Science
New Vaccine Findings Pose Tough Questions for Parents of Young Children
For American dad and mom, significantly these with younger youngsters, the final couple of months have been dizzying and past irritating.
In early February, federal regulators introduced that they’d consider Pfizer-BioNTech’s coronavirus vaccine for the youngest youngsters — solely to scrap that plan 10 days later, citing doubts concerning the vaccine’s effectiveness in that age group.
Quickly after, scientists reported that the vaccine was solely weakly protecting towards an infection with the Omicron variant amongst youngsters aged 5 to 11 and that it appeared to supply little protection towards average Covid sickness amongst adolescents aged 12 to 17.
On Monday, citing these information, Florida’s surgeon basic declared that wholesome youngsters needn’t be immunized, recommendation that Jen Psaki, the White Home press secretary, referred to as “deeply disturbing.”
By all of it, specialists have continued to endorse vaccines, noting that whereas the Omicron variant could possibly penetrate immune defenses and infect individuals, the vaccines nonetheless stop extreme sickness and dying — and will accomplish that for years.
The Facilities for Illness Management and Prevention discovered that file numbers of youngsters below 5 had been hospitalized throughout the Omicron surge, underscoring the necessity for vaccines for these youngsters. However the company has since stated that 90 % of People can safely cease carrying masks in public indoor areas, even in faculties with younger youngsters.
Who may blame dad and mom for feeling bewildered?
“The half that’s complicated is like there’s not any clear, proper reply,” stated Anne Gonzalez, a 41-year-old mom of two who manages volunteers for a big non secular nonprofit in St. Louis. “I’ve come to the purpose that each one I can do is what I believe is true for my household.”
Thankfully, the approaching weeks ought to carry some readability. Each Pfizer and Moderna plan to report outcomes from trials of their vaccines in younger youngsters. The outcomes, if optimistic, ought to result in a brand new spherical of regulatory overview, maybe as early as April, that will properly enable vaccinations for tens of hundreds of thousands of kids.
However these findings will arrive because the Omicron variant fades in the US, complicating parental selections about whether or not to vaccinate youngsters.
Fewer than one in 4 youngsters aged 5 to 11 at the moment are totally vaccinated. Greater than half of adolescents 12 to 17 are totally vaccinated, however solely about 12 % have obtained a booster dose. These percentages are even decrease in rural areas of the US.
Youngsters are much less prone to expertise sickness, so the stability of threat and profit was by no means the identical as for adults. And by now, as a lot as 95 % of the nation has a point of safety from the virus due to vaccines or prior an infection, in response to latest information from the C.D.C.
Consultants fear that the newest findings have made it much more difficult to influence some dad and mom to immunize their youngsters.
“We must be upset with the info — we want it may very well be higher,” stated Luciana Borio, a former appearing chief scientist on the Meals and Drug Administration. “However within the close to time period, it’s essential for fogeys to nonetheless vaccinate youngsters.”
The nation should see a surge within the fall or winter, and the perfect safety for kids might be to have had a minimum of two photographs earlier than then, she stated.
The vaccines are persevering with to stop extreme illness and dying, even with the Omicron variant. That pattern is especially clear at hospitals, stated Dr. James Campbell, a doctor on the College of Maryland Faculty of Drugs and a member of the American Academy of Pediatrics committee on infectious illnesses.
Amongst his pediatric sufferers who have been sick sufficient to wish a mechanical ventilator or die, “each single certainly one of them was unvaccinated,” Dr. Campbell stated.
A Dosing Conundrum
The latest research recommend that the issue shouldn’t be a lot the vaccine because the dose.
Within the trials in adults in 2020, vaccine producers made finest guesses on the proper dose and opted for brief intervals between the photographs to guard individuals as rapidly as doable throughout the preliminary surge.
The Pfizer-BioNTech and Moderna vaccines proved to be protected and powerfully protecting in scientific trials and have been speedily licensed to be used. However the trials in youngsters have been sophisticated by the arrival of the Delta and Omicron variants, and the vaccine seemed to be much less protecting in youngsters aged 2 to 4.
For the time being, the Pfizer-BioNTech vaccine is the one one licensed for kids. (The vaccines made by Moderna and Johnson & Johnson are licensed just for adults.)
