Science
Despite warnings from bird flu experts, it's business as usual in California dairy country
TIPTON, Calif. — It was a late fall morning and hundreds of cows — black and white splattered Holsteins and cappuccino-colored Jerseys — milled about a San Joaquin Valley dairy farm in the largest milk-producing state in the nation.
Nearby, workers herded some of the animals onto a rotating platform within the farm’s milking parlor and quickly attached pumping equipment. The machines buzzed and whirred as the cows were carried in a lazy arc to the parlor’s exit, where they were detached from milk hoses and sent on their way.
The scene seemed utterly unremarkable — except for the fact that five days earlier, the H5N1 bird flu virus that has ravaged California’s dairy herds for the last three months, had been confirmed on the farm. Although dozens of cows were sick, and their owner expected that number to climb, none of the farm’s workers wore personal protective equipment and vehicles from off site were let in and out with nary a hint of concern.
As H5N1 bird flu infects a growing number of California dairy farms, dead cows are becoming an increasingly common site in some areas of the Central Valley.
(Tomas Ovalle / For The Times)
The farm was just one of more than 400 California operations that have been confirmed to have suffered outbreaks of H5N1, but interviews with Central Valley dairy farmers, dairy workers and a recent study by the U.S. Centers for Disease Control and Prevention suggests the virus may be more widespread in people than the CDC’s official numbers suggest. Although authorities have been urging dairy farms and workers to take precautions against spreading infection, there is little evidence their cautions are being heeded.
No expert will say that H5N1 bird flu is going to become the next global pandemic, and government health officers say the virus poses a low risk to the public. However, some experts warn that nearly all the conditions needed for the virus to develop a threatening mutation are now present in many dairy farms: Lax testing protocols; close, unprotected contact between humans and animals; a general failure to take the threat seriously enough; and the approach of human flu season.
Since this particular clade of H5N1 virus (2.3.4.4b) first appeared in North America at the end of 2021, it has infected more than 600 dairy herds across 15 states, hundreds of millions of wild and domesticated birds, and at least 48 mammal species — such as dolphins, seals, cats and dogs.
“We are in a soup of virus. I mean, there’s virus everywhere around us at this point,” said Dr. Marcela Uhart, a wildlife veterinarian with UC Davis’ One Health institute, who is based in Argentina, speaking at symposium held by the O’Neill Institute at Georgetown Law recently. (11/15) “This virus is circulating left and right in mammals and in birds, as far as we can tell, some of them are not showing any signs of disease.”
In October, The Times visited Tipton, a dairy town in Tulare County, and spoke with several residents, including Elodia Ibañez, who said the number of reported human cases in California — which in mid-October was 16, and is now 23 — sounded too low. She said her husband, a dairy worker, told her that two of his co-workers had red, swollen eyes, but they had continued working despite displaying bird flu symptoms.
“It’s an illness that they know the cows have, and many cows have died. But the boss cared about the cows, not the workers,” Ibañez told The Times. “They never told them they have to go to the doctor to get a check-up.”
People often continue to work because they feel they have no other choice, she said. “Even though they say there are laws that protect them, there are still a lot of people who are fearful … They’re scared of losing their jobs.”
Anthony, also a Tipton resident, said he would talk, but did not want to share his last name; he has family members who work in dairies, and he feared impacting their employment by speaking out.
“My dad and uncle have told me there’s a bunch of dairies that have had outbreaks,” Anthony said. He said his dad and uncle take steps to stay safe, but many workers likely are not reporting getting sick because they don’t want to get in trouble.
“Some of them are here not legally. They’re relying on that job, they don’t want to jeopardize that,” he said.
In early November, the CDC published a study that looked for H5N1 antibodies in the blood of dairy workers in Michigan and Colorado. The agency sampled blood from 115 people; eight — or 7% — had antibodies. Only three dairy workers in those two states — one in Colorado, two in Michigan — have been positively identified as having the disease.
It’s this blindness to — and ignorance of — the virus’ reach that has infectious disease and health experts concerned.
And as human flu season approaches, and infected wild birds continue their southward migration down the North American flyways — stopping to rest in lakes, ponds, farms and backyards throughout the United States — experts worry conditions are becomingly increasingly ripe for a large “spillover” event.
