Science
Contributor: Save the Earth's 'creepy-crawlies.' Some of them just might save us
When I was a child, I visited the village in India where my father grew up. As we strolled down dirt roads, he reminisced on his barefoot youth. I don’t remember much of what he said — I was too busy looking for reptiles in the shrubs. Later that day, we came upon a gaggle of children surrounding a snake. For a split moment, I felt like the luckiest kid in the world, elated to stumble upon my favorite animal in the wild. But the other kids didn’t share my joy. Instead, one of them beat it to death with a stick while the others celebrated. I broke down into tears.
Three decades later, I’m willing to forgive them. Each year, snakes kill 60,000 people across South Asia, and many more around the world. It’s entirely reasonable, even natural, to fear reptiles, but that fear has curdled into something nefarious. Eradication campaigns, combined with the pressures of habitat loss and climate change, have pushed global reptile populations to the brink; 1 in 5 reptile species now face imminent extinction. This is a moral, ecological and medical calamity. Reptiles and other frightful creatures have saved untold lives, and it would be a huge mistake to hasten their demise.
The world’s “creepy-crawlies” are responsible for some of the most consequential pharmaceutical breakthroughs of the past century. ACE inhibitors, a first-line treatment for high blood pressure, were derived from the venom of the yarara, a 5-foot-long pit viper native to South America. In the ’60s, researchers noticed that workers on local banana plantations would faint when bitten by the snake, a sign of rapid-onset hypotension. By 1981, researchers had isolated the pressure-dropping compound from its venom, created a synthetic formulation, and won regulatory approval for captopril, which became the pharmaceutical company Squibb’s first billion-dollar drug. As an internal medicine doctor, I have administered this exact medicine to countless patients; worldwide, 20 million people rely on this class of drugs, known as ACE inhibitors, to avoid heart attacks and chronic kidney disease. They are a medical miracle.
Federal funding for obscure reptile research can pay big dividends. In the 1990s, the United States Department of Veterans Affairs financed a study of gila monsters, hoping to understand how these venomous lizards go for long periods without food but maintain stable blood sugar levels. The investigation led to a remarkable discovery: Gila monster venom contains a peptide that stimulates insulin production. That’s how scientists eventually synthesized GLP-1 agonists like semaglutide (which are sold under the brand names Ozempic and Wegovy), which have revolutionized diabetes management and weight loss, while demonstrating other positive clinical effects across the body.
The modern pharmaceutical industry has long been powered by nature, and there’s no signs of this changing — even as artificial intelligence transforms drug development. One-third of all small-molecule drugs approved by the Food and Drug Administration from 1981 to 2014 were derived from naturally occurring compounds, forged by the great furnace of evolution. Recombinant hirudins, for example, are a class of medicines used to treat patients with allergies to traditional anti-clotting drugs; they originated in the salivary glands of blood-sucking leeches. Snails may hold the secret to new painkillers that don’t possess the addictive qualities of opiates. Enzymes derived from deep-sea bacteria have been used to make tests for COVID-19. The most undervalued creatures often hold the most miraculous secrets, but we won’t untangle those mysteries without protecting neglected species, preserving research funding and partnering with the communities who live closest to nature.
We can’t study animals if there are no animals left to study. The planet is in the midst of a mass extinction event, precipitated by human actions. In the last 50 years, nearly 75% of wildlife populations have declined. To save what’s left of nature, governments must follow through on their 2022 commitment to conserve 30% of the world’s land and sea by 2030, an initiative known as “30×30.”
The U.S. government must also reverse its short-sighted policies that are cutting research funds. Scientific inquiry, no matter how strange-sounding or unfamiliar, is rarely “wasteful” or “frivolous.” Federal funding for big, out-there ideas has led to breakthrough discoveries like mRNA vaccines. Often, the most transformational research begins with an unusual grant proposal, probably deemed too risky for private funding. When scientists are empowered to follow their curiosity, everyone benefits — but somebody has to be willing to take a chance on them. If we stop investing in medical research today, we forgo the life-saving discoveries of tomorrow.
Scientists, for their part, must open themselves up to new partnerships and perspectives. In remote corners of the world, communities possess tremendous knowledge of local flora and fauna, but few medical researchers from academia or the healthcare industry have ever bothered to ask them about it. Many of these communities are reasonably skeptical of outside researchers, who have been known to patent traditional remedies without compensating the original source of knowledge, a practice known as “biopiracy.” It’s long past time to bridge that gap — between science and tradition, Global North and Global South — and cooperate in a mutually beneficial way.
We all have something to learn from these communities, not just about healing, but about coexistence. This Earth Day, may we all resolve to admire the exquisite variety of life on this planet; meet the strange and fearsome with curiosity rather than revulsion; and remember that we are one small part of nature, rather than masters of it. All living things on this planet are connected, our fates all intertwined. Saving the world’s reptiles isn’t merely an act of altruism — it’s an act of self-preservation.
Neil M. Vora is a practicing physician, a senior advisor at Conservation International and the executive director of the Preventing Pandemics at the Source Coalition.
