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Valley fever is a growing risk in Central California; few visitors ever get a warning

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Valley fever is a growing risk in Central California; few visitors ever get a warning

When Nora Bruhn bought admission to the Lightning in a Bottle arts and music festival on the shores of Kern County’s Buena Vista Lake earlier this spring, her ticket never mentioned she might end up with a fungus growing in her lungs.

After weeks of night sweats, “heaviness and a heat” in her left lung, a cough that wouldn’t quit and a painful rash on her legs, her physician brother said she might have valley fever, a potentially deadly disease caused by a dust-loving fungus that lives in the soils of the San Joaquin Valley.

Bruhn said she hadn’t been warned beforehand that Kern County and Buena Vista Lake are endemic for coccidioides — the fungus that causes the disease.

“If there had been a warning that there’s a potentially lethal fungal entity in the soil, there’s no way I would have gone,” said the San Francisco-based artist. “Honestly, I would have just been paranoid to breathe the whole entire time I was there.”

The incidence and range of valley fever has grown dramatically over the last two decades, and some experts warn that the fungus is growing increasingly resistant to drugs — a phenomenon they say is due to the spraying of antifungal agents on area crops.

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As annual cases continue to rise, local health officers have sought to increase awareness of the disease and its symptoms, which are often misdiagnosed. This messaging however focuses only on Kern County and other Central Valley locations and rarely reaches those who live outside Kern County, or other high-risk areas.

In the case of the Lightning in a Bottle festival, Bruhn said she wasn’t provided with any information about the risk on her ticket, or in materials provided to her by the event organizers. As far as she can recall, there were no signs or warnings at the site where she ate, slept, danced and inhaled dust for six straight days.

And she wasn’t the only one infected. According to state health officials, 19 others were diagnosed with coccidioidomycosis in the weeks and months following the event. Five were hospitalized.

According to a statement provided by the California Department of Public Health, officials have been in communication with organizers and “encouraged” them to notify “attendees about valley fever and providing attendees with recommendations to follow up with healthcare providers if they develop illness.”

Do LaB, the company that stages the festival, said through a spokesperson that it adheres to the health and safety guidance provided by federal, state and local authorities. “Health and safety is always the primary concern,” they said.

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The company’s website warns festivalgoers about the prevalence of dust — but doesn’t mention the fungus or the disease.

“Some campgrounds and stage areas will be on dusty terrain,” the website says. “We strongly recommend that everyone bring a scarf, bandana, or dust mask in case the wind kicks up! We also recommend goggles and sunglasses.”

Bruhn said that’s not enough.

“I think it’s really irresponsible to have a festival in a place where breathing is possibly a life-threatening act,” she said.

Kern County’s health department is also in discussions with the production company.

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Kern County’s Buena Vista Lake was the site of the Lightning in a Bottle festival this spring.

(Nora Bruhn)

In California, the number of valley fever cases has risen more than 600% since 2000. In 2001, fewer than 1,500 Californians were diagnosed. Last year, that number was more than 9,000.

Most people who are infected will not experience symptoms, and their bodies will fight off the infection naturally. Those who do suffer symptoms however are often hard-pressed to recognize them, as they resemble the onset of COVID or the flu. This further complicates efforts to address the disease.

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Take for example the case of Brynn Carrigan, Kern County’s director of public health.

In April, Carrigan began getting a lot of headaches. Not really a “headache person,” she chalked them up to stress: Managing a high-profile public health job while also parenting two teenagers. But as the days and weeks went by, the headaches became more frequent, longer in duration and increasingly painful. She also developed an agonizing sensitivity to light.

“I’ve never experienced sensitivity to light like that … all the curtains in my house had to be closed. I was wearing sunglasses inside — because even the clock on my microwave and my oven, and the cable box … oh, my God, it caused excruciating pain,” she said. In order to leave the house, she had to put a blanket over her head because the pain caused by sunlight was unbearable.

She also developed nausea and began vomiting, which led to significant weight loss. Soon she became so exhausted she couldn’t shower without needing to lie down and sleep afterward.

Her doctors ordered blood work and a CT scan. They told her to get a massage, suggesting her symptoms were the result of tension. Another surmised her symptoms were the result of dehydration.

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Eventually, it got so bad she was hospitalized.

When test results came in, her doctors told Carrigan she had a case of disseminated valley fever, a rare but very serious form of the disease that affects the brain and spine rather than the lungs. In retrospect, she said she probably had the disease for months.

