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Alzheimer’s blood test shows 90% accuracy, outperforming other exams

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Alzheimer’s blood test shows 90% accuracy, outperforming other exams


A new study shows that a simple blood test can outperform traditional exams when it comes to determining whether Alzheimer’s is responsible for memory problems, accurately diagnosing the disease about 90 percent of the time.

Compare that with dementia specialists who successfully identified Alzheimer’s 73 percent of the time, while primary care doctors did so with a 61 percent rate, according to the study of 1,213 patients in Sweden that was published Sunday on JAMA, the journal published by the American Medical Association, and presented at the Alzheimer’s Association International Conference on the same day in Philadelphia.

The encouraging findings come amid larger efforts to develop a cheap, simple blood test that can quickly diagnose patients with Alzheimer’s without forcing people to undergo more expensive and invasive exams, such as spinal taps. Although blood tests are already used in clinics, they are often not covered by insurance, costing hundreds of dollars or more.

“Overall, this is a nice addition to a rapidly growing literature, although not necessarily a game changer per se,” said Cliff Abraham, a professor of neuroscience and psychology at the University of Otago in New Zealand who was not involved in the study.

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The study’s authors compiled data from patients with cognitive symptoms whose mean age was 74. About 23 percent of them had subjective cognitive decline, 44 percent mild cognitive impairment and 33 percent dementia.

The authors measured the level of p-tau217, a type of protein that builds up and impairs the brain in Alzheimer’s patients, and amyloid beta, another protein that is considered a biomarker of Alzheimer’s.

“It is clear, but not surprising, that the blood test offers better diagnostic accuracy than clinical evaluation, which has access to only indirect information about brain health, for example cognitive tests,” Abraham said.

Alternatives for diagnosing Alzheimer’s include PET scans, which can cost $5,000 or more, and are not covered by Medicare except in trials, while spinal taps are invasive.

The study adds to evidence that diagnosing Alzheimer’s could soon be done more quickly and easily. Faster and more accurate diagnoses allow patients and their families to better prepare for medical bills, enroll in clinical trials or anticipate care needs, according to the Centers for Disease Control and Prevention.

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Alzheimer’s is the most common form of dementia, afflicting more than 6 million Americans. Although younger people can get Alzheimer’s, most patients are elderly, with the number of patients doubling every five years beyond age 65, according to the CDC. Up to 14 million Americans may have Alzheimer’s by 2060.

The disease begins with mild memory loss but can progress to patients losing the ability to carry on a conversation. It is one of the top 10 causes of death in the United States, with death rates climbing. There is no cure, although there are drugs that can slow the disease.



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Washington Spirit goalkeeper Aubrey Kingsbury announces she’s pregnant

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Washington Spirit goalkeeper Aubrey Kingsbury announces she’s pregnant


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Washington Spirit goalkeeper Aubrey Kingsbury has announced that she and her husband Matt are expecting a baby in July.

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The couple made the announcement in a video on the Spirit’s social media channels, holding a baby goalkeeper jersey on the pitch at Audi Field.

Kingsbury becomes the most recent Spirit star to go on maternity leave, following defender Casey Krueger, midfielder Andi Sullivan and forward Ashley Hatch.

Sullivan gave birth to daughter Millie in July, while Hatch welcomed her son Leo in January.

Krueger announced she was pregnant with her second child in October.

Kingsbury has served as the Spirit’s starting goalkeeper since 2018, and has been named the NWSL Goalkeeper of the Year twice (2019 and 2021).

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The 34-year-old has two caps with the U.S. women’s national team, and was named to the 2023 World Cup roster.

The club captain will leave a major void for the Spirit, who have finished as NWSL runner-up in back-to-back seasons.

Sandy MacIver and Kaylie Collins are expected to compete for the starting role while Kingsbury is on maternity leave.

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The Spirit kick off their 2026 campaign on March 13 against the Portland Thorns.





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Washington state board awards Yakima $985,600 loan for Sixth Avenue project design

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Washington state board awards Yakima 5,600 loan for Sixth Avenue project design


Yakima could soon take a major step toward redesigning Sixth Avenue after the Washington State Public Works Board awarded the city a $985,600 loan.

The loan was approved for the design engineering phase of the Sixth Avenue project. The funding can also be used along Sixth Avenue for utility replacement and updated ADA use.

The Yakima City Council must decide whether to accept the award. If the council accepts it, the city’s engineering work will move forward with the design of Sixth Avenue.

The cost of installing trolley lines is excluded from the plan. The historic trolleys would need to raise the funds required to add trolley lines.

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The award is scheduled to be discussed during next week’s City Council meeting.



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Microsoft promises more AI investments at University of Washington

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Microsoft promises more AI investments at University of Washington


Microsoft will ramp up its investment in the University of Washington.

Brad Smith, the company’s president, made the announcement at a press conference with University of Washington President Robert Jones on Tuesday.

That means hiring more UW graduates as interns at Microsoft, he said.

And he said all students, faculty, and researchers should have access to free, or at least deeply-discounted, AI.

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“ Some of it is compute that Microsoft is donating, and some of it is pursuant to an agreement where, believe me, we give the University of Washington probably the best pricing that anybody’s gonna find anywhere,” Smith said. He assured the small group of reporters present that it would be “many millions of dollars of additional computational resources.”

The announcement today didn’t include any specific numbers.

But Smith said Microsoft has already invested $165 million in the UW over several decades.

He pointed to Jones’ vision to spur “radical collaborations with businesses and communities to advance positive change,” and eliminate “any artificial barriers between the university and the communities it serves.”

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Microsoft’s goal is for AI to help UW researchers solve some of the world’s biggest problems without introducing new ones.

At Tuesday’s announcement, several research students were present to demonstrate how AI supports their work.

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Amelia Keyser-Gibson is an environmental scientist at the UW. She’s using AI to analyze photographs of vines, to find which adapt best to climate change.

It’s a paradox: AI produces carbon emissions. At the same time, it’s also a new tool to help reduce them.

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So how do those things square for Keyser-Gibson?

“ That’s a great question, and honestly, I don’t know the answer to that,” she said. “I’m highly aware that there’s a lot of environmental impact of using AI, but what I can say is that this has allowed us to make research innovations that wouldn’t have been possible otherwise.”

“If we had had to manually annotate every single image that would’ve been an undergrad doing that for hours,” Keyser-Gibson continued. “And we didn’t have the budget. We didn’t have the manpower to do that.”

“AI exists. If we don’t use it as researchers, we’re gonna fall behind.”

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Microsoft reports on its own carbon emissions. But like most AI companies, it doesn’t reveal everything.

That’s one reason another UW student named Zhihan Zhang is using AI to estimate how much energy AI is using.



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