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Deadly hantavirus outbreak strikes luxury cruise. What you should know about the disease

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Deadly hantavirus outbreak strikes luxury cruise. What you should know about the disease

A suspected outbreak of hantavirus, a rare but deadly disease that attacks the lungs, has left three people dead and several others severely ill aboard a luxury cruise ship.

Here’s what we know about the voyage and the virus that also made headlines last year after it killed Gene Hackman’s 65-year-old wife, Betsy Arakawa.

What’s going on?

Global health officials and the cruise operator, Oceanwide Expeditions, are investigating and working to contain the illnesses suspected to have been brought on by the rodent-borne illness aboard the MV Hondius — a Dutch-flagged ship, according to the World Health Organization.

On Monday, the WHO announced that the luxury ship carrying 147 passengers and crew had two laboratory-confirmed cases and five suspected cases of hantavirus. The three deaths are included in that total.

The cruise ship, which was on a 46-day journey that traveled from Antarctica with stops in Argentina, has remained off the coast of Cape Verde in the Atlantic Ocean. During a news conference, WHO officials said they’re planning to medically evacuate two individuals with suspected infections.

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The vessel departed Ushuaia, Argentina, on April 1 and traveled across the Atlantic with multiple stops in remote and ecological diverse regions, according to the WHO.

“The extent of passenger contact with local wildlife during the voyage, or prior to boarding in Ushuaia, remains undetermined,” the organization said in a statement.

What we know about hantavirus

Typically, hantavirus spreads by inhaling particles contaminated with the urine, feces or saliva of wild rodents.

“What we don’t know about this current outbreak is whether someone got onto the ship and was already sick or there were rodents on the cruise,” said Dr. Gaby Frank, director of the Johns Hopkins Special Pathogens Center.

There is, however, a strain of hantavirus that can be spread from human to human, known as the Andes virus, Frank said.

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In such a case, a person would first be infected by a wild rodent’s contaminated particles and then, after becoming infected themselves, pass the infection to another person.

There are 50 species of hantavirus. The virus that’s found in the Americas tends to cause a cardiopulmonary syndrome, a condition that affects the heart and the lungs, according to Frank.

There have been 890 laboratory-confirmed cases of hantavirus disease reported in the United States since surveillance began in 1993, according to the most recent data from the U.S. Centers for Disease Control and Prevention.

The data suggest that contracting hantavirus is rare, said Dr. Afif El-Hasan, member of the American Lung Assn.’s national board of directors.

“That being said, it’s probably underdiagnosed because the symptoms are a lot like the flu or other illness,” El-Hasan said. “And a lot of people may have passed away or had hantavirus, but it was never diagnosed.”

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There is no vaccine or specific antiviral medicine for hantavirius.

The ICU treatment may include intubation and oxygen therapy, fluid replacement and use of medications to lower blood pressure, according to the American Lung Assn.

Know the signs of hantavirus and next steps

Early symptoms of hantavirus are similar to the flu and include fatigue, fever and muscle aches, according to the CDC. Signs of these symptoms start to show within one to eight weeks after contact with an infected rodent.

Half of those who contract the virus also experience headaches, dizziness, chills, nausea, vomiting, diarrhea and abdominal pain.

Four to 10 days after the initial phase of the illness, another round of symptoms can develop, which include coughing, shortness of breath and possible tightness in the chest as the lungs fill with fluid.

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Even though contracting hantavirus in the United States continues to be a rare event, El-Hasan said, people should take these initial symptoms seriously and promptly seek medical care.

Hantavirus can be deadly. CDC officials said 38% of people who develop respiratory symptoms may die from the disease.

How to protect yourself

Hantavirus cases can occur year-round, but the peak seasons in the United States are in the spring and summer, which coincide with the reproductive seasons for deer mice.

To lessen your risk of infection, keep wild rodents out of your home, workplace, shed, cabin, car or other enclosed spaces.

