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Trump Administration Slashes Research Into L.G.B.T.Q. Health

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Trump Administration Slashes Research Into L.G.B.T.Q. Health

The Trump administration has scrapped more than $800 million worth of research into the health of L.G.B.T.Q. people, abandoning studies of cancers and viruses that tend to affect members of sexual minority groups and setting back efforts to defeat a resurgence of sexually transmitted infections, according to an analysis of federal data by The New York Times.

In keeping with its deep opposition to both diversity programs and gender-affirming care for adolescents, the administration has worked aggressively to root out research touching on equity measures and transgender health.

But its crackdown has reverberated far beyond those issues, eliminating swaths of medical research on diseases that disproportionately afflict L.G.B.T.Q. people, a group that comprises nearly 10 percent of American adults.

Of the 669 grants that the National Institutes of Health had canceled in whole or in part as of early May, at least 323 — nearly half of them — related to L.G.B.T.Q. health, according to a review by The Times of every terminated grant.

Federal officials had earmarked $806 million for the canceled projects, many of which had been expected to draw more funding in the years to come.

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Scores of research institutions lost funding, a list that includes not only White House targets like Johns Hopkins and Columbia, but also public universities in the South and the Midwest, like Ohio State University and the University of Alabama at Birmingham.

At Florida State University, $41 million worth of research was canceled, including a major effort to prevent H.I.V. in adolescents and young adults, who experience a fifth of new infections in the United States each year.

In termination letters over the last two months, the N.I.H. justified the cuts by telling scientists that their L.G.B.T.Q. work “no longer effectuates agency priorities.” In some cases, the agency said canceled research had been “based on gender identity,” which gave rise to “unscientific” results that ignored “biological realities.”

Other termination letters told scientists their studies erred by being “based primarily on artificial and nonscientific categories, including amorphous equity objectives.”

The cuts follow a surge in federal funding for L.G.B.T.Q. research over the past decade, and active encouragement from the N.I.H. for grant proposals focused on sexual and gender minority groups that began during the Obama administration.

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President Trump’s allies have argued that the research is shot through with ideological bias.

“There’s been a train of abuses of the science to fit a preconceived conclusion,” said Roger Severino of the Heritage Foundation, the conservative think tank that helped formulate some Trump administration policies.

“And that was based on an unscientific premise that biology is effectively irrelevant, and a political project of trying to mainstream the notion that people could change their sex.”

Scientists said canceling research on such a broad range of illnesses related to sexual and gender minority groups effectively created a hierarchy of patients, some more worthy than others.

“Certain people in the United States shouldn’t be getting treated as second-class research subjects,” said Simon Rosser, a professor at the University of Minnesota whose lab was studying cancer in L.G.B.T.Q. people before significant funding was pulled.

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“That, I think, is anyone’s definition of bigotry,” he added. “Bigotry in science.”

The canceled projects are among the most vivid manifestations of a broad dismantling of the infrastructure that has for 80 years supported medical research across the United States.

Beyond terminating studies, federal officials have gummed up the grant-making process by slow-walking payments, delaying grant review meetings and scaling back new grant awards.

Bigger changes may be in store: Mr. Trump on Friday proposed reducing the N.I.H. budget from roughly $48 billion to $27 billion, citing in part what he described as the agency’s efforts to promote “radical gender ideology.”

The legality of the mass terminations is unclear. Two separate lawsuits challenging the revocation of a wide range of grants — one filed by a group of researchers, and the other by 16 states — argued that the Trump administration had failed to offer a legal rationale for the cuts.

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The White House and the Department of Health and Human Services did not respond to requests for comment.

Andrew Nixon, a spokesman for the health department, told The Daily Signal, a conservative publication, last month that the move “away from politicized D.E.I. and gender ideology studies” was in “accordance with the president’s executive orders.”

The N.I.H. said in a statement: “N.I.H. is taking action to terminate research funding that is not aligned with N.I.H. and H.H.S. priorities. We remain dedicated to restoring our agency to its tradition of upholding gold-standard, evidence-based science.”

