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Oregon health officials investigate rare brain disease blamed for two deaths

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Oregon health officials investigate rare brain disease blamed for two deaths

Health officials in Hood River County, Ore., are investigating three cases of a rare and fatal brain disease known as Creutzfeldt-Jakob disease.

Two people have died and a third person is showing symptoms consistent with the disease. The disease has been confirmed in one of the deceased through an autopsy; the other two cases are considered probable, according to a statement from the Hood River County Health Department.

All three cases were diagnosed in the last eight months. County health officials declined to provide particulars about the individuals, such as their age, gender or town of residence.

“At this time, there is no identifiable link between these three cases,” a Hood River County statement said. The county has a population of about 24,000.

Creutzfeldt-Jakob disease is a neurodegenerative disorder caused by misfolded proteins known as prions. These prions lead to rapid brain deterioration, resulting in severe neurological symptoms and death. Although the disease is known for its sporadic occurrence, clusters raise concerns among public health officials about potential environmental or dietary exposure.

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Symptoms include issues with memory, walking, coordination, speech and behavior changes, according to experts. It does not spread through the air, water, touch or social contact, according to Hood River County health officials.

The disease is considered incurable and is always fatal. Roughly 350 cases are diagnosed in the United States every year, according to the National Institutes of Health.

The disease is rare in people, affecting roughly 1.4 people per million. However, because the disease takes years to develop, any person’s chance of developing the disease is closer to 1 in 5,000 or 6,000, said Michael Geschwind, a professor of neurology at UC San Francisco in the Memory and Aging Center.

The disease is similar to chronic wasting disease, or CWD, which is also a prion-fueled disease, and was detected for the first time in wild deer in California and Washington last year.

CWD was first reported in 1967, in a captive Colorado deer. It has since spread to deer in 36 states. There are no known cases of the disease in Oregon wildlife.

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For decades there has been concern that CWD could move into human populations through the ingestion of contaminated meat.

That’s because in the 1980s, a prion disease in sheep, known as scrapies — which humans do not seem to get — moved into cows, and soon people throughout the United Kingdom, France and elsewhere were becoming infected with mad cow disease, or bovine spongiform encephalopathy.

Since then, public health officials from the Centers for Disease Control and Prevention and several states have been paying close attention to clusters of Creutzfeldt-Jakob disease — investigating outbreaks to determine whether infected deer, elk or moose meat was involved.

They — and researchers from other agencies, such as the U.S. Geological Survey’s National Wildlife Health Center — also have been monitoring wild deer populations and keeping tabs on hunters who may have been exposed.

Although widespread geographically throughout the United States and Canada, the disease is considered relatively rare in wild populations of deer, elk and moose, said Brian Richardson, the emerging-disease coordinator at the USGS wildlife center.

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“It may well be [in Oregon], but it’s hard to find rare events,” he said.

To date, there are no known incidents of people acquiring a prion disease by consuming deer, elk or moose meat, said Geschwind, the UCSF professor.

He said roughly 85% to 90% of Creutzfeldt-Jakob cases are considered sporadic, with no identified cause or source of infection. In 10% to 15% of the cases, the disease appears to be genetically inherited — with some people acquiring mutations associated with the disease.

However, there have been a few cases in which sources of infection or contamination have been identified, and almost all of them were from a medical mishap.

Prions are notoriously difficult to inactivate or destroy — withstanding standard sterilization techniques — and can remain intact for months and years on a surface, Geschwind said.

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In a small number of cases, he said, people acquired the disease as a result of contaminated and improperly cleaned surgical equipment. In a few other cases, it was acquired by people who used products — such as growth hormone, or who received corneal transplants — derived, inadvertently, from infected cadavers.

It’s these proteins’ durability and longevity that have many researchers worried. Studies have shown that deer that harbor the disease can pass the infectious prions to other deer through saliva, blood, urine and feces.

“So, if the animal is licking a plant or licking a salt lick, for example, and another animal comes along and licks that plant or salt lick, then that might be a way of spreading the disease,” Geschwind said.

