Science
A Lifeboat to London for Darwin’s Frogs
The folk song “Frog Went a-Courtin’” recounts the efforts of a sword- and pistol-toting frog to woo a mouse, who warns him that without the consent of her Uncle Rat she “wouldn’t marry the president.” The courtship rituals of Darwin’s frogs, in the cool, temperate rainforests of southern South America, are not nearly as conditional. What sets their hookups apart are the child custody arrangements.
Darwin’s frogs, named after Charles Darwin, who spotted them in 1834 while exploring Chiloé Island in Chile, take an approach to parenting that is unique among amphibians: Males rear their young in their vocal sacs until the juveniles are ready to fend for themselves, a reproductive strategy known as mouth brooding.
Adult Darwin’s frogs are about an inch long and weigh less than a couple of paper clips. Although the frogs are thought to live as long as 15 years in the wild, they are highly susceptible to chytridiomycosis, a virulent amphibian disease caused by the chytrid fungus. Since the 1990s, the pathogen, which invades the surface layers of skin, has been implicated in the mass die-offs of roughly 400 amphibian species and has killed off at least 90 more.
Chiloé Island was once a sanctuary for Darwin’s frogs, but two years ago monitoring confirmed the presence of the chytrid fungus. “This is likely a result of climatic change that has made local conditions more favorable for it,” said John W. Wilkinson, a conservation biologist based in Britain.
Within a year, a chytridiomycosis outbreak had claimed more than 90 percent of the island’s Darwin’s frogs. “They die within weeks of becoming infected,” said Ben Tapley, a curator at the London Zoo who specializes in critically endangered reptiles and amphibians.
Mark O’Shea, who is a herpetologist and a co-author of the guidebook “Frogs of the World,” noted: “After pollution, habitat alteration, fragmentation and destruction, and predation by invasive species, the arrival of chytridiomycosis could be the final nail in the coffin for many stressed Darwin’s frog populations.”
In October, with the species on the brink of extinction, the London Zoo organized a rescue mission and established a captive breeding program to help save the frog from being wiped out. “There’s nothing quite like Darwin’s frogs,” Dr. Tapley said. “Their evolutionary distinctiveness is really, really striking.”
A breed apart
During breeding season, the advertisement male Darwin’s frogs use to attract females is a rapid, high-pitched whistle — piiiip, piiiip, piiiip. “It’s more of a squeak, like something metallic that needs oiling,” Dr. Tapley said.
When the female appears and the couple mates, she subsequently lays up to 40 eggs in a leaf litter, then hops away. The male stands guard over the frogspawn in a vigil that can last up to three weeks. As the larvae reach the wriggling stage, the father-in-waiting scoops them up with his tongue. The embryos pass into his vocal sac, an expandable fold of skin that reaches back to the groin. Within the membrane’s deep folds, the tadpoles develop in safety.
Some two months later, the dad, who remains silent during the incubation period and transforms from dull brown to bright green, “births” a colony of froglets through his mouth. The only other amphibian that behaves this way is the northern Darwin’s frog (Rhinoderma rufum), whose existence has not been documented since 1981 and which is presumed to be extinct.
A box of frogs
At Parque Tantauco, a private nature preserve on the southern tip of Chiloé Island, the population decline was dramatic. The London conservationists were charged with retrieving fungus-free frogs for safekeeping. Ultimately, they hope to devise treatments to mitigate the threat of the fungus.
Fifty-five specimens were rounded up during a five-day expedition. To screen for possible contamination, skin swabs were flown to a laboratory in Santiago, the Chilean capital. All but two frogs were cleared for the 7,000-mile journey to London. The 53 frogs were individually packed with ice and wet moss in climate-controlled transport boxes — two ounces of frog in a 120-pound box.
After traveling by boat, plane and van to their new digs in London, the frogs were transferred to a biosecure room that recreated the lighting, humidity and foliage of their natural habitat. “They were housed as breeding pairs to maximize genetic diversity,” Dr. Tapley said. “We plan to establish a stud book, like the ones used to maintain the pedigrees of racehorses.”
Eleven of the males turned out to be carrying young. Last month, they spit out 33 hatchlings. Each measured two-tenths of an inch, the size of a pencil eraser.
