A battle of SEC rivals square off in the third weekend of the 2024 college football season as No. 16 LSU looks to get a leg-up in the conference standings against an undefeated South Carolina.

Carolina is already up a win in the SEC after dominating Kentucky in a game that saw LaNorris Sellers throw for 2 touchdowns and Raheim Sanders rush for a third.

LSU recovered from its opening loss to USC with a victory over Nicholls, although the FCS challenger did keep the game close until the third quarter.

Let’s take a look at the early betting odds and predictions for LSU vs. South Carolina this week.

Lines are courtesy of FanDuel Sportsbook

LSU: -7.5 (-102)
South Carolina: +7.5 (-120)

LSU to win: -265
South Carolina to win: +215

Over 52.5 points: -110
Under 52.5 points: -110

FPI picks: LSU 51% to win

+ LSU is 5-2 against the spread in its last 7 games against South Carolina

+ Total went under in South Carolina’s last 5 games

+ Total went over in 5 of LSU’s last road games

+ Gamecocks are 4-1 against the spread in last 5 games in September

+ Total went over in LSU’s last 5 games against SEC teams

+ Total went under in 4 of South Carolina’s last 5 home games

+ LSU is 1-4 against the spread in last 5 September game

+ Total went under in 5 of Gamecocks’ last 6 games against SEC teams

South Carolina: 56 percent of bettors suggest the Gamecocks will win in a upset or keep the game within the line

LSU: 44 percent of wagers predict the Tigers will win the game and cover the spread

Our pick: LSU -7.5, Over 52.5

When: Sat., Sept. 14
Time: 12 p.m. Eastern
TV: ABC network

Game odds refresh periodically and are subject to change.

If you or someone you know has a gambling problem and wants help, please call 1-800-GAMBLER.

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