Science
Why new dads shouldn’t panic about low testosterone
Three months after his son was born, Kevin Maguire felt alone.
It was 2019. He had recently moved to Barcelona with his wife and daughter and was working on marketing projects for Fortune 500 companies. The birth of his son, Bodhi, should have been a joyous event. But Maguire, now 43, became sad and irritable, and didn’t want to be around his newborn. He withdrew from family and friends, often playing video games late into the night or finding excuses to get out of the house.
“I would take the dog out for a walk,” Maguire said. “I wanted to get far away enough that I wouldn’t bump into anyone I knew and I would just sit and cry.”
Desperate for answers, he entered his symptoms online. Maguire, author of the recently published book “The New Fatherhood: Why Everything They Told You About Being a Dad Is Wrong, and How Embracing It Will Transform Your Life,” knew to look for signs of the “baby blues” in his wife. But he was surprised by articles that said men could experience postpartum depression too. The diagnosis resonated and he began writing about his condition and the trials of fatherhood on Substack.
New dads face psychological pressures, from sleepless nights to sky-high bills, which can contribute to postpartum depression. So can shifting hormone levels.
“One thing I found in my lab’s research is that when new dads have really low levels of testosterone, they might report more symptoms of postpartum depression,” said Darby Saxbe, a professor of psychology at USC and author of the recently published “Dad Brain: The New Science of Fatherhood and How It Shapes Men’s Lives.”
While hormonal shifts can create challenges, they also help men adapt to fatherhood, Saxbe explained. Several hormones can spike in men when they become dads, including oxytocin, linked to better relationship quality; vasopressin, associated with emotional bonding; and prolactin, which promotes lactation in women and caregiving behavior in guys.
New dads can also experience a decline in testosterone. According to a 2011 paper from University of Notre Dame professor Lee Gettler, part of the largest study on fatherhood and testosterone ever conducted, men averaged around a 25% drop in testosterone after becoming fathers.
While dads have reasons to be concerned by plummeting levels of testosterone, a modest dip isn’t necessarily a disaster — in fact, it can make men better parents and partners.
“We often get invested in the idea that men should always have the highest possible levels of testosterone,” Saxbe said. “What the research tells us is a little more nuanced. You really want flexibility. You want a hormonal system that can adapt to the different demands of your life.”
The prospect of a decline might scare soon-to-be fathers, especially those on TikTok and Instagram, where accounts push the idea that having “high T” is the key to being a “real man,” according to a recent study in the journal Social Science & Medicine.
Influencers stand to profit persuading men there’s a widespread “masculinity crisis,” the researchers found, noting that 72% of the accounts they analyzed had a stake in testosterone supplements and treatments.
But studies show more testosterone isn’t always better. “We found that when dads have higher testosterone, even before birth, they’re less invested [than men with lower testosterone] in co-parenting a few months after birth,” Saxbe said. High T fathers were more stressed from parenting than their lower T counterparts, and had partners who were less satisfied in their romantic relationships.
This jibes with the challenge hypothesis, which says, in multiple species, testosterone levels rise when males battle for attention from potential mates and go down when it’s time to take care of the young.
While a small decline can be adaptive, dads face mental health risks when their testosterone drops too low.
There is no “normal” level of testosterone, said Dr. Jesse Mills, director of the Men’s Clinic at UCLA Health. Experts recommend that men should consider treatment if their levels dip below 300 nanograms per deciliter (ng/dL). But men metabolize testosterone in different ways, meaning a healthy level for one might be low for another.
“If a new dad comes to me and his testosterone is 298 [ng/dL], he’s below the threshold,” Mills said. “But if he has zero symptoms and everything else is going great — he’s over the moon with his new child, he’s so happy — that’s not somebody I’m going to treat with testosterone.”
He notes that the drop in testosterone fathers experience can partly be attributed to the stresses that come with a new kid: less sleep, a poor diet and fewer trips to the gym. That means there are precautions that expectant fathers can take that don’t involve testosterone replacement therapy (TRT).
Still, while some guys with low testosterone levels might not need TRT, others in the “normal” range could benefit from treatment. (Dads who want another kid soon, beware. Mills notes that testosterone replacement therapy can take a man’s sperm count to zero.)
Both Mills and Saxbe stress that men should be paying attention to symptoms of low testosterone — such as depression and low libido — rather than trying to reach or maintain an ideal number. They also agree that tending to mental health concerns is hugely important for new fathers.
Eventually, after Maguire researched his condition, he recovered after time spent meditating, exercising and bonding with his son.
“A lot of new dads don’t realize how much they’re struggling because they feel ashamed or because they don’t realize it’s common shortly after the birth of a baby,” Saxbe said.
When they struggle, fathers can fixate on testosterone because that’s what modern culture tells them will make them feel better. And sometimes testosterone replacement therapy works. But Saxbe stresses a lot of men could use psychotherapy or support groups that bring dads together, as well as more time bonding with loved ones in general.
