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How About Them Apples? Research Orchards Chart a Fruit’s Future.

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How About Them Apples? Research Orchards Chart a Fruit’s Future.

Think about reaching as much as a tree department and plucking an apple that’s unusually tall and slim — a range known as Kandil Snap, native to the Black Sea area. In an adjoining arboreal row, 11 bushes to the north, you’ll discover the equally unique darkish purple Black Oxford apples, resembling giant plums.

Add 1,000-plus extra sorts of the fruit genus Malus, which is bursting with an autumn-themed rainbow of purple, orange, yellow, inexperienced and even purple, to this scene, and also you’re within the Apple Biodiversity Assortment within the Annapolis Valley of Nova Scotia, Canada.

The apples gained’t find yourself in pies or the hampers of autumn leaf peepers. As an alternative, scientists there are engaged on understanding the genetics that end result on this bonanza of apple range, with the final word purpose of bettering the fruit in numerous methods — tastier, heartier, extra disease-resistant and with longer shelf-life within the face of adjusting climates.

“It’s great to have the ability to stroll via what is actually the United Nations of apples and see the world’s genetic range multi functional place,” stated Sean Myles, who began the orchard in 2011, “and that feeling is rapidly changed with an amazing urgency to get all this work finished.”

You may not understand it, however many well-liked apples in grocery shops in recent times — Cosmic Crisps from Washington State, SnapDragons from New York and Honeycrisps, initially from Minnesota — originated with the efforts of scientists analyzing the qualities of various apple varieties and crossbreeding them. With some 7,500 sorts of apple on the planet, there’s loads to find. Future generations of apples in grocery shops could come from analysis orchards just like the one in Nova Scotia, which is among the many latest.

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Dr. Myles didn’t begin out as an apple genes aficionado — he has an allergy to uncooked apples, which make his mouth itch except they’re cooked. He had beforehand labored on human genetics on the Stanford College Faculty of Drugs. Quite than a love of the fruit, his love of his now-wife prompted a transfer to the Annapolis Valley, the place she makes wine. As a result of the area’s fundamental crop was apples, Dr. Myles acquired into the enterprise of apple genes. He joined Dalhousie College’s College of Agriculture in 2011 and acquired a Canada Analysis Chair place with funding to start out the Apple Biodiversity Assortment.

There is no such thing as a world census of all efforts to protect apple range. A 2019 report revealed by the World Crop Variety Belief discovered 40 apple range collections around the globe, with seven established throughout the twenty first century, however as a result of it was not an entire checklist, the Nova Scotia orchard was not included. The report additionally notes that greater than half of the 40 surveyed orchards are in North America or Europe. Solely three are in Central Asia and the Caucasus Area, the place scientists imagine many up to date apple varieties originated.

To make sure higher safety of long-term conservation of the world’s apple range, the report requires a worldwide group of those that domesticate these collections. However right this moment, “we’re definitely a good distance away from having any type of worldwide coordination of apple range upkeep,” Dr. Myles stated.

In america, the U.S. Division of Agriculture manages the nation’s most numerous apple assortment in Geneva, N.Y., which can also be among the many world’s largest, stated Ben Gutierrez, the gathering’s curator (the location consists of grapes and cherries, too). Many of the greater than 5,000 apple varieties are planted in an orchard throughout 30 acres. Tissue from every type of apple is saved in a large freezer in order that if climate or illness harms a selected tree, researchers can reintroduce that selection to the orchard.

Greater than half of the apple supplies in the usD.A. assortment, are wild, with almost 4,000 samples, together with bushes and seeds.

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“Although not instantly interesting from a fruit high quality perspective, these wild apples have great potential for illness resistance, local weather adaptability or different surprising high-value traits and are important for understanding the evolution of Malus species and the domestication historical past of contemporary apples,” Dr. Gutierrez stated.

In Nova Scotia, creating the Apple Biodiversity Assortment was a painstaking six-year course of. It concerned planting 4,000 little bushes, ripping them up after a yr, preserving them in moist sawdust in a large fridge throughout the winter, replanting them throughout the subsequent summer time, then ready for them to mature. Dr. Myles and his colleagues affixed labels with names to each tree and waited.

The Canadians collaborated with the usD.A. orchard in Geneva, the place the main target is conservation, to acquire the uncooked supplies. Having numerous the identical varieties in each locations “provides some perception into how the bushes would carry out in further websites,” Dr. Gutierrez stated. He added that as a result of the Nova Scotia orchard has extra of a analysis focus, it was designed with randomization, replication and different components in thoughts, “to make their knowledge extra related.”

By conserving a various number of apples and finding out the genetic underpinnings of assorted traits, websites just like the one in Nova Scotia assist to broaden the scope of attainable future apples.

