Science
Omicron coronavirus variant seen as a clarion call to vaccinate the globe
For nearly a yr since COVID-19 vaccines first turned out there, many main well being authorities have urged rich nations and vaccine manufacturing corporations to prioritize inoculating folks in poorer Southern Hemisphere nations to assist forestall troublesome new variants from rising.
Since then, vaccines have change into available in america, Western Europe and different developed areas of the world. However in Africa, the place the brand new Omicron coronavirus variant was first detected in latest days, vaccines stay extraordinarily tough to come back by and simply 7% of the inhabitants is absolutely inoculated, in contrast with 42% of the worldwide inhabitants and 58% of america.
“With this degree of vaccine inequality, variants like Omicron are fully predictable,” mentioned Matthew Kavanagh, director of the International Well being Coverage and Politics Initiative at Georgetown’s O’Neill Institute on Friday. “Boosters and journey bans won’t defend People. We are going to proceed to dwell in concern till we repair the vaccine inequalities.”
On Friday, specialists on the World Well being Group categorized Omicron as a “variant of concern,” the group’s most critical class.
Scientists warning towards drawing conclusions in regards to the variant’s capabilities too shortly: It’ll take days and even weeks for researchers to run checks and pore over knowledge, based on Tim Schacker, the vice dean of analysis on the College of Minnesota’s medical faculty.
Nonetheless, the WHO’s announcement is critical: The “variant of concern” label is often reserved for these with mutations that might doubtlessly make the virus extra contagious or virulent, or might render defenses resembling vaccinations much less efficient.
Some earlier variants haven’t lived as much as the preliminary alarm. However the Omicron variant has greater than 50 mutations, greater than half of them on the virus’ spike protein, the important thing goal of vaccines and subsequent antibodies. Michael Osterholm, an epidemiologist on the College of Minnesota who served on President Biden’s COVID-19 advisory board throughout his transition into workplace, referred to as it “certainly a lot, rather more regarding than [the] Delta” variant, which now accounts for nearly all COVID-19 instances in america.
“Of all of the variants we have now seen to this point, that is most likely the best public well being concern we’ve had,” he mentioned. “It might evade some or all the immunity we have now from earlier infections and vaccines. We simply don’t know.”
Whereas a number of jabs and even boosters have considerably lowered the possibilities of critical sickness or loss of life to those that have taken benefit throughout america and far of Europe, massive unvaccinated populations within the growing world present way more alternatives for the coronavirus to evolve into new varieties that might threaten the effectiveness of vaccines.
Africa’s two most populous international locations, Nigeria and Ethiopia, each have vaccination charges beneath 2%. Until the speed rises dramatically, international variants will probably be thought-about inevitable.
COVAX, the WHO initiative to ship vaccines to low-income international locations, has struggled with setbacks, together with underwhelming investments by rich international locations and a surge in Delta instances that saved photographs from leaving India, the place lots of them are manufactured and have been distributed. The marketing campaign is anticipating to produce virtually half a billion new doses by the top of the yr, however has to this point delivered solely a few third of what it had anticipated.
Some public well being specialists fear a few discouraging cycle wherein new variants immediate rich international locations to order extra boosters, depleting the manufacturing capability for first and second doses wanted in largely unvaccinated areas.
Greater than 60 growing international locations, led by India and South Africa, have proposed briefly suspending vaccine patents and different mental property to allow nations to supply their very own vaccines, driving up stock. Biden, underneath strain to assist vaccinate folks in poorer nations, many within the Southern Hemisphere, has mentioned he helps such a waiver. He repeated his stance Friday, saying that Omicron “reiterates the significance of transferring on this shortly.”
However drug corporations and the European Union oppose such a transfer as a result of they are saying it might discourage pharmaceutical funding, and america has completed little to push negotiations ahead.
“For the final yr, wealthy international locations have hoarded doses and paid excessive costs for boosters in hopes that may hold them protected” as an alternative of specializing in international vaccination, Kavanagh mentioned. He identified that a lot of the cutting-edge vaccine improvement credited to non-public corporations in 2020 was funded by U.S. taxpayers and used copious quantities of presidency analysis.
“It’s lengthy overdue to share this publicly funded know-how with the world so Africa, Asia and Latin America could make vaccines,” he mentioned.
Osterholm counters that though vaccine manufacturing capability is finite, it’s “not useful or correct” to recommend that america booster rollout had nice bearing on the emergence of Omicron. There are different extraordinary challenges to vaccination campaigns in distant areas, together with the necessity for refrigerated transport, coordinated groups of well being employees, and — as evidenced in rich and poor nations alike — public confidence within the effort. Widespread vaccination relies upon upon each provide and demand.
“It’s not simply a difficulty of handing folks vaccines,” mentioned Anne Rimoin, an epidemiologist at UCLA.