If a virus — whether it’s a bird flu, a human influenza virus or a coronavirus — is given the opportunity to spread within and between organisms, the virus will evolve, adapt and mutate. Sometimes these mutations have little effect on its ability to transmit between organisms or cause severe disease. But sometimes, they do.
Then there’s the concern that the bird flu virus will find another flu virus that’s circulating — a human, swine or even other bird flu — and swap genetic material with it, potentially creating a new “super flu” that can spread easily between people, make its hosts very sick, or carry immunity to the antiviral medications used to treat infected patients.
In the 1970s, when the understanding of flu viruses was still being developed, Robert Webster, a researcher at St. Jude’s Hospital in Memphis, Tenn., conducted an experiment at the U.S. Department of Agriculture’s Plum Island Research Station, off the coast of Long Island.
He put a human flu virus — H3N2 — into one pig, and a swine flu virus — H1N1 — into another. He then put the two pigs in a pen with four other pigs. Seven days later, he and his team detected reassorted viruses — H3N1 and H1N2 — in one of the other pigs.
The viruses had swapped genes and created new combinations.
Jersey cows drink water at sunrise.
(Tomas Ovalle / For The Times)
The work of Webster and others led to the discovery that several of the nastier historical flu pandemics have been the result of this kind of reassortment. For instance, the 1918 flu outbreak — which killed approximately 50 million people worldwide — is believed to have been a recombined version of a bird and human flu.
It happened again in 2009, when a human and swine flu switched genes, unleashing the H1N1 swine flu outbreak that killed roughly 500,000 people.
Already there is evidence this virus is swapping genes. The birds currently traveling south from the Arctic are carrying a slightly different variant of H5N1 — called D1.1 or D1.2 — that has an altered take on the several of the flu’s viral segments.
It’s this strain that has put a Canadian teenager into critical condition at a British Columbia hospital. Health authorities don’t know where or how the child picked it up, except to note it wasn’t from cows or poultry. And they don’t know yet whether it has acquired the ability to move easily between people — although early and initial testing suggests it may have acquired some new and ominous traits, including changes that would make it easier to infect people.
Even so, as of this moment, there is no evidence that the H5N1 bird flu circulating among dairy cows and workers — known as B3.13 — has achieved the ability to move efficiently from human to human, or to cause severe illness. But with human flu season approaching — and the possibility that retail customers were drinking infected raw milk — the chances increase.
In an effort to spread awareness among dairy farms and potentially lure workers in for testing and decrease the chances for this virus to acquire mutations that could make it widespread and deadly in people, state health, agriculture and workers safety experts held a workshop at the Tulare Expo Center in late October, with help from the dairy trade group, Western United Dairies.
About 20 dairy workers and farmers sat through the two-hour session, which included English and Spanish presentations from the different state agenciess and dozens of slides
Dr. Erica Pan, California’s State Epidemiologist, told the audience her agency recommended personal protective equipment at work, and urged people to protect their eyes. She also told the audience to stay up to date on their recommended vaccines and refrain from consuming raw milk and undercooked beef, “especially ground beef.”
Eric Berg, Deputy Chief of Health and Research and Standards at CalOSHA said that farms under quarantine needed to establish restricted areas for infected animals. Workers, he said, should wear protective clothing, including coveralls, gloves and “and very important … eye protection and also respirators indoors.”
Eduardo Mondragon sat near the front of a conference room, nodding along as experts discussed safety protocols for dairy workers. As a manager of multiple dairy farms, Mondragon had watched the bird flu rip through the farms he oversaw in Tulare County and the cows he and his colleagues were tasked with caring for as they became sick.
Milk production fell as hundreds of cows became sick and about a dozen died, he said, but the dairy’s owner provided protective gear, including gloves and goggles, which workers were used to wearing daily.
At the dairy farm, Mondragon said they worked quickly when cows started getting sick over the summer to try and stop the spread. His boss sent him to the seminar in Tulare to learn more about the bird flu.
“For weeks, we never stopped,” he said, with many workers working weekend shifts to care for the cows. “We had a good handle on the flu, and because of that we didn’t suffer that many losses. Milk production yes, but animals, no.”