A tractor plows a field as a trail of dust rises behind it.

Valley fever, a fungal infection, spreads through dust.

(Jason Armond/Los Angeles Times)

And yet, here she was, arguably the most high-profile public health official in a county recognized as a hot spot for the fungus and the disease, misdiagnosed by herself and other health professionals repeatedly before someone finally decided to test her for the fungus.

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Now she’ll have to take expensive antifungal medications for the rest of her life — medication that has resulted in her losing her hair, including her eyelashes, as well as making her skin and mouth constantly dry.

As a result of Carrigan’s experience, her agency is running public service announcements on TV, radio and in movie theaters. She does news conferences, talks to reporters and runs presentations for outdoor workforces — solar farms, agriculture and construction — to educate those “individuals that have no choice but to be outside and really disturbing the soil.” She’s also hoping to get in schools.

But she realizes her influence is geographically constrained. She can really only speak to the people who live there.

For people who come to Kern County for a visit — like Bruhn and the 20,000 other concertgoers who attended Lightning in a Bottle this year — once they leave, they’re on their own.

Dust rises behind a truck on a dirt road.

A truck raises dust on a dirt road in Bakersfield in March 2022.

(Jason Armond/Los Angeles Times)

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Outside of California, valley fever is also prevalent in Arizona and some areas of Nevada, New Mexico, Utah and Texas, as well as parts of Mexico and Central and South America

Experts worry that as the range of valley fever spreads — whether by a changing climate, shifting demographics, or increased construction in areas once left to coyotes, desert rodents and cacti — more and more severe cases will appear.

They’re also concerned that the fungus is building resistance to the medicines used to fight it.

Antje Lauer, a professor of microbiology at Cal State Bakersfield and a “cocci” fungus expert, said she and her students have found growing pharmaceutical resistance in the fungus, the result of the use of agricultural fungicides on crops.

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She said the drug fluconazole — the fungicide doctors prescribe off-label to treat the disease — is nearly identical in molecular structure to the antifungal agents “being sprayed against plant pathogens. … So when a pathogen gets exposed via those pesticides, the valley fever fungus is also in those soils. It gets exposed and is building an immunity.”

It’s the kind of thing that really concerns G.R. Thompson, a professor of medicine at UC Davis and an expert in the treatment of valley fever and other fungal diseases.

“If you ask me, what keeps you up at night about valley fever or fungal infections?, it’s what we do to the environment” he said. “We learned that giving chickens and livestock antibiotics was bad, because even though they grew faster, it led to antibiotic resistance. Right now, we’re kind of having our own reckoning with fungal infections in the environment. We’re putting down antifungals on our crops, and now our fungi are become resistant before our patients have ever even been treated.”

He said he and other health and environment professionals are working with various local, state and federal agencies “to make sure that everybody’s talking to each other. You know that what we’re putting down on our crops is not going to cause problems in our hospitals.”

Because at the same time, he said, there’s a growing concern that the fungus has become more severe in terms of clinical outcomes.

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“We’re seeing more patients in the hospital this year than ever before, which has us wondering … has the fungus changed?” he said, quickly adding that health experts are actively investigating this question and don’t have an answer.

John Galgiani, who runs the Valley Fever Center for Excellence out of the University of Arizona in Tucson, is hopeful that a vaccine may be forthcoming.

He said a Long Beach-based medical startup called Anivive got a contract to take a vaccine that’s being developed for dogs — outdoor-loving creatures with noses to the ground and a penchant for digging, and therefore susceptible to the disease — and reformulate it to make it suitable for human clinical trials.

He said prison populations, construction workers, farmworkers, firefighters, archaeologists — anyone who digs in the soil, breaths it in or spends time outdoors in these areas — would be suitable populations for such inoculations.

But he, like everyone else The Times spoke with, believes education and outreach are the most important tools in the fight against the disease.

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As there is with any other risky activity, he said, if people are aware, such knowledge empowers them with choice — and in this case, the tools they need to help themselves should they fall ill.

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Political stress: Can you stay engaged without sacrificing your mental health?

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Political stress: Can you stay engaged without sacrificing your mental health?

It’s been two weeks since Donald Trump won the presidential election, but Stacey Lamirand’s brain hasn’t stopped churning.

“I still think about the election all the time,” said the 60-year-old Bay Area resident, who wanted a Kamala Harris victory so badly that she flew to Pennsylvania and knocked on voters’ doors in the final days of the campaign. “I honestly don’t know what to do about that.”