Los Angeles County public health officials offer suggestions on how you can keep rodents at bay, which include:

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  • Sealing up holes, the width of a pencil or larger, that mice can squeeze into.
  • Place snap traps to catch any rodents. The CDC cautions against using glue or live traps because they can scare the rodents, causing them to urinate, which increases your chances of exposure to any virus they may be carrying.
  • Store all food items in rodent-proof containers.

If you find evidence of mice in a space that you frequent, local and state officials advise:

  • Before you clean, air out the space for 30 minutes. Equip yourself with rubber or plastic gloves, an N-95 mask and a disinfectant or mixture of bleach and water.
  • While cleaning, spray the contaminated areas with your disinfectant and let it soak for at least five minutes. Do not sweep or vacuum the area, the movement could stir up the infectious materials in the air. Instead, use paper towels, a sponge or a mop to clean. When you’re done, put everything, including cleaning materials, in a bag and toss it in your trash bin.
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Here’s why the Lincoln Memorial Reflecting Pool went green so fast

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Here’s why the Lincoln Memorial Reflecting Pool went green so fast

Just days after the Trump administration completed millions of dollars in renovations on the Lincoln Memorial Reflecting Pool to make it American flag-blue, residents and online users noted it had turned a phosphorescent green.

Here’s why:

The calm, still waters of the Reflecting Pool make it an ideal nursery for algae growth. Algae need nitrogen and phosphorus to grow, and the Reflecting Pool is primarily fed by the Potomac River, which gets heavy doses of those nutrients from nearby urban and agricultural lands.

The Potomac also absorbed one of the largest sewage spills in U.S. history earlier this year when a pipe burst five miles upstream of Washington, although that event probably happened too long ago to contribute to the algal bloom today.

Untreated sewage is high in nitrogen and phosphorus. When nutrient levels are high, feasting algae can quickly reproduce.

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The Department of the Interior said when the algae first appeared that it was “residual,” from the supply lines to the pool.

Experts also speculate that the darker blue color may be helping the Reflecting Pool absorb more heat. The higher temperatures promote algae growth by allowing their metabolisms to shift into overdrive.

Summer temperatures in D.C. aren’t helping. This week, temperatures are as high as 95 degrees in the city, prompting a heat alert.

The combination probably explains the excessive growth, turning the water surface an opaque green and preventing onlookers from seeing the new blue hue of the concrete basin.

Algae are important and beneficial organisms when the ecosystem is in balance. They’re the base of the aquatic food chain, fed on by herbivores of all shapes and sizes, including shrimp and juvenile fish, which in turn feed organisms higher up the food chain. The single-celled organisms use the power of the sun to produce energy through photosynthesis, similar to houseplants on your balcony.

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In an effort combat the algae in the Reflecting Pool, employees of the National Park Service were seen pouring in gallons of hydrogen peroxide, a chemical commonly used in pool maintenance.

The Department of the Interior also is employing a “high-tech nanobubble ozone technology” to destroy the cells of the algae.

Ozone — yes, the same irritant that is in smog — is a gas composed of three oxygen molecules, and the small size of the bubbles allow the most gas transfer into the water, where it can damage algal cells, similar to how it irritates our lungs.

This only treats the symptoms, however. Generally, ozone nanobubbling is effective as a temporary solution for algae blooms. Longer-term fixes would have to address what makes the Reflecting Pool so ideal for algae, such as its depth, darker color and inflow of nitrogen and phosphorus.

In California, ozone nanobubbles also have been used in a project to improve water quality in the Tijuana River. The 120-mile river that runs near the border in northern Mexico and Southern California was the site of a pilot study in 2025. The U.S. section of the International Boundary and Water Commission reported that the nanobubbling reduced “odors and bacteria,” but the project concluded prematurely after a flood swept some of the instrumentation into the river.

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This plant extract can make a lethal drug cocktail. Can it also treat opioid addiction?

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This plant extract can make a lethal drug cocktail. Can it also treat opioid addiction?

A plant extract that’s gaining popularity as a pain cure-all and has been associated with multiple California deaths in its concentrated, synthetic form has been approved for research as a treatment for opioid addiction by the federal government.

