Science
How drug overdose deaths surpassed 100,000 in one year
The drug disaster that has gripped the U.S. for years hit a milestone through the pandemic. Greater than 100,000 Individuals died of overdoses within the one-year interval main as much as April, an virtually 30% leap from the prior yr, in keeping with knowledge launched this week by the Nationwide Heart for Well being Statistics. That startling determine exceeds the variety of site visitors and gun fatalities mixed.
How did that occur? The Occasions spoke to Sam Quinones, who chronicled the drug commerce within the 2015 ebook “Dreamland: The True Story of America’s Opiate Epidemic,” and most lately explored the evolution of the epidemic in his new ebook “The Least of Us: True Tales of America and Hope within the Time of Fentanyl and Meth.”
Quinones is a former Occasions reporter. This interview has been edited for readability.
Sam, that is the primary time we’ve seen the variety of overdose deaths in a single yr exceed 100,000. It’s straightforward to think about how the pandemic performed a task on this surge — driving up nervousness and despair, reducing off entry to remedy. However there appears to be a little bit of a paradox right here: a disaster that was exacerbated by COVID-19, but in addition obscured by it.
Sure, and in addition utterly deflated by it. Consideration to the disaster was actually rising till February 2020, after which all the main target shifted — I’m not saying wrongly — to the pandemic. The issue was, it was at this very second that the Mexican trafficking world had achieved one thing that no different traffickers had achieved within the historical past of our nation: protecting the nation with probably the most lethal and mind-mangling medicine we’ve ever seen. It had been constructing for years in the direction of that. It simply so occurred that we went into isolation on the very second when these medicine hit their apex.
You’re speaking about artificial medicine, and notably meth and fentanyl, which will be as much as 100 occasions as highly effective as morphine. How does the efficiency of those medicine play into the evolving drug disaster?
These overdose figures are unprecedented as a result of the scenario on the road is as properly. By no means within the trendy historical past of drug use — so round World Struggle II, let’s say — have you ever seen a necessity for the drug-trafficking world to combine medicine to make a revenue. Not with crack, PCP, cocaine — this all comes able to promote, proper? Now, to ensure that the trafficking world to make the lottery-winning sort of earnings it expects to make, it has to combine that stuff.
They’re mixing with meth, mixing with cocaine, and now we’re seeing stories of blending with marijuana. All people promoting is aware of that you just simply add fentanyl to your combine — whether or not you’re promoting cocaine or meth, it doesn’t matter — and fairly quickly, you’re going to get a fentanyl addict who will purchase from you each single day.
We’re dwelling in a really, very totally different world. It was once that shifts would happen over a long time: the ’70s have been depressants; the ’80s was crack, stimulants; the ’90s, properly, you didn’t actually know. And so now it’s all collectively and all on the similar time — in catastrophic portions.
Let me ask you about that, as a result of, in terms of one thing so addicting, I typically surprise in regards to the cyclical relationship between provide and demand. As individuals get hooked, it looks like the artificial nature of those merchandise mitigates the limitations to mass-production.
Proper. You may make these year-round, supplied that you’ve got entry to the chemical compounds. These artificial medicine don’t want seasons: You don’t want 4 months to make 50 kilos of methamphetamine, you want a couple of week. And when you have the chemical compounds, you can also make these 50 kilos again and again and again and again.
With methamphetamine, it’s now not restricted by one precursor that’s tough to copy. You may make ghastly portions with many various chemical procedures or hacks, proper? You may make it this manner, you can also make it that approach. The chemical compounds are totally different, however they’re all simply obtainable, they’re all industrial, they’re authorized. In fact, most of them are very poisonous — however there’s lye, cyanide, hydrochloric acid, sulfuric acid. There’s some ways of constructing these items.
Because of this, the worth drop for methamphetamine in lots of areas is 80% or extra. Within the Nashville space, for instance, methamphetamine was $12.50 for an oz.. Now it’s $2.25.
What about fentanyl?
To start with, the quantity that it is advisable to make an enormous, large revenue is definitely comparatively small. And it’s pretty straightforward to make. However with fentanyl, there’s one other situation. At first, it was Chinese language firms sending fentanyl over proper within the mail — you purchase it on the darkish internet, they usually ship you a kilo. Nevertheless it’s extremely unlikely we’d ever be capable of hit the provision of fentanyl we’re seeing now with mailed packages from China.