In addition, the decomposing body of a deer that died of the disease can infect the surrounding environment where the animal expired — potentially contaminating plants, seeds, fungi and soil, Richardson said.

He said not only is there the issue of surface contamination, but also research has shown that the proteins can “be taken up via rootlets and deposited in aerial plant tissues. Whether these plants contribute to chronic wasting disease transmission and what type of risk these plants pose to humans remain open questions.”

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Geschwind noted that the work done by federal researchers to better understand the disease, provide diagnostic autopsies on presumptive cases, monitor wildlife and investigate clusters has provided a level of protection for the American public, which could be destabilized by proposed cuts to federal agencies.

“The idea of cutting government funding of rare disease is very short-sighted, because even though CJD is a rare disease, what we have learned from prion diseases has implications for all neurodegenerative diseases,” he said, noting Alzheimer’s disease, frontotemporal dementia, Parkinson’s disease and multiple system atrophy.

“All these diseases act in a prion-like manner in which normal proteins misfold, and those misfolded proteins cause the cells to not work partly and lead to disease,” he said. “But the basic mechanism that we’ve learned from this very rare disease applies to diseases that are thousands of times more common. To get rid of the research? It’d be a very grave mistake.”

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Why new dads shouldn’t panic about low testosterone

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Why new dads shouldn’t panic about low testosterone

Three months after his son was born, Kevin Maguire felt alone.

It was 2019. He had recently moved to Barcelona with his wife and daughter and was working on marketing projects for Fortune 500 companies. The birth of his son, Bodhi, should have been a joyous event. But Maguire, now 43, became sad and irritable, and didn’t want to be around his newborn. He withdrew from family and friends, often playing video games late into the night or finding excuses to get out of the house.

“I would take the dog out for a walk,” Maguire said. “I wanted to get far away enough that I wouldn’t bump into anyone I knew and I would just sit and cry.”

Desperate for answers, he entered his symptoms online. Maguire, author of the recently published book “The New Fatherhood: Why Everything They Told You About Being a Dad Is Wrong, and How Embracing It Will Transform Your Life,” knew to look for signs of the “baby blues” in his wife. But he was surprised by articles that said men could experience postpartum depression too. The diagnosis resonated and he began writing about his condition and the trials of fatherhood on Substack.

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New dads face psychological pressures, from sleepless nights to sky-high bills, which can contribute to postpartum depression. So can shifting hormone levels.

“One thing I found in my lab’s research is that when new dads have really low levels of testosterone, they might report more symptoms of postpartum depression,” said Darby Saxbe, a professor of psychology at USC and author of the recently published “Dad Brain: The New Science of Fatherhood and How It Shapes Men’s Lives.”

While hormonal shifts can create challenges, they also help men adapt to fatherhood, Saxbe explained. Several hormones can spike in men when they become dads, including oxytocin, linked to better relationship quality; vasopressin, associated with emotional bonding; and prolactin, which promotes lactation in women and caregiving behavior in guys.

New dads can also experience a decline in testosterone. According to a 2011 paper from University of Notre Dame professor Lee Gettler, part of the largest study on fatherhood and testosterone ever conducted, men averaged around a 25% drop in testosterone after becoming fathers.

While dads have reasons to be concerned by plummeting levels of testosterone, a modest dip isn’t necessarily a disaster — in fact, it can make men better parents and partners.

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“We often get invested in the idea that men should always have the highest possible levels of testosterone,” Saxbe said. “What the research tells us is a little more nuanced. You really want flexibility. You want a hormonal system that can adapt to the different demands of your life.”

The prospect of a decline might scare soon-to-be fathers, especially those on TikTok and Instagram, where accounts push the idea that having “high T” is the key to being a “real man,” according to a recent study in the journal Social Science & Medicine.

Influencers stand to profit persuading men there’s a widespread “masculinity crisis,” the researchers found, noting that 72% of the accounts they analyzed had a stake in testosterone supplements and treatments.

