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Fujifilm Invests Additional $1.2 Billion to Expand its North Carolina CDMO

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Fujifilm Invests Additional .2 Billion to Expand its North Carolina CDMO


Fujifilm invested $1.2 billion in its large-scale cell culture CDMO business to further expand the planned Fujifilm Diosynth Biotechnologies end-to-end bio-manufacturing facility in Holly Springs, NC. The total investment in the facility now totals over $3.2 billion.

The new investment will add 8 x 20,000 liters mammalian cell culture bioreactors by 2028, to the already planned 8 x 20,000 L for bulk drug substance as part of the initial investment. This new facility allows for flexibility to expand with additional bioreactors to accommodate new projects to meet the emerging needs of partners, and upon completion will make the site one of the largest cell culture biopharmaceutical CDMO facilities in North America, according to Fujifilm officials.

Ability to construct identical large-scale production facilities 

Through Fujifilm Diosynth Biotechnologies’ modular production model, KojoXTM, the expansion enables the company to construct identical large-scale production facilities in U.S. and Europe to ensure that customers can seamlessly integrate drug manufacturing production regardless of location, noted Teiichi Goto, president and CEO, representative director, Fujifilm.

Based on the Evaluate Pharma World Preview, the antibody drug market is expected to grow at an annual rate of eight percent through 2030 due to increasing demands for conventional antibody drugs as well as the expansion of antibody drug conjugates (ADCs) and novel antibody drugs using bispecific antibodies.

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“Securing adequate capacity to support market demands is a cornerstone of our Partners for Life strategy and essential to helping our partners bring life-impacting medicines to patients,” said Lars Petersen, president and CEO, Fujifilm Diosynth Biotechnologies.

In line with the overall design and construction of the Holly Springs facility, the new investment will incorporate sustainability initiatives that contribute to net-zero operations. All energy needs for operations is expected to be 100% offset through the use of renewable landfill gas, onsite solar and the 125,000 MWh of annual sustainable solar energy from a virtual power purchase agreement.

Additional sustainability goals for water and waste reduction align with Fujifilm’s Sustainable Value Plan 2030, and the campus is on track to achieve LEED Gold Certification with initiatives that include diverting 90% of construction waste from landfill, additional rooftop solar electricity, installation of heat recovery chiller systems to maximize efficiency between boilers and the chilled water system, use of low embodied carbon concrete utilizing waste fly ash which delivers a 10% reduction in carbon emissions compared to standard cement, and installing ultra-low Nitrogen Oxide boilers, leading to a 50% reduction in nitrogen emissions, pointed out Petersen.

For related articles see GEN: “$2B or Not $2B: Fujifilm Diosynth Breaks Ground on NC Cell Culture Facility” and “Fujifilm Diosnynth Plans $2B Cell Culture Facility in Holly Springs, NC.”

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NC Made: Durham’s Old Hillside Bourbon toasts Black heritage one bottle at a time

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NC Made: Durham’s Old Hillside Bourbon toasts Black heritage one bottle at a time


DURHAM, N.C. (WTVD) — Bourbon is more than a business for Jesse Carpenter — it’s a tribute to the city that shaped him.

“This is Durham. This is where I’m from. This is where I grew up,” said Carpenter, Chief Product Officer of Old Hillside Bourbon.

The company he co-founded with childhood friends takes its name and identity from one of Durham’s most iconic institutions-Hillside High School, one of the oldest historically Black high schools in the nation.

“We graduated Class of 1993 from Hillside High School,” Carpenter said. “Concord and Lawson Street. It’s the old Hillside.”

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The idea took root during the pandemic when Carpenter proposed starting a bourbon company to those same friends.

“I had an idea to start a bourbon company, and they were on board,” he said. “Friends from 30 years ago, and now we’re doing this business together. It’s awesome.”

From 300 Cases to 10,000

What began as a pandemic-era idea has evolved into a rapidly growing business.

In its inaugural year, Old Hillside distributed 300 cases; this year, the company anticipates 10,000. The bourbon also earned Best in Show at the 2023 TAG Global Spirits Awards, impressing even the most discerning craft bourbon critics.

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“Let me focus on the aroma — layers of oak, vanilla,” one reviewer commented on the Bourbon Banter YouTube channel, concluding with, “I think it’s a great taste.”

SEE MORE NC MADE STORIES

A Bottle Full of Stories

Beyond its flavor, Old Hillside stands out for the history embedded in its label. Each vintage pays homage to a chapter of Black American history that might otherwise remain overlooked.

The inaugural bottle features a photo of the old Hillside High building, symbolizing the school’s deep community ties. A second flavor pays tribute to the African American jockeys who dominated the Kentucky Derby before the Jim Crow era effectively pushed them out of the sport. The company’s latest release honors the Harlem Hellfighters, the renowned all-Black military unit that served with distinction in World War I.

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It’s a storytelling approach that Carpenter and his team are actively working to spread across North Carolina. Brand ambassadors Corey Carpenter and Amire Schealey are on the front lines of that effort.

“More bars and restaurants — tackling different markets,” said Corey Carpenter. Schealey added that the team is “setting up tastings at different ABC boards to build up our brand and presence around the state of North Carolina.”

Like many acclaimed bourbons, Old Hillside is distilled and bottled in Kentucky. But its founders are quick to point out where its true spirit comes from.

“Old Hillside is a lifestyle,” Jesse Carpenter said. “Not just a school-friendship and camaraderie. That’s what we do.”

SEE ALSO | NC Made: Raleigh jewelry brand AnnaBanana grows from UNC dorm room to statewide success

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State and local leaders discuss ‘child-care crisis’ in NC

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State and local leaders discuss ‘child-care crisis’ in NC


DURHAM, N.C. (WTVD) — State and local leaders gathered in Durham on Thursday to discuss how they say North Carolina’s ‘child-care crisis’ is taking a toll on our communities.

“We’re demanding recognition,” former childcare provider DeeDee Fields said. “We want fair compensation. We want health protections and a retirement pathway for the workforce that makes all the work possible.”

Childcare is one of the biggest expenses North Carolinians face, with infant care more costly than in-state college tuition per year, according to data. Childcare for a four-year-old costs nearly $8,000 a year.

Since 2020, North Carolina has seen a record loss of licensed childcare programs. Durham County, for example, experienced a 14% drop.

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“I think a lot of people are making these tough choices about what makes the most sense for their family,” Nylah Jimerson said.

Jimerson used to work as a nanny before she became a parent. She’s one of more than a quarter of parents in North Carolina who left the workforce to stay home to care for children.

As North Carolina is the only state without a new budget, childcare is top of mind for State Sen. Sophia Chitlik, who co-authored a package of bills that aims to better support the industry, including making childcare more affordable.

“The ‘Child Care Omnibus’ is part of a series of bills that have budget requirements and budget asks in them,” Chitlik said. “But we’re not going to know until we get a state budget. The most urgent and important thing, in addition to those subsidies, is raising the subsidy floor … so I hope that there is bipartisan consensus that would be worked out in a state budget.”

North Carolina could remain without a budget until the legislature is back in session in April.

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“We have got to do something about childcare,” Sen. Natalie Murdock said. “We shouldn’t be in this position … we have to have a sustainable model and program because it’s about our children.”

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Lawmakers discuss solutions to solving a 'child care crisis' in NC

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Lawmakers discuss solutions to solving a 'child care crisis' in NC


State and local leaders are meeting in Durham to talk about solutions to what lawmakers call a “child care crisis” in North Carolina. There will also be local leaders discussing other solutions to improve child care services and make them more affordable.



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