Science
15 Lessons Scientists Learned About Us When the World Stood Still
When the pandemic upended our lives, it gave researchers a rare chance to learn more about who we are and how we live. The simultaneous changes endured by the entire world created experiments that could never have happened otherwise. What happens when sports teams play in empty stadiums? When people see their doctors online? When the government sends people money? When women stop wearing high heels? When children stop going to school?
Research was challenging in such an extraordinary period: It’s impossible to know whether changes were caused by the specific thing scientists were studying, or by some other aspect of the pandemic — or whether we could expect the same result in normal times.
Perhaps one of the most important takeaways from the pandemic was that science is a process. Just as our understandings about masks or vaccines changed as the pandemic went on, these lessons might also change with time. For now, here are 15 things we learned.
1. Flu season doesn’t have to be so bad.
Flu virtually disappeared during the pandemic. The precautions people took to prevent the spread of Covid also played a role in preventing other respiratory viruses, experts found. Slowing their spread doesn’t necessarily require extreme measures, like stay-at-home orders, the studies showed. Simple behaviors — masking, hand-washing and avoiding social gatherings or workplaces when sick — help keep people healthy. Even those precautions haven’t stuck, though: This year, flu is surging.
2. Home-field advantage got less mysterious.
When sports teams started playing in empty stadiums, researchers could more rigorously study why players seem to do better at home. A variety of studies found that, yes, the fans made a difference: Home teams played worse without them around. They were less likely to win at home and had poorer performances — and the effect was smaller for teams that had frequently played in front of smaller crowds before the pandemic. But there was also evidence that it wasn’t just about fans. When the N.B.A. restarted play, the top 22 teams isolated in Orlando, Fla., allowing researchers to study the effects of jet lag. Rebounding, shooting accuracy and wins were all higher among players who didn’t have to travel across time zones.
3. Teenagers need to sleep in, but schools won’t let them.
Most teenagers were sleep-deprived before the pandemic — they don’t naturally tend to feel tired until around 11 p.m. and need around 10 hours of sleep a night. But when schools closed, teenagers around the world started sleeping according to their natural rhythms. They went to bed later (by about two hours, one study found) and slept longer. They woke up naturally, without an alarm or a parent, which doctors say is the sign of sufficient sleep. Teenagers lost these gains when schools reopened at their usual early start times. When high schools start later, other research has shown, it’s associated with improved concentration, behavior, attendance, learning and mental health.
4. High heels aren’t just uncomfortable — they’re dangerous.
Starting in March 2020, the number of women showing up at emergency rooms with injuries they said were from wearing high heels, like fractures or sprains, declined sharply. In 2020, there were 6,300 hospital visits for high heel injuries, down from 16,000 during each of the four years prior, according to data analyzed by Philip Cohen, a sociologist at the University of Maryland. Now he’s looking into whether injuries have increased since people have begun socializing and working in offices again, or whether the pandemic has hastened the trend toward flats and sneakers.
5. Patients don’t always need to see a doctor in person, if at all.
Telehealth, once uncommon, accounted for half of medical visits early in the pandemic, found a study of two billion medical claims in the United States. Mostly, patients and doctors were satisfied with seeing one another online. Telehealth lowered health care costs, and was especially useful for treating chronic illnesses and for psychotherapy. And in some cases, the pandemic revealed, people don’t need to see a doctor at all. The number of people showing up with mild appendicitis decreased, while the number with complicated appendicitis didn’t change, which researchers said suggested that some patients who would typically have had surgery recovered on their own.
6. Women are better patients than men.
During the pandemic, women were more likely than men to wear masks, get vaccinated and follow other public health guidance. This was true in many countries. When men and women lived together, the men were a little more likely to follow health rules, but still less likely than the women. One group of researchers studied professional tennis players at the U.S. Open in 2020. The women were more likely than the men to skip the event because of safety concerns. This aligns with gender differences in health overall, researchers said — women are more likely to seek preventive care, visit doctors and follow health recommendations. It’s probably one reason women tend to live longer.