The frog in the folk song met his end in the gullet of a lily-white duck that “swallowed him up.” If London’s captive Darwin’s frogs are ever reintroduced to the rainforest, they must take their chances with the predators in southern Chile.
Science
Washington state resident dies of new H5N5 form of bird flu
The first person infected with the H5N5 bird flu has died, according to health officials in Washington.
The person, who lived in Grays Harbor County, had been hospitalized earlier this month in Kings County, where Seattle is located.
Officials from the Washington State Department of Health did not release the person’s name, age or gender. According to a news release from Grays Harbor County health officials last week, the person was considered “older” and had underlying health conditions. Their symptoms included a high fever, confusion and trouble breathing.
The person had a backyard flock consisting of mixed domestic poultry.
Testing by the health department found virus in the “environment of the flock … making exposure to the domestic poultry, their environment, or wild birds the most likely source of exposure for this patient.”
Officials at the state’s health department said they were monitoring other people who were exposed to the flock and environment.
This particular strain of bird flu, H5N5, had never been seen in a person before. It appeared first in 2023, infecting birds and mammals in eastern Canada.
According to research published last year on the novel strain, some infected animals carried a key mutation in the virus that allows it to transfer more easily between mammals.
Epidemiologists and virologists worry that avian influenza could generate a pandemic if allowed to spread and mutate. For instance, the H5N1 virus circulating in dairy cattle in North America is one mutation away from being able to spread easily between people.
Every time a bird flu virus infects a person, concerns grow that it could change, becoming more transmissible or more deadly. For instance, if a sickened person also has another flu virus replicating in their body, there’s concern the viruses could exchange genetic material. Just by having an opportunity to replicate and evolve millions of times in the human body, it could acquire deadly mutations.
Health officials say the risk to the public remains low and that no other people involved have tested positive for avian influenza. They say there is no evidence of transmission of the virus between people, but they are monitoring anyone who was in close contact with the patient.
Science
CDC replaces website on vaccines and autism with false and misleading statements
The U.S. Centers for Disease Control and Prevention has altered its website on autism and vaccines, removing unequivocal statements that immunizations don’t cause the neurodevelopmental disorder and replacing them with inaccurate and misleading information about the links between the shots and autism.
Until Wednesday, the CDC page, “Autism and Vaccines,” began: “Studies have shown that there is no link between receiving vaccines and developing autism spectrum disorder (ASD).”
This was followed, in large font, by the blunt statement: “Vaccines do not cause autism.”
The rest of the page summarized some of the CDC’s own studies into autism and vaccine ingredients, none of which found any causal links between the two.
On Wednesday, the page was altered so that it now begins: “The claim ‘vaccines do not cause autism’ is not an evidence-based claim because studies have not ruled out the possibility that infant vaccines cause autism.”
The words “Vaccines do not cause autism” still appear near the top, but with an asterisk that leads to a note at the bottom.
“The header ‘Vaccines do not cause autism’ has not been removed due to an agreement with the chair of the U.S. Senate Health, Education, Labor, and Pensions Committee that it would remain on the CDC website,” the site states.
The chair of that committee, Sen. Bill Cassidy (R-La.), cast the deciding vote to advance Robert F. Kennedy Jr.’s appointment as Health and Human Services secretary, in exchange for Kennedy’s promise that he wouldn’t erode public confidence in vaccines.
“What parents need to hear right now is vaccines for measles, polio, hepatitis B and other childhood diseases are safe and effective and will not cause autism. Any statement to the contrary is wrong, irresponsible, and actively makes Americans sicker,” Cassidy said in a post on X on Thursday afternoon. “Families are getting sick and people are dying from vaccine-preventable deaths, and that tragedy needs to stop.” Cassidy’s office did not immediately respond to further requests for comment Thursday.
“Studies supporting a link have been ignored by health authorities,” HHS spokesman Andrew Dixon said in an email. “We are updating the CDC’s website to reflect gold standard, evidence-based science.”
The news was met with outrage and alarm by scientists and advocates.
