Science
As global plastic production grows, so does the concentration of microplastics in our brains
Finding microplastics in human body parts is not new: Scientists have uncovered the minuscule waste products in human blood, lungs, brains, hearts and testicles.
But a new study, published Monday in the journal Nature Medicine, shows a lockstep relationship between the amount of plastic found in tissues harvested from human cadavers and the amount being produced by the plastic industry.
As global plastic production has ramped up in the last 20 years, so too has the concentration of these shredded, fossil fuel-derived polymers in human tissue samples.
The findings are “pretty striking,” said Phil Landrigan, director of the Program for Global Public Health and the Common Good at Boston College, who was not affiliated with the research.
The study also showed a concerning correlation between patients who had received a dementia diagnosis before they died and the amount of plastic particles found in their brains — adding to a growing body of research indicating that the presence of these particles in the human body can potentially cause harm.
The study was published by a team of researchers at the University of New Mexico, Oklahoma State University, Duke University and Universidad del Valle, in Colombia.
The team acquired brain, liver and kidney tissue samples from patients who had undergone autopsies between 2016 and 2024 at the University of New Mexico.
To determine both the concentration and kinds of plastic in the samples, the team visually inspected the samples and applied pyrolysis-gas chromatography–mass spectrometry — a technique that allowed them to analyze the tissue’s chemical composition.
They found that the concentrations of particles in kidney and liver samples were comparable, with an average of 433 micrograms of microplastic per gram of tissue in the liver samples and 404 micrograms per gram of the kidney samples.
But the levels seen in the brain samples — all taken from the frontal lobe — dwarfed those numbers, and showed a jump over time. In the samples they harvested from people who died in 2016, they found average concentrations of 3,345 micrograms/gram. In the 2024 cohort, the average was 4,917.
“I never would have imagined it was this high,” said Matthew Campen, professor of pharmaceutical sciences at the University of New Mexico. “I certainly don’t feel comfortable with this much plastic in my brain, and I don’t need to wait around 30 more years to find out what happens if the concentrations quadruple.”
The concentrations of microplastics the researchers found were independent of the biological age of the deceased person — it didn’t matter if the person was young or old when they died. What mattered was the year they died — the more recent the death, the more accumulated plastic in the body.
Intrigued by this increase in plastic concentration over time, the researchers obtained more brain tissue samples. This time, they examined brains from people who died between 1997 and 2013. They made sure the cadavers were similarly aged to the ones they had already examined — but could not control for geography. The second cohort all came from people who had died on the East Coast.
Again, the researchers found “significantly increasing trends for total plastics” over time in this second group of samples.
Polyethylene — a plastic polymer used to make things such as plastic bags, milk jugs, shampoo bottles, etc. — was the most common microplastic found in the brain. It comprised 75% of the plastic shards observed in the brain tissue samples. But the researchers also detected polypropylene (the plastic used to make yogurt cups and rigid takeout food containers), polyvinylchloride (which is used in most water pipes), and styrene-butadiene rubber (found in some pneumatic tires, shoe soles, brake pads and electrical insulation).
The concentration of all of these plastics increased from 2016 to 2024, irrespective of the biological age of the cadaver.
They also noted that brain tissue harvested from patients who’d been diagnosed with dementia had higher concentrations of microplastics than those who hadn’t. Although it was a concerning observation, they noted that their sample size was small, and that hallmarks of dementia include brain tissue atrophy, impaired blood-brain barrier integrity, and poor brain clearance mechanisms — which could themselves lead to microplastic buildup.
Therefore, they could make no claims to causation — just correlation.
Landrigan said the work reinforces our knowledge “that we’re all exposed, that these things actually get into our bodies, into people of all ages” and that it “appears to be getting worse with time.”
He said it adds to the urgency of a Global Plastics Treaty — to cap plastic production — and which reached an impasse at the last round of negotiations in South Korea, in 2024. He said negotiators plan to reconvene later this year.
According to Landrigan, it’s unclear how the United States, under President Trump, would approach the treaty. If Trump follows the advice of the fossil fuel proponents in his administration, it’s likely the U.S. will vote the deal down — or not even show up.
But if the Robert F. Kennedy Jr. element gets a seat at the table, the U.S. is a wild card, Landrigan said. Kennedy was openly critical of the Biden administration for not doing enough to stanch the flow of microplastics into the environment, and he penned a detailed plan that would ban most hazardous chemicals, reform the recycling infrastructure and curtail the production of plastics.
Landrigan said he has known Kennedy for decades, and would happily sit down with him to present this research and the growing number of studies showing the harms these particles — and the chemicals they carry — cause in the human body.
“I’m a pediatrician with the American Academy of Pediatrics, and we’ve always taken the position that the academy will do what it has to do to protect children’s health. We will always stand up for children. So, if there’s an opening there for conversation with Bobby, why not?” he said.
Science
Why new dads shouldn’t panic about low testosterone
Three months after his son was born, Kevin Maguire felt alone.