7. Not even being stuck at home makes men do more housework.
During lockdowns, there was a lot more domestic labor to do. More dishes piled up, with more needy children underfoot. But even when men worked from home, women still handled more of the work. Eight in 10 mothers said they managed remote schooling (fathers overestimated their contribution). That could be a reason mothers’ antidepressant use increased when schools were closed, but not fathers’. Mothers were also more likely than men to cut back at work — though they returned as soon as they could. Only couples who really wanted egalitarian relationships, researchers wrote, could overcome “the stickiness of gender inequality in household work.”
8. Alcohol restrictions can save lives.
Many places had curfews or bans on selling alcohol during lockdowns — and it appeared to have saved lives. In South Africa, hospital admissions to trauma units and deaths declined. In Southern India, traumatic brain injuries decreased. In other parts of the world, however, alcohol use increased significantly — and, along with it, domestic violence and other problems.
9. Office workers don’t need to be chained to their desks.
Even without in-person meetings, work travel and days spent in cubicles, business continued on. The lesson, said Nick Bloom, a Stanford economist: “Work from home works.” Researchers are still studying how remote work affects productivity, collaboration and creativity. But some version of it seems here to stay: Just over a quarter of paid work days are now worked from home, compared with about 7 percent prepandemic. Remote work has downsides — for innovation, mentorship and service jobs in downtowns. But it also has benefits that workers aren’t eager to give up, like no commutes, more focused work time and making it easier for parents to juggle child care. As a result, it also improves retention.
10. Computers are no replacement for classrooms.
Five years later, the data is clear: When it came to learning, remote school wasn’t enough. Across the country, in rich and poor districts, and among students of different races, test scores in reading and math fell. Many students still haven’t caught up. There was learning loss even in countries with much shorter school closures than the United States. Other factors hampered students’ learning, including poverty and stress, but the importance of attending school in person is clear: The sooner children returned to classrooms, even part-time, the better they did.
11. There’s a simple way to bring children out of poverty.
The monthly checks that the U.S. government sent most parents during the pandemic were enormously successful in bringing children out of poverty, a variety of research has found. Families used the money to pay for food, child care, health care and housing. The benefits weren’t just financial — the checks improved parents’ mental health and family well-being. In 2022, when the checks ended, child poverty doubled. The expanded child credit was part of a rapid $5 trillion expansion of the social safety net.
12. Premature births might be prevented by taking care of moms.
The first reports came from Denmark and Ireland in 2020: The number of babies born premature or at a very low birth weight plummeted early in the pandemic. Soon it became clear that this trend was global: One study estimated that worldwide, 50,000 premature births — a leading cause of infant mortality — had been prevented in just the first month of the pandemic. Researchers aren’t sure exactly why, but a leading theory is that staying home benefited pregnant women — they could rest more, and were exposed to fewer stressors, pollutants and viruses. Perhaps giving pregnant women a break would make them, and their babies, healthier.
13. Dolphins talk more when people aren’t around.
When humans were less active — what scientists call the anthropause — animals began breeding more and traveling farther. Dolphins whistled longer, birds changed their songs, sea turtles laid more eggs. But the anthropause also revealed the ways in which animals have adapted to people, and humans’ disappearance disturbed delicate balances. In some places, predators or invasive species arrived. Urban wildlife that had become accustomed to coexisting with humans, like crows or raccoons, retreated. It revealed the ways in which humans both threaten and protect the natural world, scientists said.
14. Trees and plants make people happier.
Unable to spend time in indoor public spaces, people flocked to natural areas when they could, and were better off for it. A study in Hong Kong compared people who lived near urban green spaces with those who didn’t, and found that parks provided physical activity and a refuge. A study in nine countries found that access to nature — even a balcony or garden at home — buffered the stress of lockdowns and improved people’s moods. And a study in Taiwan analyzed the “window/wall ratio” in people’s quarantine rooms and found that more windows, especially if people could see vegetation, made them happier.
15. There’s no substitute for human contact.
Across the globe, when people didn’t see other people, their mental health — as measured by loneliness, depression and anxiety — got worse. Social media was not a substitute, and often made mental health deteriorate. The pandemic made clear that socializing is particularly important for two age groups, researchers said: young adults and older adults. The older group had better mental health, as well as cardiovascular and cognitive health, when they had structured socializing, like activities at community centers or weekly visits or phone calls.
