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March Madness picks: Predictions, schedule, odds, lines for South region; Michigan trying to avoid 5-vs.-12 upset

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March Madness picks: Predictions, schedule, odds, lines for South region; Michigan trying to avoid 5-vs.-12 upset


The stat was making the rounds after Auburn didn’t make the championship game of the SEC tournament: No team has lost three of its past four games before the NCAA tournament and won a national championship.

And yet, Auburn still was a somewhat surprising pick as the No. 1 overall seed in the tournament.

Auburn stumbled late in a very tough league, which might open things up for the other teams in the South region. Auburn will open the tournament against Alabama State, which took down St. Francis 70-68 on a thrilling final-second layup off a tipped full-court pass in the First Four at Dayton on Tuesday. (We’re also waiting to see if San Diego State or North Carolina play Ole Miss on Friday, as well), but here are the rest of the picks for the first round in the South, with all the odds from BetMGM:

Midwest region picks | East region picks | West region picks

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(All times Eastern.)

The first game of the first round Thursday is a good one. Louisville seems very under-seeded, but that’s part of playing in a bad ACC. Still, since Dec. 14 the Cardinals are 21-2 and one of the losses came to Duke in the ACC tournament. Creighton has been a very good team too, and 7-foot-1 Ryan Kalkbrenner will be a problem for the Cardinals. But I won’t hold it against Louisville that the ACC was down. The Cards advance.

Alabama State thrilled us with a great NCAA tournament opener, with a last-second shot to win it. But this isn’t the type of 16 seed that can scare a 1 seed. Alabama State doesn’t have any strength that will keep it in a game against an Auburn team looking to quiet critics who wondered how it got the No. 1 overall seed after losing three of their last four.

[Full NCAA tournament bracket revealed | Printable bracket]

Yale has become the Ivy’s best program, and this season it dominated the league. Yale was 16-1 after Dec. 22. Texas A&M is a good team, but it lives off offensive rebounding (the best offensive rebounding percentage in the nation), and yet Yale is pretty good on the defensive boards. The Ivy League has been pretty good in the first round of the NCAA tournament, going 10-4 against the spread in the first round since 2009 (per Matt Eisenberg’s Tournament Guide). Texas A&M could make a run into the second weekend, but this one isn’t going to be easy.

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Vladislav Goldin helped lead the Michigan Wolverines to a Big Ten tournament championship. (Photo by Aaron J. Thornton/Getty Images)

Vladislav Goldin helped lead the Michigan Wolverines to a Big Ten tournament championship. (Photo by Aaron J. Thornton/Getty Images)

Ah, the 5 vs. 12 game. We all know by now this is where upsets come from, and UC San Diego is a dangerous 12 seed. KenPom.com had San Diego as the 36th best team in the sport, which is rarified air for a Big West school. That’s just one spot below UConn, the reigning champs. San Diego does everything well, and it shoots (and hits) a lot of 3s. The problem is UCSD’s size. It doesn’t have a regular who is taller than 6-8. Michigan is the rare team with two 7-footers, Vladislav Goldin and Danny Wolf. If UCSD hits a ton of 3s this could be a fun upset, but this was a really unfortunate matchup for a strong mid-major.

[Yahoo Fantasy Bracket Mayhem is back: Enter for a shot to win up to $50K]

Iowa State looked like it could be a Final Four contender, but the last month was a little rough. Injuries affected the Cyclones. It appears Tamin Lipsey (10.8 ppg) will return from injury, but Keshon Gilbert (13.4 ppg) is out for the season via the Des Moines Register. That lowers the Cyclones’ ceiling. Lipscomb has a lot of shooters, which is what you want from a big underdog. If Lipscomb can knock down some of the many 3s it’s going to take, this one could be interesting late.

Most years, a team that wins in the First Four also wins a first-round game. This isn’t just an overreaction to UNC’s dominant win over San Diego State; the Tar Heels match up pretty well with Ole Miss. UNC didn’t deserve an at-large spot but that never meant it couldn’t get hot and win multiple games.