Kratom is derived from the leaves of Mitragyna speciosa, a tree native to Southeast Asia, and is commonly made into a powder or pill.

Researchers say people in the U.S. are using kratom to alleviate anxiety, treat chronic pain or as a remedy for the symptoms associated with quitting opioids, due to its ability to bind with opioid receptors in the body. But recently, public health officials have raised alarms about a component of the leaf called 7-hydroxymitragynine, also known as 7-OH, an alkaloid that has the potential for abuse and addiction in high doses.

Last year, the Los Angeles County Public Health Department linked the deaths of six county residents to the use of 7-OH mixed with other substances. The toxicology screens for some of the deceased revealed both kratom and 7-OH, leading to a countywide crackdown of products with either compound because they’re unregulated.

Although there is no scientific consensus on whether kratom has therapeutic value, the Food and Drug Administration has recommended that its potent 7-OH form be classified as a controlled substance. Consumers who use 7-OH as a pain reliever expecting an experience similar to consuming kratom are at risk, said Dr. Mason Turner, president-elect of the California Society of Addiction Medicine.

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“I have a couple of patients that I work with who use 7-OH for chronic pain management, not realizing the potential of the medication, and then developed an opioid use disorder,” Turner said. “I think in that case it was very clear they were seeking it for the chronic pain, not to get high, not to have some kind of experience, but really to reduce their pain.”

About two decades ago, Turner said, the healthcare industry started acknowledging the limits and risks of prescribing opioids for chronic pain. Some doctors pulled back on prescriptions, recognizing the potential for abuse.

That led some patients to find alternative solutions, he said.

“Maybe they don’t get a good benefit, or maybe the benefit from some of the other treatments is not as robust as what they got from opioids,” Turner said. “So they seek out some of these illicit products … or they look for kratom or 7-OH to be able to mitigate the pain.”

Turner said he supports further research into kratom and regulation because “it could be worth exploring as a treatment for chronic pain.”

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On June 1, the National Institutes of Health announced that researchers from the University of Florida would begin the first phase of clinical trials on kratom to evaluate it as a potential treatment for opioid addiction. The research would be done with the FDA’s approval, according to officials.

“This … is a major step toward expanding treatment options for the millions of Americans struggling with opioid use disorder, which has contributed to historically high overdose mortality rates,” said Dr. Nora Volkow, director of NIH’s National Institute on Drug Abuse, in a statement.

Interest in kratom surged in the last couple of years as users have reported consuming the compound in the form of a pill, powder or tea to treat various ailments. A John Hopkins survey conducted in 2020 reported that 91% of respondents used kratom to treat chronic pain, 67% to treat anxiety, 64% for depression and 41% to treat opioid dependence.

A more recent study by the University of Michigan and Texas State University found that more than 5 million people in the U.S., including more than 100,000 children ages 12 to 17, have used kratom, the compound experts say is growing in popularity with young adults.

In the study, which analyzed data from the National Survey on Drug Use and Health collected between 2021 and 2024, researchers say that despite numerous state-level bans on kratom across the nation, its use is at an all-time high and is increasing.

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People between the ages of 21 and 34 said they used kratom at least once and 1% said they used it in the last year. The share of children ages 12 and older who said they had used kratom increased from 1.6% in 2021 to 1.9% in 2024.

The FDA has stated that neither kratom nor 7-OH are approved as drug products, dietary supplements or food additives, but that hasn’t stopped storefronts and companies from selling them as such.

Up until November you could find kratom and 7-OH products in smoke shops and specialty stores in California, but that has stopped.

“Until kratom and its pharmacologically active key ingredients mitragynine and 7-OH are approved for use, they will remain classified as adulterants in drugs, dietary supplements and foods,” the California Department of Public Health told The Times via email.

Kratom “Feel Free Classic” liquid products are displayed at a smoke shop in Los Angeles in 2024 before they were banned.