But studies show more testosterone isn’t always better. “We found that when dads have higher testosterone, even before birth, they’re less invested [than men with lower testosterone] in co-parenting a few months after birth,” Saxbe said. High T fathers were more stressed from parenting than their lower T counterparts, and had partners who were less satisfied in their romantic relationships.

This jibes with the challenge hypothesis, which says, in multiple species, testosterone levels rise when males battle for attention from potential mates and go down when it’s time to take care of the young.

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While a small decline can be adaptive, dads face mental health risks when their testosterone drops too low.

There is no “normal” level of testosterone, said Dr. Jesse Mills, director of the Men’s Clinic at UCLA Health. Experts recommend that men should consider treatment if their levels dip below 300 nanograms per deciliter (ng/dL). But men metabolize testosterone in different ways, meaning a healthy level for one might be low for another.

“If a new dad comes to me and his testosterone is 298 [ng/dL], he’s below the threshold,” Mills said. “But if he has zero symptoms and everything else is going great — he’s over the moon with his new child, he’s so happy — that’s not somebody I’m going to treat with testosterone.”

He notes that the drop in testosterone fathers experience can partly be attributed to the stresses that come with a new kid: less sleep, a poor diet and fewer trips to the gym. That means there are precautions that expectant fathers can take that don’t involve testosterone replacement therapy (TRT).

Still, while some guys with low testosterone levels might not need TRT, others in the “normal” range could benefit from treatment. (Dads who want another kid soon, beware. Mills notes that testosterone replacement therapy can take a man’s sperm count to zero.)

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Both Mills and Saxbe stress that men should be paying attention to symptoms of low testosterone — such as depression and low libido — rather than trying to reach or maintain an ideal number. They also agree that tending to mental health concerns is hugely important for new fathers.

Eventually, after Maguire researched his condition, he recovered after time spent meditating, exercising and bonding with his son.

“A lot of new dads don’t realize how much they’re struggling because they feel ashamed or because they don’t realize it’s common shortly after the birth of a baby,” Saxbe said.

When they struggle, fathers can fixate on testosterone because that’s what modern culture tells them will make them feel better. And sometimes testosterone replacement therapy works. But Saxbe stresses a lot of men could use psychotherapy or support groups that bring dads together, as well as more time bonding with loved ones in general.

“The thing that predicts a man’s well-being and longevity is the quality of his relationships with other people,” said Saxbe. “You can be the world’s best weightlifter. You can have a low body-fat percentage. You can be killing it at work. Those things don’t predict how happy you’re going to be at 80.”

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Video: NASA Announces Artemis III Crew

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Video: NASA Announces Artemis III Crew

new video loaded: NASA Announces Artemis III Crew

transcript

transcript

NASA Announces Artemis III Crew

NASA announced the crew of Artemis III mission, which will fly to low-Earth orbit to test rendezvous and docking maneuvers with one or two lunar landers.

“I am excited to welcome you as the next crew in the Artemis journey to successfully return to the moon — this time to stay.” “I’m honored by the role that I’ve been given. I’m also very humbled by the task in front of us. But first and foremost, I’m grateful.” “So with that, the Artemis II crew, comrade, hands you the baton. You got the controls.” “As you know, we had a significant anomaly at our Launch Complex 36A on May 28. We’ve redoubled our efforts and are moving forward.”

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NASA announced the crew of Artemis III mission, which will fly to low-Earth orbit to test rendezvous and docking maneuvers with one or two lunar landers.

By Alisa Shodiyev Kaff

June 9, 2026

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Santa Monica Mountains’ last steelhead trout survived the Palisades fire — and even had babies

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Santa Monica Mountains’ last steelhead trout survived the Palisades fire — and even had babies

Scientists feared the Santa Monica Mountains’ last remaining steelhead trout were dead, smothered by debris flows unleashed by the Palisades fire.