“Can we trust what’s coming from CDC anymore? I don’t know the answer to that question,” said Dr. Sean O’Leary, chair of the infectious disease committee at the American Academy of Pediatrics, adding that the website change reflects a “tragic moment” for U.S. public health.
“We are appalled to find that the content on the CDC webpage ‘Autism and Vaccines’ has been changed and distorted, and is now filled with anti-vaccine rhetoric and outright lies about vaccines and autism,” the nonprofit Autism Science Foundation said in a statement. “The CDC’s previous science- and evidence-based website has been replaced with misinformation and now actually contradicts the best available science.”
Alison Singer, the organization’s co-founder and president, expressed further frustration.
“Just like we no longer study whether the Earth is flat, at some point with regard to autism and vaccines, you have to call it and say ‘enough is enough,’” Singer said. “We don’t have an unlimited amount of money with which to study autism, and if we keep asking the same questions, we will never find the true causes of autism.”
The current CDC page now says the rise in autism diagnoses correlates with an increase in the number of vaccines given to infants. Multiple researchers have argued that the rise in autism spectrum disorder diagnoses is better explained by an expanding diagnostic definition of the disorder, along with better monitoring and diagnosis for more children.
“This issue has been studied exhaustively, and it has been shown over and over again that vaccines do not cause autism,” said Colin Killick, executive director of the Autistic Self-Advocacy Network. “This administration continues to lie about autism in ways that endanger both our community and the broader population.”
Science
California regulators approve rules to curb methane leaks and prevent fires at landfills
In one of the most important state environmental decisions this year, California air regulators adopted new rules designed to reduce methane leaks and better respond to disastrous underground fires at landfills statewide.
California Air Resources Board members voted 12-0 on Thursday to approve a batch of new regulations for the state’s nearly 200 large landfills, designed to minimize the release of methane, a powerful greenhouse gas produced by decomposing organic waste. Landfills are California’s second-largest source of methane emissions, following only the state’s large dairy cow and livestock herds.
The new requirements will force landfill operators to install additional pollution controls; more comprehensively investigate methane leaks on parts of landfills that are inaccessible with on-the-ground monitoring using new technology like drones and satellites; and fix equipment breakdowns much faster. Landfill operators also will be required to repair leaks identified through California’s new satellite-detection program.
The regulation is expected to prevent the release of 17,000 metric tons of methane annually — an amount capable of warming the atmosphere as much as 110,000 gas-fired cars driven for a year.
It also will curtail other harmful landfill pollution, such as lung-aggravating sulfur and cancer-causing benzene. Landfill operators will be required to keep better track of high temperatures and take steps to minimize the fire risks that heat could create.
There are underground fires burning in at least two landfills in Southern California — smoldering chemical reactions that are incinerating buried garbage, releasing toxic fumes and spewing liquid waste. Regulators found explosive levels of methane emanating from many other landfills across the state.
During the three-hour Air Resources Board hearing preceding the vote, several Californians who live near Chiquita Canyon Landfill — one of the known sites where garbage is burning deep underground — implored the board to act to prevent disasters in other communities across the state.
“If these rules were already updated, maybe my family wouldn’t be sick,” said Steven Howse, a 27-year resident of Val Verde. “My house wouldn’t be for sale. My close friend and neighbor would still live next door to me. And I wouldn’t be pleading with you right now. You have the power to change this.”
Landfill operators, including companies and local governments, voiced their concern about the costs and labor needed to comply with the regulation.
“We want to make sure that the rule is implementable for our communities, not unnecessarily burdensome,” said John Kennedy, a senior policy advocate for Rural County Representatives of California, a nonprofit organization representing 40 of the state’s 58 counties, many of which own and operate landfills. “While we support the overarching goals of the rule, we remain deeply concerned about specific measures including in the regulation.”
Lauren Sanchez, who was appointed chair of the California Air Resources Board in October, recently attended the United Nations’ COP30 climate conference in Brazil with Gov. Gavin Newsom. What she learned at the summit, she said, made clear to her that California’s methane emissions have international consequences, and that the state has an imperative to reduce them.
“The science is clear, acting now to reduce emissions of methane and other short-lived climate pollutants is the best way to immediately slow the pace of climate change,” Sanchez said.
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