Neither do the psychologists and political scientists who have been tracking the country’s slide toward toxic levels of partisanship.

Fully 69% of U.S. adults found the presidential election a significant source of stress in their lives, the American Psychological Assn. said in its latest Stress in America report.

The distress was present across the political spectrum, with 80% of Republicans, 79% of Democrats and 73% of independents surveyed saying they were stressed about the country’s future.

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That’s unhealthy for the body politic — and for voters themselves. Stress can cause muscle tension, headaches, sleep problems and loss of appetite. Chronic stress can inflict more serious damage to the immune system and make people more vulnerable to heart attacks, strokes, diabetes, infertility, clinical anxiety, depression and other ailments.

In most circumstances, the sound medical advice is to disengage from the source of stress, therapists said. But when stress is coming from politics, that prescription pits the health of the individual against the health of the nation.

“I’m worried about people totally withdrawing from politics because it’s unpleasant,” said Aaron Weinschenk, a political scientist at the University of Wisconsin–Green Bay who studies political behavior and elections. “We don’t want them to do that. But we also don’t want them to feel sick.”

Modern life is full of stressors of all kinds: paying bills, pleasing difficult bosses, getting along with frenemies, caring for children or aging parents (or both).

The stress that stems from politics isn’t fundamentally different from other kinds of stress. What’s unique about it is the way it encompasses and enhances other sources of stress, said Brett Ford, a social psychologist at the University of Toronto who studies the link between emotions and political engagement.

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For instance, she said, elections have the potential to make everyday stressors like money and health concerns more difficult to manage as candidates debate policies that could raise the price of gas or cut off access to certain kinds of medical care.

Layered on top of that is the fact that political disagreements have morphed into moral conflicts that are perceived as pitting good against evil.

“When someone comes into power who is not on the same page as you morally, that can hit very deeply,” Ford said.

Partisanship and polarization have raised the stakes as well. Voters who feel a strong connection to a political party become more invested in its success. That can make a loss at the ballot box feel like a personal defeat, she said.

There’s also the fact that we have limited control over the outcome of an election. A patient with heart disease can improve their prognosis by taking medicine, changing their diet, getting more exercise or quitting smoking. But a person with political stress is largely at the mercy of others.

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“Politics is many forms of stress all rolled into one,” Ford said.

Weinschenk observed this firsthand the day after the election.

“I could feel it when I went into my classroom,” said the professor, whose research has found that people with political anxiety aren’t necessarily anxious in general. “I have a student who’s transgender and a couple of students who are gay. Their emotional state was so closed down.”

That’s almost to be expected in a place like Wisconsin, whose swing-state status caused residents to be bombarded with political messages. The more campaign ads a person is exposed to, the greater the risk of being diagnosed with anxiety, depression or another psychological ailment, according to a 2022 study in the journal PLOS One.

Political messages seem designed to keep voters “emotionally on edge,” said Vaile Wright, a licensed psychologist in Villa Park, Ill., and a member of the APA’s Stress in America team.

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“It encourages emotion to drive our decision-making behavior, as opposed to logic,” Wright said. “When we’re really emotionally stimulated, it makes it so much more challenging to have civil conversation. For politicians, I think that’s powerful, because emotions can be very easily manipulated.”

Making voters feel anxious is a tried-and-true way to grab their attention, said Christopher Ojeda, a political scientist at UC Merced who studies mental health and politics.

“Feelings of anxiety can be mobilizing, definitely,” he said. “That’s why politicians make fear appeals — they want people to get engaged.”

On the other hand, “feelings of depression are demobilizing and take you out of the political system,” said Ojeda, author of “The Sad Citizen: How Politics is Depressing and Why it Matters.”

“What [these feelings] can tell you is, ‘Things aren’t going the way I want them to. Maybe I need to step back,’” he said.

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Genessa Krasnow has been seeing a lot of that since the election.

The Seattle entrepreneur, who also campaigned for Harris, said it grates on her to see people laughing in restaurants “as if nothing had happened.” At a recent book club meeting, her fellow group members were willing to let her vent about politics for five minutes, but they weren’t interested in discussing ways they could counteract the incoming president.

“They’re in a state of disengagement,” said Krasnow, who is 56. She, meanwhile, is looking for new ways to reach young voters.

“I am exhausted. I am so sad,” she said. “But I don’t believe that disengaging is the answer.”

That’s the fundamental trade-off, Ojeda said, and there’s no one-size-fits-all solution.