“The thing that predicts a man’s well-being and longevity is the quality of his relationships with other people,” said Saxbe. “You can be the world’s best weightlifter. You can have a low body-fat percentage. You can be killing it at work. Those things don’t predict how happy you’re going to be at 80.”
Science
Video: NASA Announces Artemis III Crew
new video loaded: NASA Announces Artemis III Crew
transcript
transcript
NASA Announces Artemis III Crew
NASA announced the crew of Artemis III mission, which will fly to low-Earth orbit to test rendezvous and docking maneuvers with one or two lunar landers.
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“I am excited to welcome you as the next crew in the Artemis journey to successfully return to the moon — this time to stay.” “I’m honored by the role that I’ve been given. I’m also very humbled by the task in front of us. But first and foremost, I’m grateful.” “So with that, the Artemis II crew, comrade, hands you the baton. You got the controls.” “As you know, we had a significant anomaly at our Launch Complex 36A on May 28. We’ve redoubled our efforts and are moving forward.”
By Alisa Shodiyev Kaff
June 9, 2026
Science
Santa Monica Mountains’ last steelhead trout survived the Palisades fire — and even had babies
Scientists feared the Santa Monica Mountains’ last remaining steelhead trout were dead, smothered by debris flows unleashed by the Palisades fire.
But the endangered fish surprised them: A team of biologists recently spotted 30 of the rare trout — and 21 babies — in Topanga Creek.
“There was a lot of happy dancing in the creek,” said Rosi Dagit, principal conservation biologist for the Resource Conservation District of the Santa Monica Mountains, which works with public and private landowners to conserve natural resources.
That’s because the steelhead here are endangered, at both the state and federal levels. Once, they swam in most streams of the Santa Monicas, but their numbers plummeted amid overfishing and coastal development. Increasingly frequent wildfire has further stressed their habitat. Topanga Creek, a biodiversity hot spot, is home to their last known population in the mountains that stretch from the Hollywood Hills to Point Mugu in Ventura County.
The trout that were spotted, including this one, are part of a distinct Southern California population that’s listed as endangered at the state and federal levels.
(RCDSMM Stream Team)
The California Department of Fish and Wildlife spearheaded a complex mission to rescue trout threatened by the Palisades fire that sparked in January 2025.
Time was of the essence. The fire hadn’t yet been fully contained. But rain was on the way, which would sweep massive amounts of sediment from the denuded hillsides into the water. Fish are often killed this way.
Crews stunned the fish with electricity, scooped them up in buckets, trucked them to a hatchery and ultimately moved them to Arroyo Hondo Creek in Santa Barbara County.
Within days, Topanga Creek was choked with mud. Some assumed the fish left behind were goners.
But in March, the conservation district’s team found four. The following month, when water conditions were clearer, they saw more.
“These fish continue to amaze me,” said Kyle Evans, environmental program manager for the state Department of Fish and Wildlife, who had seen the damage to the creek. “I had seen populations get wiped out in similar situations. So when I heard, I was thrilled.”
Evans surmises the fish that survived were in an area of the creek where less charred material and sediment were swept in.
“These fish likely hunkered down, were hiding under some rocks or places to try to get away from the main concentration of flow,” he said. “And luckily they weren’t buried.”
The ones that were spotted were fairly small, around 6 to 14 inches. Rainbow trout and steelhead trout are the same species, but with different lifestyles. If the fish remain in freshwater, they’ll be considered rainbows. However, they can migrate to the ocean and become steelhead, where they typically grow larger before returning to their natal waters to spawn.
Topanga Creek hasn’t fully recovered from the damage it sustained, but scientists say it’s looking better. Surveys last year were “so depressing,” Dagit said, with very few animals, and stretches that were essentially transformed into flat roads from all the sediment buildup. Some of the riparian canopy burned right down to the creek.
Then came 32 inches of rain over the last nine months, scouring out and moving sediment, creating deeper pools. Dagit said they recently found newt egg masses for the first time in years, as well as a few adult newts and many frogs. Plants that provide cover are starting to recover.
She provided photos comparing certain pools last year and this year, some dramatically transformed. In September 2025, the Shrine Pool could have been an overgrown hiking trail. This April, it was filled with shallow water.
The Shrine Pool in September 2025, left, and the same location in April 2026, right, with RCDSMM’s Isaac Yelchin donning a wetsuit.
(RCDSMM Stream Team)
Topanga Creek is home to another endangered fish, the small but hardy northern tidewater goby, often described as cute. Not long before the trout operation, Dagit led a rescue of hundreds of these fish too. Many were repatriated to the lagoon at the mouth of the creek in a moving ceremony last June.
There’s still the matter of what to do with the trout that were moved to Santa Barbara County last year. Evans would like to bring them home to the Santa Monicas at some point, but isn’t sure if it will happen. On one hand, they could bolster the small, genetically isolated surviving population. On the other, they might inadvertently bring in a disease or bacteria. There is some time to decide. Evans estimates the creek still needs to recover for two to three more years.
For now, the fish are functioning fine in their adopted creek. Experts worried the trauma wrought by the move would disrupt their spawning process, but they had babies that spring. This year, they spawned again.
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