Mondragon knows that while his dairy farm saw the worst of the bird flu hit over the summer, none of the workers reported getting sick. He said friends in the industry in other countries were not yet affected like dairies in Tulare County.
After the seminar, Mondragon loaded up his white pickup truck with boxes of N95 masks, face shields and goggles to take back to his job site and share with the other workers.
Science
After rash of overdose deaths, L.A. banned sales of kratom. Some say they lost lifeline for pain and opioid withdrawal
Nearly four months ago, Los Angeles County banned the sale of kratom, as well as 7-OH, the synthetic version of the alkaloid that is its active ingredient. The idea was to put an end to what at the time seemed like a rash of overdose deaths related to the drug.
It’s too soon to tell whether kratom-related deaths have dissipated as a result — or, really, whether there was ever actually an epidemic to begin with. But many L.A. residents had become reliant on kratom as something of a panacea for debilitating pain and opioid withdrawal symptoms, and the new rules have made it harder for them to find what they say has been a lifesaving drug.
Robert Wallace started using kratom a few years ago for his knees. For decades he had been in pain, which he says stems from his days as a physical education teacher for the Glendale Unified School District between 1989 and 1998, when he and his students primarily exercised on asphalt.
In 2004, he had arthroscopic surgery on his right knee, followed by varicose vein surgery on both legs. Over the next couple of decades, he saw pain-management specialists regularly. But the primary outcome was a growing dependence on opioid-based painkillers. “I found myself seeking doctors who would prescribe it,” he said.
He leaned on opioids when he could get them and alcohol when he couldn’t, resulting in a strain on his marriage.
When Wallace was scheduled for his first knee replacement in 2021 (he had his other knee replaced a few years later), his brother recommended he take kratom for the post-surgery pain.
It seemed to work: Wallace said he takes a quarter of a teaspoon of powdered kratom twice a day, and it lets him take charge of managing his pain without prescription painkillers and eases harsh opiate-withdrawal symptoms.
He’s one of many Angelenos frustrated by recent efforts by the county health department to limit access to the drug. “Kratom has impacted my life in only positive ways,” Wallace told The Times.
For now, Wallace is still able to get his kratom powder, called Red Bali, by ordering from a company in Florida.
However, advocates say that the county crackdown on kratom could significantly affect the ability of many Angelenos to access what they say is an affordable, safer alternative to prescription painkillers.
Kratom comes from the leaves of a tree native to Southeast Asia called Mitragyna speciosa. It has been used for hundreds of years to treat chronic pain, coughing and diarrhea as well as to boost energy — in low doses, kratom appears to act as a stimulant, though in higher doses, it can have effects more like opioids.
Though advocates note that kratom has been used in the U.S. for more than 50 years for all sorts of health applications, there is limited research that suggests kratom could have therapeutic value, and there is no scientific consensus.
Then there’s 7-OH, or 7-Hydroxymitragynine, a synthetic alkaloid derived from kratom that has similar effects and has been on the U.S. market for only about three years. However, because of its ability to bind to opioid receptors in the body, it has a higher potential for abuse than kratom.
Public health officials and advocates are divided on kratom. Some say it should be heavily regulated — and 7-OH banned altogether — while others say both should be accessible, as long as there are age limitations and proper labeling, such as with alcohol or cannabis.
In the U.S., kratom and 7-OH can be found in all sorts of forms, including powder, capsules and liquids — though it depends on exactly where you are in the country. Though the Food and Drug Administration has recommended that 7-OH be included as a Schedule 1 controlled substance under the Controlled Substances Act, that hasn’t been made official. And the plant itself remains unscheduled on the federal level.
That has left states, counties and cities to decide how to regulate the substances.
California failed to approve an Assembly bill in 2024 that would have required kratom products to be registered with the state, have labeling and warnings, and be prohibited from being sold to anyone younger than 21.
It would also have banned products containing synthetic versions of kratom alkaloids. The state Legislature is now considering another bill that basically does the same without banning 7-OH — while also limiting the amount of synthetic alkaloids in kratom and 7-OH products sold in the state.
“Until kratom and its pharmacologically active key ingredients mitragynine and 7-OH are approved for use, they will remain classified as adulterants in drugs, dietary supplements and foods,” a California Department of Public Health spokesperson previously told The Times.
