Science
Trump Administration Slashes Research Into L.G.B.T.Q. Health

The Trump administration has scrapped more than $800 million worth of research into the health of L.G.B.T.Q. people, abandoning studies of cancers and viruses that tend to affect members of sexual minority groups and setting back efforts to defeat a resurgence of sexually transmitted infections, according to an analysis of federal data by The New York Times.
In keeping with its deep opposition to both diversity programs and gender-affirming care for adolescents, the administration has worked aggressively to root out research touching on equity measures and transgender health.
But its crackdown has reverberated far beyond those issues, eliminating swaths of medical research on diseases that disproportionately afflict L.G.B.T.Q. people, a group that comprises nearly 10 percent of American adults.
Of the 669 grants that the National Institutes of Health had canceled in whole or in part as of early May, at least 323 — nearly half of them — related to L.G.B.T.Q. health, according to a review by The Times of every terminated grant.
Federal officials had earmarked $806 million for the canceled projects, many of which had been expected to draw more funding in the years to come.
Scores of research institutions lost funding, a list that includes not only White House targets like Johns Hopkins and Columbia, but also public universities in the South and the Midwest, like Ohio State University and the University of Alabama at Birmingham.
At Florida State University, $41 million worth of research was canceled, including a major effort to prevent H.I.V. in adolescents and young adults, who experience a fifth of new infections in the United States each year.
In termination letters over the last two months, the N.I.H. justified the cuts by telling scientists that their L.G.B.T.Q. work “no longer effectuates agency priorities.” In some cases, the agency said canceled research had been “based on gender identity,” which gave rise to “unscientific” results that ignored “biological realities.”
Other termination letters told scientists their studies erred by being “based primarily on artificial and nonscientific categories, including amorphous equity objectives.”
The cuts follow a surge in federal funding for L.G.B.T.Q. research over the past decade, and active encouragement from the N.I.H. for grant proposals focused on sexual and gender minority groups that began during the Obama administration.
President Trump’s allies have argued that the research is shot through with ideological bias.
“There’s been a train of abuses of the science to fit a preconceived conclusion,” said Roger Severino of the Heritage Foundation, the conservative think tank that helped formulate some Trump administration policies.
“And that was based on an unscientific premise that biology is effectively irrelevant, and a political project of trying to mainstream the notion that people could change their sex.”
Scientists said canceling research on such a broad range of illnesses related to sexual and gender minority groups effectively created a hierarchy of patients, some more worthy than others.
“Certain people in the United States shouldn’t be getting treated as second-class research subjects,” said Simon Rosser, a professor at the University of Minnesota whose lab was studying cancer in L.G.B.T.Q. people before significant funding was pulled.
“That, I think, is anyone’s definition of bigotry,” he added. “Bigotry in science.”
The canceled projects are among the most vivid manifestations of a broad dismantling of the infrastructure that has for 80 years supported medical research across the United States.
Beyond terminating studies, federal officials have gummed up the grant-making process by slow-walking payments, delaying grant review meetings and scaling back new grant awards.
Bigger changes may be in store: Mr. Trump on Friday proposed reducing the N.I.H. budget from roughly $48 billion to $27 billion, citing in part what he described as the agency’s efforts to promote “radical gender ideology.”
The legality of the mass terminations is unclear. Two separate lawsuits challenging the revocation of a wide range of grants — one filed by a group of researchers, and the other by 16 states — argued that the Trump administration had failed to offer a legal rationale for the cuts.
The White House and the Department of Health and Human Services did not respond to requests for comment.
Andrew Nixon, a spokesman for the health department, told The Daily Signal, a conservative publication, last month that the move “away from politicized D.E.I. and gender ideology studies” was in “accordance with the president’s executive orders.”
The N.I.H. said in a statement: “N.I.H. is taking action to terminate research funding that is not aligned with N.I.H. and H.H.S. priorities. We remain dedicated to restoring our agency to its tradition of upholding gold-standard, evidence-based science.”
The L.G.B.T.Q. cuts ended studies on antibiotic resistance, undiagnosed autism in sexual minority groups, and certain throat and other cancers that disproportionately affect those groups. Funding losses have led to firings at some L.G.B.T.Q.-focused labs that had only recently been preparing to expand.
