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Matthew Perry's death leads to sweeping indictment of 5, including doctors and reputed dealers
LOS ANGELES (AP) — Nearly 10 months after the death of Matthew Perry, the long-simmering investigation into the ketamine that killed him came dramatically into public view with the announcement that five people had been charged with having roles in the overdose of the beloved “Friends” star.
Here are key things to know about the case, including the two key figures who could be headed for trial and the possibility of the steepest of prison sentences.
A sweeping set of indictments
One or more arrests had been expected since investigators from three different agencies revealed in May they had been conducting a joint probe into how the 54-year-old Perry got such large amounts of ketamine.
The actor had been among the growing number of patients using legal but off-label medical means to treat depression, or in other cases chronic pain, with the powerful surgical anesthetic.
Recent reports suggested indictments might be imminent, but few outside observers, if any, knew how wide-ranging the prosecution would be, reaching much further than previous cases stemming from celebrity overdoses.
When Michael Jackson died in 2009 from a lethal dose of the anesthetic propofol, his doctor was charged with providing it. After rapper Mac Miller died in 2017, two men who prosecutors described as a dealer and a middleman were convicted of providing fentanyl-laced oxycodone that helped kill him.
But Perry’s case pulled in both, with indictments against doctors and illegal distributors who prosecutors say preyed on his long and public struggles with addiction. The investigation even went after the live-in personal assistant who prosecutors say helped him get ketamine and injected it directly into him before Perry was found dead in his hot tub on Oct. 28, 2023.
“They knew what they were doing was risking great danger to Mr. Perry. But they did it anyway,” U.S. Attorney Martin Estrada said in announcing the charges.
The prosecution was well under way even before the announcement. Two people including the assistant, Kenneth Iwamasa, and a Perry acquaintance, Eric Fleming, have pleaded guilty to conspiracy to distribute the drug. A San Diego physician, Dr. Mark Chavez, has agreed to enter a guilty plea.
That leaves prosecutors free to pursue their two biggest targets.
The doctor and the ‘Ketamine Queen’
An indictment unsealed Thursday alleges Perry turned to Los Angeles doctor Salvador Plasencia when his regular doctors refused to give him more ketamine. Prosecutors allege Plasencia cashed in on Perry’s desperation and addiction, getting him to pay $55,000 in cash for large amounts of the drug in the two months before his death.
“I wonder how much this moron will pay,” Plasencia texted a co-defendant, according to his indictment.
He pleaded not guilty to seven counts of distribution of ketamine in an appearance in federal court on Thursday afternoon.
Plasencia’s attorney, Stefan Sacks, said outside court that he “was operating with what he what he thought were the best of medical intentions,” and his actions “certainly didn’t rise to the level of criminal misconduct.”
Prosecutors allege Jasveen Sangha, whom they describe as a drug dealer known to customers as the “Ketamine Queen,” provided the doses of the drug that actually killed Perry, injected into the actor by Iwamasa with syringes supplied by Plasencia.
Sangha also pleaded not guilty. Her attorney Alexandra Kazarian derided the “queen” moniker as made-for-media consumption during the hearing. The lawyer declined comment on the case outside court.
Prosecutors say the other doctor in the case, Chavez, helped Plasencia obtain the ketamine he gave to Perry, while Perry’s acquaintance, Fleming, helped get ketamine from Sangha to Perry.
Chavez could get up to 10 years in prison, Iwamasa up to 15 years and Fleming up to 25 years.
Multiple messages seeking comment from attorneys for the three men were not returned.
Looking ahead to trial
Sangha could get life in prison if convicted as charged, while Plasencia could get up to 120 years. Each has a trial date in October, but it is highly unlikely any would be facing a jury by then, and the two may be tried together. They also could face testimony from the co-defendants who reached plea agreements.
Magistrate Judge Alka Sagar ruled Sangha should be held without bond while awaiting trial, citing prosecutors’ contentions that she had destroyed evidence and funded a lavish lifestyle with drug sales even after Perry’s death.
The judge agreed to release Plasencia after he posted a $100,000 bond.
His attorney argued the Perry case was “isolated” and the doctor should be allowed to treat patients who depended on him at his one-man practice while awaiting trial.
“I’m not buying that argument,” Sagar said, but agreed Plasencia could see patients so long as they signed a document in which he acknowledged the charges.
“People have probably already heard about it from the amount of press,” Sacks told the judge, noting if they hadn’t, they would soon.
Records show Plasencia’s medical license has been in good standing with no records of complaints, though it is set to expire in October and he could face action. He already has surrendered his federal license to prescribe more dangerous drugs.
Pushing back against ketamine
Prosecutors and police presented the Perry case as part of a major pushback against a rise in the illegal use of ketamine that has shadowed the broadening of its legal use.
Los Angeles police said in May they were working with the U.S. Drug Enforcment Administration and the U.S. Postal Inspection Service with a probe into how Perry got the drug. His autopsy, released in December, found the amount of ketamine in his blood was in the range used for general anesthesia during surgery.