The USA, Britain, Australia and different rich nations had been swift late this week to limit journey from southern Africa, triggering backlash from critics who say their vaccine hoarding contributed to the emergence within the first place.
And whereas journey bans in some instances purchase officers time to coordinate a public well being response, they usually come too late. Omicron has already been detected in locales together with Hong Kong, Belgium, Israel and Britain. “The cat’s out of the bag,” Rimoin mentioned.
She and different scientists credit score South Africa for a powerful surveillance system that detected, analyzed and reported the brand new variant to the WHO shortly.
The USA “wouldn’t have caught it at almost this velocity,” Osterholm mentioned. “Those that consider South Africa as contributing to an issue: You should be grateful to them.”
As soon as researchers know the way present vaccine formulation stack up towards Omicron, subsequent steps will change into clearer. Producers may have to change the components, and officers would wish to organize a plan to ship new ones.
Within the meantime, public well being specialists urge international leaders to behave upon what’s already clear: With out extra vaccines in southern Africa, the virus will retain thousands and thousands of alternatives to duplicate and adapt.
“I’ve been saying for months and months that the way forward for this pandemic will come down to 2 points: waning immunity and new variants,” Osterholm mentioned. “What you see right here is that, whereas so many individuals around the globe are completed with this pandemic, the virus isn’t completed with us.”
Science
Cluster of farmworkers diagnosed with rare animal-borne disease in Ventura County
A cluster of workers at Ventura County berry farms have been diagnosed with a rare disease often transmitted through sick animals’ urine, according to a public health advisory distributed to local doctors by county health officials Tuesday.
The bacterial infection, leptospirosis, has resulted in severe symptoms for some workers, including meningitis, an inflammation of the brain lining and spinal cord. Symptoms for mild cases included headaches and fevers.
The disease, which can be fatal, rarely spreads from human to human, according to the U.S. Centers for Disease Control and Prevention.
Ventura County Public Health has not given an official case count but said it had not identified any cases outside of the agriculture sector. The county’s agriculture commissioner was aware of 18 cases, the Ventura County Star reported.
The health department said it was first contacted by a local physician in October, who reported an unusual trend in symptoms among hospital patients.
After launching an investigation, the department identified leptospirosis as a probable cause of the illness and found most patients worked on caneberry farms that utilize hoop houses — greenhouse structures to shelter the crops.
As the investigation to identify any additional cases and the exact sources of exposure continues, Ventura County Public Health has asked healthcare providers to consider a leptospirosis diagnosis for sick agricultural workers, particularly berry harvesters.
Rodents are a common source and transmitter of disease, though other mammals — including livestock, cats and dogs — can transmit it as well.
The disease is spread through bodily fluids, such as urine, and is often contracted through cuts and abrasions that contact contaminated water and soil, where the bacteria can survive for months.
Humans can also contract the illness through contaminated food; however, the county health agency has found no known health risks to the general public, including through the contact or consumption of caneberries such as raspberries and blackberries.
Symptom onset typically occurs between two and 30 days after exposure, and symptoms can last for months if untreated, according to the CDC.
The illness often begins with mild symptoms, with fevers, chills, vomiting and headaches. Some cases can then enter a second, more severe phase that can result in kidney or liver failure.
Ventura County Public Health recommends agriculture and berry harvesters regularly rinse any cuts with soap and water and cover them with bandages. They also recommend wearing waterproof clothing and protection while working outdoors, including gloves and long-sleeve shirts and pants.
While there is no evidence of spread to the larger community, according to the department, residents should wash hands frequently and work to control rodents around their property if possible.
Pet owners can consult a veterinarian about leptospirosis vaccinations and should keep pets away from ponds, lakes and other natural bodies of water.
Science
Political stress: Can you stay engaged without sacrificing your mental health?
It’s been two weeks since Donald Trump won the presidential election, but Stacey Lamirand’s brain hasn’t stopped churning.
“I still think about the election all the time,” said the 60-year-old Bay Area resident, who wanted a Kamala Harris victory so badly that she flew to Pennsylvania and knocked on voters’ doors in the final days of the campaign. “I honestly don’t know what to do about that.”
Neither do the psychologists and political scientists who have been tracking the country’s slide toward toxic levels of partisanship.
Fully 69% of U.S. adults found the presidential election a significant source of stress in their lives, the American Psychological Assn. said in its latest Stress in America report.
The distress was present across the political spectrum, with 80% of Republicans, 79% of Democrats and 73% of independents surveyed saying they were stressed about the country’s future.
That’s unhealthy for the body politic — and for voters themselves. Stress can cause muscle tension, headaches, sleep problems and loss of appetite. Chronic stress can inflict more serious damage to the immune system and make people more vulnerable to heart attacks, strokes, diabetes, infertility, clinical anxiety, depression and other ailments.