The N.I.H. used to reserve grant cancellations for rare cases of research misconduct or possible harm to participants. The latest cuts, far from protecting research participants, are instead putting them in harm’s way, scientists said.
They cited the jettisoning of clinical trials, which have now been left without federal funding to care for volunteer participants.
“We’re stopping things that are preventing suicide and preventing sexual violence,” said Katie Edwards, a professor at the University of Michigan, whose funding for several clinical trials involving L.G.B.T.Q. people was canceled.
H.I.V. research has been hit particularly hard.
The N.I.H. ended several major grants to the Adolescent Medicine Trials Network for H.I.V./AIDS Intervention, a program that had helped lay the groundwork for the use in adolescents of a medication regimen that can prevent infections.
That regimen, known as pre-exposure prophylaxis, or PrEP, is credited with helping beat back the disease in young people.
Cuts to the program have endangered an ongoing trial of a product that would prevent both H.I.V. and pregnancy and a second trial looking at combining sexual health counseling with behavioral therapy to reduce the spread of H.I.V. in young sexual minority men who use stimulants.
Together with the termination of dozens of other H.I.V. studies, the cuts have undermined Mr. Trump’s stated goal from his first term to end the country’s H.I.V. epidemic within a decade, scientists said.
The N.I.H. terminated work on other sexually transmitted illnesses, as well.
Dr. Matthew Spinelli, an infectious disease researcher at the University of California, San Francisco, was in the middle of a clinical trial of doxycycline, a common antibiotic that, taken after sex, can prevent some infections with syphilis, gonorrhea and chlamydia.
The trial was, he said, “as nerdy as it gets”: a randomized study in which participants were given different regimens of the antibiotic to see how it is metabolized.
He hoped the findings would help scientists understand the drug’s effectiveness in women, and also its potential to cause drug resistance, a concern that Secretary of State Marco Rubio had voiced in the past.
But health officials, citing their opposition to research regarding “gender identity,” halted funding for the experiment in March. That left Dr. Spinelli without any federal funding to monitor the half-dozen people who had already been taking the antibiotic.
It also put the thousands of doses that Dr. Spinelli had bought with taxpayer money at risk of going to waste. He said stopping work on diseases like syphilis and H.I.V. would allow new outbreaks to spread.
“The H.I.V. epidemic is going to explode again as a result of these actions,” said Dr. Spinelli, who added that he was speaking only for himself, not his university. “It’s devastating for the communities affected.”
Despite a recent emphasis on the downsides of transitioning, federal officials canceled several grants examining the potential risks of gender-affirming hormone therapy. The projects looked at whether hormone therapy could, for example, increase the risk of breast cancer, cardiovascular disease, altered brain development or H.I.V.
Other terminated grants examined ways of addressing mental illness in transgender people, who now make up about 3 percent of high school students and report sharply higher rates of persistent sadness and suicide attempts.
For Dr. Edwards, of the University of Michigan, funding was halted for a clinical trial looking at how online mentoring might reduce depression and self-harm among transgender teens, one of six studies of hers that were canceled.
Another examined interventions for the families of L.G.B.T.Q. young people to promote more supportive caregiving and, in turn, reduce dating violence and alcohol use among the young people.
The N.I.H. categorizes research only by certain diseases, making it difficult to know how much money the agency devotes to L.G.B.T.Q. health. But a report in March estimated that such research made up less than 1 percent of the N.I.H. portfolio over a decade.
The Times sought to understand the scale of terminated funding for L.G.B.T.Q. medical research by reviewing the titles and, in many cases, research summaries for each of the 669 grants that the Trump administration said it had canceled in whole or in part as of early May.
Beyond grants related to L.G.B.T.Q. people and the diseases and treatments that take a disproportionate toll on them, The Times included in its count studies that were designed to recruit participants from sexual and gender minority groups.
It excluded grants related to illnesses like H.I.V. that were focused on non-L.G.B.T.Q. patients.