Within the Pfizer trials, adolescents aged 12 to 17 got 30 micrograms, the identical dose given to adults. However youngsters aged 5 to 11 obtained 10 micrograms, and people 6 months to five years previous obtained simply three micrograms.
These doses might have been too low to evoke an enough and lasting response. However federal officers who’ve seen the info instructed The New York Occasions that increased doses produced too many fevers in youngsters.
What to do when you possibly can’t administer a dose excessive sufficient to defend youngsters towards the Omicron variant due to negative effects? That’s the issue that scientists and federal officers at the moment are wrestling with.
Pfizer and BioNTech at the moment are testing a 3rd dose in youngsters below 12 to find out whether or not it may ship the extent of safety that two doses couldn’t. The F.D.A. continues to be evaluating the Moderna vaccine to be used in youngsters 6 to 11. Final week, the company rejected an utility for authorization of the Indian-made vaccine Covaxin for kids.
There are different Covid vaccines, like these made by Novavax and Sanofi, that will end up to work properly in youngsters. Federal well being officers ought to think about all of those choices and take a look at whether or not a unique dose or an extended interval between doses would enhance the immune response, specialists stated.
“It appears to me that vaccines for kids are taking longer than they need to, given the significance of defending that inhabitants,” Dr. Borio stated. “The earlier we re-energize our seek for protected and efficient vaccines for kids, the higher off we’ll be.”
Masks in Faculties
The disappointing findings, together with the receding Omicron surge, have drastically sophisticated coverage selections for native well being officers.
Countering Florida’s suggestions, Louisiana and California would require schoolchildren to be immunized by fall 2022, and the District of Columbia set a deadline of March 1 for college students 12 and older to be totally vaccinated.
Different states might undertake comparable insurance policies however are probably to take action provided that the F.D.A. grants the vaccine full approval to be used in schoolchildren, stated Hemi Tewarson, govt director on the Nationwide Academy for State Well being Coverage, a nonpartisan group.
“For lots of them, that’s going to be key for requiring vaccines as a mandate,” she stated.
A faculty vaccine mandate would ease the fears of many households with youngsters who’ve medical vulnerabilities.
Practically each member of Heather Keever’s household, together with her son, Wesley, 14, has coronary heart illness, hypertension and kidney illness. However as a result of they aren’t technically immunocompromised, they haven’t certified for lodging at work or in school, stated Ms. Keever, 42, a marketing consultant in suburban Chicago.
“They neglect that there’s a few of us who simply actually can’t take the masks off,” a minimum of till the charges fall a lot additional, she stated. “I felt like I didn’t matter and I wasn’t essential and I used to be arguably disposable. And I nonetheless do.”
Some scientists, too, have stated they’d proceed to put on masks till the numbers dip due to the chance of an infection.
As a result of the youngest youngsters haven’t but been vaccinated, “I’d be very hesitant to ask a toddler under 5 to take away masks indoors,” stated Akiko Iwasaki, an immunologist at Yale College who research lengthy Covid, the cluster of signs that may persist lengthy after the acute an infection is resolved.
Given the muddled outcomes on the effectiveness of vaccines and the blended messages on the advantages of masks, households are weighing dangers on their very own — and coming to very totally different conclusions.
Jennifer Steinberg, a administration marketing consultant in Wilmington, Del., has two daughters who break up their time together with her and their immunocompromised father.
“Sure, nice, it protects towards extreme sickness,” Ms. Steinberg stated of the vaccine. “But when your youngsters are nonetheless going to get contaminated, this can be a enormous disruption to household lives. I’m in all probability going to remain masked for the foreseeable future.”
Katie Sunderland of Arlington, Va., has lengthy been prepared to surrender masks. If her youngsters, 7 and 5, do grow to be contaminated, “that’s a trade-off I’m OK with if they’re able to unmask and see faces,” she stated.
“I’m not satisfied that carrying a masks would considerably scale back the chance of getting Covid anyway — particularly not the kind of masks I see most youngsters carrying,” Ms. Sunderland, 37, stated. “It doesn’t make sense to me to impede my youngsters’ growth for that very, very, very low threat.”
However many different dad and mom are nonetheless not sure of what to do. Ms. Gonzalez has a niece and nephew who’ve congenital coronary heart defects and issues with lung capability, and she’s going to proceed to put on masks to guard them, she stated.