That amount is because of the truth that it’s now the Mexican trafficking world making it, with these limitless chemical compounds from ports on the Pacific coast of Mexico, and funneling it by border crossings among the many tens of millions of vehicles and vehicles that cross backwards and forwards to america yearly. The shift was away from China to Mexico, the place the chemical compounds are coming in in large numbers.
Geographically talking, if that’s the place the merchandise are coming from, the place are they going? As we have a look at the overdose knowledge from the previous yr, it appears to be touching virtually each nook of the U.S.
Take into consideration this: Should you drive coast to coast on the freeways, you will notice that company America has supplied virtually an identical choices all throughout the nation. It doesn’t matter the place you might be — you’ll find the Applebees, the Cracker Barrel, the identical Hampton Inns and Motel 6s and Shell gasoline stations.
That’s what the Mexican trafficking world has achieved with these two medicine specifically — fentanyl and methamphetamine. You will get them in Kentucky, you will get them in Los Angeles, you will get them in Oregon. They’ve constructed up huge distribution networks all throughout the nation. That, too, is unprecedented.
So, this isn’t the mom-and-pop store, and even the In-N-Out. It’s the McDonald’s, proper?
The McDonald’s or the Walmart, yeah.
Are you able to communicate a bit bit in regards to the the demographics we’re seeing within the overdose deaths? Numerous us nonetheless consider the disaster as primarily a rural, white situation. However these numbers are reflecting the shift towards extra various victims.
Once I wrote “Dreamland,” there have been no nonwhites concerned. It was outstanding for that very purpose — by no means had we seen a uniracial drug scourge in our nation, so far as I do know, or definitely nothing on this scale. And it’s nonetheless largely white. that appears to me very clear.
However “The Least of Us” definitely introduced African Individuals into the combination for the primary time in my reporting. African Individuals are dying of opioid overdoses as a result of African American sellers are determining the identical factor as some other vendor: I can put fentanyl into my cocaine. And if I do, I’ll have a fentanyl person fairly quickly. In my ebook, I discuss this in some depth. The chapter that I write about this focuses across the first African American man to die within the metropolis of Akron, which was one of many first cities to see the arrival of fentanyl. Mikey Tanner lived 10 years scuffling with a cocaine habit, however didn’t reside greater than a month or two after fentanyl hit the drug provide.
It was years in the past — within the early days of fentanyl — nevertheless it portended one thing bigger, which was that the drug sellers within the African American neighborhood, like each different drug vendor throughout America, have been starting to determine that when you added fentanyl to no matter you’re promoting, you get a far, much more devoted buyer. The unfavourable, in fact, is that you just often get a useless physique.
It’s what most definitely occurred to the comedian in Venice Seashore in early September, and most definitely occurred to Michael Ok. Williams, the good actor from “The Wire.” Individuals initially assume they’re on cocaine, they usually die on these items.
I’m curious the way you assume federal or state responses might want to change in gentle of this new knowledge. There’s lengthy been loads of hype about rising entry to naloxone and selling its use. However what’s your view concerning how finest to handle this — cracking down, or easing up?
I’m afraid to reply to this query, as a result of I’d need to go on for some time. And never as a result of I’ve all of the solutions. However the thought of decriminalizing medicine — when these medicine are fentanyl and meth — appears to me to be the peak of misguided compassion. It’s not form and merciful, it’s a demise sentence, and it’s really devastating.
The medicine have modified, however our considering hasn’t. Philosophies that have been born of one other drug period need to be reassessed; the concept there isn’t any function for legislation enforcement in all that is foolhardy.
The time has come to know: There is no such thing as a attaining readiness for remedy once you’re on the road hooked on fentanyl and artificial meth. You’ll by no means be prepared for remedy earlier than these medicine kill you. Finally, fentanyl will kill everyone who makes use of it.
Science
FDA sets limits for lead in many baby foods as California disclosure law takes effect
The U.S. Food and Drug Administration this week set maximum levels for lead in baby foods such as jarred fruits and vegetables, yogurts and dry cereal, part of an effort to cut young kids’ exposure to the toxic metal that causes developmental and neurological problems.
The agency issued final guidance that it estimated could reduce lead exposure from processed baby foods by about 20% to 30%. The limits are voluntary, not mandatory, for food manufacturers, but they allow the FDA to take enforcement action if foods exceed the levels.