If you like guard play, this will be a fun matchup. Marquette’s Kam Jones is one of the best players in the country, a Bob Cousy Award finalist for the trophy that goes to the nation’s best point guard. New Mexico’s Donovan Dent and his 20.6 points per game should get more respect for postseason honors. Marquette won just five of its last 12 games, but there weren’t any bad losses. This isn’t an easy pick between two similar but flawed teams. Marquette might be happy to not see a Big East foe.

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Michigan State had a tremendous season. The Spartans were good to bettors too, posting a 22-10-1 mark against the spread via Action Network, one of the best marks in the sport. MSU won’t shoot many 3s, won’t shoot them well, but can score inside and rebound it well. Bryant is one of the few 15 seeds that actually has some decent size. It has the sixth-tallest team in college basketball, according to KenPom.com. The Bulldogs didn’t play a tough schedule and against the two best teams they played, St. John’s and Grand Canyon, they lost by 22 and 46, respectively. There’s no upset concern here, but Bryant might not be a total pushover.



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How MSU’s deer vaccine capsules could curb black-legged ticks in Michigan

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How MSU’s deer vaccine capsules could curb black-legged ticks in Michigan


EAST LANSING, Mich. – Black-legged ticks have been increasing across Michigan this summer, raising concerns about tick-borne illnesses like Lyme disease.

—> Michigan health officials alarmed by surge in Lyme disease cases

Researchers at Michigan State University say the large white-tailed deer population plays a key role in spreading these ticks.

To address the problem, MSU scientists are testing food capsules containing biomarkers to see if deer will eat them.

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Each capsule currently includes corn, alfalfa, molasses, and a biomarker that helps track how many deer consume the capsules.

If successful, the capsules will eventually contain a vaccine to help deer build immunity to ticks, similar to how dogs are vaccinated.

The goal is to reduce the number of ticks on deer, which could lower the risk of tick-borne diseases for people spending time outdoors.

MSU professors describe this as an innovative method that could be a game-changer for controlling black-legged ticks and Lyme disease in Michigan. The capsules are being introduced in selected parks and land preserves in the Mid-Michigan area as part of the early phase of this research.

In the future, the team plans to add a drug or vaccine to the capsules to eliminate ticks on deer, aiming to stop the problem at its source.

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—> 4 ways to protect yourself from ticks in Michigan, and 4 things to do after you’re outside

Copyright 2025 by WDIV ClickOnDetroit – All rights reserved.



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Trump administration renews push to fire Fed governor from Michigan ahead of key vote

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Trump administration renews push to fire Fed governor from Michigan ahead of key vote


President Donald Trump’s administration renewed its request Sunday for a federal appeals court to let him fire Lisa Cook from the Federal Reserve’s board of governors, a move the president is seeking ahead of the central bank’s vote on interest rates.

The Trump administration filed a response just ahead of a 3 p.m. Eastern deadline Sunday to the U.S. Court of Appeals for the District of Columbia, arguing that Cook’s legal arguments for why she should stay on the job were meritless. Lawyers for Cook argued in a Saturday filing that the Trump administration has not shown sufficient cause to fire her, and stressed the risks to the economy and country if the president were allowed to fire a Fed governor without proper cause.

Sunday’s filing is the latest step in an unprecedented effort by the White House to shape the historically independent Fed. Cook’s firing marks the first time in the central bank’s 112-year history that a president has tried to fire a governor.

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“The public and the executive share an interest in ensuring the integrity of the Federal Reserve,” Trump’s lawyers argued in Sunday’s filing. “And that requires respecting the president’s statutory authority to remove governors ‘for cause’ when such cause arises.”

Bill Pulte, a Trump appointee to the agency that regulates mortgage giants Fannie Mae and Freddie Mac, has accused Cook of signing separate documents in which she allegedly said that both the Atlanta property and a home in Ann Arbor, Michigan, also purchased in June 2021, were both “primary residences.” Pulte submitted a criminal referral to the Justice Department, which has opened an investigation.

Trump relied on those allegations to fire Cook “for cause.”