While The Times examined only N.I.H. research grants, the Trump administration is also ending or considering ending L.G.B.T.Q. programs elsewhere in the federal health system. It has proposed, for example, scrapping a specialized suicide hotline for L.G.B.T.Q. young people.
The research cuts stand to hollow out a field that in the last decade had not only grown larger, but also come to encompass a wider range of disease threats beyond H.I.V.
Already, scientists said, younger researchers are losing jobs in sexual and gender minority research and scrubbing their online biographies of evidence that they ever worked in the field.
Five grants obtained by Brittany Charlton, a professor at the Harvard School of Public Health, have been canceled, including one looking at sharply elevated rates of stillbirths among L.G.B.T.Q. women.
Ending research on disease threats to gender and sexual minority groups, she said, would inevitably rebound on the entire population. “When other people are sick around you, it does impact you, even if you may think it doesn’t,” she said.
Irena Hwang contributed reporting.

Science
Are salmon sperm facials really good for your skin?

Just when it seemed that the skincare industry had exhausted itself with absurd products and cyborgian procedures, Kim Kardashian brought a new one into the cultural consciousness. In the summer of 2024, Kim Kardashian announced on “The Kardashians” that she had salmon sperm injected into her face, spurring reactions of glee and intrigue that echoed from Rodeo Drive to TikTok.
Salmon sperm facials — which are sometimes called salmon DNA facials for civility’s sake — have become the latest addition to med spa menus across Los Angeles. Formula Fig in Culver City and West Hollywood recently added what is called “the longevity treatment,” which is its take on the popular facial, for $550. Done by Dorfman, a Beverly Hills-based med spa that boasts a celebrity client list, offers the procedure for $750. Kanodia Med Spa, also Beverly Hills-based, offers the facials starting at $1,000.
The procedure is performed through microneedling, which forms channels in the skin before the product is applied topically to the face. Using salmon DNA as an injectable is not yet FDA-approved, so doctors and med spas apply it in conjunction with microneedling and laser treatments. (The substance itself carries an orange-ish tint.) The procedure promises youthful, smooth skin and has been rapidly gaining popularity, thanks partly to endorsements on social media and by celebrities like Jennifer Aniston and Charli XCX.
The idea to use salmon sperm for regeneration is older than you might think. The study of salmon DNA for wound healing was originally pioneered in Italy in the 1980s, said Dr. Zakia Rahman, a clinical professor at Stanford’s School of Dermatology. In the last few years, there has been a resurgence of scientific interest in the substance as a beauty treatment in Korea.
In fact, many doctors source salmon DNA from there. Dr. Donald Yoo, a facial plastic surgeon in Beverly Hills, uses a substance called Rejuran, which is procured from one ocean-side factory in a beachfront town in Gangneung, Korea. In October of last year, he visited the factory during the salmon spawning season to witness the extraction process, which kills the salmon as the DNA is removed.
“During the tour, they showed us the streams where the salmon were captured, the factory where they process the salmon DNA, and actually had us handle some of the live salmon prior to processing,” he says.
Dr. Yoo argues that the uncanniness of salmon sperm is what has made the procedure so popular. His office in Beverly Hills offers the treatment for a starting price of $850.
“There’s a little bit of that shock factor involved,” says Dr. Yoo. “The reason that it’s growing is the fact that science has given it a good, strong basis.”
What basis is that? It begins with polynucleotides, which are fragments of DNA derived from salmon sperm. They were previously used in wound healing after clinical studies showed that they accelerated the tissue repair process. Salmon DNA, as it turns out, shares striking similarities with human DNA, causing it to stimulate collagen production, according to a 2022 peer-reviewed study in the journal Marine Drugs.
“It decreases inflammation,” says Dr. Yoo. “It promotes cell proliferation and blood vessel proliferation.”
When applied to the face, it can result in a soft, radiant, even-toned complexion. For years, scientists in Europe and South Korea have performed clinical studies of salmon DNA on skin to investigate its effect on collagen reproduction. One study conducted on wound healing in mice showed that administering polynucleotides expedited healing and collagen density.
However, despite the growing interest in this treatment, Dr. Rahman is not convinced of its efficacy.
“You have to be careful before jumping on a trend to see if it’s scientifically valid,” said Dr. Rahman.