But when her son’s college drops the masks requirement, “we don’t know what we’re going do but.”
Science
Cluster of farmworkers diagnosed with rare animal-borne disease in Ventura County
A cluster of workers at Ventura County berry farms have been diagnosed with a rare disease often transmitted through sick animals’ urine, according to a public health advisory distributed to local doctors by county health officials Tuesday.
The bacterial infection, leptospirosis, has resulted in severe symptoms for some workers, including meningitis, an inflammation of the brain lining and spinal cord. Symptoms for mild cases included headaches and fevers.
The disease, which can be fatal, rarely spreads from human to human, according to the U.S. Centers for Disease Control and Prevention.
Ventura County Public Health has not given an official case count but said it had not identified any cases outside of the agriculture sector. The county’s agriculture commissioner was aware of 18 cases, the Ventura County Star reported.
The health department said it was first contacted by a local physician in October, who reported an unusual trend in symptoms among hospital patients.
After launching an investigation, the department identified leptospirosis as a probable cause of the illness and found most patients worked on caneberry farms that utilize hoop houses — greenhouse structures to shelter the crops.
As the investigation to identify any additional cases and the exact sources of exposure continues, Ventura County Public Health has asked healthcare providers to consider a leptospirosis diagnosis for sick agricultural workers, particularly berry harvesters.
Rodents are a common source and transmitter of disease, though other mammals — including livestock, cats and dogs — can transmit it as well.
The disease is spread through bodily fluids, such as urine, and is often contracted through cuts and abrasions that contact contaminated water and soil, where the bacteria can survive for months.
Humans can also contract the illness through contaminated food; however, the county health agency has found no known health risks to the general public, including through the contact or consumption of caneberries such as raspberries and blackberries.
Symptom onset typically occurs between two and 30 days after exposure, and symptoms can last for months if untreated, according to the CDC.
The illness often begins with mild symptoms, with fevers, chills, vomiting and headaches. Some cases can then enter a second, more severe phase that can result in kidney or liver failure.
Ventura County Public Health recommends agriculture and berry harvesters regularly rinse any cuts with soap and water and cover them with bandages. They also recommend wearing waterproof clothing and protection while working outdoors, including gloves and long-sleeve shirts and pants.
While there is no evidence of spread to the larger community, according to the department, residents should wash hands frequently and work to control rodents around their property if possible.
Pet owners can consult a veterinarian about leptospirosis vaccinations and should keep pets away from ponds, lakes and other natural bodies of water.
Science
Political stress: Can you stay engaged without sacrificing your mental health?
It’s been two weeks since Donald Trump won the presidential election, but Stacey Lamirand’s brain hasn’t stopped churning.
“I still think about the election all the time,” said the 60-year-old Bay Area resident, who wanted a Kamala Harris victory so badly that she flew to Pennsylvania and knocked on voters’ doors in the final days of the campaign. “I honestly don’t know what to do about that.”
Neither do the psychologists and political scientists who have been tracking the country’s slide toward toxic levels of partisanship.
Fully 69% of U.S. adults found the presidential election a significant source of stress in their lives, the American Psychological Assn. said in its latest Stress in America report.
The distress was present across the political spectrum, with 80% of Republicans, 79% of Democrats and 73% of independents surveyed saying they were stressed about the country’s future.
That’s unhealthy for the body politic — and for voters themselves. Stress can cause muscle tension, headaches, sleep problems and loss of appetite. Chronic stress can inflict more serious damage to the immune system and make people more vulnerable to heart attacks, strokes, diabetes, infertility, clinical anxiety, depression and other ailments.
In most circumstances, the sound medical advice is to disengage from the source of stress, therapists said. But when stress is coming from politics, that prescription pits the health of the individual against the health of the nation.
“I’m worried about people totally withdrawing from politics because it’s unpleasant,” said Aaron Weinschenk, a political scientist at the University of Wisconsin–Green Bay who studies political behavior and elections. “We don’t want them to do that. But we also don’t want them to feel sick.”
Modern life is full of stressors of all kinds: paying bills, pleasing difficult bosses, getting along with frenemies, caring for children or aging parents (or both).
