Week 10 of the 2025 college football season continues on Wednesday night when the Missouri State Bears host the FIU Panthers in a Conference USA battle.

The Bears come into Wednesday on a two-game winning streak, and it has pushed their record to 4-3 overall and 2-1 in the CUSA. They are near the top of the conference in their first year in the FBS.

The Panthers have been going the other direction as they have lost three of their last four games and it has dropped them to 3-4 overall and 1-2 in the conference.

Stream Missouri State vs. FIU

If you’re looking to get back in the swing of football season and need some betting advice for Wednesday’s matchup in Springfield, we’ve got you covered. Here are the latest odds for the game, courtesy of BetMGM.

Missouri State vs FIU game odds:

All college football odds via BetMGM

• Spread: Missouri State -3.5 (-115), FIU +3.5 (-105)
• Money Line: Missouri State -190, FIU +155
• Over-Under: Over 50.5 (-110), Under 50.5 (-110)

Missouri State vs FIU prediction, pick:

The Bears have been finding ways to win over the last two weeks, while the Panthers have been getting blown out. The Panthers have been struggling on defense, giving up 28 or more points in five of their last six games. The Bears haven’t exactly been putting up a ton of points, but their defense has played well. They are also at home, and that will make the difference. They hold down the Panthers and do enough offensively to cover and get their third straight win.

Prediction: Missouri State 27, FIU 17

Best Bet: Missouri State -3.5, Under 50.5

Missouri State vs FIU channel, start time, streaming:

Time: 8 p.m. ET

TV Channel: CBS Sports Network

Live Stream: Paramount+

Get more betting analysis and predictions at Sportsbook Wire.

Contact/Follow @College_Wire on X and @College_Wires on Threads. Like our page on Facebook to follow ongoing coverage of college sports news, notes, and opinions.

State

AlabamaAlaskaArizonaArkansasCaliforniaColoradoConnecticutDelawareFloridaGeorgiaHawaiiIdahoIllinoisIndianaIowaKansasKentuckyLouisianaMaineMarylandMassachusettsMichiganMinnesotaMississippiMissouriMontanaNebraskaNevadaNew HampshireNew JerseyNew MexicoNew YorkNorth CarolinaNorth DakotaOhioOklahomaOregonPennsylvaniaRhode IslandSouth CarolinaSouth DakotaTennesseeTexasUtahVermontVirginiaWashingtonWashington D.C.West VirginiaWisconsinWyomingPuerto RicoUS Virgin IslandsArmed Forces AmericasArmed Forces PacificArmed Forces EuropeNorthern Mariana IslandsMarshall IslandsAmerican SamoaFederated States of MicronesiaGuamPalauAlberta, CanadaBritish Columbia, CanadaManitoba, CanadaNew Brunswick, CanadaNewfoundland, CanadaNova Scotia, CanadaNorthwest Territories, CanadaNunavut, CanadaOntario, CanadaPrince Edward Island, CanadaQuebec, CanadaSaskatchewan, CanadaYukon Territory, Canada