After reviewing the scientific research, she explains that because of how the nucleotides function on the cell level, they can potentially be harmful to patients with rosacea and can actually cause some inflammation within the cells.
She notes that, when it comes to absorption, polynucleotides are also relatively large, as opposed to more commonly used skin treatment ingredients like retinoids and vitamin C.
“The reason why retinoids and vitamin C work so well is that they’re very small and they can penetrate the skin,” says Dr. Rahman. “So this, if you were just to apply it topically, probably wouldn’t get absorbed.”
From a scientific perspective, it’s not clear that salmon DNA has the potential benefits that are advertised, she said, adding that established methods still yield the best results.
“If you’re using a topical retinoid or topical vitamin C, they’re much less expensive,” she says. “A lot of the laser treatments that we do, which are FDA-cleared for things like collagen stimulation and resurfacing of the skin, are actually much more cost-effective.”
“Do we really want to kill more salmon for their gonads?”
— Dr. Zakia Rahman, Stanford School of Dermatology clinical professor
She also has sustainability concerns. After all, salmon sperm is finite.
“Do we really want to kill more salmon for their gonads?” she asks.
Nevertheless, the trend has become widespread in Europe and South Korea, and in the last year, it has developed a loyal fan base in the U.S. On Instagram, the hashtag #salmonspermfacial has over 5,000 posts featuring before-and-after photos. On TikTok, viral testimonials about salmon DNA facials rack up hundreds of thousands of likes.
Jorian Palos discovered salmon DNA facials after searching for a way to lessen her eye bags and discoloration. She tried the treatment at a med spa chain called Skin Station in Orange County. She said the process was slightly disquieting.
“It was painful, just because it’s salmon semen essentially going under your eye.”
Though she was happy with her results, the recovery was also intense.
“My face was bruised under my eyes for about a week,” she said. “It turned purple, and then it turned yellow.”
Shirel Swissa did not have as an intense recovery. She routinely microneedles and vouches for the treatment.
“Right now, my skin is the smoothest and clearest it’s been in forever,” she says. “There’s no texture. It also helps with my active acne.”
As for the sperm element, Swissa is unbothered: “It smells a tiny bit fishy. It’s not overpowering, but it’s tolerable.”
Dr. Yoo says it’s good to be skeptical of the latest health trend, but predicts that, based on the results he’s seen, salmon sperm facials will stick around.
“It’s an exploding field,” he said.
No pun intended.
Science
Behind a Museum Door, These Beetles Are Eating Flesh for Science

Deep in the labyrinth of the American Museum of Natural History, past the giant suspended blue whale and the first floor’s Alaska brown bears, is an unobtrusive locked door. On it, there is a small sign.
“Bug Colony.”
Behind the door, accessible only to a handful of museum employees, thousands of flesh-eating dermestid beetles toil around the clock handling a task of specimen preparation that even the museum’s best trained specialists cannot.
They eat the meat off animal skeletons, leaving only clean bones behind.
Since many skeletons are too fine to be cleaned by human hands, the museum’s osteological preparation team turns to the six-legged staffers to prepare them for research and display.
The work is carried out in three gray wooden boxes the size of footlockers that house the colony. They are lined with stainless steel and their flip-up tops reveal beetles swarming the earthly remains of various small animals, mostly birds. They feast upon the gobbets of flesh clinging to the carcasses.
The room is pervaded by the soft, crackling sound of gnawing. “It sounds like something frying, or Rice Krispies when you add milk,” said Rob Pascocello, the colony’s tender.
The beetles are tiny enough — just a few millimeters long — to crawl into the recesses of the smallest animals and nibble away without affecting delicate skeletal structures, said Scott Schaefer, who oversees the museum’s collection of more than 30 million specimens and objects.
“They do the fine, detailed work that cannot be done by hand, because it’s so delicate,” Mr. Schaefer said. “It’s gentler than boiling a specimen or soaking it in chemicals or acid.”
Museum officials say the ravenous colony has processed most of the bird collections’ more than 30,000 skeleton specimens over the decades, plus countless other forms of carrion. “They get into the small crevices and, if left unchecked, keep eating until there’s nothing left to eat,” Mr. Schaefer said.
