Science
Why do we get side effects from vaccines? Experts say that means it’s working
The cooling sensation of an alcohol swab in your higher bicep is a cue for what’s about to come back subsequent: the injection of a needle that delivers a dose of vaccine.
Greater than 69% of Individuals have acquired at the very least one dose of a COVID-19 vaccine, and as a bandage is utilized to your arm, you’re a part of the membership.
Whether or not you’re getting your first shot, a second dose or a booster, you’re more likely to expertise some uncomfortable side effects.
They might be inconvenient, and so they definitely might be uncomfortable. However immunologists and virologists say they’re to be anticipated. And also you may even welcome them.
Right here’s why, and what it is best to count on if in case you have a date with a needle.
Why do vaccines trigger uncomfortable side effects?
To place it merely, the uncomfortable side effects are a organic signal that the vaccine is working.
All three of the COVID-19 vaccines out there within the U.S. successfully work in the identical manner, mentioned Dr. David Pleasure, an infectious illness specialist at UC San Diego.
The vaccines include genetic directions for making copies of the coronavirus’ spike protein. The Pfizer-BioNTech and Moderna vaccines use mRNA to hold the directions, and the Johnson & Johnson shot employs a disabled adenovirus, which is innocent.
As soon as the directions are delivered, it’s as much as your cells to do the work. The pretend spike proteins can’t do any injury since they’re not linked to precise coronaviruses. However your physique will detect them and suppose an an infection is underway, prompting the immune system to swing into motion, Pleasure mentioned. You’ll be able to consider it as a coaching run.
The immune response is available in two elements. First, the innate immune system is alerted to the arrival of attainable viruses or different pathogens in your physique, mentioned Dr. Peter Hotez, co-director of the Texas Kids’s Hospital Middle for Vaccine Growth. Then the adaptive immune system produces antibodies that may reply appropriately to the intruder — and, if needed sooner or later, to an precise encounter with the virus.
The uncomfortable side effects you’re feeling are a pure a part of your immune system’s response to the vaccine’s viral payload.
What’s regular and what’s not?
Negative effects to a COVID-19 vaccine are generally delicate and generally extra intense, like a foul chilly or a case of the flu. Both manner, they shouldn’t final greater than 72 hours.
The commonest uncomfortable side effects are low-grade fever, fatigue, muscle ache, headache, chills and nausea, based on the Facilities for Illness Management and Prevention. Short-term soreness on the injection website can be frequent. As Dr. George Rutherford, professor of epidemiology and biostatistics at UC San Francisco, places it: You simply acquired caught with a needle; vaccine or not, that’s going to harm.
The clinic or pharmacy the place you get your shot will ask you to hold round for 15 or half-hour after after your injection, to allow them to monitor you for uncommon however critical reactions, resembling an acute allergic response that requires epinephrine.
When you get residence, you’ll be able to take over-the-counter ache relievers resembling Tylenol or Advil. (Don’t take them earlier than your shot as a result of that may dampen the vaccine’s effectiveness.) Past permitting your physique to relaxation, there’s not a lot else you are able to do whereas using out regular uncomfortable side effects.
In uncommon circumstances, folks — largely teenage boys and younger males — expertise myocarditis (irritation of the center muscle) or pericarditis (irritation of the tissue that surrounds the center) within the week after getting a shot. Signs embrace chest ache, shortness of breath and emotions of getting a fast-beating or pounding coronary heart. If this occurs to you, search medical consideration instantly. Most often, the situations are simply handled with medication and relaxation.
A really small variety of folks — largely girls beneath age 50 — who get the Johnson & Johnson vaccine might expertise a critical facet impact known as thrombosis with thrombocytopenia syndrome, or TTS. Signs embrace chest ache, leg swelling, shortness of breath, complications and stomach ache. In case you develop these signs after getting a J&J shot, see a health care provider instantly.
Some other signs that usually aren’t related to vaccines ought to be monitored. In the event that they don’t enhance, name your physician or go to the emergency room.
Does a scarcity of uncomfortable side effects imply the vaccine isn’t working?
No. Some “fortunate folks” expertise few or no uncomfortable side effects. However that doesn’t imply their immune system isn’t correctly responding.
Hotez mentioned there isn’t a correlation between the severity of uncomfortable side effects and the energy of the immune response. In different phrases, having no uncomfortable side effects doesn’t imply the vaccine is just not working, and having extra uncomfortable side effects doesn’t imply it’s working higher.
Antibody assessments can present how nicely your immune system has responded to a vaccine, however Pleasure mentioned people who find themselves immunocompromised are the one ones who want to fret about that. For most individuals, there’s little likelihood the vaccine will fail to stimulate an immune response. Speak to your physician for those who’re not sure.
