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Matthew Perry's death leads to sweeping indictment of 5, including doctors and reputed dealers

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Matthew Perry's death leads to sweeping indictment of 5, including doctors and reputed dealers

LOS ANGELES (AP) — Nearly 10 months after the death of Matthew Perry, the long-simmering investigation into the ketamine that killed him came dramatically into public view with the announcement that five people had been charged with having roles in the overdose of the beloved “Friends” star.

Here are key things to know about the case, including the two key figures who could be headed for trial and the possibility of the steepest of prison sentences.

A sweeping set of indictments

One or more arrests had been expected since investigators from three different agencies revealed in May they had been conducting a joint probe into how the 54-year-old Perry got such large amounts of ketamine.

The actor had been among the growing number of patients using legal but off-label medical means to treat depression, or in other cases chronic pain, with the powerful surgical anesthetic.

Recent reports suggested indictments might be imminent, but few outside observers, if any, knew how wide-ranging the prosecution would be, reaching much further than previous cases stemming from celebrity overdoses.

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When Michael Jackson died in 2009 from a lethal dose of the anesthetic propofol, his doctor was charged with providing it. After rapper Mac Miller died in 2017, two men who prosecutors described as a dealer and a middleman were convicted of providing fentanyl-laced oxycodone that helped kill him.

But Perry’s case pulled in both, with indictments against doctors and illegal distributors who prosecutors say preyed on his long and public struggles with addiction. The investigation even went after the live-in personal assistant who prosecutors say helped him get ketamine and injected it directly into him before Perry was found dead in his hot tub on Oct. 28, 2023.

“They knew what they were doing was risking great danger to Mr. Perry. But they did it anyway,” U.S. Attorney Martin Estrada said in announcing the charges.

The prosecution was well under way even before the announcement. Two people including the assistant, Kenneth Iwamasa, and a Perry acquaintance, Eric Fleming, have pleaded guilty to conspiracy to distribute the drug. A San Diego physician, Dr. Mark Chavez, has agreed to enter a guilty plea.

That leaves prosecutors free to pursue their two biggest targets.

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The doctor and the ‘Ketamine Queen’

An indictment unsealed Thursday alleges Perry turned to Los Angeles doctor Salvador Plasencia when his regular doctors refused to give him more ketamine. Prosecutors allege Plasencia cashed in on Perry’s desperation and addiction, getting him to pay $55,000 in cash for large amounts of the drug in the two months before his death.

“I wonder how much this moron will pay,” Plasencia texted a co-defendant, according to his indictment.

He pleaded not guilty to seven counts of distribution of ketamine in an appearance in federal court on Thursday afternoon.

Plasencia’s attorney, Stefan Sacks, said outside court that he “was operating with what he what he thought were the best of medical intentions,” and his actions “certainly didn’t rise to the level of criminal misconduct.”

Prosecutors allege Jasveen Sangha, whom they describe as a drug dealer known to customers as the “Ketamine Queen,” provided the doses of the drug that actually killed Perry, injected into the actor by Iwamasa with syringes supplied by Plasencia.

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Sangha also pleaded not guilty. Her attorney Alexandra Kazarian derided the “queen” moniker as made-for-media consumption during the hearing. The lawyer declined comment on the case outside court.

Prosecutors say the other doctor in the case, Chavez, helped Plasencia obtain the ketamine he gave to Perry, while Perry’s acquaintance, Fleming, helped get ketamine from Sangha to Perry.

Chavez could get up to 10 years in prison, Iwamasa up to 15 years and Fleming up to 25 years.

Multiple messages seeking comment from attorneys for the three men were not returned.

Looking ahead to trial

Sangha could get life in prison if convicted as charged, while Plasencia could get up to 120 years. Each has a trial date in October, but it is highly unlikely any would be facing a jury by then, and the two may be tried together. They also could face testimony from the co-defendants who reached plea agreements.

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Magistrate Judge Alka Sagar ruled Sangha should be held without bond while awaiting trial, citing prosecutors’ contentions that she had destroyed evidence and funded a lavish lifestyle with drug sales even after Perry’s death.

The judge agreed to release Plasencia after he posted a $100,000 bond.

His attorney argued the Perry case was “isolated” and the doctor should be allowed to treat patients who depended on him at his one-man practice while awaiting trial.

“I’m not buying that argument,” Sagar said, but agreed Plasencia could see patients so long as they signed a document in which he acknowledged the charges.

“People have probably already heard about it from the amount of press,” Sacks told the judge, noting if they hadn’t, they would soon.

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Records show Plasencia’s medical license has been in good standing with no records of complaints, though it is set to expire in October and he could face action. He already has surrendered his federal license to prescribe more dangerous drugs.

Pushing back against ketamine

Prosecutors and police presented the Perry case as part of a major pushback against a rise in the illegal use of ketamine that has shadowed the broadening of its legal use.

