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San Francisco 49ers vs. Minnesota Vikings: Predictions and latest odds for NFL Week 2

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San Francisco 49ers vs. Minnesota Vikings: Predictions and latest odds for NFL Week 2


NFL Week 2 continues with the highly anticipated clash between the San Francisco 49ers and the Minnesota Vikings at U.S. Bank Stadium on Sunday.

The defending NFC champions dominated their Week 1 game against the New York Jets, securing a 32-19 victory over a team led by Aaron Rodgers, who made his return from an Achilles tendon injury. Quarterback Brock Purdy completed 19 of 29 pass attempts for 231 yards and added 11 rushing yards in Monday’s win. The 49ers achieved the victory without star running back Christian McCaffrey, who didn’t play in a last-minute decision due to a calf injury. The star running back has also been ruled out against the Vikings.

The Minnesota Vikings are coming off a Week 1 victory against the New York Giants. Veteran quarterback Sam Darnold, who left the San Francisco 49ers to sign a one-year deal worth $ 10 million with the Vikings, put up an impressive performance. He completed 19 of 24 passes for 208 yards with two touchdowns and one interception in the 28-6 victory over the Giants.

Here are the latest odds and predictions for the Week 2 matchup between the San Francisco 49ers and the Minnesota Vikings.

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NFL Week 2: San Francisco 49ers vs. Minnesota Vikings odds, moneyline, over/under

The San Francisco 49ers are favorites to defeat the Minnesota Vikings, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

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  • Spread: 49ers (-5.5)
  • Moneyline: 49ers (-230); Vikings (+195)
  • Over/under: 46.5

Not interested in this game? Our guide to NFL betting odds, picks and spreads has you covered with Thursday Night Football odds and Monday Night Football odds.

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NFL Week 2: San Francisco 49ers vs. Minnesota Vikings predictions and picks

ESPN’s Seth Walder: 49ers 31, Vikings 24

Walder writes: “49ers wide receiver Brandon Aiyuk will record 100-plus receiving yards. One bad week, we can chalk up to rust — he had just two catches for 28 yards in the 49ers’ opener. But I don’t see the weak numbers lasting long because Aiyuk is just too good: He was the No. 1 WR in ESPN’s receiver tracking metric’s overall score last season for a reason.”

CBS Sports: 49ers but proceed with caution

Garrett Podell writes: “San Francisco certainly has the matchups to prevail on Sunday and improve to 2-0, but a Sam Darnold and Aaron Jones revenge game with a healthy Justin Jefferson could potentially prove to be tougher than anticipated. Jones ran for 108 rushing yards on 18 carries for a six yards per carry average in the Green Bay Packers’ 24-21 NFC Divisional Round loss at the 49ers in January. Minnesota has enough credible matchups, plus some voodoo (if you believe in superstitious things), when this matchup takes place at U.S. Bank Stadium. Sunday afternoon between these two squads should be top tier programming in the NFL’s 1 p.m. ET Week 2 slate.”

Pickswise: San Francisco 49ers

Kevin Davies writes: “The Vikings had the perfect Week 1. First of all, they were fortunate enough to play the Giants. Daniel Jones looked just as sharp as normal, which is about as sharp as a marble, and Minnesota came away with the 28-6 win. The Vikings defense was putting pressure on Jones all game and that resulted in 5 sacks and 2 interceptions. On offense, Sam Darnold looked fantastic and he was unsurprisingly targeting Justin Jefferson throughout the game. However, we have to put this win into perspective. New York is expected to have one of the worst offenses to go with a severely below-average defense in 2024. It would have been concerning if Minnesota didn’t stomp on the Giants. Now the Vikings have to go from facing Daniel Jones and Malik Nabers to Brock Purdy and Deebo Samuel. The difference is night and day, and San Francisco should demonstrate that by covering the touchdown spread on Sunday.”

Doc Sports: Take the Vikings

Guy Bruhn writes: “The Vikings are relinquishing 6.0 points per game, which has them sitting 1st of all teams in the NFL. They have allowed 0 touchdowns through the air in addition to 166.0 yards/outing, which has them in 16th in the NFL. Minnesota has surrendered a total of 74 yards on the ground. The Vikings defense has taken part in 68 plays, which ranks 25th in the league. They have compiled 2 turnovers on the year.”

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Giants scratch Rafael Devers from lineup with tight hamstring

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Giants scratch Rafael Devers from lineup with tight hamstring


Friday, February 27, 2026 9:48PM

SCOTTSDALE, Ariz. — The San Francisco Giants scratched slugger Rafael Devers from the starting lineup because of a tight hamstring, keeping him out of a spring training game against the Los Angeles Dodgers on Friday.

The three-time All-Star and 2018 World Series champion is starting his first full season with the Giants after they acquired him in a trade with the Boston Red Sox last year.

Devers hit 35 home runs and had 109 RBIs last season, playing 90 games with San Francisco and 73 in Boston. He signed a $313.5 million, 10-year contract in 2023 with the Red Sox.

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He was 20 when he made his major league debut in Boston nine years ago, and he helped them win the World Series the following year.

Devers, who has 235 career homers and 747 RBIs, led Boston in RBIs for five straight seasons and has finished in the top 20 in voting for AL MVP five times.

Copyright © 2026 ESPN Internet Ventures. All rights reserved.



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San Francisco court clerks strike for better staffing, training

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San Francisco court clerks strike for better staffing, training


The people cheering and banging drums on the front steps of San Francisco’s Hall of Justice are usually quietly keeping the calendars and paperwork on track for the city’s courts.