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(Michael Blackshire / Los Angeles Times)

In May, the California Department of Public Health and Atty. Gen. Rob Bonta filed a complaint against Ashlynn Marketing Group Inc., accusing the company of repeatedly flouting the state’s regulations on kratom products.

The filing, submitted in the San Diego County Superior Court, seeks a judge’s order to condemn and destroy the embargoed kratom products, halt ongoing unlawful manufacturing and impose civil penalties.

The California Department of Public Health “is pursuing legal action because Ashlynn’s continued manufacture and sale of these products pose a clear and preventable public‑health risk and violates state and federal law,” said Dr. Erica Pan, the department’s director and state public health officer. “7-OH and kratom-derived products have been associated with addiction, serious health harms, overdose and death.”

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The state is alleging its inspectors visited Ashlynn Marketing Group’s facility in Santee in May 2025 and found kratom powders, capsules, liquids and chewable tablets being manufactured and held for sale.

During the visit, inspectors issued an embargo to prohibit the sale and distribution of all kratom-related materials on-site, according to the complaint.

Public health inspectors conducted follow-up visits at the facility in October and April, “collecting evidence at both inspections that indicated embargoed kratom products had been moved, tampered with and repackaged,” according to public health officials.

“In addition, investigators observed evidence of continued manufacturing and distribution of kratom materials,” officials said. “The firm’s owner continues to manufacture kratom products and ships orders weekly.”

To date, the California Department of Public Health has seized more than $5 million worth of kratom and 7-OH products, a spokesperson for the department told The Times.

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California and Los Angeles County are considering whether to tighten regulations or ban the compounds altogether.

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Scientists find a whale graveyard in the Indian Ocean that’s millions of years old

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Scientists find a whale graveyard in the Indian Ocean that’s millions of years old

Scientists have unearthed communities of marine life — including jellyfish, tubeworms and brittle stars — thriving on a whale graveyard that is millions of years old.

These graveyards form when whale carcasses fall to the sea floor, becoming a sustaining snack for nearby critters. This one, located up to 23,000 feet below the surface of the southeastern Indian Ocean, spans the largest area and is so far the deepest and oldest found.

A whale’s sheer size and the unique chemistry of its bones are the keys to forming these unique underwater neighborhoods, said Xikun Song, a biologist with the Chinese Academy of Sciences’ Institute of Deep-sea Science and Engineering.

“At the same time, the very nature of the deep ocean makes these sites exceptionally difficult for scientists to locate,” Song, who was involved with the latest find, wrote in an email.

Researchers explored the remains during multiple deep-sea submersible trips in 2023, collecting samples and mapping the extent of the necropolis. They found five carcass sites and fossils, including skulls belonging to beaked and baleen whales. The oldest bones date back 5.3 million years.

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Feeding and living on the carcasses were myriad creatures, large and small, including sea cucumbers, squat lobsters and saltwater clams. Many of them are likely species that have never been documented, according to findings published Wednesday in the journal Nature.

“The potential number of specimens is just astounding,” said paleontologist Stephen Godfrey with the Calvert Marine Museum in Maryland, who wasn’t involved in the research.

Many factors likely conspired to preserve the bones for millions of years, according to the study authors. They’re dense enough to outlast attacks from bone-eating worms, and located deep enough in the ocean to avoid getting buried by dust and loose particles. The bones also were coated with a light layer of minerals from the surrounding seawater, which may have prevented them from degrading.

Why did so many whales die here? Maybe they were already living in the area and died of natural causes. A few could have perished from exhaustion or illness caused by deep-sea diving. The area’s shape, akin to the letter V, could also have funneled the remains to their resting spot, the authors wrote.

Such discoveries are important because they clue scientists into the vibrant communities that find a way to live even in remote, hard-to-reach environments.

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Studying the whale graveyards “is important for understanding how life can adapt to such extreme conditions, not only due to the lack of light and oxygen but also to the incredibly high pressure,” said study co-author and paleontologist Giovanni Bianucci with the University of Pisa in Italy in an email.

Ramakrishnan writes for The Associated Press.

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education and the Robert Wood Johnson Foundation.

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