On Tuesday, California Gov. Gavin Newsom announced that the state’s efforts to crack down on kratom products has resulted in the removal of more than 3,300 kratom and 7-OH products from retail stores. According to a news release from the governor’s office, there has been a 95% compliance rate from businesses in removing the products.
(Los Angeles Times photo illustration; source photos by Getty Images)
Newsom has equated these actions to the state’s efforts in 2024 to quash the sale of hemp products containing cannabinoids such as THC. Under emergency state regulations two years ago, California banned these specific hemp products and agents with the state Department of Alcoholic Beverage Control seized thousands of products statewide.
Since the beginning of 2026, there have been no reported violations of the ban on sales of such products.
“We’ve shown with illegal hemp products that when the state sets clear expectations and partners with businesses, compliance follows,” Newsom said in a statement. “This effort builds on that model — education first, enforcement where necessary — to protect Californians.”
Despite the state’s actions, the Los Angeles County Board of Supervisors is still considering whether to regulate kratom, or ban it altogether.
The county Public Health Department’s decision to ban the sale of kratom didn’t come out of nowhere. As Maral Farsi, deputy director of the California Department of Public Health, noted during a Feb. 18 state Senate hearing, the agency “identified 362 kratom-related overdose deaths in California between 2019 and 2023, with a steady increase from 38 in 2019 up to 92 in 2023.”
However, some experts say those numbers aren’t as clear-cut as they seem.
For example, a Los Angeles Times investigation found that in a number of recent L.A. County deaths that were initially thought to be caused by kratom or 7-OH, there wasn’t enough evidence to say those drugs alone caused the deaths; it might be the case that the danger is in mixing them with other substances.
Meanwhile, the actual application of this new policy seems to be piecemeal at best.
The county Public Health Department told The Times it conducted 2,696 kratom-related inspections between Nov. 10 and Jan. 27, and found 352 locations selling kratom products. The health department said the majority stopped selling kratom after those inspections; there were nine locations that ignored the warnings, and in those cases, inspectors impounded their kratom products.
But the reality is that people who need kratom will buy it on the black market, drive far enough so they get to where it’s sold legally or, like Wallace, order it online from a different state.
For now, retailers who sell kratom products are simply carrying on until they’re investigated by county health inspectors.
Ari Agalopol, a decorated pianist and piano teacher, saw her performances and classes abruptly come to a halt in 2012 after a car accident resulted in severe spinal and knee injuries.
“I tried my best to do traditional acupuncture, physical therapy and hydrocortisone shots in my spine and everything,” she said. “Finally, after nothing was working, I relegated myself to being a pain-management patient.”
She was prescribed oxycodone, and while on the medication, battled depression, anhedonia and suicidal ideation. She felt as though she were in a fog when taking oxycodone, and when it ran out, ”the pain would rear its ugly head.” Agalopol struggled to get out of bed daily and could manage teaching only five students a week.
Then, looking for alternatives to opioids, she found a Reddit thread in which people were talking up the benefits of kratom.
“I was kind of hesitant at first because there’re so many horror stories about 7-OH, but then I researched and I realized that the natural plant is not the same as 7-OH,” she said.
She went to a local shop, Authentic Kratom in Woodland Hills, and spoke to a sales associate who helped her decide which of the 47 strains of kratom it sold would best suit her needs.
Agalopol currently takes a 75-milligram dose of mitragynine, the primary alkaloid in kratom, when necessary. It has enabled her to get back to where she was before her injury: teaching 40 students a week and performing every weekend.
Agalopol believes the county hasn’t done its homework on kratom. “They’re just taking these actions because of public pressure, and public pressure is happening because of ignorance,” she said.
During the course of reporting this story, Authentic Kratom has shut down its three locations; it’s unclear if the closures are temporary. The owner of the business declined to comment on the matter.
When she heard the news of the recent closures, Agalopol was seething. She told The Times she has enough capsules of kratom for now, but when she runs out, her option will have to be Tylenol and ibuprofen, “which will slowly kill my liver.”
“Prohibition is not a public health strategy,” said Jackie Subeck, executive director of 7-Hope Alliance, a nonprofit that promotes safe and responsible access to 7-OH for consumers, at the Feb. 18 Senate hearing. “[It’s] only going to make things worse, likely resulting in an entirely new health crisis for Californians.”
