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Republican majority at risk? A look at the 6 GOP Senate seats most in jeopardy in midterm elections

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Republican majority at risk? A look at the 6 GOP Senate seats most in jeopardy in midterm elections

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The Senate Republican campaign chair has a stark warning for his party as the GOP defends its 53-47 majority in the chamber in this year’s midterm elections.

National Republican Senatorial Committee (NRSC) Chair Tim Scott, pointing to a ballot box deficit the GOP’s facing in the latest Fox News national poll, said it could impact specific Senate races this year.

And Scott said the toughest challenge may be in Maine, where longtime Republican Sen. Susan Collins is running for re-election for a sixth six-year term in the blue-leaning northern New England state.

The straight talk from Scott, at a closed-door meeting earlier this week with fellow GOP senators, comes as Republicans, as the party in power in the nation’s capital, face traditional political headwinds in the midterms. And the GOP is also facing a rough political climate, with President Donald Trump‘s approval ratings remaining underwater while Democrats are energized as they work to win back the House majority and possibly recapture the Senate.

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An exterior view of the Senate side of the U.S. Capitol, on Jan. 12, 2026. (Paul Steinhauser/Fox News)

While the NRSC remains optimistic that it can not only defend but expand their majority, the GOP will be playing defense in half a dozen key races.

Here’s a look at the most vulnerable Republican Senate seats up for grabs in the midterms.

Maine

Collins is the only Republican senator running for re-election this year in a state that then-Vice President Kamala Harris carried in her 2024 presidential election defeat to Trump.

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And Collins has seen a deterioration of her poll numbers among Mainers from her last re-election six years ago.

But Collins, who has long been a top target of the rival Democratic Senatorial Campaign Committee (DSCC) has proven tough to beat.

Sen. Susan Collins, R-Maine, departs the chamber at the Capitol in Washington, on July 24, 2025. (J. Scott Applewhite/AP Photo)

Complicating the Democrats’ push to flip the seat is a competitive primary between two-term Democratic Gov. Janet Mills, who has the tacit backing of longtime Senate Democratic Leader Chuck Schumer and the DSCC, and veteran and oyster farmer Graham Platner, who is running to the left of the governor and who is backed by progressive champion Sen. Bernie Sanders of Vermont.

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North Carolina

Republicans are defending an open seat in the southeastern battleground state, with GOP Sen. Thom Tillis retiring at the end of this year.

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Democrats landed their top recruit when former two-term Gov. Roy Cooper launched a Senate campaign last summer. Cooper enjoys tons of name ID in North Carolina and is 6-0 when running statewide races.

Republicans are rallying around former Republican National Committee (RNC) Chair Michael Whatley, who has the president’s backing.

RNC Chair Michael Whatley announces his run for Senator for North Carolina on July 31st, 2025 in Gastonia, N.C. (Paul Steinhauser/Fox News)

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The race is expected to be one of the most expensive and competitive Senate showdowns this year.

Ohio

Democrats scored another major recruiting victory when former longtime Sen. Sherrod Brown announced he would challenge Republican Sen. Jon Husted.

A former lieutenant governor, Husted was appointed to the Senate a year ago after then-Sen. JD Vance stepped down to serve as vice president.

Sen. Jon Husted, R-Ohio, who was appointed to fill now-Vice President JD Vance’s seat, is running in the midterms to serve the final two years of Vance’s term. (Getty Images)

Ohio, once a premiere general election battleground, has turned red over the past decade, and Democrats view Brown as their only competitive candidate in the race to serve the final two years of Vance’s term.

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Brown lost re-election in 2024 by roughly four points while Trump carried Ohio by 11 points.

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Similar to North Carolina, the showdown is expected to be very expensive and competitive.

Alaska

Democrats were given a big boost in the red-leaning state when former Rep. Mary Peltola announced last month that she would challenge GOP incumbent Sen. Dan Sullivan.

Sen. Dan Sullivan, R-Alaska, is running for re-election in this year’s midterms. (Allison Robbert/AFP via Getty Images)

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Peltola lost re-election 15 months ago in the at-large district that covers the entire state by three points, while Trump carried Alaska by 11 points.

Iowa

Republicans are defending an open seat in Iowa, a onetime swing state that’s shifted to the right over the past decade.

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But the GOP has rallied around Rep. Ashley Hinson, who is backed by Trump, in the race to succeed retiring Republican Sen. Joni Ernst.

