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San Francisco 49ers at Tampa Bay Buccaneers: Predictions, picks and odds for NFL Week 10 game

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San Francisco 49ers at Tampa Bay Buccaneers: Predictions, picks and odds for NFL Week 10 game


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The San Francisco 49ers and Tampa Bay Buccaneers find themselves in very similar situations heading into Week 10. Both teams have four wins, are currently in second-place in their divisions, and have suffered tough losses to their divisional foes in first. They’ve also both suffered a myriad of injuries to their star skill position players and both teams have taken losses at the hands of the Kansas City Chiefs.

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There is one key difference between these teams though. The 49ers are coming off a bye, while the Buccaneers just played on Monday Night Football. The 49ers should be well-rested, while the Bucs might be more banged up than usual, getting one fewer day to recover.

With both teams missing key players, like Christian McCaffrey and Brandon Aiyuk on the 49ers’ side as well as Mike Evans and Chris Godwin on the Bucs’ side, you’d think both teams would be struggling on offense. However, both teams rank top-ten in points per play.

Here are our experts’ predictions for this Week 10 showdown.

PROP TALK: These are the best prop bets for NFL games this week 

Buccaneers vs. 49ers odds, moneyline, over/under

The 49ers are favorites to defeat the Buccaneers, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

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  • Spread: 49ers (-5.5)
  • Moneyline: 49ers (-250); Buccaneers (+200)
  • Over/under: 50.5

Not interested in this game? Our guide to NFL betting odds, picks and spreads has you covered with Thursday Night Football odds and Monday Night Football odds.

New to sports betting? USA TODAY readers can claim exclusive promos and bonus codes with the best online sportsbooks and sports betting sites.

FEELING LUCKY? Here are the best parlay bets and odds for NFL games this week 

NFL Week 10 odds, predictions and picks

Ravens vs. Bengals | Panthers vs. Giants | Bears vs. Patriots | Colts vs. Bills | Jaguars vs. Vikings | Chiefs vs. Broncos | Saints vs. Falcons | Buccaneers vs. 49ers | Commanders vs. Steelers | Chargers vs. Titans | Cardinals vs. Jets | Cowboys vs. Eagles | Texans vs. Lions | Rams vs. Dolphins

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Lorenzo Reyes: 49ers 28, Buccaneers 20

The Buccaneers play up to elite competition, with the top strength of victory (.647) — or the combined winning percentage of teams Tampa has defeated. The Bucs, in fact, are the only team above .600 in that stat. But the 49ers are coming off a bye week, and one they needed to heal up. Frankly, I can see this going both ways and would likely look elsewhere for a safer play, but given the extra rest — and the fact that Tampa has a slightly shorter week after playing Monday night — I’ll cautiously back the Niners.

Tyler Dragon: 49ers 25, Bucs 21

Will Christian McCaffrey make his season debut this week? San Francisco is coming off a Week 9 bye. While the Bucs are playing on a short week. The 49ers know they need to start performing better if they want to reclaim top status in the NFC West. San Francisco should win this game whether McCaffrey plays or not.

Richard Morin: 49ers 28, Buccaneers 27

San Francisco desperately needs to get going, but it won’t be an easy task on the road in Tampa Bay. I think the 49ers pull out the win, but the 5.5-point spread is a bit much for me.

Jordan Mendoza: 49ers 23, Buccaneers 16

Could Christian McCaffrey actually play? He’ll make an immediate difference and get San Francisco back to being solidified contenders.



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San Francisco, CA

SF scientists build robotic storm samplers to track pollutants before they reach the Bay

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SF scientists build robotic storm samplers to track pollutants before they reach the Bay


SAN FRANCISCO (KGO) — Environmental Scientist Kayli Paterson from the San Francisco Estuary Institute is hitting the road with colleague David Peterson and a trunk full of water sampling robots.

“Yeah, I think the max we’ve ever done was five. But the sites are very close together. Oh, there it is. Hopefully it samples well,” says Paterson as she turns the mobile sampling lab onto a private oak-lined road.

They’re closing in on a watershed creek flowing through the hillsides near the San Andreas Lake reservoir, west of Highway 280 in Millbrae, part of the larger watershed that eventually drains into San Francisco Bay.

“So, we’ve got our sampler. Look at the battery. Hook that up, red and black. This is a 12-volt lithium battery, and it powers our sampler for probably about six to seven days,” she explains, showing off a self-contained unit miniaturized into a portable case.

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The black cases are their latest innovation in stormwater science. Robotic samplers anchor in key sections of the watershed to monitor not only flow, but also the chemicals and pollutants washing downstream toward the Bay.

“And this is a front-line pollution sampler. It’s getting the stormwater before it enters the Bay. And so, we want to know what’s coming into the Bay and getting these samplers out there in more locations will give us a better idea of where we might have issues, where a hotspot is, or maybe a previously unknown contaminant,” says Paterson.

“It’s important to get out that fast,” her colleague David Peterson adds. “You know, in these storms as they’re happening, because the water is picking up pollutants in real time, and we need to be there to capture them.”

When we first met Peterson several years ago, he and another Estuary Institute team were sampling water along the Bay shoreline by hand, a technique that’s still valuable. But to cover more ground, Kayli and a group of collaborators began developing the robotic samplers over recent storm seasons.

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Kayli and David start by chaining the unit itself to a tree near the creek bank. The system employs remote-controlled pumps that draw samples from the creek and store them in onboard containers. The software controlling the volume and frequency can be operated from a phone app.