Science
There were 13 full-service public health clinics in L.A. County. Now there are 6
Because of budget cuts, the Los Angeles County Department of Public Health has ended clinical services at seven of its public health clinic sites.
As of Feb. 27, the county is no longer providing services such as vaccinations, sexually transmitted infection testing and treatment, or tuberculosis diagnosis and specialty TB care at the affected locations, according to county officials and a department fact sheet.
The sites losing clinical services are Antelope Valley in Lancaster; the Center for Community Health (Leavy) in San Pedro, Curtis R. Tucker in Inglewood, Hollywood-Wilshire, Pomona, Dr. Ruth Temple in South Los Angeles, and Torrance. Services will continue to be provided by the six remaining public health clinics, and through nearby community clinics.
The changes are the result of about $50 million in funding losses, according to official county statements.
“That pushed us to make the very difficult decision to end clinical services at seven of our sites,” said Dr. Anish Mahajan, chief deputy director of the L.A. County Department of Public Health.
Mahajan said the department selected clinics with relatively lower patient volumes. Over the last month, he said, the department has sent letters to patients about the changes, and referred them to unaffected county clinics, nearby federally qualified health centers or other community providers. According to Mahajan, for tuberculosis patients, particularly those requiring directly observed therapy, public health nurses will continue visiting patients.
Public health clinics form part of the county’s healthcare safety net, serving low-income residents and those with limited access to care. Officials said that about half of the patients the county currently sees across its clinics are uninsured.
Mahajan noted that the clinics were established decades ago, before the Affordable Care Act expanded Medi-Cal coverage and increased the number of federally qualified health centers. He said that as more residents gained access to primary care, utilization at some county-run clinics declined.
“Now that we have a more sophisticated safety net, people often have another place to go for their full range of care,” he said.
Still, the closures have unsettled providers who work closely with local vulnerable populations.
“I hate to see any services that serve our at-risk and homeless community shut down,” said Mark Hood, chief executive of Union Rescue Mission in downtown Los Angeles. “There’s so much need out there, so it always is going to create hardship for the people that actually need the help the most.”
Union Rescue Mission does not receive government funding for its healthcare services, Hood said. The mission’s clinics are open not only to shelter guests, up to 1,000 people nightly, but also to people living on the streets who walk in seeking care.
Its dental clinic alone sees nearly 9,000 patients a year, Hood said.
“We haven’t seen it yet, but I expect in the coming days and weeks we’ll see more people coming through our doors looking for help,” he said. “They’re going to have to find help somewhere.” Hood said women experiencing homelessness are especially vulnerable when preventive care, including sexual and reproductive health services, becomes harder to access.
County officials said staffing impacts so far have been managed through reassignment rather than layoffs. Roughly 200 to 300 positions across the department have been eliminated amid funding cuts, officials said, though many were vacant. About 120 employees whose positions were affected have been reassigned; according to Mahajan, no one has been laid off.
The clinic closures come amid broader fiscal uncertainty. Mahajan said that due to the Trump administration’s “Big Beautiful Bill,” Los Angeles County could lose $2.4 billion over the next several years. That funding, he said, supports clinics, hospitals and community clinic partners now absorbing patients who previously went to the clinics that closed on Feb. 27.
In response, the L.A. County Board of Supervisors has backed a proposed half-cent sales tax measure that would generate hundreds of millions of dollars annually for healthcare and public health services. Voters are expected to consider the measure in June.
Science
Mobile clinic brings mammograms to women on Skid Row
Sharon Horton stepped through the door of a sky-blue mobile clinic and onto a Skid Row sidewalk. She wore a yellow knit beanie, gold hoop earrings and the relieved grin of a woman who has finally checked a mammogram off her to-do list.
It had been years since her last breast cancer screening procedure. This one, which took place in City of Hope’s Cancer Prevention and Screening mobile clinic, was faster and easier. The staff was kind. The machine that X-rayed her breast was more comfortable than the cold hard contraption she remembered.
Relatively speaking, of course — it was still a mammogram.
“It’s like, OK, let me go already!” Horton, 68, said with a laugh.