Republican Rep. Ashley Hinson of Iowa, who is running in the 2026 race to succeed retiring GOP Sen. Joni Ernst, sits for a Fox News Digital interview on Sept. 4, 2025, in Washington, D.C. (Paul Steinhauser – Fox News )

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Hinson, a former local TV news anchor who flipped a Democratic-held seat in 2020, is seen as a rising star in the party.

Democrats have a contested primary that includes state Rep. Josh Turek, a Paralympian, state Sen. Zach Wahls and military veteran Nathan Sage.

Texas

Longtime Republican Sen. John Cornyn of Texas is in the middle of a competitive and combustible GOP nomination battle against state Attorney Gen. Ken Paxton and Rep. Wesley Hunt.

Trump, to date, has stayed neutral in the primary, which will be held early next month.

Sen. John Cornyn, R-Texas, is facing a combustible GOP primary as he seeks re-election in this year’s midterms. (Tom Williams/CQ-Roll Call, Inc via Getty Images)

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If neither Cornyn, Paxton, nor Hunt wins a majority of the vote next month, a runoff will be held in May.

Cornyn enjoys the backing of Senate Majority Leader John Thune and the NRSC, which worries that the seat would be vulnerable if Paxton, who has plenty of political baggage, wins the primary.

The Democrats, who are eyeing the seat in the right-leaning state, have a competitive contest for their nomination between progressive firebrand and vocal Trump critic Rep. Jasmine Crockett and state Rep. James Talarico, a rising star in the party.

GOP on offense

While playing defense, the NRSC is also eyeing three Democratic-held Senate seats.

The GOP’s aiming to flip open seats in battleground Michigan, where Sen. Gary Peters is retiring, and swing state New Hampshire, where longtime Sen. Jeanne Shaheen is ending her long career, in which she made history as the first woman elected governor and senator.

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Republicans are also eyeing battleground Georgia, where they view first-term Sen. Jon Ossoff as the most vulnerable Democrat seeking re-election this year.

The NRSC is also spotlighting the open Senate seat in blue-leaning Minnesota, where Democratic Sen. Tina Smith is retiring.

Former longtime sportscaster Michele Tafoya is being backed by the NRSC as she runs for the GOP nomination.

Michele Tafoya is interviewed by Fox News Digital as she launches a Republican Senate campaign in Minnesota. (Paul Steinhauser/Fox News)

Some Republicans are calling last weekend’s double-digit shellacking in a special state Senate election in Texas in a district Trump carried by 17 points in 2024 a wake up call.

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The stunning ballot box setback for Republicans, coming amid backlash over the Trump administration’s unprecedented crackdown on illegal immigration, is further energizing Democrats as they aim to win back congressional majorities.

The victory in Texas was the Democrats’ latest win or over performance in a slew of elections since Trump returned to power in the White House a year ago, as the party stays laser focused on the issue of affordability amid persistent inflation.

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“The White House needs to focus less on foreign policy and immigration and more on affordability to improve our chances in the midterms,” Dan Eberhart, an oil drilling chief executive officer and a prominent Republican donor and bundler, told Fox News Digital.

And Eberhart, pointing to some key Senate races, said he’s worried about “the money game.”

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“We’re woefully behind in Georgia. We’re behind in North Carolina. I think that in Texas we’re going to have somebody limp out of a runoff,” he cautioned.

Thune, speaking to reporters this week following the NRSC briefing, said that “the Democrats are targeting a number of our incumbents. And so we’ve got some races that are going to be expensive and hard fought in places like Maine and North Carolina.”

But Thune added, “We feel really good about … where our Senate races are.” And he emphasized that “incumbents in our conference are seasoned veterans who will outwork any of their opponents.”

Meanwhile, DSCC Chair Sen. Kirsten Gillibrand told Fox News Digital last month that “President Trump is creating a toxic agenda that’s harming people.”

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And Gillibrand emphasized she’s “optimistic that we have a shot to take back the majority.”

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Maine

Wet, cooler today; rain & snow impacts across Maine

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Wet, cooler today; rain & snow impacts across Maine


BANGOR, Maine (WABI) – Good morning and Happy Sunday everyone. Skies are cloudy with fog across much of Maine this morning. Rain has entered locations along the interstate and to the northwest. Temperatures vary from the upper 30s to mid 40s. Winds are out of the SE between about 5-15 mph.

Today will be a wet and impactful day with rain and even snow anticipated as a large cold front passes through Maine. Skies will be cloudy with plenty of fog lasting through the morning. Rain will expand across the interstate by the late morning hours, reaching Downeast locations by midday/the early afternoon.