The L.G.B.T.Q. cuts ended studies on antibiotic resistance, undiagnosed autism in sexual minority groups, and certain throat and other cancers that disproportionately affect those groups. Funding losses have led to firings at some L.G.B.T.Q.-focused labs that had only recently been preparing to expand.

The N.I.H. used to reserve grant cancellations for rare cases of research misconduct or possible harm to participants. The latest cuts, far from protecting research participants, are instead putting them in harm’s way, scientists said.

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They cited the jettisoning of clinical trials, which have now been left without federal funding to care for volunteer participants.

“We’re stopping things that are preventing suicide and preventing sexual violence,” said Katie Edwards, a professor at the University of Michigan, whose funding for several clinical trials involving L.G.B.T.Q. people was canceled.

H.I.V. research has been hit particularly hard.

The N.I.H. ended several major grants to the Adolescent Medicine Trials Network for H.I.V./AIDS Intervention, a program that had helped lay the groundwork for the use in adolescents of a medication regimen that can prevent infections.

That regimen, known as pre-exposure prophylaxis, or PrEP, is credited with helping beat back the disease in young people.

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Cuts to the program have endangered an ongoing trial of a product that would prevent both H.I.V. and pregnancy and a second trial looking at combining sexual health counseling with behavioral therapy to reduce the spread of H.I.V. in young sexual minority men who use stimulants.

Together with the termination of dozens of other H.I.V. studies, the cuts have undermined Mr. Trump’s stated goal from his first term to end the country’s H.I.V. epidemic within a decade, scientists said.

The N.I.H. terminated work on other sexually transmitted illnesses, as well.

Dr. Matthew Spinelli, an infectious disease researcher at the University of California, San Francisco, was in the middle of a clinical trial of doxycycline, a common antibiotic that, taken after sex, can prevent some infections with syphilis, gonorrhea and chlamydia.

The trial was, he said, “as nerdy as it gets”: a randomized study in which participants were given different regimens of the antibiotic to see how it is metabolized.

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He hoped the findings would help scientists understand the drug’s effectiveness in women, and also its potential to cause drug resistance, a concern that Secretary of State Marco Rubio had voiced in the past.

But health officials, citing their opposition to research regarding “gender identity,” halted funding for the experiment in March. That left Dr. Spinelli without any federal funding to monitor the half-dozen people who had already been taking the antibiotic.

It also put the thousands of doses that Dr. Spinelli had bought with taxpayer money at risk of going to waste. He said stopping work on diseases like syphilis and H.I.V. would allow new outbreaks to spread.

“The H.I.V. epidemic is going to explode again as a result of these actions,” said Dr. Spinelli, who added that he was speaking only for himself, not his university. “It’s devastating for the communities affected.”

Despite a recent emphasis on the downsides of transitioning, federal officials canceled several grants examining the potential risks of gender-affirming hormone therapy. The projects looked at whether hormone therapy could, for example, increase the risk of breast cancer, cardiovascular disease, altered brain development or H.I.V.

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Other terminated grants examined ways of addressing mental illness in transgender people, who now make up about 3 percent of high school students and report sharply higher rates of persistent sadness and suicide attempts.

For Dr. Edwards, of the University of Michigan, funding was halted for a clinical trial looking at how online mentoring might reduce depression and self-harm among transgender teens, one of six studies of hers that were canceled.

Another examined interventions for the families of L.G.B.T.Q. young people to promote more supportive caregiving and, in turn, reduce dating violence and alcohol use among the young people.

The N.I.H. categorizes research only by certain diseases, making it difficult to know how much money the agency devotes to L.G.B.T.Q. health. But a report in March estimated that such research made up less than 1 percent of the N.I.H. portfolio over a decade.

The Times sought to understand the scale of terminated funding for L.G.B.T.Q. medical research by reviewing the titles and, in many cases, research summaries for each of the 669 grants that the Trump administration said it had canceled in whole or in part as of early May.