“As Matthew Perry’s ketamine addiction grew, he wanted more and he wanted it faster and cheaper. That is how he ended up buying from street dealers and stole the ketamine that ultimately led to his death,” U.S. Drug Enforcement Administrator Anne Milgram said Thursday. “In doing so, he followed the arc that we have tragically seen with many others. The substance use disorder begins in a doctor’s office and ends in the street.”
Perry had years of struggles with addiction dating back to his time on NBC’s megahit sitcom, “Friends,” for 10 seasons from 1994 to 2004. Playing Chandler Bing, he became one of the biggest television stars of his generation alongside Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matt LeBlanc and David Schwimmer.
World
Electric bikes can be fast and dangerous. Here’s how to stay safe
SIOUX FALLS, S.D. (AP) — The 14-year-old was riding an electric bicycle at an estimated 25 mph when he slammed into Janet Stotko during her evening walk, leaving her unconscious and bleeding on a sidewalk in her Minnesota neighborhood.
The 2024 crash nearly killed Stotko, who was raced to a hospital with severe brain injuries, a facial fracture and broken eardrum. But after being on a ventilator for two days, spending three weeks in the hospital and enduring brain surgery, she survived, surprising even her doctors.
At a checkup, she said, her doctors told her, “Wow, we can’t believe you’re here.”
Now, she’s pushing for stricter laws regulating e-bikes in hopes that others won’t be hurt.
E-bikes offer a convenient, eco-friendly and cost-effective alternative to cars, but their increasing use is drawing safety concerns. A study by the University of California, San Francisco found that rider injuries from e-bikes nearly doubled each year from 2017 to 2022, and a University of California, San Diego study showed injuries in San Diego among e-bike riders under 18 soared 300% from 2019 to 2023.
Under federal law, most e-bikes are considered nonmotorized vehicles just like traditional bicycles, so riders don’t need a driver’s license or insurance and they don’t have to wear a helmet. But many states have more stringent rules, and regulations vary widely.
Health experts have called for new laws and better enforcement of existing regulations, and officials in many places are taking action.
Here’s what e-bikers should know to keep themselves and people around them safe.
This article is part of AP’s Be Well coverage, focusing on wellness, fitness, diet and mental health. Read more Be Well.
Not all e-bikes are the same
Many states have adopted a three-tier classification of e-bikes: Class 1 have motors that kick in while riders pedal with maximum speeds of 20 mph; Class 2 have throttles that reach the 20 mph maximum without pedaling; and Class 3 provide pedal-assist up to 28 mph.
There are faster versions available, sometimes called e-motos, that can reach 40 mph even without pedaling. Many states treat these bikes like motorcycles, so they’re not allowed on sidewalks or paths, but in some states there are no specific rules for the ultra-fast bikes.
As John Maa, a general surgeon at MarinHealth Medical Center in Northern California, notes, it’s basic math that increased speeds lead to increased injuries.
“It’s Newton’s principles, right? Force equals mass times acceleration, and also kinetic energy is mass times velocity squared,” Maa said.
Learn where you can and can’t ride
Speed limits, helmet requirements and other rules for e-bikes are changing rapidly, and what’s legal in one city or state might be illegal in the next.
New York City imposed a speed limit of 15 mph on all electric bikes in October, and Florida lawmakers recently sent the governor a bill limiting e-bike speeds to 10 mph within 50 feet of pedestrians. In Connecticut, an October law requires all e-bike riders to wear a helmet, and bikes without pedals equipped with batteries over 750 watts will require a driver’s license.
“We were not only hearing from manufacturers and riders, but we were hearing from concerned citizens trying to share the road with these new electric bikes and e-scooters, and also law enforcement who really needed some clear policies set into place,” said Christine Cohen, the Connecticut state senator behind the legislation.
Know your bike
The market is full of vehicles that blur the line between a traditional e-bike and something closer to a motorcycle, and manufacturers don’t always make the distinction easy to spot.
To understand a bike’s capabilities and where it can be legally ridden, check its top speed, motor wattage, and whether it requires pedaling or operates on throttle alone. Anything outside the three-class classification could be subject to motor vehicle regulations, making it illegal to ride on some shared-use paths where slower e-bikes are allowed.
“The first thing we always tell people is familiarize yourself, read the manual, look at some videos, look at your specific model,” said Charles DiMaggio, an injury public health researcher and professor at New York University’s medical school.
Going to a local bike shop instead of buying online can help, enabling riders to ask questions, take a test ride and learn what’s legal and what isn’t.
Follow traditional bike safety measures
Hospitals and medical groups like the American College of Surgeons and American Association of Neurological Surgeons have called for stricter policies and offered safety tips.
Above all, they stress wearing a helmet. Other tips include riding defensively around cars, using front and rear lights, wearing reflective vests in the dark, and avoiding biking under the influence of drugs or alcohol. Experts also recommend against altering an e-bike to make it faster.