Science
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Science
Tuberculosis outbreak reported at Catholic high school in Bay Area. Cases statewide are climbing
Public health officials in Northern California are investigating a tuberculosis outbreak, identifying more than 50 cases at a private Catholic high school and ordering those who are infected to stay home. The outbreak comes as tuberculosis cases have been on the rise statewide since 2023.
The San Francisco Department of Public Health issued a health advisory last week after identifying three active cases and 50 latent cases of tuberculosis at Archbishop Riordan High School in San Francisco. The disease attacks the lungs and remains in the body for years before becoming potentially deadly.
A person with active TB can develop symptoms and is infectious; a person with a latent tuberculosis infection cannot spread the bacteria to others and doesn’t feel sick. However, a person with a latent TB infection is at risk of developing the disease anytime.
The three cases of active TB have been diagnosed at the school since November, according to public health officials. The additional cases of latent TB have been identified in people within the school community.
Archbishop Riordan High School, which recently transitioned from 70 years of exclusively admitting male students to becoming co-ed in 2020, did not immediately respond to the The Times’ request for comment.
School officials told NBC Bay Area news that in-person classes had been canceled and would resume Feb. 9, with hybrid learning in place until Feb. 20. Students who test negative for tuberculosis will be allowed to return to campus even after hybrid learning commences.
Officials with the San Francisco Department of Public Health said the risk to the general population was low. Health officials are currently focused on the high school community.
How serious is a TB diagnosis?
Active TB disease is treatable and curable with appropriate antibiotics if it is identified promptly; some cases require hospitalization. But the percentage of people who have died from the disease is increasing significantly, officials said.
In 2010, 8.4% of Californians with TB died, according to the California Department of Public Health. In 2022, 14% of people in the state with TB died, the highest rate since 1995. Of those who died, 22% died before receiving TB treatment.
The Centers for Disease Control and Prevention estimated that up to 13 million people nationwide live with latent TB.
How does California’s TB rate compare to the country?
Public health officials reported that California’s annual TB incidence rate was 5.4 cases per 100,000 people last year, nearly double the national incidence rate of 3.0 per 100,000 in 2023.
In 2024, 2,109 California residents were reported to have TB compared to 2,114 in 2023 — the latter was about the same as the total number of cases reported in 2019, according to the state Department of Public Health.
The number of TB cases in the state has remained consistent from 2,000 to 2,200 cases since 2012, except during the COVID-19 pandemic from 2020 to 2022.
California’s high TB rates could be caused by a large portion of the population traveling to areas where TB is endemic, said Dr. Shruti Gohil, associate medical director for UCI Health Epidemiology and Infection Prevention.
Nationally, the rates of TB cases have increased in the years following the COVID-19 pandemic, which “was in some ways anticipated,” said Gohil. The increasing number of TB cases nationwide could be due to a disruption in routine care during the pandemic and a boom in travel post-pandemic.
Routine screening is vital in catching latent TB, which can lie dormant in the body for decades. If the illness is identified, treatment could stop it from becoming active. This type of routine screening wasn’t accessible during the pandemic, when healthcare was limited to emergency or essential visits only, Gohil said.
When pandemic restrictions on travel were lifted, people started to travel again and visit areas where TB is endemic, including Asia, Europe and South America, she said.
To address the uptick in cases and suppress spread, Gov. Gavin Newsom signed Assembly Bill 2132 into law in 2024, which requires adult patients receiving primary care services to be offered tuberculosis screening if risk factors are identified. The law went into effect in 2025.
What is TB?
In the United States, tuberculosis is caused by a germ called Mycobacterium tuberculosis, which primarily affects the lungs and can impact other parts of the body such as the brain, kidneys and spine, according to the Centers for Disease Control and Prevention. If not treated properly, TB can be fatal.
TB is spread through the air when an infected person speaks, coughs or sings and a nearby person breathes in the germs.
When a person breathes in the TB germs, they settle in the lungs and can spread through the blood to other parts of the body.
The symptoms of active TB include:
- A cough that lasts three weeks or longer
- Chest pain
- Coughing up blood or phlegm
- Weakness or fatigue
- Weight loss
- Loss of appetite
- Chills
- Fever
- Night sweats
Generally, who is at risk of contracting TB?
Those at higher risk of contracting TB are people who have traveled outside the United States to places where TB rates are high including Asia, the Middle East, Africa, Eastern Europe and Latin America.