In most circumstances, the sound medical advice is to disengage from the source of stress, therapists said. But when stress is coming from politics, that prescription pits the health of the individual against the health of the nation.
“I’m worried about people totally withdrawing from politics because it’s unpleasant,” said Aaron Weinschenk, a political scientist at the University of Wisconsin–Green Bay who studies political behavior and elections. “We don’t want them to do that. But we also don’t want them to feel sick.”
Modern life is full of stressors of all kinds: paying bills, pleasing difficult bosses, getting along with frenemies, caring for children or aging parents (or both).
The stress that stems from politics isn’t fundamentally different from other kinds of stress. What’s unique about it is the way it encompasses and enhances other sources of stress, said Brett Ford, a social psychologist at the University of Toronto who studies the link between emotions and political engagement.
For instance, she said, elections have the potential to make everyday stressors like money and health concerns more difficult to manage as candidates debate policies that could raise the price of gas or cut off access to certain kinds of medical care.
Layered on top of that is the fact that political disagreements have morphed into moral conflicts that are perceived as pitting good against evil.
“When someone comes into power who is not on the same page as you morally, that can hit very deeply,” Ford said.
Partisanship and polarization have raised the stakes as well. Voters who feel a strong connection to a political party become more invested in its success. That can make a loss at the ballot box feel like a personal defeat, she said.
There’s also the fact that we have limited control over the outcome of an election. A patient with heart disease can improve their prognosis by taking medicine, changing their diet, getting more exercise or quitting smoking. But a person with political stress is largely at the mercy of others.
“Politics is many forms of stress all rolled into one,” Ford said.
Weinschenk observed this firsthand the day after the election.
“I could feel it when I went into my classroom,” said the professor, whose research has found that people with political anxiety aren’t necessarily anxious in general. “I have a student who’s transgender and a couple of students who are gay. Their emotional state was so closed down.”
That’s almost to be expected in a place like Wisconsin, whose swing-state status caused residents to be bombarded with political messages. The more campaign ads a person is exposed to, the greater the risk of being diagnosed with anxiety, depression or another psychological ailment, according to a 2022 study in the journal PLOS One.
Political messages seem designed to keep voters “emotionally on edge,” said Vaile Wright, a licensed psychologist in Villa Park, Ill., and a member of the APA’s Stress in America team.
“It encourages emotion to drive our decision-making behavior, as opposed to logic,” Wright said. “When we’re really emotionally stimulated, it makes it so much more challenging to have civil conversation. For politicians, I think that’s powerful, because emotions can be very easily manipulated.”
Making voters feel anxious is a tried-and-true way to grab their attention, said Christopher Ojeda, a political scientist at UC Merced who studies mental health and politics.
“Feelings of anxiety can be mobilizing, definitely,” he said. “That’s why politicians make fear appeals — they want people to get engaged.”
On the other hand, “feelings of depression are demobilizing and take you out of the political system,” said Ojeda, author of “The Sad Citizen: How Politics is Depressing and Why it Matters.”
“What [these feelings] can tell you is, ‘Things aren’t going the way I want them to. Maybe I need to step back,’” he said.
Genessa Krasnow has been seeing a lot of that since the election.
The Seattle entrepreneur, who also campaigned for Harris, said it grates on her to see people laughing in restaurants “as if nothing had happened.” At a recent book club meeting, her fellow group members were willing to let her vent about politics for five minutes, but they weren’t interested in discussing ways they could counteract the incoming president.
“They’re in a state of disengagement,” said Krasnow, who is 56. She, meanwhile, is looking for new ways to reach young voters.
“I am exhausted. I am so sad,” she said. “But I don’t believe that disengaging is the answer.”
That’s the fundamental trade-off, Ojeda said, and there’s no one-size-fits-all solution.
“Everyone has to make a decision about how much engagement they can tolerate without undermining their psychological well-being,” he said.
Lamirand took steps to protect her mental health by cutting social media ties with people whose values aren’t aligned with hers. But she will remain politically active and expects to volunteer for phone-banking duty soon.
“Doing something is the only thing that allows me to feel better,” Lamirand said. “It allows me to feel some level of control.”
Ideally, Ford said, people would not have to choose between being politically active and preserving their mental health. She is investigating ways to help people feel hopeful, inspired and compassionate about political challenges, since these emotions can motivate action without triggering stress and anxiety.
“We want to counteract this pattern where the more involved you are, the worse you are,” Ford said.
The benefits would be felt across the political spectrum. In the APA survey, similar shares of Democrats, Republicans and independents agreed with statements like, “It causes me stress that politicians aren’t talking about the things that are most important to me,” and, “The political climate has caused strain between my family members and me.”
“Both sides are very invested in this country, and that is a good thing,” Wright said. “Antipathy and hopelessness really doesn’t serve us in the long run.”
Science
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