The Super Bowl is in its red era.

The big game will be played between the Kansas City Chiefs and San Francisco 49ers in a rematch of Super Bowl 54.

Patrick Mahomes is seeking his third title in five years to continue a dynasty that started by beating the 49ers in the 2020 championship. This campaign, he made history with tight end Travis Kelce. They passed Tom Brady and Rob Gronkowski for most touchdowns by a duo in the postseason.

Christian McCaffrey is appearing in his first Super Bowl after a historic season where he broke the record for most games with a touchdown. Brock Purdy, Deebo Samuel and Brandon Aiyuk round out the 49ers offense to keep opponents on their toes.

Both defenses have been stalwart throughout the season. The Chiefs will be without defensive lineman Charles Omenihu after the former 49er reportedly tore his ACL in the AFC championship game. Nick Bosa had two sacks in San Francisco’s comeback win in the NFC championship.

The battle begins at 6:30 p.m. on Feb. 11 at Allegiant Stadium in Las Vegas.

Here are the early odds for Super Bowl 58:

Chiefs vs. 49ers odds, moneyline, over/under

The 49ers are favorites to defeat the Chiefs, according to BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023, including the new ESPN BET app and the Fanatics Sportsbook promo code.

• Spread: 49ers (-2)
• Moneyline: 49ers (-130); Chiefs (+110)
• Over/under: 47.5

Not interested in this game? Our guide to NFL betting odds, picks and spreads has you covered with the full slate of playoff action. You can also look ahead to the big game with the best Super Bowl betting promos.

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Super Bowl 58 early odds, predictions and picks

Here are our NFL expert picks based on the early odds for Super Bowl 58:

Tyler Dragon: Chiefs 23, 49ers 20

The 49ers were a top-two team all season long. The combination of Christian McCaffrey, Deebo Samuel, Brandon Aiyuk, George Kittle, Trent Williams and Brock Purdy is tough to beat when they are all on the field healthy. Plus, the 49ers defense is led by all-world linebacker Fred Warner. But the Chiefs have shown us they flip the switch come postseason time. Kansas City’s defense has only allowed more than 20 points once in three postseason games. The Chiefs defense enters the Super Bowl with a playoff-high four takeaways. But above all else, the Chiefs have the best player in the NFL in Patrick Mahomes. Mahomes has picked teams apart with his arm and occasionally hurt defenses with his legs; furthermore, he’s played turnover-free football. All the hype and attention around the Super Bowl won’t faze the Chiefs. The Chiefs have earned Super Bowl berths four times in five seasons. Mahomes is seeking his third Lombardi Trophy. If Mahomes leads the Chiefs to victory, a legitimate case can be made that he’s the greatest quarterback of all time.

Safid Deen: Chiefs 30, 49ers 26

Patrick Mahomes, Andy Reid and the Chiefs entered the postseason with the worst offense they’ve had during their time together in Kansas City. Yet, here they are, in the Super Bowl once again. Sure, Christian McCaffrey and Brock Purdy make the 49ers much more formidable than their last Super Bowl matchup in Miami, but the Chiefs will have enough offense while Chiefs defensive coordinator Steve Spagnuolo will have his fingerprints all over this one. Mahomes wins his third ring and takes another step in his chase of Tom Brady’s seven Super Bowls. 

Victoria Hernandez: Chiefs 28, 49ers 24

The 49ers showed they can perform through adversity by coming back to win the NFC championship. But Patrick Mahomes and Travis Kelce have never been the underdog until this season and are playing with a new sense of hunger. The quarterback quieted criticism that he hadn’t proven himself on the road in the playoffs. And the tight end has broken records while stepping up for the Chiefs’ struggling receiving corps. The 49ers technically have the more well-rounded offense and Nick Bosa, Fred Warner and Dre Greenlaw have done a great job bolstering the defense. But Kansas City’s defense has been a strong suit of theirs this year too. Ultimately, the championship experience and desire to quiet the naysayers will lead to another brick being laid in the Chiefs’ dynasty.

Jordan Mendoza: Chiefs 20, 49ers 17

San Francisco has been one of the most impressive teams all season, and on paper, they should be able to win this game for its first Super Bowl win in nearly 30 years. But the Kansas City defense has certainly been a ruthless force in this Super Bowl run. The Chiefs offense isn’t pretty, but if Patrick Mahomes and Travis Kelce are in sync, they’ll be able to put some points on the board. The Chiefs’ defense can limit Brock Purdy and company and become the first back-to-back champions since the Patriots in 2003-04.

You can view the full list of USA TODAY’s NFL expert predictions here.

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