By the early to midafternoon, temperatures will start to drop across northwestern locations as the cold front passes through Maine. This will result in rain turning over to mixed precipitation and eventually snow across the Western Mountains, Moosehead region, and Northern Maine. Rain will continue steadily and at times heavily across the foothills, Interstate, Coast, and Downeast. A few thunderstorms are even possible closer to the coast.

Snow will expand across areas to the northwest of the interstate this evening, reaching all the way down to Interior Midcoast communities, the Bangor region, and Interior Downeast areas by sunset and into the start of the night. Precipitation will taper off across Western Maine shortly after sunset, before exiting the entire state around midnight tonight. High temps today will vary from the low 40s to low 50s with SSE to NW gusts reaching 20-25 mph.

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WABI Weather 4/19/26 AM(WABI)

Snowfall totals will vary under 2 inches across Western, Northern, and Interior Downeast locations. However, a few pockets of 2-4 inches are possible, mostly in higher elevations across the mountains. Rainfall totals will accumulate around a half inch to three quarters of an inch when all is said and done.

WABI Weather 4/19/26 AM
WABI Weather 4/19/26 AM(WABI)
WABI Weather 4/19/26 AM
WABI Weather 4/19/26 AM(WABI)

Precipitation will be out of Maine by midnight tonight, with cloudy conditions giving way to mostly clear skies by sunrise. Lows overnight will dip back below freezing across much of the state, from the low 20s to mid 30s tonight, so cover up any plants or flowers outside. WNW gusts will reach 20-25 mph. A Small Craft Advisory is expected offshore.

WABI Weather 4/19/26 AM
WABI Weather 4/19/26 AM(WABI)

Skies will be partly to mostly sunny across the interstate and coast on Monday morning. However, by the late morning to midday hours, clouds will build with a few scattered rain and snow showers in spots. Conditions will remain on the cloudier side in the afternoon before clearing up around sunset into the start of Monday night. Highs will be chilly on Monday, from the low 30s to upper 40s. WNW to SW gusts will be a bit breezy, reaching 20-25 mph, which will add to the wind chill factor.

WABI Weather 4/19/26 AM
WABI Weather 4/19/26 AM(WABI)

High pressure will build on Monday night, remaining overhead on Tuesday. Skies will be sunny in the morning, becoming partly to mostly sunny in the afternoon. Highs will remain cool, in the 40s across the board with North to SW gusts only reaching 15-20 mph.

A weaker low-pressure system could bring showers across Maine on Wednesday and Thursday. There is a bit of model uncertainty on exactly when it will impact Maine. The GFS has impacts on Wednesday, while the EURO, GRAF, and GDPS models have most of the impacts on Thursday. We will continue to monitor this system and potential impacts. All it looks to provide as of now are cloudier skies and rain showers, with some snow shower chances farther to the North.

By Friday and Saturday, conditions are trending on the drier side with sunshine and average temperatures returning to the forecast.

WABI Weather 4/19/26 AM
WABI Weather 4/19/26 AM(WABI)

SUNDAY: Highs from low 40s to low 50s. Cloudy with AM fog. Rain becoming widespread throughout the day, turning over to snow to the north & west during PM. SSE to NW gusts reach 20-25 mph.

MONDAY: Highs from low 30s to upper 40s. Partly to mostly sunny early. Developing clouds with scattered rain/snow showers by midday/afternoon. WNW to SW gusts reach 20-25 mph.

TUESDAY: Highs throughout the 40s. Sunnier AM. Partly to mostly sunny PM. North to SW gusts reach 15-20 mph.

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WEDNESDAY: Highs from low 40s to low 50s. Mostly cloudy with a few rain showers. Few AM snow showers possible North. SSE to SSW gusts reach 20-25 mph.

THURSDAY: Highs from mid 40s to mid 50s. Cloudier skies with rain showers possible. Some AM snow showers possible North. NW gusts reach 20-25 mph.

FRIDAY: Highs from upper 40s to mid 50s. Partly cloudy. NNW gusts reach 20 mph.

Copyright 2026 WABI. All rights reserved.



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Massachusetts

New Bedford MS-13 Member, Illegal Alien Pleads Guilty to Role in Brutal Murders In Massachusetts, Virginia

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New Bedford MS-13 Member, Illegal Alien Pleads Guilty to Role in Brutal Murders In Massachusetts, Virginia


A 28-year-old Salvadoran national and admitted member of the MS-13 gang, who was living unlawfully in New Bedford, Massachusetts, pleaded guilty in federal court in Boston to his role in three brutal murders committed to advance the gang’s violent agenda across Massachusetts and Virginia.