Different issues to learn about vaccines
- It’s unimaginable so that you can get coronavirus from the vaccines.
- Likewise, for those who’re feeling sick after getting a vaccine, you don’t want to fret about being contagious and spreading COVID-19 to anybody else.
- Booster photographs are needed, Hotez mentioned. Vaccinations are virtually at all times given in a collection, and the COVID-19 vaccine is popping out to be no completely different. For the very best immune response, it’s important to proceed coaching your system, he mentioned.
- You may have the choice of getting a distinct sort of vaccine on your booster shot than you probably did on your preliminary immunization. Whether or not you stick to the identical model or go together with a mix-and-match method gained’t make a lot distinction by way of uncomfortable side effects, Pleasure mentioned.
- Breakthrough infections in absolutely vaccinated folks can happen, nevertheless it’s uncommon for them to lead to extreme sickness, hospitalization or demise. You’ll be able to verify if in case you have an lively an infection through the use of an over-the-counter fast check.
Science
Cluster of farmworkers diagnosed with rare animal-borne disease in Ventura County
A cluster of workers at Ventura County berry farms have been diagnosed with a rare disease often transmitted through sick animals’ urine, according to a public health advisory distributed to local doctors by county health officials Tuesday.
The bacterial infection, leptospirosis, has resulted in severe symptoms for some workers, including meningitis, an inflammation of the brain lining and spinal cord. Symptoms for mild cases included headaches and fevers.
The disease, which can be fatal, rarely spreads from human to human, according to the U.S. Centers for Disease Control and Prevention.
Ventura County Public Health has not given an official case count but said it had not identified any cases outside of the agriculture sector. The county’s agriculture commissioner was aware of 18 cases, the Ventura County Star reported.
The health department said it was first contacted by a local physician in October, who reported an unusual trend in symptoms among hospital patients.
After launching an investigation, the department identified leptospirosis as a probable cause of the illness and found most patients worked on caneberry farms that utilize hoop houses — greenhouse structures to shelter the crops.
As the investigation to identify any additional cases and the exact sources of exposure continues, Ventura County Public Health has asked healthcare providers to consider a leptospirosis diagnosis for sick agricultural workers, particularly berry harvesters.
Rodents are a common source and transmitter of disease, though other mammals — including livestock, cats and dogs — can transmit it as well.
The disease is spread through bodily fluids, such as urine, and is often contracted through cuts and abrasions that contact contaminated water and soil, where the bacteria can survive for months.
Humans can also contract the illness through contaminated food; however, the county health agency has found no known health risks to the general public, including through the contact or consumption of caneberries such as raspberries and blackberries.
Symptom onset typically occurs between two and 30 days after exposure, and symptoms can last for months if untreated, according to the CDC.
The illness often begins with mild symptoms, with fevers, chills, vomiting and headaches. Some cases can then enter a second, more severe phase that can result in kidney or liver failure.
Ventura County Public Health recommends agriculture and berry harvesters regularly rinse any cuts with soap and water and cover them with bandages. They also recommend wearing waterproof clothing and protection while working outdoors, including gloves and long-sleeve shirts and pants.
While there is no evidence of spread to the larger community, according to the department, residents should wash hands frequently and work to control rodents around their property if possible.
Pet owners can consult a veterinarian about leptospirosis vaccinations and should keep pets away from ponds, lakes and other natural bodies of water.
Science
Political stress: Can you stay engaged without sacrificing your mental health?
It’s been two weeks since Donald Trump won the presidential election, but Stacey Lamirand’s brain hasn’t stopped churning.
“I still think about the election all the time,” said the 60-year-old Bay Area resident, who wanted a Kamala Harris victory so badly that she flew to Pennsylvania and knocked on voters’ doors in the final days of the campaign. “I honestly don’t know what to do about that.”
Neither do the psychologists and political scientists who have been tracking the country’s slide toward toxic levels of partisanship.
Fully 69% of U.S. adults found the presidential election a significant source of stress in their lives, the American Psychological Assn. said in its latest Stress in America report.
The distress was present across the political spectrum, with 80% of Republicans, 79% of Democrats and 73% of independents surveyed saying they were stressed about the country’s future.
That’s unhealthy for the body politic — and for voters themselves. Stress can cause muscle tension, headaches, sleep problems and loss of appetite. Chronic stress can inflict more serious damage to the immune system and make people more vulnerable to heart attacks, strokes, diabetes, infertility, clinical anxiety, depression and other ailments.
In most circumstances, the sound medical advice is to disengage from the source of stress, therapists said. But when stress is coming from politics, that prescription pits the health of the individual against the health of the nation.