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Beyond grants related to L.G.B.T.Q. people and the diseases and treatments that take a disproportionate toll on them, The Times included in its count studies that were designed to recruit participants from sexual and gender minority groups.

It excluded grants related to illnesses like H.I.V. that were focused on non-L.G.B.T.Q. patients.

While The Times examined only N.I.H. research grants, the Trump administration is also ending or considering ending L.G.B.T.Q. programs elsewhere in the federal health system. It has proposed, for example, scrapping a specialized suicide hotline for L.G.B.T.Q. young people.

The research cuts stand to hollow out a field that in the last decade had not only grown larger, but also come to encompass a wider range of disease threats beyond H.I.V.

Already, scientists said, younger researchers are losing jobs in sexual and gender minority research and scrubbing their online biographies of evidence that they ever worked in the field.

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Five grants obtained by Brittany Charlton, a professor at the Harvard School of Public Health, have been canceled, including one looking at sharply elevated rates of stillbirths among L.G.B.T.Q. women.

Ending research on disease threats to gender and sexual minority groups, she said, would inevitably rebound on the entire population. “When other people are sick around you, it does impact you, even if you may think it doesn’t,” she said.

Irena Hwang contributed reporting.

Science

Trump administration promised ‘gold standard science.’ Scientists say they got fool’s gold

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Trump administration promised ‘gold standard science.’ Scientists say they got fool’s gold

When President Trump announced Robert F. Kennedy Jr. as his pick for Health and Human Services secretary, he declared that the appointment marked the return of “Gold Standard Scientific Research” in the U.S.

In May 2025 Trump signed the “Restoring Gold Standard Science” executive order. Agencies including NASA and the Department of Energy filed reports on how their science met the official White House “gold standard.” Administration figures peppered public remarks, publications and social media posts with the phrase.

On paper, the administration’s nine-point definition for “gold standard science” reads like a list of fundamental research integrity principles that any scientist would endorse: science that is reproducible, transparent, forthcoming on error and uncertainty, collaborative, skeptical, built on falsifiable hypotheses, impartially peer reviewed, accepting of negative results and free of conflicts of interest.

In practice, critics say, the phrase has become shorthand for science in which preferred outcomes outweigh inconvenient evidence.

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“This use of ‘gold standard science’ is deceptive. It sounds really good on its face. It’s advocating for things that are normative in the scientific community,” said Jules Barbati-Dajches, an analyst at the Union of Concerned Scientists, a nonprofit advocacy group.

The same executive order that turned the term into a policy rolled back all scientific integrity policies established during the Biden administration, Barbati-Dajches pointed out, making it harder to pursue and publish scientific findings without threat of political interference.

“It undercuts all of the values and standards and principles that were already being prioritized and implemented in federal agencies,” Barbati-Dajches said.

The executive order describes a decline in public trust in science that began during the COVID-19 pandemic. It cites examples in which government agencies “used or promoted scientific information in a highly misleading manner,” such as the Centers for Disease Control and Prevention’s school-reopening guidelines, a contentious count of the North Atlantic right whale population by the National Marine Fisheries Service and the use by several government agencies of an Intergovernmental Panel on Climate Change warming model that the executive order describes as “highly unlikely.”

“The Trump administration is ensuring that political agendas and ideologies never again corrupt policymaking that should be guided only by Gold Standard Science,” White House spokesman Kush Desai wrote in response to questions from The Times. “So-called ‘scientists’ who are only now concerned that politics are being prioritized over evidence after having stayed silent during the pandemic era are either delusional or partisan hacks.”

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Credible, reliable and impartial evidence is the goal of legitimate science. But “the use of the term ‘gold standard science’ is being preferentially used based on the context,” said Dr. Daniel Jernigan, who resigned as director of the CDC’s National Center for Emerging and Zoonotic Infectious Diseases in August over concerns that its new leadership was not taking an “evidence-based approach to things,” he said at the time.