It was 2019. He had recently moved to Barcelona with his wife and daughter and was working on marketing projects for Fortune 500 companies. The birth of his son, Bodhi, should have been a joyous event. But Maguire, now 43, became sad and irritable, and didn’t want to be around his newborn. He withdrew from family and friends, often playing video games late into the night or finding excuses to get out of the house.
“I would take the dog out for a walk,” Maguire said. “I wanted to get far away enough that I wouldn’t bump into anyone I knew and I would just sit and cry.”
Desperate for answers, he entered his symptoms online. Maguire, author of the recently published book “The New Fatherhood: Why Everything They Told You About Being a Dad Is Wrong, and How Embracing It Will Transform Your Life,” knew to look for signs of the “baby blues” in his wife. But he was surprised by articles that said men could experience postpartum depression too. The diagnosis resonated and he began writing about his condition and the trials of fatherhood on Substack.
New dads face psychological pressures, from sleepless nights to sky-high bills, which can contribute to postpartum depression. So can shifting hormone levels.
“One thing I found in my lab’s research is that when new dads have really low levels of testosterone, they might report more symptoms of postpartum depression,” said Darby Saxbe, a professor of psychology at USC and author of the recently published “Dad Brain: The New Science of Fatherhood and How It Shapes Men’s Lives.”
While hormonal shifts can create challenges, they also help men adapt to fatherhood, Saxbe explained. Several hormones can spike in men when they become dads, including oxytocin, linked to better relationship quality; vasopressin, associated with emotional bonding; and prolactin, which promotes lactation in women and caregiving behavior in guys.
New dads can also experience a decline in testosterone. According to a 2011 paper from University of Notre Dame professor Lee Gettler, part of the largest study on fatherhood and testosterone ever conducted, men averaged around a 25% drop in testosterone after becoming fathers.
While dads have reasons to be concerned by plummeting levels of testosterone, a modest dip isn’t necessarily a disaster — in fact, it can make men better parents and partners.
“We often get invested in the idea that men should always have the highest possible levels of testosterone,” Saxbe said. “What the research tells us is a little more nuanced. You really want flexibility. You want a hormonal system that can adapt to the different demands of your life.”
The prospect of a decline might scare soon-to-be fathers, especially those on TikTok and Instagram, where accounts push the idea that having “high T” is the key to being a “real man,” according to a recent study in the journal Social Science & Medicine.
Influencers stand to profit persuading men there’s a widespread “masculinity crisis,” the researchers found, noting that 72% of the accounts they analyzed had a stake in testosterone supplements and treatments.
But studies show more testosterone isn’t always better. “We found that when dads have higher testosterone, even before birth, they’re less invested [than men with lower testosterone] in co-parenting a few months after birth,” Saxbe said. High T fathers were more stressed from parenting than their lower T counterparts, and had partners who were less satisfied in their romantic relationships.
This jibes with the challenge hypothesis, which says, in multiple species, testosterone levels rise when males battle for attention from potential mates and go down when it’s time to take care of the young.
While a small decline can be adaptive, dads face mental health risks when their testosterone drops too low.
There is no “normal” level of testosterone, said Dr. Jesse Mills, director of the Men’s Clinic at UCLA Health. Experts recommend that men should consider treatment if their levels dip below 300 nanograms per deciliter (ng/dL). But men metabolize testosterone in different ways, meaning a healthy level for one might be low for another.
“If a new dad comes to me and his testosterone is 298 [ng/dL], he’s below the threshold,” Mills said. “But if he has zero symptoms and everything else is going great — he’s over the moon with his new child, he’s so happy — that’s not somebody I’m going to treat with testosterone.”
He notes that the drop in testosterone fathers experience can partly be attributed to the stresses that come with a new kid: less sleep, a poor diet and fewer trips to the gym. That means there are precautions that expectant fathers can take that don’t involve testosterone replacement therapy (TRT).
Still, while some guys with low testosterone levels might not need TRT, others in the “normal” range could benefit from treatment. (Dads who want another kid soon, beware. Mills notes that testosterone replacement therapy can take a man’s sperm count to zero.)
Both Mills and Saxbe stress that men should be paying attention to symptoms of low testosterone — such as depression and low libido — rather than trying to reach or maintain an ideal number. They also agree that tending to mental health concerns is hugely important for new fathers.
Eventually, after Maguire researched his condition, he recovered after time spent meditating, exercising and bonding with his son.
“A lot of new dads don’t realize how much they’re struggling because they feel ashamed or because they don’t realize it’s common shortly after the birth of a baby,” Saxbe said.
When they struggle, fathers can fixate on testosterone because that’s what modern culture tells them will make them feel better. And sometimes testosterone replacement therapy works. But Saxbe stresses a lot of men could use psychotherapy or support groups that bring dads together, as well as more time bonding with loved ones in general.
“The thing that predicts a man’s well-being and longevity is the quality of his relationships with other people,” said Saxbe. “You can be the world’s best weightlifter. You can have a low body-fat percentage. You can be killing it at work. Those things don’t predict how happy you’re going to be at 80.”