MORE: New study of San Francisco Bay fish confirms concentrations of PFAS aka ‘forever chemicals’

One of the key targets in this study is a group of so-called “forever chemicals” known as PFAS, synthetic compounds that persist in the environment and have been detected in widespread areas of the Bay.

“And we capture samples and send them off to analytics labs across the country. Typically, universities or private labs will process these for us,” Peterson explains.

For these two stormwater detectives, it’s a mission that requires a combination of speed and patience**, chasing flowing water** through creeks and storm drains, sampling as they go.

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“So, we’re looking for areas – the point of this is to do source control. Ultimately, we want to be able to trace this back to a possible source,” says Kayli Paterson.

And potentially prevent a source of toxic pollution from reaching San Francisco Bay and our Bay Area ecosystem.

More than a dozen of the robots were given names in a special contest, including the Big Sipper and the Tubeinator.

Copyright © 2026 KGO-TV. All Rights Reserved.



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Floats for San Francisco Chinese New Year Parade get finishing touches

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Floats for San Francisco Chinese New Year Parade get finishing touches


SAN FRANCISCO (KGO) — ABC7 Eyewitness News got a sneak peak as crews put the finishing touches on the floats you’ll see at Saturday’s San Francisco Chinese New Year Festival and Parade.

Since it’s the year of the fire horse, you’ll see a lot of horses and fire symbolism on the floats, housed at Pier 19.

“So Year of the Horse, it’s energy, it’s passion, it’s momentum so a lot of things that we’re really hoping to embody in the new year,” said Stephanie Mufson, owner of San Francisco-based The Parade Guys, which designs and constructs the floats.

She said they’ve been building them for about three months, with the designs starting in November.

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“We’re in the home stretch,” she said. “We’ve got a couple of days left and we’ve got a nice little team that’s cranking out all the finishing work that needs to go into it.”

Derrick Shavers was sanding some wood that will be painted and become cherry blossom trees on a float.

“It’s exciting,” Shavers said. “I look forward to coming every year and just creating and making things shine and sparkle.”

Bon was painting mountains for a float, making sure everything is perfect in time for the parade.

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“It’s one of the few parades that actually happens at night still,” Bon said. “So we got to make sure all the lighting is in check, and people are safe on the float. It’s all in the details, just for it to walk by you for 10 seconds.”

Ten seconds that bring so much joy to those watching the parade.

Here’s how you can watch the parade on ABC7 Eyewitness News on Saturday, March 7.

Coverage starts at 5 p.m. wherever you stream ABC7.

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SF Chinese New Year Parade 2026: How to watch ABC7 Eyewitness News live coverage


If you’re on the ABC7 News app, click here to watch live

Copyright © 2026 KGO-TV. All Rights Reserved.



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Celebrated San Francisco historic landmark, the Huntington Hotel officially reopens

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Celebrated San Francisco historic landmark, the Huntington Hotel officially reopens


SAN FRANCISCO (KGO) — First opened as apartments in 1922 and converted into a hotel two years later, the Huntington was once a playground for socialites and Hollywood stars.

It shut its doors in 2020 due to the COVID-19 pandemic and remained shuttered until this week, following new owners and a million-dollar, top-to-bottom renovation.

A ribbon-cutting ceremony was held for The Huntington Hotel in San Francisco’s Nob Hill neighborhood Monday.

The hotel officially reopened on Sunday.

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Mayor Daniel Lurie attended the celebration for the hotel on California Street.

“This is another sign that San Francisco is on the rise, when you have major institutions and major hotels reopening,” Lurie said. “We’re seeing it in Union Square. We’re seeing it now up here on Nob Hill. This is an exciting moment for San Francisco.”

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The hotel, known for its iconic sign, will be restoring the landmark sign to its former glory.

Many say it’s a symbol of what’s going on in San Francisco.

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“It came to symbolize San Francisco’s decline during COVID when it shut and it now, I think, symbolizes San Francisco’s rebirth,” said Greg Flynn, Flynn Group Founder, Chairman, and CEO. “It’s sort of the perfect symbol of it because it’s coming back better than it ever was.”

Alex Bastian, President and CEO of the Hotel Council of San Francisco, said hotel occupancy rates are up in 2024.

“Our data team crunched the numbers, and the four-week rolling hotel occupancy rate for San Francisco Bay Area hotels is 55.1 percent as of January 17 of this year. Compare that to January 17 of 2021, during the pandemi,c when it was 13.1 percent.”

Of course, the Super Bowl helped.

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“There’s no marketing campaign better than what we achieved as San Franciscans,” Bastian said. “The mayor and his team really elevated the game. They did an incredible job. We are so fortunate, as a city, because so many came here and they left their hearts here in San Francisco.”

Eyewitness News wasn’t allowed to gather video of the hotel’s features, but the hotel provided renderings of a sample room.

Matthew de Quillien, The Huntington Hotel General Manager, said the hotel has 143 rooms, many of them suites. Also, the Nob Hill Spa, Arabella’s Cocktail Salo,n and a reopening of The Big Four Restaurant, featuring its famous chicken pot pie.

“Our owner was able to find the original recipe from the 70’s and we remastered it and we’re … serving it to our guests,” de Quillien said.

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He said rates range from $600 a night to $7,000 a night for its Presidential suite.

The restaurant opens to the public on March 17.


If you’re on the ABC7 News app, click here to watch live

Copyright © 2026 KGO-TV. All Rights Reserved.

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