On a recent weekday, Paul Sweet, collection manager for the ornithology department, stood in the Bug Room, and in the interest of scientific precision pointed out that its name was imprecise.
True bugs, known to their fans as the Hemiptera order, have mouthparts that pierce and suck. Beetles — Coleoptera — are typically cylindrical and have mouthparts that chew.
The colony had gone to town with those mouthparts to reduce a once-lustrous pink flamingo to a humble bone bundle. A regal snowy owl was similarly picked clean. Then there was the small skeleton in a canister, with bones tinier than toothpicks.
“That’s a songbird,” said Mr. Pascocello.
Dermestid beetles are scavengers often found in the wild on animal carcasses, and in the nests, webs and burrows of animals.
Museum officials told The New York Times in 1979 that their dermestid colony had remained self-sustaining since being brought over from Africa in the 1930s. Mr. Sweet said the current group has been around for his entire 35 years at the museum, but could not say for sure if they were the original colony’s descendants.
Either way, since a beetle’s life is only about six months, “they’re all kissing cousins,” said Mr. Pascocello. He said that while the museum was closed during the coronavirus pandemic, he “kept a backup colony in my bedroom.”
On this day, Mr. Sweet was looking to skeletonize a northern gannet, a sea bird recovered from Midland Beach on Staten Island. It had been skinned, dried, and trimmed of most of its flesh by researchers before it was handed over to the colony for finishing work.
Within minutes, the carcass was swarmed. The beetles can pick clean a small bird within a couple of days, but may need two weeks for larger skeletons like the gannet.
Mr. Pascocello once served the beetles an orangutan; Mr. Sweet once gave them an emu. But the size of the beetles’ boxes is a factor. Larger specimens must be served piecemeal, like the carcass of a feisty Cuban crocodile known as Fidel, obtained from the Bronx Zoo in 2005.
Before the pristine skeletons are boxed and cataloged, they are soaked in water and frozen for days to kill remaining beetles or eggs.
The beetles are not a threat to humans, but an infestation of the museum’s specimen collection would be disastrous. Keeping the beetles well fed discourages them from wandering away, as does a strip of Vaseline toward the top of their boxes and a sticky floor section across the room’s doorway.
If the supply of specimens should stall, Mr. Pascocello keeps some chicken around as emergency food. Mr. Sweet said he offered the colony pigs’ feet during the pandemic because it was the cheapest bone meat at the supermarket.
The gourmandising of the beetles is a reminder that important science is not always conducted in gleaming, hygienic laboratories. On the door, under the “Bug Colony” sign, is a handwritten addendum:
“Bad odors emanating from behind this door is normal.”
Science
Researchers find drinking water is safe in Eaton, Palisades burn areas as utilities lift last 'do not drink' order

Scientists have released some of the first independent test results confirming that drinking water in fire-affected areas around Altadena and the Pacific Palisades is largely free of harmful contaminants, as an Altadena utility lifted the last “do not drink” notice left in the burn zones.
Researchers with the LA Fire HEALTH Study released results on Friday from 53 homes spread across the burn areas and the more than three miles surrounding them. They found only one with a toxic substance at dangerous levels: at one home, the water contained benzene, a known carcinogen, at concentrations slightly above the state’s allowable level of 1 part per billion.
The findings add to mounting evidence that the affected area’s drinking water is safe. In March, Caltech professor Francois Tissot’s team found no lead levels above the U.S. Environmental Protection Agency’s limit in the tap water of the 43 homes they tested in Altadena and surrounding communities. Separately, UCLA professor Sanjay Mohanty’s group found no concerning levels of heavy metals or potentially harmful “forever” chemicals in 45 homes tested in the Palisades.
Experts noted that LA Fire HEALTH Study’s elevated benzene level — at 1.6 ppb — remains below the federal limit of 5 ppb and would likely drop below 1 ppb once the homeowner follows the utilities’ recommendation to run all faucets in the entire house for at least five minutes to flush contaminants out of the lines before using the tap water.
