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Vaccine researchers in Pittsburgh join new pandemic preparedness network
PITTSBURGH (KDKA) — After the COVID-19 pandemic wreaked havoc, Pittsburgh researchers are doing everything they can to help prevent another devastating pandemic from happening again.
Most of us would like to forget the COVID-19 pandemic, but it’s a motivator for the people who study dangerous viruses at the Center for Vaccine Research at the University of Pittsburgh.
“People like us in the Center for Vaccine Research have to remember that it existed and have to be ready for the next one,” said Paul Duprex, director of Pitt’s Center for Vaccine Research.
Duprex is thrilled the center is joining a new National Institutes of Health network. The Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness network, ReVAMPP, is aimed at boosting pandemic preparedness.
He said they’ll receive millions of dollars in awards over the next three to five years to come up with plans that can be used to quickly respond to virus threats.
The experts at Pitt will study prototype viruses from four troublemaker virus families — like the family that includes mumps, for example.
“If you imagine that a virus, which is very closely related to mumps but is transmissible as mumps comes along and we don’t have natural immunity to that because the mumps vaccine that we have is not protective, we can take that knowledge, which we identify for mumps, and use it to quickly generate a new vaccine,” Duprex said.
To put it simply, they’re using examples to prepare for something that emerges in the future.
“We can take all of that knowledge and pivot that knowledge into this new virus that we’ve never seen before,’ he said.
Duprex said CVR’s regional bio-containment lab will benefit the program greatly. Researchers there worked with coronavirus, SARS, MERS and more.
“We take advantage of all of that knowledge that we built, all of that expertise we have, not to look backwards but to look forwards,” he said.
He said the “prototype pathogens” model is similar to the one that accelerated vaccines to fight the virus that caused the COVID-19 pandemic.
The NIH’s National Institute of Allergy and Infectious Diseases expects to commit $100 million per year to fund the ReVAMPP program. Multi-million dollar rewards will go to multiple research groups that make up the network across the U.S.
Duprex is proud Pitt researchers are a part of this new network. They’re ready to suit up in full protective gear and develop blueprints that could be life-saving.
“If you think about it as seven families, lots of scientists, lots of virology, lots of vaccinology, lots of preparation with a view to be ready to move. It’s super exciting. It’s just wonderful that we get to play a part in it,” Duprex said.
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Pittsburgh Today Live Chat: November 21, 2024
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Allegheny Co. Executive Innamorato continues push for council to pass proposed budget
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Paul Skenes finishes third in NL Cy Young Award voting
PITTSBURGH (KDKA) — Pittsburgh Pirates pitcher Paul Skenes finished third in the National League Cy Young Award voting on Wednesday.
Atlanta Braves pitcher Chris Sale won the award, while Philadelphia Phillies pitcher Zack Wheeler finished second.
The Pirates’ pitcher is the fifth rookie to finish in the top 3 in Cy Young voting, and his third-place finish is the highest by a rookie since Jose Fernandez’s third-place mark in 2013. Skenes received one second-place vote and 13 third-place votes. The award was voted on by the Baseball Writers’ Association of America.
For Skenes, Wednesday’s Cy Young third-place finish was the cap on a phenomenal rookie season. From May 11, when he made his Major League Baseball Debut, Skenes was a sensation on the mound. He finished the season with an 11-3 record and a 1.96 ERA in 133 innings over 23 starts. He added 170 strikeouts and only walked 32 batters.
The 22-year-old pitcher, the No. 1 pick in the 2023 draft out of LSU, had such a strong season that he was named the starting pitcher for the National League in the 2024 All-Star Game.
Though Skenes came up short in the NL Cy Young voting, the pitcher was named the 2024 NL Jackie Robinson Rookie of the Year winner on Monday.
The pitcher also was named Baseball Digest’s National League Rookie of the Year earlier this month and Baseball America’s 2024 Rookie of the Year in October.
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