Those court clerks are now hitting the picket lines, citing the need for better staffing and more training. It’s the second time the group has gone on strike since 2024, and this strike may last a lot longer than the last one.

Defense attorneys, prosecutors and judges agree that court clerks are the engines that keep the justice system running. Without them, it all grinds to a slow crawl.

“You all run this ship like the Navy,” District 9 Supervisor Jackie Fielder said to a group of city clerks.

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The strike is essentially a continuation of an averted strike that occurred in October 2025.

“We’re not asking for private jets or unicorns,” Superior Court clerk employee Ben Thompson said. “We’re just asking for effective tools with which we can do our job and training and just more of us.”

Thompson said the training is needed to bring current employees up to speed on occasional changes in laws.

Another big issue is staffing, something that clerks said has been an ongoing issue since October 2024, the last time they went on a one-day strike.

Court management issued their latest statement on Wednesday, in which the court’s executive officer, Brandon Riley, said they have been at an impasse with the union since December.

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The statement also said Riley and his team has been negotiating with the union in good faith. He pointed out the tentative agreement the union came to with the courts in October 2025, but it fell apart when union members rejected it.

California’s superior courts are all funded by the state. In 2024, Sacramento cut back on court money by $97 million statewide due to overall budget concerns.

While there have been efforts to backfill those funds, they’ve never been fully restored.

Inside court on Thursday, the clerk’s office was closed, leaving the public with lots of unanswered questions. Attorneys and bailiffs described a slightly chaotic day in court.

Arraignments were all funneled to one courtroom and most other court procedures were funneled to another one. Most of those procedures were quickly continued.

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At the civil courthouse, while workers rallied outside, a date-stamping machine was set up inside so people could stamp their own documents and place them in locked bins.

Notices were also posted at the family law clinic and small claims courts, noting limited available services while the strike is in progress.

According to a union spokesperson, there has been no date set for negotiations to resume, meaning the courthouse logjams could stretch for days, weeks or more.



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Which San Francisco Giants Prospects Are Real Depth vs. Marketing Names

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Which San Francisco Giants Prospects Are Real Depth vs. Marketing Names


The San Francisco Giants are likely to break camp with one of their top prospects on the 26-man roster. But they’re all getting plenty of work in camp.

The thing is, just because a prospect doesn’t make a 26-man opening day roster doesn’t mean they can’t help a Major League team at some point in the season. Others, for now, are working on developing talent.

In this exercise, five prospects that are part of Major League camp were selected to determine if they’re real depth this season or if they’re marketing names — for now. Marketing names can become real depth before one knows it, such as the first Giants prospect listed.

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Bryce Eldridge: Real Depth

San Francisco Giants Bryce Eldridge | Joe Camporeale-Imagn Images
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Eldridge has nothing left to prove at the minor league level after he was selected in the first round in the 2023 MLB draft. Back then, he was the classic example of a marketing name, one that creates buzz in the organization and with fans.

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But, after more than two years of development and a taste of the Majors, he’s real depth. He’s expected to make the opening day roster and share time at first base and designated hitter with Rafael Devers, one of the game’s most established sluggers.

On Wednesday, he hit his first spring training home run, one of three in the 13-12 loss to the Milwaukee Brewers.

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Blake Tidwell: Real Depth

Tennessee pitcher Blake Tidwell | Brianna Paciorka/News Sentinel / USA TODAY NETWORK

Tidwell was acquired from the New York Mets in July in the Tyler Rogers trade. He only pitched in four games for the Mets, so he still has prospect status. But that MLB service time, combined with his early impressions in camp, make him real depth for a team that only has one or two spots available on the pitching staff.

Tidwell may not make the team out of camp for opening day. But he’s one of those prospects that could make his way to San Francisco during the season due to injury or underperformance. It’s an example of using the time in spring training wisely and paving the way for a future promotion.

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Will Bednar: Real Depth

Mississippi St. Bulldogs pitcher Will Bednar. | Steven Branscombe-Imagn Images
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The Giants have been waiting for their first-round pick in the 2021 MLB draft to pay off, and this might be the year that Will Bednar finally makes the jump to the Majors. He’s in Major League camp and he’s been converted into a reliever in the past couple of seasons.

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He went 2-3 with a 5.68 ERA in 38 games, his full season as a reliever. But he’s impressed the new coaching staff during camp and there’s enough buzz around him to consider him a potential call-up during the season. He’s in his fifth professional season so the Rule 5 draft is a consideration this coming offseason.

Parks Harber: Marketing Name

For now, the young third baseman is going to create a lot of buzz in the farm system in 2026, but he isn’t a threat to anyone’s job yet. Picked up in the Camilo Doval trade, he only has 102 minor league games under his belt after he was signed as an undrafted free agent by the New York Yankees. He got his first spring training hit on Wednesday. His career slash of .312/.413/.528 is encouraging but he hasn’t played higher than High-A Eugene.

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Bo Davidson: Marketing Name

San Francisco Giants left fielder Bo Davidson. | Rick Scuteri-Imagn Images
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The Giants signed Davidson as an undrafted free agent and he’s starting to generate real buzz in spring training as a non-roster invitee. He’s not quite real depth yet because he has yet to play above Double-A Richmond. But the way he’s playing in the spring he should be at Sacramento sometime this season, which puts him in the position to be real depth.

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He’s hit well at every stop, but he showed off more power than ever last season. He hit a career-best 18 home runs and 70 RBI as he slashed .281/.376/.468. He played 42 games at Richmond last season.




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