Firmer apples. Extra sugary — or extra tart. Apples may even have purple flesh inside — a “modern” development spun off from wild Kazakh apples which can be too bitter to eat, stated Francois Laurens at INRAE, the French nationwide analysis institute for agriculture.

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In terms of cooking up new appears for a fruit that appears totally baked, apples are more durable to work with than many different crops due to the five- to seven-year wait earlier than a tree produces fruit. And earlier than a brand new selection even reaches growers, researchers take about 15 years to breed and check a given apple.

“We’re simply speaking 20 to 25 years from this yr for these new varieties to actually get to shoppers in a giant approach,” stated James Luby, professor of horticultural sciences on the College of Minnesota.

Dr. Luby’s declare to apple fame is his involvement within the Honeycrisp, developed on the College of Minnesota Horticultural Analysis Heart within the Sixties and Nineteen Seventies. He began on the middle in 1982, a couple of decade earlier than the Honeycrisp hit the market within the early Nineteen Nineties. At the moment, he stated, some growers and “most likely some journalists” had been skeptical that new apples had been wanted.

“We knew after we first tasted it that it was one thing very completely different than what was in the marketplace — you realize, that type of explosive crunchiness, breaking flesh, was very completely different,” Dr. Luby stated of the Honeycrisp apple.

Honeycrisp and plenty of different industrial apples originated via a method known as managed hybridization, which incorporates taking pollen from one type of apple tree and placing it on the flower of one other. The cross-pollination produces a hybrid apple, simply as two mother and father produce a toddler who shares each of their genetic traits, stated Susan Okay. Brown, a professor at Cornell College’s Faculty of Integrative Plant Science, who leads the nation’s oldest apple breeding program, additionally in Geneva.

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Some current apple successes from Dr. Brown, the analysis specialist Kevin Maloney and their giant crew of collaborators at Cornell have included the RubyFrost and SnapDragon varieties, which debuted to shoppers in 2013. They had been commercialized in a partnership with Crunch Time Apple Growers of New York.

Firecracker, one other one of many Cornell group’s creations, “was one in all many names prompt by testers and it matched the variability for having an explosion of taste,” Dr. Brown stated.

Different researchers have pursued genetic modification strategies, which alter an current apple selection by inserting genetic materials. Some G.M.O.’s already being offered embody the Arctic Apples, with “Arctic” variations of Fuji, Gala and Granny Smith apples.

Distinct from genetic modification is CRISPR, a method that slices and edits genomes instantly. CRISPR could develop into vital for the way forward for apples and meals typically. For one factor, “once you need to perceive the perform of a gene, you possibly can disrupt it utilizing CRISPR,” stated David Chagne of the New Zealand Institute for Plant and Meals Analysis.

There have been some preliminary successes — an Italian group demonstrated in a 2019 examine that CRISPR may very well be used to cut back susceptibility to fireside blight illness, for instance.

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However CRISPR isn’t a magic paring knife. Some nations comparable to New Zealand don’t enable CRISPR for use for industrial meals, Dr. Chagne stated. One other problem for CRISPR is regenerating a woody plant from a single cell is just not straightforward, Dr. Myles stated.

The Canadian group is entering into the CRISPR sport, however the problem of the apple’s lengthy growth interval additionally stays an impediment: Even when Dr. Myles’s crew could make an edit to a Honeycrisp plant that makes the apple somewhat tastier, it can take 5 years for the primary check fruit to develop up.

“It could be some time earlier than persons are seeing these items on the grocery retailer shelf,” Dr. Myles stated, “however it’s coming down the pipeline for positive. And our group hopes to be those that type of lay the muse for that.”

To characterize apple flavors or to verify the fruits are able to be picked, researchers have to personally pattern them. Considerably like skilled wine tasters, apple specialists “chew, chew, style and spit,” or else they’ll upset their stomachs, Dr. Myles stated.

Sophie Watts, a Dalhousie College doctoral pupil with Dr. Myles’s group, stated she had doubtless tasted about 800 of the orchard’s apples “within the identify of analysis.” The orchard has, for instance, some apples with “hints of banana, citrus fruits and even one known as Cotton Sweet that tastes precisely like cotton sweet,” she stated.

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Samples of the 75 wild apple from the orchard “for essentially the most half, tasted fairly unhealthy” she stated.

Ms. Watts additionally emphasised the Nova Scotia lab’s position in preserving biodiversity. “It’s vital we hold as a lot crop range round in order that we will lean on it to breed new varieties which can be tailored to our altering world,” she stated.

Dr. Myles’s crew has finished primary genetic sequencing of all the bushes within the Apple Biodiversity Assortment, leading to a flurry of publications delving into the genetic underpinnings of apple traits. The group has recognized genes that regulate how a lot apples change whereas they’re saved in storage, for instance.