Los Angeles police said in May they were working with the U.S. Drug Enforcment Administration and the U.S. Postal Inspection Service with a probe into how Perry got the drug. His autopsy, released in December, found the amount of ketamine in his blood was in the range used for general anesthesia during surgery.

“As Matthew Perry’s ketamine addiction grew, he wanted more and he wanted it faster and cheaper. That is how he ended up buying from street dealers and stole the ketamine that ultimately led to his death,” U.S. Drug Enforcement Administrator Anne Milgram said Thursday. “In doing so, he followed the arc that we have tragically seen with many others. The substance use disorder begins in a doctor’s office and ends in the street.”

Perry had years of struggles with addiction dating back to his time on NBC’s megahit sitcom, “Friends,” for 10 seasons from 1994 to 2004. Playing Chandler Bing, he became one of the biggest television stars of his generation alongside Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matt LeBlanc and David Schwimmer.

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Live updates: Tracking Venezuela oil tankers as US seizes Russian-flagged vessel

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Live updates: Tracking Venezuela oil tankers as US seizes Russian-flagged vessel

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Kylie is the Global Live Pages Editor, leading a team providing real-time multimedia coverage of the biggest breaking stories worldwide. She previously worked on the UK Breaking News team, and spent eight years in Westminster as a UK political correspondent – a period which included the Scottish independence referendum, Brexit and several general elections. She originally joined Reuters as a graduate trainee and has also covered investment banking.

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Vanessa Balintec is a Live Page Journalist based in Toronto, Ontario. She helps create and curate multimedia posts for Reuters’ Live Pages — a scrolling feed of multimedia posts for some of the biggest stories of the day. She previously worked at various bureaus for CBC News. Contact: vanessa.balintec@thomsonreuters.com

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Iranian protesters rename Tehran street after Trump, plead ‘don’t let them kill us’ amid crackdown

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Iranian protesters rename Tehran street after Trump, plead ‘don’t let them kill us’ amid crackdown

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Iranian protesters intensified nationwide demonstrations over the past 24 hours, directly appealing to President Donald Trump while chanting anti-regime slogans. Footage published Wednesday showed a protester in Tehran symbolically renaming a street after Trump, while other videos captured handwritten appeals reading, “Don’t let them kill us,” Iran International reported.

Holly Dagres, a senior fellow at the Washington Institute, posted the video on X stating, “Since Trump’s comments about the Iran protests, I’ve seen numbers videos of Iranian protesters either thanking him or, in this case, renaming streets after the US president.”

The appeals came as demonstrators faced a widening security crackdown, including the deployment of armed units and tear gas near major civilian sites in Tehran.

TRUMP SIGNS ‘MAKE IRAN GREAT AGAIN’ HAT ALONGSIDE LINDSEY GRAHAM

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Exiled Iranian opposition leader Reza Pahlavi said the current unrest represents a historic opportunity to end Iran’s Islamic Republic.

“In all these years, I’ve never seen an opportunity as we see today in Iran,” Pahlavi said in an interview aired Tuesday on “Hannity.”

“Iranian people are more than ever committed to bringing an end to this regime, as the world has witnessed in the last few days, the level of demonstrations is unprecedented in Iran,” he said.

Pahlavi said protests have spread to more than 100 cities and emphasized the role of Iran’s traditional merchant class, describing developments inside the country’s bazaars as a turning point. “We are beginning to see more and more defections,” Pahlavi said, adding that “Either way, the regime is crumbling and is very close to collapsing.”

IRAN ON THE BRINK AS PROTESTERS MOVE TO TAKE TWO CITIES, APPEAL TO TRUMP

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Sen. Lindsey Graham, R-S.C., posted a photo of himself posing with President Donald Trump, who is holding a signed “Make Iran Great Again” hat. (Lindsey Graham / X)

Over the past 24 hours, Iran International reported continued protests and strikes across the country, including in Tehran, Tabriz, Qazvin, Kermanshah, Kerman, Shiraz, Falavarjan and Bandar Abbas. Tehran’s Grand Bazaar remained a focal point of unrest, with large crowds chanting against Iran’s leadership as authorities responded with tear gas and armed deployments.

Security operations expanded into sensitive civilian locations. Videos published by Iran International showed tear gas used near or inside Tehran’s Sina Hospital and the Plasco Shopping Center.

Protesters hold signs during a demonstration in Iran amid ongoing unrest, according to images released by the Iranian opposition group National Council of Resistance of Iran. (NCRI )

Casualty and arrest figures continued to rise. The Human Rights Activists News Agency, cited by Iran International on Wednesday, reported at least 36 people killed since protests began, including 34 protesters and two members of Iran’s security forces, with more than 2,000 arrests nationwide. Iranian authorities have not released updated official figures.

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New footage from the past day showed demonstrators lighting fires in the streets of Shiraz and chanting “Death to Khamenei,” referring to Supreme Leader Ali Khamenei. In Qazvin, protesters were heard chanting, “Law enforcement, return to the side of the nation.”