The stress that stems from politics isn’t fundamentally different from other kinds of stress. What’s unique about it is the way it encompasses and enhances other sources of stress, said Brett Ford, a social psychologist at the University of Toronto who studies the link between emotions and political engagement.
For instance, she said, elections have the potential to make everyday stressors like money and health concerns more difficult to manage as candidates debate policies that could raise the price of gas or cut off access to certain kinds of medical care.
Layered on top of that is the fact that political disagreements have morphed into moral conflicts that are perceived as pitting good against evil.
“When someone comes into power who is not on the same page as you morally, that can hit very deeply,” Ford said.
Partisanship and polarization have raised the stakes as well. Voters who feel a strong connection to a political party become more invested in its success. That can make a loss at the ballot box feel like a personal defeat, she said.
There’s also the fact that we have limited control over the outcome of an election. A patient with heart disease can improve their prognosis by taking medicine, changing their diet, getting more exercise or quitting smoking. But a person with political stress is largely at the mercy of others.
“Politics is many forms of stress all rolled into one,” Ford said.
Weinschenk observed this firsthand the day after the election.
“I could feel it when I went into my classroom,” said the professor, whose research has found that people with political anxiety aren’t necessarily anxious in general. “I have a student who’s transgender and a couple of students who are gay. Their emotional state was so closed down.”
That’s almost to be expected in a place like Wisconsin, whose swing-state status caused residents to be bombarded with political messages. The more campaign ads a person is exposed to, the greater the risk of being diagnosed with anxiety, depression or another psychological ailment, according to a 2022 study in the journal PLOS One.
Political messages seem designed to keep voters “emotionally on edge,” said Vaile Wright, a licensed psychologist in Villa Park, Ill., and a member of the APA’s Stress in America team.
“It encourages emotion to drive our decision-making behavior, as opposed to logic,” Wright said. “When we’re really emotionally stimulated, it makes it so much more challenging to have civil conversation. For politicians, I think that’s powerful, because emotions can be very easily manipulated.”
Making voters feel anxious is a tried-and-true way to grab their attention, said Christopher Ojeda, a political scientist at UC Merced who studies mental health and politics.
“Feelings of anxiety can be mobilizing, definitely,” he said. “That’s why politicians make fear appeals — they want people to get engaged.”
On the other hand, “feelings of depression are demobilizing and take you out of the political system,” said Ojeda, author of “The Sad Citizen: How Politics is Depressing and Why it Matters.”
“What [these feelings] can tell you is, ‘Things aren’t going the way I want them to. Maybe I need to step back,’” he said.
Genessa Krasnow has been seeing a lot of that since the election.
The Seattle entrepreneur, who also campaigned for Harris, said it grates on her to see people laughing in restaurants “as if nothing had happened.” At a recent book club meeting, her fellow group members were willing to let her vent about politics for five minutes, but they weren’t interested in discussing ways they could counteract the incoming president.
“They’re in a state of disengagement,” said Krasnow, who is 56. She, meanwhile, is looking for new ways to reach young voters.
“I am exhausted. I am so sad,” she said. “But I don’t believe that disengaging is the answer.”
That’s the fundamental trade-off, Ojeda said, and there’s no one-size-fits-all solution.
“Everyone has to make a decision about how much engagement they can tolerate without undermining their psychological well-being,” he said.
Lamirand took steps to protect her mental health by cutting social media ties with people whose values aren’t aligned with hers. But she will remain politically active and expects to volunteer for phone-banking duty soon.
“Doing something is the only thing that allows me to feel better,” Lamirand said. “It allows me to feel some level of control.”
Ideally, Ford said, people would not have to choose between being politically active and preserving their mental health. She is investigating ways to help people feel hopeful, inspired and compassionate about political challenges, since these emotions can motivate action without triggering stress and anxiety.
“We want to counteract this pattern where the more involved you are, the worse you are,” Ford said.
The benefits would be felt across the political spectrum. In the APA survey, similar shares of Democrats, Republicans and independents agreed with statements like, “It causes me stress that politicians aren’t talking about the things that are most important to me,” and, “The political climate has caused strain between my family members and me.”
“Both sides are very invested in this country, and that is a good thing,” Wright said. “Antipathy and hopelessness really doesn’t serve us in the long run.”
Science
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