But the endangered fish surprised them: A team of biologists recently spotted 30 of the rare trout — and 21 babies — in Topanga Creek.

“There was a lot of happy dancing in the creek,” said Rosi Dagit, principal conservation biologist for the Resource Conservation District of the Santa Monica Mountains, which works with public and private landowners to conserve natural resources.

That’s because the steelhead here are endangered, at both the state and federal levels. Once, they swam in most streams of the Santa Monicas, but their numbers plummeted amid overfishing and coastal development. Increasingly frequent wildfire has further stressed their habitat. Topanga Creek, a biodiversity hot spot, is home to their last known population in the mountains that stretch from the Hollywood Hills to Point Mugu in Ventura County.

The trout that were spotted, including this one, are part of a distinct Southern California population that’s listed as endangered at the state and federal levels.

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(RCDSMM Stream Team)

The California Department of Fish and Wildlife spearheaded a complex mission to rescue trout threatened by the Palisades fire that sparked in January 2025.

Time was of the essence. The fire hadn’t yet been fully contained. But rain was on the way, which would sweep massive amounts of sediment from the denuded hillsides into the water. Fish are often killed this way.

Crews stunned the fish with electricity, scooped them up in buckets, trucked them to a hatchery and ultimately moved them to Arroyo Hondo Creek in Santa Barbara County.

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Within days, Topanga Creek was choked with mud. Some assumed the fish left behind were goners.

But in March, the conservation district’s team found four. The following month, when water conditions were clearer, they saw more.

“These fish continue to amaze me,” said Kyle Evans, environmental program manager for the state Department of Fish and Wildlife, who had seen the damage to the creek. “I had seen populations get wiped out in similar situations. So when I heard, I was thrilled.”

Evans surmises the fish that survived were in an area of the creek where less charred material and sediment were swept in.

“These fish likely hunkered down, were hiding under some rocks or places to try to get away from the main concentration of flow,” he said. “And luckily they weren’t buried.”

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The ones that were spotted were fairly small, around 6 to 14 inches. Rainbow trout and steelhead trout are the same species, but with different lifestyles. If the fish remain in freshwater, they’ll be considered rainbows. However, they can migrate to the ocean and become steelhead, where they typically grow larger before returning to their natal waters to spawn.

Topanga Creek hasn’t fully recovered from the damage it sustained, but scientists say it’s looking better. Surveys last year were “so depressing,” Dagit said, with very few animals, and stretches that were essentially transformed into flat roads from all the sediment buildup. Some of the riparian canopy burned right down to the creek.

Then came 32 inches of rain over the last nine months, scouring out and moving sediment, creating deeper pools. Dagit said they recently found newt egg masses for the first time in years, as well as a few adult newts and many frogs. Plants that provide cover are starting to recover.

She provided photos comparing certain pools last year and this year, some dramatically transformed. In September 2025, the Shrine Pool could have been an overgrown hiking trail. This April, it was filled with shallow water.

Shrine Pool, Sept. 2025, left, and the same location, April 2026, right.

The Shrine Pool in September 2025, left, and the same location in April 2026, right, with RCDSMM’s Isaac Yelchin donning a wetsuit.

(RCDSMM Stream Team)

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Topanga Creek is home to another endangered fish, the small but hardy northern tidewater goby, often described as cute. Not long before the trout operation, Dagit led a rescue of hundreds of these fish too. Many were repatriated to the lagoon at the mouth of the creek in a moving ceremony last June.

There’s still the matter of what to do with the trout that were moved to Santa Barbara County last year. Evans would like to bring them home to the Santa Monicas at some point, but isn’t sure if it will happen. On one hand, they could bolster the small, genetically isolated surviving population. On the other, they might inadvertently bring in a disease or bacteria. There is some time to decide. Evans estimates the creek still needs to recover for two to three more years.

For now, the fish are functioning fine in their adopted creek. Experts worried the trauma wrought by the move would disrupt their spawning process, but they had babies that spring. This year, they spawned again.

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