Maa added that e-bike riders should consider wearing a motorcycle helmet that covers the neck to protect against spinal injuries. He also advises parents to make sure their children can comfortably ride a pedal bike before they graduate to e-bikes.
“Make sure they’re comfortable, they understand the rules of the road, they’re able to navigate turns, understand the flow of traffic, the use of bicycle lanes,” Maa said.
Minnesota victim wants accountability
After she was injured, Stotko told the city council in her community of Hastings, Minnesota, about her crash to push for a stricter ordinance. The city agreed, reducing maximum e-bike speeds to 15 mph on city trails, prohibiting e-bikes on sidewalks and imposing penalties.
City police issued a citation to the 14-year-old rider for operating an e-bike underage, but no one was charged for the injury to Stotko.
“It’s really about taking accountability and ownership of owning an e-bike and operating one,” she said.
World
Zelenskyy offers cutting-edge drone defense to Gulf allies as Ukraine seeks missile support
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Ukrainian President Volodymyr Zelenskyy is turning battlefield innovation into bargaining power, offering Ukraine’s anti-drone systems to Middle Eastern allies, while seeking more air-defense support as the war with Russia drags into its fourth year.
Zelenskyy met Friday in Abu Dhabi with United Arab Emirates (UAE) President Mohammed bin Zayed Al Nahyan, and the two discussed an agreement by which Ukraine would provide its cutting-edge counter-drone technology in exchange for ballistic missile support and financial aid.
In a wide-ranging interview with Fox News after the meeting, Zelenskyy detailed how Ukraine’s battlefield innovations, namely its anti-Russian drone systems, are influencing defense partnerships worldwide.
ZELENSKYY ANNOUNCES NEXT ROUND OF TALKS WITH US, RUSSIA AS UKRAINE AIMS FOR ‘REAL AND DIGNIFIED END TO THE WAR
In a wide-ranging interview with Fox News, Ukrainian President Volodymyr Zelenskyy detailed how Ukraine’s battlefield innovations are influencing defense partnerships worldwide. (Fox News)
“We have, for example, drone interceptors. We have [a] system of electronic warfare and a lot of things. All these jointly work in one system. This is what we have [that] nobody has,” Zelenskyy told Fox News correspondent Matt Finn in Abu Dhabi.
Ukraine is now sharing elements of that system with at least four Persian Gulf nations — the UAE, Qatar, Jordan and Saudi Arabia — as they confront growing threats from Iran’s drone capabilities.
But Zelenskyy emphasized the partnership must be reciprocal. Ukraine continues to face a “big deficit” of critical air defense weapons, particularly PAC-3 Patriot missiles used to intercept ballistic threats.
“We are ready to help Middle East countries with our expertise and with our knowledge, and we hope … that they can help with anti-ballistic missiles,” Zelenskyy said.
Ukraine has already signed 10-year defense agreements with Saudi Arabia and Qatar, with a similar deal with the UAE expected soon, according to the AP.
TRUMP MEETS WITH ZELENSKYY; TALKS COULD UNLOCK FIRST ZELENSKYY-PUTIN CALL IN FIVE YEARS: SOURCE
A plume of smoke rises from the site of a strike in Tehran early on March 28, 2026. (Atta Kenare/AFP via Getty Images)
Zelenskyy also warned that increasing U.S. military focus on the Middle East amid escalating tensions with Iran and the ongoing “Operation Epic Fury” could slow the flow of weapons to Ukraine.
He claimed Russia is already strengthening Iran’s military by sharing drone technology, including Shahed “kamikaze” drones, as well as battlefield tactics developed during the war.
“Russia will share all they know about this war. … They’re already sharing with Iranians,” Zelenskyy said.
While he stopped short of confirming missile transfers, Zelenskyy suggested Moscow has a strategic interest in prolonging instability in the Middle East to divert U.S. attention away from Ukraine.
“This is what they do,” Zelenskyy said.
On the battlefield, Zelenskyy reiterated that Ukraine will not cede territory in the contested Donbas region, arguing it would weaken defenses, damage troop morale and displace tens of thousands of civilians.
“I think their morale will decrease,” Zelenskyy said.
He also urged the Trump administration not to lose sight of Ukraine while addressing Middle East tensions.
AS UKRAINE WAR DRAGS ON, TRUMP HITS PUTIN BY SQUEEZING RUSSIA’S PROXIES
Destroyed homes after a Russian drone attack March 28 in Odesa, Ukraine. (Viacheslav Onyshchenko/Global Images Ukraine via Getty Images)
More than 270 Russian drones struck Ukraine overnight Friday, leaving at least five people dead, Ukrainian officials said Saturday, according to AP.
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“I hope that President Trump … will find a way to end this war with pressure on the Iranian regime, and I hope that also they will not forget about … the war of Russia against Ukraine,” Zelenskyy said.
The Associated Press contributed to this report.
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