Zip Code

Country

United States of AmericaUS Virgin IslandsUnited States Minor Outlying IslandsCanadaMexico, United Mexican StatesBahamas, Commonwealth of theCuba, Republic ofDominican RepublicHaiti, Republic ofJamaicaAfghanistanAlbania, People’s Socialist Republic ofAlgeria, People’s Democratic Republic ofAmerican SamoaAndorra, Principality ofAngola, Republic ofAnguillaAntarctica (the territory South of 60 deg S)Antigua and BarbudaArgentina, Argentine RepublicArmeniaArubaAustralia, Commonwealth ofAustria, Republic ofAzerbaijan, Republic ofBahrain, Kingdom ofBangladesh, People’s Republic ofBarbadosBelarusBelgium, Kingdom ofBelizeBenin, People’s Republic ofBermudaBhutan, Kingdom ofBolivia, Republic ofBosnia and HerzegovinaBotswana, Republic ofBouvet Island (Bouvetoya)Brazil, Federative Republic ofBritish Indian Ocean Territory (Chagos Archipelago)British Virgin IslandsBrunei DarussalamBulgaria, People’s Republic ofBurkina FasoBurundi, Republic ofCambodia, Kingdom ofCameroon, United Republic ofCape Verde, Republic ofCayman IslandsCentral African RepublicChad, Republic ofChile, Republic ofChina, People’s Republic ofChristmas IslandCocos (Keeling) IslandsColombia, Republic ofComoros, Union of theCongo, Democratic Republic ofCongo, People’s Republic ofCook IslandsCosta Rica, Republic ofCote D’Ivoire, Ivory Coast, Republic of theCyprus, Republic ofCzech RepublicDenmark, Kingdom ofDjibouti, Republic ofDominica, Commonwealth ofEcuador, Republic ofEgypt, Arab Republic ofEl Salvador, Republic ofEquatorial Guinea, Republic ofEritreaEstoniaEthiopiaFaeroe IslandsFalkland Islands (Malvinas)Fiji, Republic of the Fiji IslandsFinland, Republic ofFrance, French RepublicFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabon, Gabonese RepublicGambia, Republic of theGeorgiaGermanyGhana, Republic ofGibraltarGreece, Hellenic RepublicGreenlandGrenadaGuadaloupeGuamGuatemala, Republic ofGuinea, Revolutionary
People’s Rep’c ofGuinea-Bissau, Republic ofGuyana, Republic ofHeard and McDonald IslandsHoly See (Vatican City State)Honduras, Republic ofHong Kong, Special Administrative Region of ChinaHrvatska (Croatia)Hungary, Hungarian People’s RepublicIceland, Republic ofIndia, Republic ofIndonesia, Republic ofIran, Islamic Republic ofIraq, Republic ofIrelandIsrael, State ofItaly, Italian RepublicJapanJordan, Hashemite Kingdom ofKazakhstan, Republic ofKenya, Republic ofKiribati, Republic ofKorea, Democratic People’s Republic ofKorea, Republic ofKuwait, State ofKyrgyz RepublicLao People’s Democratic RepublicLatviaLebanon, Lebanese RepublicLesotho, Kingdom ofLiberia, Republic ofLibyan Arab JamahiriyaLiechtenstein, Principality ofLithuaniaLuxembourg, Grand Duchy ofMacao, Special Administrative Region of ChinaMacedonia, the former Yugoslav Republic ofMadagascar, Republic ofMalawi, Republic ofMalaysiaMaldives, Republic ofMali, Republic ofMalta, Republic ofMarshall IslandsMartiniqueMauritania, Islamic Republic ofMauritiusMayotteMicronesia, Federated States ofMoldova, Republic ofMonaco, Principality ofMongolia, Mongolian People’s RepublicMontserratMorocco, Kingdom ofMozambique, People’s Republic ofMyanmarNamibiaNauru, Republic ofNepal, Kingdom ofNetherlands AntillesNetherlands, Kingdom of theNew CaledoniaNew ZealandNicaragua, Republic ofNiger, Republic of theNigeria, Federal Republic ofNiue, Republic ofNorfolk IslandNorthern Mariana IslandsNorway, Kingdom ofOman, Sultanate ofPakistan, Islamic Republic ofPalauPalestinian Territory, OccupiedPanama, Republic ofPapua New GuineaParaguay, Republic ofPeru, Republic ofPhilippines, Republic of thePitcairn IslandPoland, Polish People’s RepublicPortugal, Portuguese RepublicPuerto RicoQatar, State ofReunionRomania, Socialist Republic ofRussian FederationRwanda, Rwandese RepublicSamoa, Independent State ofSan Marino, Republic ofSao Tome and Principe, Democratic Republic ofSaudi Arabia, Kingdom ofSenegal, Republic ofSerbia and MontenegroSeychelles, Republic ofSierra Leone, Republic ofSingapore, Republic ofSlovakia (Slovak Republic)SloveniaSolomon IslandsSomalia, Somali RepublicSouth Africa, Republic ofSouth Georgia and the South Sandwich IslandsSpain, Spanish StateSri Lanka, Democratic Socialist Republic ofSt. HelenaSt. Kitts and NevisSt. LuciaSt. Pierre and MiquelonSt. Vincent and the GrenadinesSudan, Democratic Republic of theSuriname, Republic ofSvalbard & Jan Mayen IslandsSwaziland, Kingdom ofSweden, Kingdom ofSwitzerland, Swiss ConfederationSyrian Arab RepublicTaiwan, Province of ChinaTajikistanTanzania, United Republic ofThailand, Kingdom ofTimor-Leste, Democratic Republic ofTogo, Togolese RepublicTokelau (Tokelau Islands)Tonga, Kingdom ofTrinidad and Tobago, Republic ofTunisia, Republic ofTurkey, Republic ofTurkmenistanTurks and Caicos IslandsTuvaluUganda, Republic ofUkraineUnited Arab EmiratesUnited Kingdom of Great Britain & N. IrelandUruguay, Eastern Republic ofUzbekistanVanuatuVenezuela, Bolivarian Republic ofViet Nam, Socialist Republic ofWallis and Futuna IslandsWestern SaharaYemenZambia, Republic ofZimbabwe