It’s part of the FDA’s ongoing effort to “reduce dietary exposure to contaminants, including lead, in foods to as low as possible over time, while maintaining access to nutritious foods,” the agency said in a statement.
Consumer advocates, who have long sought limits on lead in children’s foods, welcomed the guidance first proposed two years ago, but said it didn’t go far enough.
“FDA’s actions today are a step forward and will help protect children,” said Thomas Galligan, a scientist with the Center for Science in the Public Interest. “However, the agency took too long to act and ignored important public input that could have strengthened these standards.”
The new limits on lead for children younger than 2 don’t cover grain-based snacks such as puffs and teething biscuits, which some research has shown contain higher levels of lead. And they don’t limit other metals such as cadmium that have been detected in baby foods.
The FDA’s announcement comes just one week after a new California law took effect that requires baby food makers selling products in California to provide a QR code on their packaging to take consumers to monthly test results for the presence in their product of four heavy metals: lead, mercury, arsenic and cadmium.
The change, required under a law passed by the California Legislature in 2023, will affect consumers nationwide. Because companies are unlikely to create separate packaging for the California market, QR codes are likely to appear on products sold across the country, and consumers everywhere will be able to view the heavy metal concentrations.
Although companies are required to start printing new packaging and publishing test results of products manufactured beginning in January, it may take time for the products to hit grocery shelves.
The law was inspired by a 2021 congressional investigation that found dangerously high levels of heavy metals in packaged foods marketed for babies and toddlers. Baby foods and their ingredients had up to 91 times the arsenic level, up to 177 times the lead level, up to 69 times the cadmium level, and up to five times the mercury level that the U.S. allows to be present in bottled or drinking water, the investigation found.
There’s no safe level of lead exposure for children, according to the U.S. Centers for Disease Control and Prevention. The metal causes “well-documented health effects,” including brain and nervous system damage and slowed growth and development. However, lead occurs naturally in some foods and comes from pollutants in air, water and soil, which can make it impossible to eliminate entirely.
The FDA guidance sets a lead limit of 10 parts per billion for fruits, most vegetables, grain and meat mixtures, yogurts, custards and puddings and single-ingredient meats. It sets a limit of 20 parts per billion for single-ingredient root vegetables and for dry infant cereals. The guidance covers packaged processed foods sold in jars, pouches, tubs or boxes.
Jaclyn Bowen, executive director of the Clean Label Project, an organization that certifies baby foods as having low levels of toxic substances, said consumers can use the new FDA guidance in tandem with the new California law: The FDA, she said, has provided parents a “hard and fast number” to consider a benchmark when looking at the new monthly test results.
But Brian Ronholm, director of food policy for Consumer Reports, called the FDA limits “virtually meaningless because they’re based more on industry feasibility and not on what would best protect public health.” A product with a lead level of 10 parts per billion is “still too high for baby food. What we’ve heard from a lot of these manufacturers is they are testing well below that number.”
The new FDA guidance comes more than a year after lead-tainted pouches of apple cinnamon puree sickened more than 560 children in the U.S. between October 2023 and April 2024, according to the CDC.
The levels of lead detected in those products were more than 2,000 times higher than the FDA’s maximum. Officials stressed that the agency doesn’t need guidance to take action on foods that violate the law.
Aleccia writes for the Associated Press. Gold reports for The Times’ early childhood education initiative, focusing on the learning and development of California children from birth to age 5. For more information about the initiative and its philanthropic funders, go to latimes.com/earlyed.
Science
NASA punts Mars Sample Return decision to the next administration
Anyone hoping for a clear path forward this year for NASA’s imperiled Mars Sample Return mission will have to wait a little longer.
The agency has settled on two potential strategies for the first effort to bring rock and soil from another planet back to Earth for study, NASA Administrator Bill Nelson said Tuesday: It can either leverage existing technology into a simpler, cheaper craft or turn to a commercial partner for a new design.
But the final decision on the mission’s structure — or whether it should proceed at all — “is going to be a function of the new administration,” Nelson said. President-elect Donald Trump will take office Jan. 20.
“I don’t think we want the only [Mars] sample return coming back on a Chinese spacecraft,” Nelson said, referencing a rival mission that Beijing has in the works. “I think that the [Trump] administration will certainly conclude that they want to proceed. So what we wanted to do was to give them the best possible options so that they can go from there.”