Iranian protesters try to take control of two cities in western Iran as nationwide unrest continues, with demonstrators chanting ‘Death to Khamenei’ in the streets. (Getty)

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Workers also joined the unrest, with strikes reported at the South Pars gas refinery and widespread shop closures at major markets in Tehran and Tabriz.

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How Ukraine is shaping Europe’s response to Trump’s Greenland threats

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How Ukraine is shaping Europe’s response to Trump’s Greenland threats

For the past year, staying in Donald Trump’s good graces has become a top priority for European leaders, who have gone the extra mile to appease the mercurial US president, rein in his most radical impulses and keep him firmly engaged in what is their be-all and end-all: Russia’s war on Ukraine.

Though Europe is by far the largest donor to Kyiv, nobody on the continent is under the illusion that the invasion can be resisted without US-made weapons and come to an eventual end without Washington at the negotiating table.

In practice, the strategic calculus has translated into painful sacrifices, most notably the punitive tariffs that Trump forced Europeans to endure.

“It’s not only about the trade. It’s about security. It is about Ukraine. It is about current geopolitical volatility,” Maroš Šefčovič, the European Commissioner for Trade, said in June as he defended the trade deal that imposed a sweeping 15% tariff on EU goods.

The same thinking is now being replicated in the saga over Greenland’s future.

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As the White House ramps up its threats to seize the vast semi-autonomous island, including, if necessary, by military force, Europeans are walking an impossibly thin line between their moral imperative to defend Denmark’s territorial integrity and their deep-rooted fear of risking Trump’s wrath.

The precarity of the situation was laid bare at this week’s meeting of the “Coalition of the Willing” in Paris, which French President Emmanuel Macron convened to advance the work on security guarantees for Ukraine.

The high-profile gathering was notable because of the first-ever in-person participation of Steve Witkoff and Jared Kushner, the chief negotiators appointed by Trump.

At the end of the meeting, Macron hailed the “operational convergence” achieved between Europe and the US regarding peace in Ukraine. By his side, British Prime Minister Keir Starmer was equally sanguine, speaking of “excellent progress”.

But it did not take long for the elephant in the room to make an appearance.

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Hard pivot

The first journalist who took the floor asked Macron whether Europe could “still trust” America in light of the threats against Greenland. In response, the French president quickly highlighted the US’s participation in the security guarantees.

“I have no reason to doubt the sincerity of that commitment,” Macron said. “As a signatory of the UN charter and a member of NATO, the United States is here as an ally of Europe, and it is, as such, that it has worked alongside us in recent weeks.”

Starmer was also put on the spot when a reporter asked him about the value of drafting security guarantees for a country at war “on the very day” that Washington was openly talking about seizing land from a political ally.

Like Macron, Starmer chose to look at the bright side of things.

“The relationship between the UK and the US is one of our closest relationships, particularly on issues of defence, security and intelligence,” the British premier said. “And we work with the US 24/7 on those issues.”

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Starmer briefly referred to a statement published earlier on Tuesday by the leaders of France, Germany, Italy, Poland, Spain, the UK and Denmark in defence of Greenland.

The statement obliquely reminded the US to uphold “the principles of sovereignty, territorial integrity and the inviolability of borders” enshrined in the UN Charter – precisely the same tenets that Moscow is violating at large in Ukraine.

The text did not contain any explicit condemnation of the goal to forcefully annex Greenland and did not spell out any potential European retaliation.

“Greenland belongs to its people. It is for Denmark and Greenland, and them only, to decide on matters concerning Denmark and Greenland,” its closing paragraph read.

Conspicuous silence

The lack of censure was reminiscent of the European response to the US operation that just a few days earlier removed Nicolás Maduro from power in Venezuela.

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Besides Spain, which broke ranks to denounce the intervention as a blatant breach of international law, Europeans were conspicuously silent on legal matters. Rather than condemn, they focused on Venezuela’s democratic transition.

Privately, officials and diplomats concede that picking up a fight with Trump over Maduro’s removal, a hostile dictator, would have been counterproductive and irresponsible in the midst of the work to advance security guarantees for Ukraine.

The walking-on-eggs approach, however, is doomed to fail when it comes to Greenland, a territory that belongs to a member of both the EU and NATO.

Danish Prime Minister Mette Frederiksen has warned that the entire security architecture forged at the end of World War II, which allies have repeatedly invoked to stand up to the Kremlin’s neo-imperialism, would collapse overnight in the event of an annexation. The worry is that trying to stay in Trump’s good graces at all costs might come at an unthinkable price.

“Europeans are clearly in a ‘double-bind’: Since they are in desperate need of US support in Ukraine, their responses to US actions – whether on Venezuela or Trump threatening Denmark to annex Greenland – are weak or even muted,” said Markus Ziener, a senior fellow at the German Marshall Fund.

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“Europeans are afraid that criticising Trump could provide a pretext for the US president to conclude a peace deal at Ukraine’s and Europe’s expense. Is this creating a credibility gap on the part of the EU? Of course. But confronted with a purely transactional US president, there seems to be no other way.”

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