAS THREATS, UN CRITICISM

In response to questions about its famine data, the IPC told Fox News Digital that “in the case of the Gaza analysis, there was clear evidence that thresholds for starvation and acute malnutrition had been reached, and analysts reasonably assessed from the broader evidence that the mortality threshold (third outcome) has likely been reached.”

Israel’s Ministry of Foreign Affairs spokesperson Oren Marmorstein said on X that “The IPC also disregards the fact that, on average, between 600 and 800 aid trucks enter the Gaza Strip every day, 70% of them carrying food – nearly five times more than what the IPC itself said was required for the Strip.”

Palestinians carry bags and boxes containing food and humanitarian aid packages delivered by the Gaza Humanitarian Foundation, a U.S.-backed organization, in Rafah, southern Gaza Strip, Monday, June 16, 2025. (Abdel Kareem Hana/AP Photo)

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Though it is not claiming famine is underway, the IPC still states that in a “worst-case scenario” of a return to conflict, “the entire Gaza Strip is at risk of famine through mid-April 2026.”

Adesnik said that the IPC is merely “guessing about the future.” He noted that accuracy from the IPC holds serious importance given the International Criminal Court and International Court of Justice’s allegations of war crimes and genocide against Israel. A declaration of famine would be a “big building block in what seems to prove part of the case.”

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Last week, the Secretary of State Marco Rubio, sanctioned two more members of the ICC for engaging “in efforts by the ICC to investigate, arrest, detain, or prosecute Israeli nationals, without Israel’s consent, including voting with the majority in favor of the ICC’s ruling against Israel’s appeal on December 15.

Secretary of State Marco Rubio said that the State Department “will continue to hold accountable those responsible for the ICC’s morally bankrupt and legally baseless actions against Americans and Israelis.”

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Trump says Greenland ‘essential’ for security: Could he take it by force?

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Trump says Greenland ‘essential’ for security: Could he take it by force?

President Donald Trump has said the United States needs Greenland for its “national security” after naming Louisiana Governor Jeff Landry as special envoy to the Danish Arctic island, prompting protests from Copenhagen.

“We need Greenland for national security, not for minerals,” Trump told reporters at his Mar-a-Lago residence in Florida on Monday, adding that Landry would “lead the charge”.

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Landry said he would make the Arctic territory “a part of the US”.

The comments drew sharp rebukes from Danish Prime Minister Mette Frederiksen and Greenland’s prime minister, Jens-Frederik Nielsen.

“You cannot annex another country … Not even with an argument about international security,” they said in a joint statement. “Greenland belongs to the Greenlanders and the US shall not take over Greenland,” they added.

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Since Trump returned to the White House in January, he has commented on several occasions about his desire for the mineral-rich island, a demand Denmark and many other European nations have steadfastly rejected.

So, what does Trump sending an envoy mean for Greenland, and could he succeed in acquiring it?

Why is Trump saying Greenland is ‘essential’ to US national security?

The US president insisted that the resource-rich island is “essential” for security reasons, rather than for its mineral resources.

“If you take a look at Greenland, you look up and down the coast, you have Russian and Chinese ships all over the place,” he said on Monday, while adding that the US has “many sites for minerals and oil”.

Trump’s interest in Greenland is not new.

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During his first term as US president from 2017 to 2021, he mooted the idea of buying the island from Denmark. Trump then postponed a 2019 visit to the Nordic country after Danish PM Frederiksen slammed the idea.

He has refused to rule out the use of military force to seize control, noting in March that the US would “go as far as we have to”.

Geographically part of North America, Greenland’s capital, Nuuk, lies about 2,900km (1,800 miles) from New York – closer than it is to Copenhagen, Denmark’s capital, which is situated roughly 3,500km (2,174 miles) to the east.

The semi-autonomous territory has a population of 57,000 people.

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Why has Trump sent an ‘envoy’ to Greenland – what does that signify?

On Sunday, the US president appointed Louisiana Governor Landry as special envoy to Greenland, prompting anger from Copenhagen, which summoned the US ambassador to explain the decision.

Following the announcement, Landry said it would be an honour to serve in a role meant to “make Greenland a part of the US”, further amplifying Denmark’s concerns about the White House’s intentions.

Taking to his social media platform Truth Social, Trump said Landry is aware “how essential Greenland is” for US national security.

Marc Jacobsen, a professor at the Royal Danish Defence College in Denmark, said while Trump is “clearly serious” about his interest in Greenland, it is unlikely he would try to take it by force.

“But we certainly see attempts to gain influence through other channels such as strategic investments and pushing narratives that portray Denmark as a bad partner,” Jacobsen told Al Jazeera.

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“The appointment of Jeff Landry as special envoy and Tom Dans as the leader of the US Arctic Research Commission should be seen as new elements in this strategy,” he added.

How have Greenlanders responded to this latest move?

Lokke Rasmussen, the foreign minister of Denmark, said Trump’s appointment of Landry confirmed continued US interest in Greenland.

“However, we insist that everyone – including the US – must show respect for the territorial integrity of the Kingdom of Denmark,” he told the AFP news agency.

On Monday, Greenland’s Prime Minister Nielsen said Greenland is friendly towards Washington and that “they know there is no obstacle to the United States increasing security in the Arctic on Greenlandic territory if they wish to do so.