Nonetheless, Dr. Myles cautions, there’s no single genetic modification that can remodel the apple world.

“I actually want I had that knock-it-out-of-the-park trait,” he stated. “I want we may make it style like a banana and appear to be an avocado. And, you realize, have it yield thrice as a lot and be resistant to each illness.”

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He added, “Whoa, wouldn’t that be superior? However science doesn’t work that approach.”

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Union presses California’s key bird flu testing lab for records

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Union presses California’s key bird flu testing lab for records

The union representing workers at a UC Davis lab that tests and tracks bird flu infections in livestock has sued the university, demanding that records showing staffing levels and other information about the lab’s operations be released to the public.

Workers in the lab’s small biotechnology department had raised concerns late last year about short staffing and potentially bungled testing procedures as cases of avian flu spread through millions of birds in turkey farms and chicken and egg-laying facilities, as well as through the state’s cattle herds.

The University Professional and Technical Employees-CWA Local 9119 said that it requested records in December 2024 in an attempt to understand whether the lab was able to properly service the state’s agribusiness.

But UC Davis has refused to release records, in violation of California’s public records laws, the union alleged in a lawsuit recently filed in Alameda County Superior Court.

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UC Davis spokesperson Bill Kisliuk declined to comment on the lawsuit’s specific allegations.

“The university looks forward to filing our response in court. We are grateful for the outstanding work of the CAHFS lab staff, including UPTE-represented workers, during the 2024 surge in avian flu testing,” Kisliuk said in an email.

UC Davis has previously denied that workplace issues have left the lab ill-equipped to handle bird flu testing. Kisliuk had said the facility “maintained the supervision, staffing and resources necessary to provide timely and vital health and safety information to those asking us to perform tests.”

According to copies of email correspondence cited in the lawsuit, UC Davis in January denied the union’s request for records regarding short staffing or testing errors, calling the request “unduly burdensome.” It also denied its request for information about farms and other businesses that had samples tested at the lab, citing an exemption to protect from an “invasion of personal privacy.”

Workers at the lab had previously told The Times that they observed lapses in quality assurance procedures, as well as other mistakes in the testing process.

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Amy Fletcher, a UC Davis employee and president of the union’s Davis chapter, said the records would provide a necessary window into how staffing levels could be hurting farms and other businesses that rely on the lab for testing. Fletcher said workers have become afraid to speak about problems at the lab, having been warned by management that the some information related to testing is confidential.

The Davis lab is the only entity in the state with the authority to confirm bird flu cases.

The union, known as UPTE, represents about 20,000 researchers and other technical workers across the University of California system’s 10 campuses.

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Newsom's podcast sidekick: a single-use plastic water bottle

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Newsom's podcast sidekick: a single-use plastic water bottle

Johnny had Ed. Conan had Andy. And Gov. Gavin Newsom? A single-use plastic water bottle.

In most of the YouTube video recordings of Newsom’s new podcast, “This is Gavin Newsom,” a single-use plastic water bottle lurks on a table nearby.

Sometimes, it is accompanied by a single-use coffee cup. Other times, it stands alone.

Typically, such product placement would raise nary an eyebrow. But in recent weeks, environmentalists, waste advocates, lawmakers and others have been battling with the governor and his administration over a landmark single-use plastic law that Newsom signed in 2022, but which he has since worked to defang — reducing the number of packaged single-use products the law was designed to target and potentially opening the door for polluting forms of recycling.

Anti-plastic advocates say it’s an abrupt and disappointing pivot from the governor, who in June 2022, decried plastic pollution and the plague of single-use plastic on the environment.

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“It’s like that whole French Laundry thing all over again,” said one anti-plastic advocate, who didn’t want to be identified for fear of angering the governor. Newsom was infamously caught dining without a mask at the wine country restaurant during the COVID-19 lockdown.

Newsom’s efforts to scale back SB 54, the state’s single-use plastic recycling law, has dismayed environmentalists who have long considered Newsom one of their staunchest allies.

“Our kids deserve a future free of plastic waste and all its dangerous impacts … No more,” Newsom said in 2022, when he signed SB 54. “California won’t tolerate plastic waste that’s filling our waterways and making it harder to breathe. We’re holding polluters responsible and cutting plastics at the source.”

Asked about the presence of the plastic water bottle, Daniel Villaseñor, the governor’s deputy director of communications, had this response:

“Are you really writing a story this baseless or should we highlight this video for your editor?” Villaseñor said via email, attaching a video clip showing this reporter seated near a plastic water bottle at last year’s Los Angeles Times’ Climate Summit. (The bottles were placed near chairs for all the panelists; this particular one was never touched.)

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After this story was first published, the governor’s office said the plastic water bottles seen on the podcast were placed there by staff or production teams and not at Newsom’s request, and that the governor remains committed to seeing SB 54 implemented.