Jernigan cited Kennedy’s changes to the Advisory Committee on Immunization Practices, which advises the CDC on vaccinations. The committee had long followed a set of guidelines known as the Evidence to Recommendations framework, which establishes clear rules for how different types of evidence must be weighed and evaluated when making decisions.

Kennedy replaced the entire 17-member committee with a handpicked group heavily weighted toward vaccine skepticism. “Public trust has eroded,” Kennedy said at the time. “Only through radical transparency and gold standard science, will we earn it back.”

The reconstituted group largely abandoned the framework, allowing the committee to judge evidence of dubious quality alongside large randomized controlled trials.

Its first meeting included an error-filled presentation from a vaccine skeptic on the preservative thimerosal that focused only on a few reports of the shot harming individuals, but left out the many studies that have shown its safety across large populations. The committee ultimately voted not to recommend further vaccines containing thimerosal, which was already removed from childhood vaccines in 2001.

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Meanwhile, Jernigan noted, National Institutes of Health director and acting CDC director Dr. Jay Bhattacharya has continued to delay the release of a study that found COVID-19 vaccines reduced hospitalizations related to the virus by 55%.

According to media reports, the study used hospital patients’ vaccination status to calculate the success of the season’s vaccine, a method long used to determine flu vaccine effectiveness. Bhattacharya reportedly wanted to wait for a randomized clinical trial — a method that scientists frequently cite as the “gold standard” for determining an intervention’s effectiveness, but one that is expensive and too time-consuming to evaluate the success of a seasonal flu or COVID-19 shot.

Accepting a lower standard of evidence for vaccines’ reported harms than for their apparent benefits “is not a good way to practice science: that your ideology, your decision about how things should be, determines what your evidence is,” Jernigan said.

The Trump administration didn’t coin the term “gold standard science,” which has been floating around for at least half a century as a label for top-quality research methods. Over the decades, critics have pointed out that it’s not as shiny a metaphor as it seems.

In finance, the gold standard fixes a currency’s value against a specific quantity of a specific object. But in science, nothing is fixed. Old conclusions and beliefs are constantly being overwritten as new evidence comes to light.

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“Gold standard science in 1990 would be malpractice in some respects in 2026, and five years from now the gold standard may have changed again, because we’re constantly innovating,” said David Blumenthal, a professor at the Harvard School of Public Health and co-author of the book “Whiplash: From the Battle for Obamacare to the War on Science.”

“Science is changeable and the methods improve constantly, and the people who are most familiar with the possibilities and realities of those methods are the people doing the work at any given time,” he said. “And if they’re not involved, then it’s not gold standard.”

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The longer a species stays in the wildlife trade, the more dangerous it becomes. A new study explains why

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The longer a species stays in the wildlife trade, the more dangerous it becomes. A new study explains why

Animals traded through global wildlife markets are far more likely to carry diseases that can infect humans, and the risk grows the longer those species remain in circulation, according to a new study.

The analysis, published Thursday in Science, examined decades of global wildlife trade data and found that 41% of traded mammal species share at least one pathogen with humans, compared with just 6.4% of species not involved in trade.

The researchers also found that the number of pathogens shared between animals and humans increases over time. On average, a species acquires one additional human-infecting pathogen for every decade it is present in the global wildlife trade.

The findings suggest that wildlife trade does not simply expose humans to existing disease risks, but may actively amplify them over time.

“Our study is the strongest evidence to date that reducing wildlife trade will reduce pandemic risk,” said Colin Carlson, an epidemiologist at the Yale School of Public Health and a co-author of the study.

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Scientists have already long linked wildlife trade to specific outbreaks such as HIV, Ebola and COVID-19. The new research, which draws on 40 years of global trade records and pathogen data, attempts to measure the relationship on a larger scale.

The results point to a broader pattern. Repeated and prolonged contact between humans and wild animals creates more opportunities for pathogens to move between species.