It’s another prime time NFL game, which means the Chiefs are playing. That’s what happens when a team has appeared in five of the past six Super Bowls and now has a player dating the most famous singer in the world.

Tonight, Patrick Mahomes, Travis Kelce and company host the Washington Commanders. Soon enough, bettors in Missouri will be legal wagering on a Chiefs primetime game.

Missouri sports betting is set to launch at 12:00 am CT on December 1. The Monday Night Football game that day is Patriots vs. Giants, but the following Sunday the Chiefs host the Texans on Sunday Night Football.

Bettors who are 21+ in Missouri don’t need to wait to get a demo of the DraftKings Missouri app. Just click below and take it for a test run. You won’t be able to deposit or wager until 12:00 am CT on December 1, but you’ll get to see why bettors in 39 states love DraftKings.

Missouri online sports betting overview

The Missouri Gaming Commission recently approved temporary sports betting licenses for nine sportsbooks looking to start taking bets at 12:00 am CT on December 1. Pre-registration can start on Nov. 17 at 12:00 CT. Let’s take a look at the players in Missouri:

The two names that standout the most on this list are Circa and Underdog. Circa scored a massive upset when it was awarded an “untethered” license over FanDuel in August.

What that means is neither DraftKings, nor Circa need partners to launch in Missouri (hence they can keep all the profits for themselves).

DraftKings and FanDuel poured in more than $40 into the ballot initiative that paved the way to legalize Missouri sports betting, so it was eye-brow raising that it did not prevail over Circa.

FanDuel quickly recovered from the sting of losing out to Circa by partnering with St. Louis CITY SC of the MLS.

Underdog, meanwhile, was one of the first to apply for a license in Missouri. The DFS and now sports betting operator has partnered with the Kansas City Royals.

BetMGM partnered with Century Casinos and Fanatics is launching through a deal with Boyd Gaming. Two other future Missouri sportsbook operators, Caesars and ESPN BET, do not need a partner because both have land-based casino interests in the state.

Missouri sports betting pro teams have ‘skin’ in the game

One of the biggest reasons Amendment 2 passed can be attributed to the groundswell of support from Missouri’s pro sports teams. As a result, six pro teams have sports betting licenses. Here’s a look at those partnerships:

• St. Louis Cardinals (bet365)
• Kansas City Royals (Underdog)
• St. Louis CITY SC of MLS (FanDuel)
• Kansas City Chiefs (BetMGM, existing from Kansas launch)
• St. Louis Blues (Underdog)
• Kansas City Current of NWSL (TBD)

There can be up to 19 retail sports betting licenses (stadiums, casinos). A few casino/sportsbook partnerships have already been established. Here’s a brief overview of those:

Where to bet in person in Missouri on December 1

• Horseshoe St. Louis: Caesars Sportsbook
• Harrah’s Kansas City: Caesars Sportsbook
• Isle of Capri Casino Boonville: Caesars Sportsbook
• Hollywood Casino St. Louis: ESPN BET
• Argosy Riverside Casino: ESPN BET
• River City Casino: ESPN BET
• Century Casino Cape Girardeau: BetMGM
• Ameristar Casino Kansas City: Fanatics Sportsbook

The six pro teams with licenses can also have a retail sportsbook in or around their stadiums.

Learn more about our gaming editorial staff.

If you or a loved one has questions and needs to talk to a professional about gambling, call the Ohio Problem Gambling Helpline at 1-800-589-9966 or the National Council on Program Gambling Helpline (NCPG) at 1-800-522-4700 or visit 1800gambler.net for more information. 21+ and present in Ohio. Gambling problem? Call 1-800-Gambler.