More than a half-dozen environmentalists and waste advocates asked to comment for this story declined to speak on the record, citing concerns including possible retribution from the governor’s office and appearing to look like scolds as negotiations over implementing SB 54 continue.

Dianna Cohen, the co-founder and chief executive of Plastic Pollution Coalition, said that while she wouldn’t comment on the governor and his plastic sidekick, she noted that plastic pollution is an “urgent global crisis” that requires strong policies and regulations.

“Individuals — especially those in the public eye — can help shift culture by modeling these solutions. We must all work to embrace the values we want to see and co-create a healthier world,” she said in a statement.

On Thursday, Newsom dropped a new episode of “This is Gavin Newsom” with independent journalist Aaron Parnas. In the video, there wasn’t a plastic bottle in sight.

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In Southern California, many are skipping healthcare out of fear of ICE operations

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In Southern California, many are skipping healthcare out of fear of ICE operations

Missed childhood vaccinations. Skipped blood sugar checks. Medications abandoned at the pharmacy.

These are among the healthcare disruptions providers have noticed since Immigration and Customs Enforcement operations began in Southern California earlier this month.

Across the region, once-busy parks, shops and businesses have emptied as undocumented residents and their families hole up at home in fear. As rumors of immigration arrests have swirled around clinics and hospitals, many patients are also opting to skip chronic-care management visits as well as routine childhood check-ups.

In response, local federally qualified health centers — institutions that receive federal funds and are required by law to provide primary care regardless of ability to pay — have been scrambling to organize virtual appointments, house calls and pharmacy deliveries to patients who no longer feel safe going out in public.

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“We’re just seeing a very frightening and chaotic environment that’s making it extremely difficult to provide for the healthcare needs of our patients,” said Jim Mangia, president of St. John’s Community Health, which offers medical, dental and mental health care to more than 100,000 low-income patients annually in Southern California.

Prior to the raids, the system’s network of clinics logged about a 9% no-show rate, Mangia said. In recent weeks, more than 30% of patients have canceled or failed to show. In response, the organization has launched a program called Healthcare Without Fear to provide virtual and home visits to patients concerned about the prospect of arrest.

“When we call patients back who missed their appointment and didn’t call in, overwhelmingly, they’re telling us they’re not coming out because of ICE,” said Mangia, who estimates that 25% of the clinic’s patient population is undocumented. “People are missing some pretty substantial healthcare appointments.”

A recent survey of patient no-shows at nonprofit health clinics across Los Angeles County found no universal trends across the 118 members of the Community Clinic Assn. of L.A. County, President Louise McCarthy said. Some clinics have seen a jump in missed appointments, while others have observed no change. The data do not indicate how many patients opted to convert scheduled in-person visits to telehealth so they wouldn’t have to leave home, she noted.

Patients have also expressed concerns that any usage of health services could make them targets. Earlier this month, the Associated Press reported that the U.S. Department of Health and Human Services shared the personal data of Medicaid enrollees with the U.S. Department of Homeland Security, including their immigration status. No specific enforcement actions have been directly linked to the data.

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“The level of uncertainty and anxiety that is happening now is beyond the pale,” McCarthy said, for patients and staff alike.

County-run L.A. General Medical Center issued a statement on Thursday refuting reports that federal authorities had carried out enforcement operations at the downtown trauma center. While no immigration-related arrests have been reported at county health facilities, “the mere threat of immigration enforcement near any medical facility undermines public trust and jeopardizes community health,” the department said in a statement.

Los Angeles County is among the providers working to extend in-home care options such as medication delivery and a nurse advice line for people reluctant to come in person.

“However, not all medical appointments or conditions can be addressed remotely,” a spokesperson said. “We urge anyone in need of care not to delay.”

Providers expressed concern that missing preventative care appointments could lead to emergencies that both threaten patients’ lives and further stress public resources. Preventative care “keeps our community at large healthy and benefits really everyone in Los Angeles,” said a staff member at a group of L.A. area clinics. He asked that his employer not be named for fear of drawing attention to their patient population.

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Neglecting care now, he said, “is going to cost everybody more money in the long run.”

A patient with hypertension who skips blood pressure monitoring appointments now may be more likely to be brought into an emergency room with a heart attack in the future, said Dr. Bukola Olusanya, a medical director at St. John’s.

“If [people] can’t get their medications, they can’t do follow-ups. That means a chronic condition that has been managed and well-controlled is just going to deteriorate,” she said. “We will see patients going to the ER more than they should be, rather than coming to primary care.”

Providers are already seeing that shift. When a health team visited one diabetic patient recently at home, they found her blood sugar levels sky-high, Mangia said. She told the team she’d consumed nothing but tortillas and coffee in the previous five days rather than risk a trip to the grocery store.

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