“What stands out most is how clearly the findings reinforce something many of us in disease ecology have been concerned about for years: it’s not just the presence of wildlife trade, but the intensity and duration of contact that elevates risk,” said Thomas Gillespie, a professor of environmental sciences and environmental health at Emory University, who was not involved in the study.

Wildlife trade, as defined in this study, includes a wide range of activities, from hunting and breeding to transport, storage and sale. At each stage, animals are handled, confined and often brought into close proximity with both humans and other animal species. These conditions can facilitate the spread of viruses, bacteria and parasites.

Over time, those repeated interactions create more opportunities for pathogens to circulate, adapt and potentially spill over into human populations.

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Carlson said one of the most striking findings was how strongly time in trade predicted pathogen sharing.

“That time-in-trade effect is the smoking gun,” he said. “We wouldn’t see that unless pathogens were jumping from animals to humans.”

He added that the findings suggest wildlife trade should be considered one of the major drivers of disease emergence, alongside deforestation, agriculture and climate change.

The study also found that certain forms of trade may carry higher risks. Species sold in live-animal markets were more likely to share pathogens with humans than those sold as meat or animal products. Illegally traded species also were more likely to be the cause of disease, though researchers emphasized that risk is not limited to illicit markets.

“Focusing on illegal wildlife trade is not enough,” said Meredith Gore, a conservation criminologist at the University of Maryland and a co-author of the study. “Pathogen transmission is a consequence of general and diverse uses of wildlife by people. This includes illegal and legal trade.”

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Most international frameworks governing wildlife trade, including the Convention on International Trade in Endangered Species of Wild Fauna and Flora, or CITES, were designed primarily to protect species from overexploitation, according to Gore.

“There are clear and currently unmet opportunities for more directly including zoonotic disease risk consideration into current regulations,” Gore said.

In particular, the global nature of the trade complicates efforts to manage risk.

“Animals and pathogens do not care about political borders,” said Jérôme Gippet, a biologist at the University of Fribourg and the University of Lausanne in Switzerland and the study’s lead author. “Without globally coordinated efforts, I do not see how we can limit these risks efficiently.”

The researchers say their findings underscore the need for a more coordinated approach that bridges conservation, public health and trade policy and treats wildlife trade as a central driver of global health risk. The study’s findings also highlight gaps in disease surveillance systems, which often fail to detect pathogens circulating in wildlife before they reach humans.

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“Risk is accumulating in a way that current surveillance isn’t capturing,” said Evan Eskew, a disease ecologist at the University of Idaho and a co-author of the study.

Few countries, he said, systematically track which species are being traded across their borders, and even fewer conduct routine pathogen screening in those animals. As a result, potential threats can go undetected until they spill over into human populations.

Eskew said expanding surveillance, particularly for species already known to carry zoonotic pathogens, could help identify risks earlier and prevent outbreaks from spreading.

“We need to be looking for the next pandemic virus on fur farms, in hunting communities, and even at border checkpoints where wildlife are imported,” Carlson said. “Right now, we’re flying blind, especially in places where we’ve criminalized wildlife trade and driven it underground.”

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After Artemis II, here’s what’s next for NASA’s return to the moon

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After Artemis II, here’s what’s next for NASA’s return to the moon

NASA’s 10-day Artemis II mission to fly around the moon safely splashed down off the San Diego coast Friday, marking the end of humanity’s first flight to the moon in over 50 years.

The new NASA administrator, born over a decade after the last Apollo mission, immediately made it clear he intends the gap between Artemis II and the agency’s next moon mission to be much, much shorter.

“You hear sometimes around here, ‘this is a once in a lifetime’ — no its not,” NASA Administrator Jared Isaacman said aboard a recovery vessel out in the Pacific, moments after the crew splashed down. “This is just the beginning, we are going to get back into doing on this with frequency, sending missions to the moon until we land on it in 2028 and start building our base.”

Here’s how the U.S. space agency hopes to do it.

NASA’s vision for the moon

A week before Artemis II launched, NASA outlined its ambitious new plan for creating a sustained presence on the moon, which can serve as a testing ground for eventual missions to Mars.