A person has an increased risk of getting TB if they live or work in such locations as hospitals, homeless shelters, correctional facilities and nursing homes, according to the CDC.
People with weakened immune systems caused by health conditions that include HIV infection, diabetes, silicosis and severe kidney disease have a higher risk of getting TB.
Others at higher risk of contracting the disease include babies and young children.
Science
Contributor: Animal testing slows medical progress. It wastes money. It’s wrong
I am living with ALS, or amyotrophic lateral sclerosis, often called Lou Gehrig’s disease. The average survival time after diagnosis is two to five years. I’m in year two.
When you have a disease like ALS, you learn how slowly medical research moves, and how often it fails the people it is supposed to save. You also learn how precious time is.
For decades, the dominant pathway for developing new drugs has relied on animal testing. Most of us grew up believing this was unavoidable: that laboratories full of caged animals were simply the price of medical progress. But experts have known for a long time that data tell a very different story.
The Los Angeles Times reported in 2017: “Roughly 90% of drugs that succeed in animal tests ultimately fail in people, after hundreds of millions of dollars have already been spent.”
The Times editorial board summed it up in 2018: “Animal experiments are expensive, slow and frequently misleading — a major reason why so many drugs that appear promising in animals fail in human trials.”
Then there’s the ethical cost — confining, sickening and killing millions of animals each year for a system that fails 9 times out of 10. As Jane Goodall put it, “We have the choice to use alternatives to animal testing that are not cruel, not unethical, and often more effective.”
Despite overwhelming evidence and well-reasoned arguments against animal-based pipelines, they remain central to U.S. medical research. Funding agencies, academic medical centers, government labs, pharmaceutical companies and even professional societies have been painfully slow to move toward human- and technology-based approaches.
Yet medical journals are filled with successes involving organoids (mini-organs grown in a lab), induced pluripotent stem cells, organ-on-a-chip systems (tiny devices with human cells inside), AI-driven modeling and 3D-bioprinted human tissues. These tools are already transforming how we understand disease.
In ALS research, induced pluripotent stem cells have allowed scientists to grow motor neurons in a dish, using cells derived from actual patients. Researchers have learned how ALS-linked mutations damage those neurons, identified drug candidates that never appeared in animal models and even created personalized “test beds” for individual patients’ cells.
Human-centric pipelines can be dramatically faster. Some are reported to be up to 10 times quicker than animal-based approaches. AI-driven human biology simulations and digital “twins” can test thousands of drug candidates in silico, with a simulation. Some models achieve results hundreds, even thousands, of times faster than conventional animal testing.
For the 30 million Americans living with chronic or fatal diseases, these advances are tantalizing glimpses of a future in which we might not have to suffer and die while waiting for systems that don’t work.
So why aren’t these tools delivering drugs and therapies at scale right now?
The answer is institutional resistance, a force so powerful it can feel almost god-like. As Pulitzer Prize–winning columnist Kathleen Parker wrote in 2021, drug companies and the scientific community “likely will fight … just as they have in past years, if only because they don’t want to change how they do business.”
She reminds us that we’ve seen this before. During the AIDS crisis, activists pushed regulators to move promising drugs rapidly into human testing. Those efforts helped transform AIDS from a death sentence into a chronic condition. We also saw human-centered pipelines deliver COVID vaccines in a matter of months.
Which brings me, surprisingly, to Robert F. Kennedy Jr. In December, Kennedy told Fox News that leaders across the Department of Health and Human Services are “deeply committed to ending animal experimentation.” A department spokesperson later confirmed to CBS News that the agency is “prioritizing human-based research.”
Kennedy is right.
His directive to wind down animal testing is not anti-science. It is pro-patient, pro-ethics and pro-progress. For people like me, living on borrowed time, it is not just good policy, it is hope — and a potential lifeline.
The pressure to end animal testing and let humans step up isn’t new. But it’s getting new traction. The actor Eric Dane, profiled about his personal fight with ALS, speaks for many of us when he expresses his wish to contribute as a test subject: “Not to be overly morbid, but you know, if I’m going out, I’m gonna go out helping somebody.”
If I’m going out, I’d like to go out helping somebody, too.
Kevin J. Morrison is a San Francisco-based writer and ALS activist.
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