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New Hampshire

‘Not cosmetic’: NH lawmaker wants state to cover GLP-1 drugs for weight loss – Concord Monitor

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‘Not cosmetic’: NH lawmaker wants state to cover GLP-1 drugs for weight loss – Concord Monitor


Two years ago, Sue Prentiss got a sobering reality check at her doctor’s office. The news was blunt: She qualified for bariatric surgery, a procedure for patients whose weight poses life-threatening risks.

She was aware of her weight and had tried everything from high-intensity workouts to weight loss programs and diets. Nothing seemed to help until she started taking GLP-1 medications.

Prentiss said between then and now, she had lost almost 80 pounds. 

But at a $500 out-of-pocket monthly fee, every refill is a financial pinch.

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“I’m just getting by, but I’m so much healthier, and if this can work for me, think about everybody else’s life where this would impact,” said Prentiss, a state senator.

To keep up with the cost, she’s made hard choices like cutting back on retirement contributions and squeezing her budget wherever possible.

Sen. Sue Prentiss Credit: Courtesy

Now, Prentiss is sponsoring Senate Bill 455, which would require the state to provide GLP-1 medications under the state Medicaid plan as a treatment for people with obesity.

As of January, New Hampshire’s Medicaid program has ended coverage for GLP-1 drugs like Saxenda, Wegovy and Zepbound for weight loss. The state still covers the medications when they’re part of a treatment plan for other chronic conditions, such as type 2 diabetes, certain cardiovascular diseases, severe sleep apnea and Metabolic Dysfunction-Associated Steatohepatitis (MASH).

According to the New Hampshire Department of Health and Human Services, the state paid managed care organizations $49.5 million to cover GLP-1 medications between July 1, 2025, and June 30, 2026. The policy change in January reduced that cost to $41 million.

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With these drugs gaining popularity, the state estimated that if were to resume covering GLP-1s for weight loss, it would need to spend an additional $24.2 million on top of the $41 million per fiscal year.

Jonathan Ballard, chief medical officer at DHHS, said the agency opposes the bill, which would require Medicaid coverage for anyone with a body mass index above 30 seeking GLP-1 medications specifically for weight loss.

Ballard said the state cannot afford such an expansion when budgets are already tight.

“The department does not have this money today,” he said. “So, living within the realities of our current budget, there will be significant trade-offs. We will have to cut other things that are very important to the health and well-being of New Hampshire to pay for this unless there’s some change.”

GLP-1 drugs carry a steep price tag that puts significant pressure on state budgets, particularly within Medicaid programs. Several states, including California, Pennsylvania and South Carolina, have moved to drop coverage of these medications for weight loss.

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Prentiss initially drafted her legislation with private insurers in mind, but later pivoted to focus on Medicaid to serve more vulnerable populations. She is covered by commercial insurance and said the outcome of the bill will not personally affect her.

Lost coverage

GLP-1 medications mimic a natural hormone in the gut that helps regulate blood sugar, digestion and appetite.

Sarah Finn, section chief for obesity medicine at Dartmouth Health, said she has seen firsthand the impact on her patients after the state dropped Medicaid coverage for weight-loss GLP-1 drugs. 

Without access to these medications, patients experience increased hunger, cravings and persistent “food noise,” as their bodies attempt to return to a higher fat percentage, a process known as metabolic adaptation, she said.

“This is the reality of the state I’m in right now, where I don’t have options except bariatric surgery for my Medicaid patients and a lot of times patients don’t want to do a surgery,” said Finn, at a hearing for the bill on Wednesday. “What I have to tell that patient is there’s nothing I could do to advocate.”

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The Department of Health and Human Services faced a $51 million budget cut when the New Hampshire Legislature passed its biennial budget last year, forcing the department to reduce several services.

While Prentiss acknowledges the financial strain on the department, she wants the state to consider the long-term impact of using GLP-1s to prevent chronic conditions like diabetes, which is largely linked to weight gain and can drive up costs for the state over time.

“By driving down obesity, we can drive down the costs that are related to it,” she said. 

Prentiss remains on GLP-1 medications and said she feels much healthier than before.

She said that after a few months on the drugs, her blood sugar levels and kidney function began trending toward more normal ranges.

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“It’s not cosmetic,” she said. “Obesity is a medical condition.”



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