The clinic was parked on South San Pedro Street in front of Union Rescue Mission, the nonprofit shelter where Horton resides. Within a week, City of Hope, a cancer research hospital, would share the results with Horton and Dr. Mary Marfisee, the mission’s family medical services director. If the mammogram detected anything of concern, they’d map out a treatment plan from there.
Naureen Sayani, 47, a resident of Union Rescue Mission, left, discusses her medical history with Adriana Galindo, a medical assistant, before getting a mammogram on last week.
(Kayla Bartkowski / Los Angeles Times)
“It’s very important to take care of your health, and you need to get involved in everything that you can to make your life a better life,” said Horton, who is looking forward to a forthcoming move into Section 8 housing.
Horton was one of the first patients of a new women’s health initiative from UCLA’s Homeless Healthcare Collaborative at Union Rescue Mission. Staffed by third-year UCLA Medical School students and led by Marfisee, a UCLA assistant clinical professor of family medicine, the clinic treats mission residents as well as unhoused people living in the surrounding neighborhood.
The new cancer screening project arrives at a time of dire financial pressures on county public health services.
Citing rising costs and a $50-million reduction in federal, state and local grant and contract income, the Los Angeles County Department of Public Health on Feb. 27 ended services at seven of 13 public clinics that provide vaccines, tests and treatment for sexually transmitted diseases and other services to housed and unhoused county residents.
Although Union Rescue Mission’s own funding comes mainly from private sources and is less imperiled by public cuts, the 135-year-old shelter expects the need for its services to rise, Chief Executive Mark Hood said.
Even as unsheltered homelessness declined for the last two years across Los Angeles County, the unsheltered population on Skid Row — long seen as the epicenter of the region’s homelessness crisis — grew 9% in 2024, the most recent year for which census data are available.
For many local women navigating daily concerns over housing, food and personal safety, “their own health is not a priority,” Marfisee said.
Those whose problems have become too serious to ignore face daunting obstacles to care. Marfisee recalled one patient who came to her with a lump in her breast and no identification.
In order to get a mammogram, Marfisee explained, the woman first needed to obtain a birth certificate, and then a state-issued identification card. Then she needed to enroll in Medi-Cal. After that, clinic staff helped her find a primary care physician who could order the imaging test.
Given the barriers to preventative care, homeless women die from breast cancer at nearly twice the rate of securely housed women, a 2019 study found. Marfisee’s own survey of the mission’s female residents found that nearly 90% were not up to date on recommended cancer screenings like mammograms and pap smears, which detect early cervical cancer.
To address this gap, Marfisee — a dogged patient advocate — reached out to City of Hope. The Duarte-based research and treatment center unveiled in March 2024 its first mobile cancer screening clinic, a moving van-sized clinic on wheels that it deploys to food banks and health centers, as well as to companies offering free mammograms as an employee benefit.
“In true Dr. Mary fashion, she saw the vision,” said Jessica Thies, the mobile screening program’s regional nursing director. After working through some logistical hurdles, the mission and City of Hope secured a date for the van’s first visit.
The next challenge was getting the word out to patients. Marfisee and her students walked through the surrounding neighborhood, went cot to cot in the women’s dorm and held two informational sessions in December and January to answer patients’ questions.
At the sessions, the team walked through the basics of who should get a mammogram (women age 40 or older, those with a family history of breast cancer) and the procedure itself. (“Like a tortilla maker?” one woman asked skeptically after hearing a description of the mammography unit.)
The medical students were able to dispel rumors some women had heard: The test doesn’t damage breast tissue, nor do the X-rays increase cancer risk. Others questioned a mammogram’s value: What good was it knowing they had cancer if they couldn’t get follow-up care?
On this latter point, Marfisee is determined not to let patients fall through the cracks.
Thirteen patients received mammograms at the van’s first visit on Wednesday. Within a week, City of Hope will contact patients with their results and send them to Marfisee and her team. She is already mentally mapping the next steps should any patient have a situation that requires a biopsy or further imaging: working with their case manager at the mission, calling in favors, wrangling with any insurance the patient might have.
“It’ll be a good fight,” Marfisee said, as residents in the adjacent cafeteria carried trays of sloppy joes and burgers to their lunch tables. “But we’ll just keep asking for help and get it done.”
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