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College Football Playoff 2025 bracket prediction: USC enters top 12, Oklahoma falls out

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College Football Playoff 2025 bracket prediction: USC enters top 12, Oklahoma falls out


USC made a statement with Saturday’s win over Michigan, and can do so again at Notre Dame next week. Luke Hales / Getty Images

Welcome to my College Football Playoff projections, which are a weekly feature through season’s end. I will update and adjust them each week after each Saturday’s results. Austin Mock will have his computer-based projections, which will differ greatly from my opinion-based selections.

A couple of decades ago, when I covered Major League Baseball, a general manager told me that April is about reasons and May is about results. The same theory applies to college football in September and October. We found out which teams are capable of competing for the College Football Playoff in the first month. Now, it’s about proving it.

Top-ranked Ohio State passed another test with a resounding win at No. 17 Illinois. Miami was off, but the Hurricanes are there with the Buckeyes. The most impressive team this week — and perhaps the best win of the season — came from No. 7 Indiana beating No. 3 Oregon 30-20 in Eugene. Any questions raised about Indiana’s CFP viability from last year have no bearing this year. The Hoosiers are better in every area this fall and proved it at Oregon.

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The SEC had some upheaval, with Texas popping previously unbeaten Oklahoma at the Cotton Bowl and Alabama outlasting Missouri in Columbia. The loss knocks the Sooners out of the CFP field — for now — and the Tigers stay just on the outside. Ole Miss survived against Washington State, 24-21, in a win that felt more like a loss. The Rebels slip a few spots as a penalty but can earn their way back into a bye this week should they win at Georgia. I’m not sure if Texas A&M is an SEC championship team or merely really good. We’ll know in a few weeks with games against LSU and Missouri.

Oklahoma’s Red River loss opens up a slot, and USC’s dismantling of Michigan with nearly 500 yards suggests the Trojans are the nation’s most overlooked team. They get a chance to prove if they belong in the CFP pool this week at Notre Dame.

Should these first-round matchups come to fruition, Georgia visiting Oregon and former defensive coordinator Dan Lanning at Autzen Stadium would have ABC salivating. One of the great rivalries would have its biggest stage with LSU visiting Ole Miss. USF heads to Alabama, and USC at Texas Tech rounds out the field.

Five upcoming games with CFP significance: Ole Miss at Georgia (3:30 p.m. ET, ABC); Texas Tech at Arizona State (4 p.m. ET, Fox); USC at Notre Dame (7:30 p.m. ET, NBC); Tennessee at Alabama (7:30 p.m. ET, ABC); Utah at BYU (8 p.m. ET, ESPN2)

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Watch Oklahoma LB Kendal Daniels Recap the Loss to Texas

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Watch Oklahoma LB Kendal Daniels Recap the Loss to Texas


RYAN CHAPMAN

Ryan is co-publisher at Sooners On SI and covers a number of sports in and around Norman and Oklahoma City.

Working both as a journalist and a sports talk radio host, Ryan has covered the Oklahoma Sooners, the Oklahoma City Thunder, the United States Men’s National Soccer Team, the Oklahoma City Energy and more.

Since 2019, Ryan has simultaneously pursued a career as both a writer and a sports talk radio host, working for the Flagship for Oklahoma sports, 107.7 The Franchise, as well as AllSooners.com.

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Ryan serves as a contributor to The Franchise’s website, TheFranchiseOK.com, which was recognized as having the “Best Website” in 2022 by the Oklahoma Association of Broadcasters.

Ryan holds an associate’s degree in Journalism from Oklahoma City Community College in Oklahoma City, OK. 



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Houston vs Oklahoma State Prediction, Picks & Odds for Today — College Football Week 7

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Houston vs Oklahoma State Prediction, Picks & Odds for Today — College Football Week 7


Rosales’ prediction: If Conner Weigman plays, Houston looks set to extend Oklahoma State’s woes with another dominant victory.

Oct 11, 2025 • 09:17 ET

• 4 min read

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After dropping their first game of the season, the Houston Cougars aim to bounce back as they take on the Oklahoma State Cowboys.

It’s been a rough year for the Cowboys, who have already parted ways with their head coach and are now on a four-game losing streak.

See my Houston vs. Oklahoma State predictions for the top wager, plus all our college football picks for this Big 12 showdown on Saturday, October 11.

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Houston vs Oklahoma State prediction

Houston vs Oklahoma State best bet: Houston -14.5 (-110)

Normally, I’d steer clear of a spread that big, but there’s no redeeming qualities coming out of this Oklahoma State team.

They have been crushed in back-to-back losses to Baylor (45-27) and last week to Arizona (41-13). In their four straight losses, only Tulsa failed to blow them out, winning 19-12.

They’re also down quarterback Zane Flores, who hurt his shoulder in the loss to Arizona.

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That leaves them with freshman Banks Bowen, and Sam Jackson, who had converted to wide receiver last year while at Auburn. He replaced Flores against Arizona and threw for 27 yards on 3-for-6 passing.

Houston’s pivot problem is more encouraging, as Conner Weigman went into concussion protocol after leaving their 35-11 loss to Texas Tech in the second quarter.