“But going from that to pressuring to take over a country that is populated and has its own sovereignty is not acceptable,” Nielsen told the daily Sermitsiaq.

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People in Greenland broadly favour increased independence from Denmark – but not the transfer of sovereignty to the US.

In 2009, Denmark granted Greenland extensive self-governing powers, including the right to pursue independence from Denmark via a referendum.

In August, Denmark summoned the US charge d’affaires after at least three officials linked to former President Trump were spotted in Greenland’s capital, Nuuk, gauging local sentiment on strengthening ties with the US.

In March, US Vice President JD Vance and his wife, Usha Vance, were accompanied by White House National Security Advisor Mike Waltz and US Secretary of Energy Chris Wright on a tour of the US’s Pituffik Space Base in northwestern Greenland “to receive a briefing on Arctic security issues and meet with US service members”, according to a statement released by Vance’s office.

However, Greenland’s acting head of government, Mute Egede, wrote in an online post at the time that Greenland had not in fact extended any invitation for an official or private visit.

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In response to Landry’s announcement, European Union Commission President ⁠Ursula von der Leyen and European Council ‍President Antonio Costa said Arctic ‍security ‍was and will remain a “key priority” for the EU, “one in which we seek to work with allies and partners”.

“Territorial integrity and sovereignty are fundamental principles of international law. These principles ​are essential not ‌only for the European Union, but for nations around the world,” ‌they said ‌on ⁠X.

On Tuesday, French President Emmanuel Macron reiterated France’s backing for the sovereignty and territorial integrity of both Denmark and Greenland.

He said Greenland “belongs to its people” and Denmark “serves as its guarantor”.

Why is Greenland strategic for the US?

Trump has repeatedly emphasised that the Arctic’s strategic geography – particularly Greenland’s position between North America and Europe – is key to US defence and global security interests.

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Its location, offering the shortest route from North America to Europe, would give Washington leverage for its military and its ballistic missile early-warning system.

The US is also interested in placing radars in the waters that connect Greenland, Iceland and the United Kingdom. These waters are a gateway for Russian and Chinese ships, which the US wants to track.

The island also hosts the Pituffik Space Base, a major US military installation used for surveillance and missile warning operations.

What mineral resources does Greenland have?

Trump has denied that its mineral wealth is the real reason he is so interested in Greenland. However, it is rich in mineral resources critical for the production of modern technologies, including rare-earth elements for electronics and clean energy, as well as uranium, zinc and other base metals.

It also holds potential oil and gas deposits, though their extraction is restricted. Surveys indicate that Greenland contains a substantial share of the critical raw materials identified by the EU.

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INTERACTIVE-Greenlands mineral resources-MARCH9-2025-1741681526
(Al Jazeera)

Which other countries are scrambling for positions in the Arctic and why?

Several countries have become increasingly active in the Arctic in recent years.

Climate change and a rapidly melting ice sheet are the main reasons the Arctic has become a geopolitical hotspot.

The Arctic is heating at a rate four times faster than the global average, increasing its accessibility for maritime trade routes and resource exploration – including by non-Arctic countries as well as those with an Arctic presence.

China has deployed vessels capable of serving both military surveillance and research functions in the region. The purposes are to collect data and secure access to resources and shipping lanes, which are emerging as a result of melting ice.

Last year, Canada unveiled a 37-page security policy detailing plans to enhance its military and diplomatic presence in the Arctic, citing threats posed by increasing Russian and Chinese activity.

In recent years, Russia has expanded its naval presence, deploying missile systems and ramping up weapons testing in the Arctic.

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Russian President Vladimir Putin has also noted Trump’s interest in the region.

During an address at the International Arctic Forum in the Russian city of Murmansk, the largest city within the Arctic circle, earlier this year, Putin said he believed Trump was serious about taking Greenland and that the US would continue its efforts to acquire it.

“It can look surprising only at first glance, and it would be wrong to believe that this is some sort of extravagant talk by the current US administration,” said Putin, adding that he expects the US to continue to “systematically advance its geostrategic, military-political and economic interests in the Arctic”.

Putin also expressed concerns about Russia’s neighbours, Finland and Sweden – both of which have borders inside the Arctic circle – joining NATO, the transatlantic military alliance between North America and Europe. Finland joined NATO in 2023, and Sweden joined in 2024.

“Russia has never threatened anyone in the Arctic, but we will closely follow the developments and mount an appropriate response by increasing our military capability and modernising military infrastructure,” Putin said.

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Could the US take Greenland by force?

Jacobsen said if the US were to invade Greenland, it would mean the end of the North Atlantic Treaty Organization (NATO).

Denmark and the US are founding members of NATO, a European and North American military alliance founded in 1949.

“On a personal level for Trump, it would also mean the end of any ambitions for getting a peace prize, which he has strived for so long,” Jacobsen told Al Jazeera.

“All his efforts to end the wars in Ukraine, Israel-Palestine and elsewhere would have no effect to this end.”

Jacobsen added that there are still “reasonable people in the right positions” who would pull the “handbrake on such an unreasonable idea like invading Greenland”.

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“I truly don’t believe it will happen,” he added.

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