The state’s limit of 1 ppb equates to no more than a two-in-one-million chance of a resident developing cancer from a lifetime exposure to the contaminant at that level, according to the State Water Resources Control Board. For higher, short-term exposures to benzene, the U.S. EPA says exposure to over 200 ppb for more than a day could have negative, non-cancer health consequences for children.
“I’m optimistic from these results,” said Chris Olivares, a professor of civil and environmental engineering at the University of California, Irvine, who has led the tap water-testing part of the LA Fire HEALTH Study. “The major takeaway, I think, is the importance of flushing.”
Andrew Whelton — a professor of civil and environmental engineering at Purdue University and a pioneer in the field of post-fire water contamination and remediation — attributes the quick and successful restoration of safe drinking water to the hard work of local utilities and state regulators, which followed a post-fire playbook Whelton and others developed in the wake of the 2017 Tubbs fire in Santa Rosa, 2018 Camp fire in Paradise, and subsequent fires throughout Colorado in 2021 and Hawaii in 2023.
The way dangerous volatile organic compounds, like benzene, could contaminate water supplies after a wildfire wasn’t well known or studied until a Santa Rosa resident reported a strong smell of gasoline — a signature indicator of benzene — when turning on their kitchen faucet for the first time after the 2017 fire.
Scientists and public health officials raced to understand and solve the problem. They found benzene levels as high as 40,000 ppb, and it took a year to restore safe water.
After the Camp fire, scientists found levels over 900 ppb, which took eight months to remediate.
After the L.A. County fires, the Los Angeles Department of Water and Power found one instance of benzene at 71.3 ppb. The utility worked around the clock to restore safe water, first by closing roughly 4,800 open connections at fire hydrants and destroyed homes to restore water pressure, then continuously flushing water out of the system to push out contaminants. As they went, they tested and retested until benzene levels dropped to near-zero.
LADWP — with the approval of the State Water Resources Control Board — lifted its “do not drink” notice on March 7, exactly two months after the Palisades fire broke out. Two of the three smaller customer-owned utilities in Altadena, Lincoln Avenue Water Co. and Rubio Cañon Land and Water Assn. — which also detected benzene in their systems after the fires — quickly followed. The third, Las Flores Water Co., lifted the last “do not drink” notice on May 9.
Las Flores had registered the highest benzene levels of all the utilities: 440 ppb from a sample collected on April 10.
The LA Fire HEALTH Study team tested roughly eight homes within each burn area and over a dozen in adjacent communities between February and April while the testing and flushing process was ongoing.
The results are some of the first from the LA Fire HEALTH Study’s broad-ranging, privately funded effort between nearly a dozen academic and medical institutions, to understand the health consequences of the L.A. County fires over the course of 10 years.
Outside the burn areas, no homes the team sampled exceeded the state’s allowable limit for benzene or any of the other two dozen volatile organic compounds for which the group tested. And inside the burn areas, benzene was the only contaminant that exceeded the state’s allowable limits.
Although the utilities have worked for months to flush contaminants out of the labyrinth of pipes shuttling water from reservoirs to private properties, it’s homeowners who are responsible for finishing out the job and flushing the pipes on their own properties.
The researchers stressed that the one benzene exceedance — found in Lincoln Avenue’s service area one week after the utility’s “do not drink” notice was lifted — is a reminder that residents should follow the utilities’ guidance for safe water use once returning home.
“Lincoln Avenue Water Company’s top priority is to provide safe and reliable drinking water to the community. Through extensive testing, we have established that our system is in compliance with all state and federal water quality standards,” said Lincoln Avenue general manager Jennifer Betancourt Torres, in a statement to The Times.
“It’s important to emphasize that samples taken from inside the home are considered a representation of the residential plumbing and not the water being delivered,” she said.
The utilities and water safety experts say residents should first flush all of their lines — every faucet and spigot, both hot and cold, for at least five minutes. They should also run all appliances and fixtures, like dishwashers and washing machines, once with hot water before using. Two batches of ice from a fridge icemaker should be discarded.
Each utility is providing detailed, up-to-date guidance for their customers on their respective websites, including LADWP, Rubio Cañon, Lincoln Avenue and Las Flores.
Staff writer Ian James contributed to this report.
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