“I’m worried about people totally withdrawing from politics because it’s unpleasant,” said Aaron Weinschenk, a political scientist at the University of Wisconsin–Green Bay who studies political behavior and elections. “We don’t want them to do that. But we also don’t want them to feel sick.”
Modern life is full of stressors of all kinds: paying bills, pleasing difficult bosses, getting along with frenemies, caring for children or aging parents (or both).
The stress that stems from politics isn’t fundamentally different from other kinds of stress. What’s unique about it is the way it encompasses and enhances other sources of stress, said Brett Ford, a social psychologist at the University of Toronto who studies the link between emotions and political engagement.
For instance, she said, elections have the potential to make everyday stressors like money and health concerns more difficult to manage as candidates debate policies that could raise the price of gas or cut off access to certain kinds of medical care.
Layered on top of that is the fact that political disagreements have morphed into moral conflicts that are perceived as pitting good against evil.
“When someone comes into power who is not on the same page as you morally, that can hit very deeply,” Ford said.
Partisanship and polarization have raised the stakes as well. Voters who feel a strong connection to a political party become more invested in its success. That can make a loss at the ballot box feel like a personal defeat, she said.
There’s also the fact that we have limited control over the outcome of an election. A patient with heart disease can improve their prognosis by taking medicine, changing their diet, getting more exercise or quitting smoking. But a person with political stress is largely at the mercy of others.
“Politics is many forms of stress all rolled into one,” Ford said.
Weinschenk observed this firsthand the day after the election.
“I could feel it when I went into my classroom,” said the professor, whose research has found that people with political anxiety aren’t necessarily anxious in general. “I have a student who’s transgender and a couple of students who are gay. Their emotional state was so closed down.”
That’s almost to be expected in a place like Wisconsin, whose swing-state status caused residents to be bombarded with political messages. The more campaign ads a person is exposed to, the greater the risk of being diagnosed with anxiety, depression or another psychological ailment, according to a 2022 study in the journal PLOS One.
Political messages seem designed to keep voters “emotionally on edge,” said Vaile Wright, a licensed psychologist in Villa Park, Ill., and a member of the APA’s Stress in America team.
“It encourages emotion to drive our decision-making behavior, as opposed to logic,” Wright said. “When we’re really emotionally stimulated, it makes it so much more challenging to have civil conversation. For politicians, I think that’s powerful, because emotions can be very easily manipulated.”
Making voters feel anxious is a tried-and-true way to grab their attention, said Christopher Ojeda, a political scientist at UC Merced who studies mental health and politics.
“Feelings of anxiety can be mobilizing, definitely,” he said. “That’s why politicians make fear appeals — they want people to get engaged.”
On the other hand, “feelings of depression are demobilizing and take you out of the political system,” said Ojeda, author of “The Sad Citizen: How Politics is Depressing and Why it Matters.”
“What [these feelings] can tell you is, ‘Things aren’t going the way I want them to. Maybe I need to step back,’” he said.
Genessa Krasnow has been seeing a lot of that since the election.
The Seattle entrepreneur, who also campaigned for Harris, said it grates on her to see people laughing in restaurants “as if nothing had happened.” At a recent book club meeting, her fellow group members were willing to let her vent about politics for five minutes, but they weren’t interested in discussing ways they could counteract the incoming president.
“They’re in a state of disengagement,” said Krasnow, who is 56. She, meanwhile, is looking for new ways to reach young voters.
“I am exhausted. I am so sad,” she said. “But I don’t believe that disengaging is the answer.”
That’s the fundamental trade-off, Ojeda said, and there’s no one-size-fits-all solution.
“Everyone has to make a decision about how much engagement they can tolerate without undermining their psychological well-being,” he said.
Lamirand took steps to protect her mental health by cutting social media ties with people whose values aren’t aligned with hers. But she will remain politically active and expects to volunteer for phone-banking duty soon.
“Doing something is the only thing that allows me to feel better,” Lamirand said. “It allows me to feel some level of control.”
Ideally, Ford said, people would not have to choose between being politically active and preserving their mental health. She is investigating ways to help people feel hopeful, inspired and compassionate about political challenges, since these emotions can motivate action without triggering stress and anxiety.
“We want to counteract this pattern where the more involved you are, the worse you are,” Ford said.
The benefits would be felt across the political spectrum. In the APA survey, similar shares of Democrats, Republicans and independents agreed with statements like, “It causes me stress that politicians aren’t talking about the things that are most important to me,” and, “The political climate has caused strain between my family members and me.”
“Both sides are very invested in this country, and that is a good thing,” Wright said. “Antipathy and hopelessness really doesn’t serve us in the long run.”
Science
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