The call also contained words of encouragement for NASA’s Jet Propulsion Laboratory in La Cañada Flintridge, which leads the embattled mission’s engineering efforts.
“To put it really bluntly, JPL is our Mars center in NASA science,” said Nicky Fox, associate administrator of the Science Mission Directorate. “They are the people who landed us on Mars, together with our industry partners. So they will be moving forward, regardless of which path, with a key role in the Mars Sample Return.”
In April, after an independent review found “near zero probability” of Mars Sample Return making its proposed 2028 launch date, NASA put out a request for alternative proposals to all of its centers and the private sector. JPL was forced to compete for what had been its own project.
The independent review board determined that the original design would probably cost up to $11 billion and not return samples to Earth until at least 2040.
“That was just simply unacceptable,” said Nelson, who paused the mission in late 2023 to review its chances of success.
Ensuing cuts to the mission’s budget forced a series of layoffs at JPL, which let go of 855 employees and 100 on-site contractors in 2024.
The NASA-led option that Nelson suggested Tuesday includes several elements from the JPL proposal, according to a person who reviewed the documents. This leaner, simpler alternative will cost between $6.6 billion and $7.7 billion, and will return the samples by 2039, he said. A commercial alternative would probably cost $5.8 billion to $7.1 billion.
Nelson, a former Democratic U.S. senator from Florida, will step down as head of the space agency when Trump takes office. Trump has nominated as his successor Jared Isaacman, a tech billionaire who performed the first private space walk, who must be confirmed by the Senate.
NASA has not had any conversations with Trump’s transition team about Mars Sample Return, Nelson said. How the new administration will prioritize the project is not yet clear.
“It’s very uncertain how the new administration will go forward,” said Casey Dreier, chief of space policy for the Planetary Society, a Pasadena nonprofit that promotes space research. “Cancellation is obviously still on the table. … It’s hard to game this out.”
Planetary scientists have identified Mars Sample Return as their field’s highest priority in the last three decadal surveys, reports that the National Academies of Sciences, Engineering, and Medicine prepare every 10 years in order to advise NASA.
Successfully completing the mission is “key for the nation’s leadership in space science,” said Bethany L. Ehlmann, a planetary scientist at Caltech in Pasadena. “I hope the incoming administrator moves forward decisively to select a plan and execute. There are extraordinary engineers at JPL and NASA industry partners eager and able to get to work to make it happen.”
Science
Panama Canal’s Expansion Opened Routes for Fish to Relocate
Night fell as the two scientists got to work, unfurling long nets off the end of their boat. The jungle struck up its evening symphony: the sweet chittering of insects, the distant bellowing of monkeys, the occasional screech of a kite. Crocodiles lounged in the shallows, their eyes glinting when headlamps were shined their way.
Across the water, cargo ships made dark shapes as they slid between the seas.
The Panama Canal has for more than a century connected far-flung peoples and economies, making it an essential artery for global trade — and, in recent weeks, a target of President-elect Donald J. Trump’s expansionist designs.
But of late the canal has been linking something else, too: the immense ecosystems of the Atlantic and the Pacific.
The two oceans have been separated for some three million years, ever since the isthmus of Panama rose out of the water and split them. The canal cut a path through the continent, yet for decades only a handful of marine fish species managed to migrate through the waterway and the freshwater reservoir, Lake Gatún, that feeds its locks.
Then, in 2016, Panama expanded the canal to allow supersize ships, and all that started to change.
In less than a decade, fish from both oceans — snooks, jacks, snappers and more — have almost entirely displaced the freshwater species that were in the canal system before, scientists with the Smithsonian Tropical Research Institute in Panama have found. Fishermen around Lake Gatún who rely on those species, chiefly peacock bass and tilapia, say their catches are growing scarce.
Researchers now worry that more fish could start making their way through from one ocean to the other. And no potential invader causes more concern than the venomous, candy-striped lionfish. They are known to inhabit Panama’s Caribbean coast, but not the eastern Pacific. If they made it there through the canal, they could ravage the defenseless local fish, just as they’ve done in the Gulf of Mexico and the Caribbean.
Already, marine species are more than occasional visitors in Lake Gatún, said Phillip Sanchez, a fisheries ecologist with the Smithsonian. They’re “becoming the dominant community,” he said. They’re “pushing everything else out.”
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