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Most notably, the agency scrapped long-standing plans to build a space station orbiting the moon, called Gateway. Instead, it would focus on building a base on the lunar surface.

“I think we’d rather be on the surface where a lot of the learning’s going to take place, where we can … build the skills, test the technology, the capabilities we’re going to need some day if we actually go to Mars and want to bring our astronauts home to talk about it,” Isaacman said in an interview with the publication NASASpaceflight.

“It’s not like you’re just going to be on Gateway looking down,” he added. “You’re going to probably be looking down on another country’s astronauts.”

The space agency’s Artemis program is designed to make the moon base vision a reality.

The next Artemis missions

The next Artemis mission is slated for 2027. Artemis III will stick in near-Earth orbit — closer to where the International Space Station sits as opposed to traveling into deep space like Artemis II.

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Around Earth, the agency plans to test docking procedures between its Orion spacecraft and the lunar landers that will carry astronauts from the moon’s orbit down to its surface. To build these landers, it tapped the private space companies Blue Origin, founded by Jeff Bezos, and SpaceX, founded by Elon Musk.

Then, in early 2028, it intends to launch Artemis IV. The Orion spacecraft will carry astronauts to the moon’s orbit, and a lunar lander will take two of them down to the moon’s south pole, where they will spend a week conducting science.

Artemis V and beyond will aim to accelerate the cadence of lunar landings to one every six months and continue to test technology to make lunar landings easier and cheaper.

Lessons from Artemis II

Artemis II focused on putting the Orion spacecraft through its paces — primarily by testing its life support systems and piloting the spacecraft for the first time. For example, the crew dealt with multiple issues with their space toilet.

NASA also used the mission as an opportunity to study Orion’s troubled heat shield, which unexpectedly chipped in more than 100 spots on the uncrewed Artemis I test mission in 2022. By using a new reentry trajectory, Isaacman said that “no unexpected conditions were observed” in initial assessments.

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However, the Orion spacecraft experienced issues with helium valves on Orion’s propulsion system, which helps the crew navigate in space. Ahead of launch, NASA noticed helium leaking in the system but determined, since Artemis II has a much simpler trajectory than future missions, the leaking wouldn’t significantly affect the mission.

In space, the leaking worsened, ultimately convincing NASA it would have to redesign the system for future missions.

Beyond the technical objectives of Artemis II, NASA officials were particularly pleased with the public response to the mission and the astronauts’ ability to connect with the public.

The lunar flyby is already NASA’s most viewed live broadcast on YouTube with more than 27 million views. Artemis II’s launch and splashdown are also within the top five most viewed broadcasts.

In space, the astronauts spoke eloquently of the surreal sights of the moon and their deep love for our home planet.

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“I would suggest to you that when you look up here, you’re not looking at us,” said Canadian Space Agency astronaut and Artemis II mission specialist astronaut Jeremy Hansen, back in Houston Saturday. “We are a mirror reflecting you. And if you like what you see, then just look a little deeper. This is you.”

The hurdles to Artemis III

NASA is already building its next high-power rocket to launch the Artemis III Orion spacecraft. The agency plans to ship the massive orange core stage for the rocket from New Orleans to Florida this month. The Orion spacecraft’s main two sections are already at NASA’s Kennedy Space Center along the Florida coast.

A redesigned heat shield, aimed at addressing the root cause of the unexpected damage during Artemis I, is already built. However, the agency is not yet sure whether it will be able to fix the faulty Orion propulsion system, built in Germany by the European Space Agency, in Florida or if NASA will have to ship it back across the Atlantic.

And neither SpaceX nor Blue Origin have tested their landers in space yet. A NASA audit last month found that “both SpaceX and Blue Origin have experienced schedule delays and face technical and integration challenges that have the potential to further impact lander costs and delivery schedules.”

Yet, NASA remains steadfast on its 2027 launch timeline. The agency promised to announce the Artemis III crew “soon.”

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