Science
Video: NASA Announces Artemis III Crew
new video loaded: NASA Announces Artemis III Crew
transcript
transcript
NASA Announces Artemis III Crew
NASA announced the crew of Artemis III mission, which will fly to low-Earth orbit to test rendezvous and docking maneuvers with one or two lunar landers.
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“I am excited to welcome you as the next crew in the Artemis journey to successfully return to the moon — this time to stay.” “I’m honored by the role that I’ve been given. I’m also very humbled by the task in front of us. But first and foremost, I’m grateful.” “So with that, the Artemis II crew, comrade, hands you the baton. You got the controls.” “As you know, we had a significant anomaly at our Launch Complex 36A on May 28. We’ve redoubled our efforts and are moving forward.”
By Alisa Shodiyev Kaff
June 9, 2026
Science
Santa Monica Mountains’ last steelhead trout survived the Palisades fire — and even had babies
Scientists feared the Santa Monica Mountains’ last remaining steelhead trout were dead, smothered by debris flows unleashed by the Palisades fire.
But the endangered fish surprised them: A team of biologists recently spotted 30 of the rare trout — and 21 babies — in Topanga Creek.
“There was a lot of happy dancing in the creek,” said Rosi Dagit, principal conservation biologist for the Resource Conservation District of the Santa Monica Mountains, which works with public and private landowners to conserve natural resources.
That’s because the steelhead here are endangered, at both the state and federal levels. Once, they swam in most streams of the Santa Monicas, but their numbers plummeted amid overfishing and coastal development. Increasingly frequent wildfire has further stressed their habitat. Topanga Creek, a biodiversity hot spot, is home to their last known population in the mountains that stretch from the Hollywood Hills to Point Mugu in Ventura County.
The trout that were spotted, including this one, are part of a distinct Southern California population that’s listed as endangered at the state and federal levels.
(RCDSMM Stream Team)
The California Department of Fish and Wildlife spearheaded a complex mission to rescue trout threatened by the Palisades fire that sparked in January 2025.
Time was of the essence. The fire hadn’t yet been fully contained. But rain was on the way, which would sweep massive amounts of sediment from the denuded hillsides into the water. Fish are often killed this way.
Crews stunned the fish with electricity, scooped them up in buckets, trucked them to a hatchery and ultimately moved them to Arroyo Hondo Creek in Santa Barbara County.
Within days, Topanga Creek was choked with mud. Some assumed the fish left behind were goners.
But in March, the conservation district’s team found four. The following month, when water conditions were clearer, they saw more.
“These fish continue to amaze me,” said Kyle Evans, environmental program manager for the state Department of Fish and Wildlife, who had seen the damage to the creek. “I had seen populations get wiped out in similar situations. So when I heard, I was thrilled.”
Evans surmises the fish that survived were in an area of the creek where less charred material and sediment were swept in.
“These fish likely hunkered down, were hiding under some rocks or places to try to get away from the main concentration of flow,” he said. “And luckily they weren’t buried.”
The ones that were spotted were fairly small, around 6 to 14 inches. Rainbow trout and steelhead trout are the same species, but with different lifestyles. If the fish remain in freshwater, they’ll be considered rainbows. However, they can migrate to the ocean and become steelhead, where they typically grow larger before returning to their natal waters to spawn.
Topanga Creek hasn’t fully recovered from the damage it sustained, but scientists say it’s looking better. Surveys last year were “so depressing,” Dagit said, with very few animals, and stretches that were essentially transformed into flat roads from all the sediment buildup. Some of the riparian canopy burned right down to the creek.
Then came 32 inches of rain over the last nine months, scouring out and moving sediment, creating deeper pools. Dagit said they recently found newt egg masses for the first time in years, as well as a few adult newts and many frogs. Plants that provide cover are starting to recover.
She provided photos comparing certain pools last year and this year, some dramatically transformed. In September 2025, the Shrine Pool could have been an overgrown hiking trail. This April, it was filled with shallow water.
The Shrine Pool in September 2025, left, and the same location in April 2026, right, with RCDSMM’s Isaac Yelchin donning a wetsuit.
(RCDSMM Stream Team)
Topanga Creek is home to another endangered fish, the small but hardy northern tidewater goby, often described as cute. Not long before the trout operation, Dagit led a rescue of hundreds of these fish too. Many were repatriated to the lagoon at the mouth of the creek in a moving ceremony last June.
There’s still the matter of what to do with the trout that were moved to Santa Barbara County last year. Evans would like to bring them home to the Santa Monicas at some point, but isn’t sure if it will happen. On one hand, they could bolster the small, genetically isolated surviving population. On the other, they might inadvertently bring in a disease or bacteria. There is some time to decide. Evans estimates the creek still needs to recover for two to three more years.
For now, the fish are functioning fine in their adopted creek. Experts worried the trauma wrought by the move would disrupt their spawning process, but they had babies that spring. This year, they spawned again.
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