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“Everyone has to make a decision about how much engagement they can tolerate without undermining their psychological well-being,” he said.

Lamirand took steps to protect her mental health by cutting social media ties with people whose values aren’t aligned with hers. But she will remain politically active and expects to volunteer for phone-banking duty soon.

“Doing something is the only thing that allows me to feel better,” Lamirand said. “It allows me to feel some level of control.”

Ideally, Ford said, people would not have to choose between being politically active and preserving their mental health. She is investigating ways to help people feel hopeful, inspired and compassionate about political challenges, since these emotions can motivate action without triggering stress and anxiety.

“We want to counteract this pattern where the more involved you are, the worse you are,” Ford said.

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The benefits would be felt across the political spectrum. In the APA survey, similar shares of Democrats, Republicans and independents agreed with statements like, “It causes me stress that politicians aren’t talking about the things that are most important to me,” and, “The political climate has caused strain between my family members and me.”

“Both sides are very invested in this country, and that is a good thing,” Wright said. “Antipathy and hopelessness really doesn’t serve us in the long run.”

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Video: SpaceX Unable to Recover Booster Stage During Sixth Test Flight

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Video: SpaceX Unable to Recover Booster Stage During Sixth Test Flight

President-elect Donald Trump joined Elon Musk in Texas and watched the launch from a nearby location on Tuesday. While the Starship’s giant booster stage was unable to repeat a “chopsticks” landing, the vehicle’s upper stage successfully splashed down in the Indian Ocean.

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Alameda County child believed to be latest case of bird flu; source unknown

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Alameda County child believed to be latest case of bird flu; source unknown

California health officials reported Tuesday that a child in Alameda County tested positive for H5 bird flu last week.

The source of infection is not known — although health officials are looking into possible contact with wild birds — and the child is recovering at home with mild upper respiratory symptoms.

Health officials have confirmed the “H5” part of the virus, not the “N1.” There is no human “H5” flu; it is only associated with birds.

The child was treated with antiviral medication, and the sample was sent to the U.S. Centers for Disease Control and Prevention for confirmatory testing.

The initial test showed low levels of the virus and, according to the state health agency, testing four days later showed no virus.

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“The more cases we find that have no known exposure make it difficult to prevent additional” infections, said Jennifer Nuzzo, professor of epidemiology and director of the Brown University School of Public Health’s Pandemic Center. “It worries me greatly that this virus is popping up in more and more places and that we keep being surprised by infections in people whom we wouldn’t think would be at high risk of being exposed to the virus.”

A statement from the California Department of Public Health said that none of the child’s family members have the virus, although they, too, had mild respiratory symptoms. They are also being treated with antiviral medication.

The child attended a day care while displaying symptoms. People the child may have had contact with have been notified and are being offered preventative antiviral medication and testing.

“It’s natural for people to be concerned, and we want to reinforce for parents, caregivers and families that based on the information and data we have, we don’t think the child was infectious — and no human-to-human spread of bird flu has been documented in any country for more than 15 years,” said CDPH Director and State Public Health Officer Dr. Tomás Aragón.

The case comes days after the state health agency announced the discovery of six new bird flu cases, all in dairy workers. The total number of confirmed human cases in California is 27. This new case will bring it to 28, if confirmed. This is the first human case in California that is not associated with the dairy industry.

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The total number of confirmed human cases in the U.S., including the Alameda County child, now stands at 54. Thirty-one are associated with dairy industry, 21 with the poultry industry, and now two with unknown sources.

In Canada, a teenager is in critical condition with the disease. The source of that child’s infection is also unknown.

Genetic sequencing of the Canadian teenager’s virus shows mutations that may make it more efficient at moving between people. The Canadian virus is also a variant of H5N1 that has been associated with migrating wild birds, not cattle.

Genetic sequencing of the California child’s virus has not been released, so it is unclear if it is of wild bird origin, or the one moving through the state’s dairy herds.

In addition, WastewaterScan — an infectious disease monitoring network led by researchers from Stanford University and Emory University, with laboratory support from Verily, Alphabet Inc.’s life sciences organization — follows 28 wastewater sites in California. All but six have shown detectable amounts of H5 in the last couple of weeks.

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There are no monitoring sites in Alameda Co., but positive hits have been found in several Bay Area wastewater districts, including San Francisco, Redwood City, Sunnyvale, San Jose and Napa.

“This just makes the work of protecting people from this virus and preventing it from mutating to cause a pandemic that much harder,” said Nuzzo.

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