After building a solid 4-0 mark, Weigman’s injury derailed the Cougars’ litmus test against its first ranked opponent on the year. He had thrown for 93 yards and a score before leaving the game, and Houston didn’t score another point.

Assuming he does play, he’ll lead a Houston Cougars offense averaging 27.2 points per game. Oklahoma State is averaging a paltry 16.4 points per contest, and their defense is 130th or worse in total yards and passing yards per game, while ranking 112th against the rush, at 179.4 per contest.

Houston vs Oklahoma State same-game parlay

During this current four-game losing slide, Oklahoma State has trailed by at least seven points in three of them. The only game they came out even was against Baylor, tied 7-7 after the first 15 minutes.

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In Houston’s four wins, they came out of the opening quarter with at least a seven-point lead twice, and in a scoreless draw in another.

They should be in position to get ahead in this one on Saturday.

Houston vs Oklahoma State SGP

  • Houston -14.5
  • Under 46.5
  • Houston -3.5 first quarter spread

Houston vs Oklahoma State game predictions

Houston vs Oklahoma State moneyline prediction

Houston ML (-620 at FanDuel)

I don’t see any way that Houston loses this game, even if Weigman were to sit out. So in that sense, a wager on the moneyline wouldn’t be the worst idea, but close, with little juice to make it worth your while.

A wager on OKST at +460? You might enjoy burning your money more than betting on the Cowboys.

Houston vs Oklahoma State spread prediction

Houston -14.5 (-110 at FanDuel)

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If Conner Weigman suits up, he’ll take charge of a Houston offense that’s putting up 27.2 points per game. In contrast, Oklahoma State is struggling offensively, averaging just 16.4 points per game.

Defensively, the Cowboys rank 130th or worse in both total and passing yards allowed per game, and they’re 112th against the run, giving up 179.4 rushing yards per contest.

Houston vs Oklahoma State Over/Under prediction

Under 46.5 points (-115 at FanDuel)

I don’t think this is a game where Houston wants to flex.

More than anything, I think they want to get out big early, perhaps open it up to the backups and get out of Stillwater without any serious injuries, as they have Arizona and no. 21 Arizona State on the horizon.

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The Cowboys’ offense is in shambles, and their QB options don’t exactly instill some kind of offensive boost.

Their inability to put up points brings this score Under the total.

Houston vs Oklahoma State odds

  • Spread: Houston -14.5 (-110) | Oklahoma State +14.5 (-110)
  • Moneyline: Houston -620 | Oklahoma State +460
  • Over/Under: Over 46.5 (-115) | Under 46.5 (-105)

Houston vs Oklahoma State trend to know

Oklahoma State has failed to cover the spread in nine of its last 10 games. Find more college football betting trends for Houston vs Oklahoma State.

How to watch Houston vs Oklahoma State

Location Boone Pickens Stadium, Stillwater, OK
Date Saturday, October 11, 2025
Kickoff 12:00 p.m. ET
TV TNT

Houston vs Oklahoma State latest injuries

Houston vs Oklahoma State weather

Monitor gametime conditions with our College football weather info.

Odds are correct at the time of publishing and are subject to change.
Not intended for use in MA.
Affiliate Disclosure: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links.

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OK State on SI’s Score Predictions: Oklahoma State vs. Houston

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OK State on SI’s Score Predictions: Oklahoma State vs. Houston


Oklahoma State has only one win this season, and this could be its best chance to get another until 2026.

On Saturday, OSU will host Houston in each team’s third Big 12 contest. With the Cowboys still searching for their first conference win since 2023, they will have their work cut out against a 4-1 Cougars squad.

Coming off a 35-11 loss against Texas Tech to end their undefeated start to the year, the Cougars will be heading to Stillwater with a bounce-back performance on their mind. After Texas Tech broke Houston’s four-game winning streak last week, OSU will be hoping to break its own four-game losing streak in its third game since firing Mike Gundy.

OK State on SI’s score predictions for Oklahoma State-Houston:

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Houston 45 Oklahoma State 13

OSU is in its worst position in decades, and this game should erase all doubt about where the Cowboys stand. While Houston hasn’t scored more than 36 points in a game thus far, OSU’s defense continues to get depleted by the transfer portal and has given up at least 40 in consecutive games.

For OSU to stay in this one, it will need Sam Jackson V to have a spectacular day at quarterback, but even that might not be enough to save the Pokes from their awful defense.

Oklahoma State 27 Houston 21 

My optimism must remain strong as the Cowboys roll out their third starting quarterback of the season.  Sam Jackson V was a wideout coming into the year and will now look to salvage a disastrous season. The Pokes are a two-touchdown underdog, but stranger things have happened this season.  We have a wide receiver starting a Big 12 football game at quarterback.  Jackson V rushes for a pair of scores and single-handedly wills the Cowboys to victory.

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Houston 24, Oklahoma State 20

OSU has continued its streak of bad luck with portal departures and injuries that have occurred. Quarterback Conner Weigman will be difficult for the Cowboys to stop, and we haven’t seen the Cowboys respond well to high-scoring teams. Additionally, if the Cowboys are without their second-string quarterback Zane Flores, that could be yet another issue for their offense production. The Cowboys will have to lean on Trent Howland and Rodney Fields Jr. to move the ball, and I don’t believe it will be enough, just like it hasn’t these past couple of weeks.



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