Cook, the first Black woman to serve as a Fed governor, referred to the condominium as a “vacation home” in a loan estimate, a characterization that could undermine claims by the Trump administration that she committed mortgage fraud. Documents obtained by The Associated Press also showed that on a second form submitted by Cook to gain a security clearance, she described the property as a “second home.”

Cook sued the Trump administration to block her firing and a federal judge ruled Tuesday that the removal was illegal and reinstated her to the Fed’s board.

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The administration appealed and asked for an emergency ruling just before the Fed is set to meet this week and decide whether to reduce its key interest rate. Most economists expect they will cut the rate by a quarter point.



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Michigan football vs. Central Michigan: Live updates, score, injuries

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Michigan football vs. Central Michigan: Live updates, score, injuries


It’s an in-state matchup on Saturday, Sept. 13, as Michigan football (1-1) takes on the Central Michigan Chippewas (1-1) for the Wolverines’ second home game of the season.

After a loss on the road at Oklahoma last week in which Michigan struggled to generate offense, the Wolverines — and particularly freshman quarterback Bryce Underwood — are looking to sharpen their offensive skills against a weaker Chippewas.

They’ll have to do so without coach Sherrone Moore, however. The coach is serving the first of a two-game suspension sanctioned by the school for his role in the Connor Stalions sign-stealing scandal. In the interim, Biff Poggi will lead the Wolverines.

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Michigan’s task will be to hone its skills on both sides of the ball, but with an emphasis on offense. The Wolverines struggled to run the ball last week and Underwood had difficulty connecting with receivers downfield as well. Central Michigan provides a perfect opportunity for Michigan to build its offensive cohesiveness before beginning Big Ten play.

Follow along below for live updates.

Michigan football vs. Central Michigan early availability report

Michigan – Out: QB Davis Warren (knee), OT Andrew Babalola (knee). Probable: DB Rod Moore (knee), DB Shamari Earls (undisclosed), DB Caleb Anderson (undisclosed). Questionable: TE Marlin Klein (right foot/ankle), DB Zeke Berry (lower body), RB John Volker (undisclosed), LB Jaydon Hood (undisclosed), RB Bryson Kuzdzal (undisclosed), RB Donovan Johnson (undisclosed), edge Devon Baxter, DT Ike Iwunnah (undisclosed), WR C.J. Charleston (undisclosed). Doubtful: OL Gio-EL Hadi (left ankle/foot)

Central Michigan – Missed Week 2: TE Rory Callahan, OL John Iannuzzi.

Matchup: No. 22 Michigan (1-1) vs. Central Michigan (1-1)

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Kickoff: Noon Saturday, Sept. 13; Michigan Stadium, Ann Arbor.

TV/radio: Big Ten Network; WCSX-FM (94.7).Looking for a free mini puzzle? Play the USA TODAY Quick Cross now.

Line: Wolverines by 27½.

Michigan football schedule 2025

Week 1: W, 34-17 vs New Mexico.

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Week 2: L, 13-24 at Oklahoma

Week 3: vs Central Michigan, Saturday Sept. 13, noon ET (Big Ten Network).

Week 4: at Nebraska, Saturday Sept. 20, 3:30 p.m. ET (CBS).

Week 5: BYE.

Week 6: vs Wisconsin, Saturday Oct. 4, 12 p.m. or 3:30 p.m.

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Week 7: at USC, Saturday Oct. 11, time TBD.

Week 8: vs Washington, Saturday Oct. 18, time TBD.

Week 9: at Michigan State, Saturday Oct. 25, time TBD.

Week 10: vs Purdue, Sautrday Nov. 1, time TBD.

Week 11: BYE.

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Week 12: at Northwestern, Saturday Nov. 15, time TBD.

Week 13: at Maryland, Saturday Nov. 22, time TBD.

Week 14: vs Ohio State, Saturday Nov. 29, noon ET (Fox).

Contact Matthew Auchincloss at mauchincloss@freepress.com.

Our team of savvy editors independently handpicks all recommendations. If you purchase through our links, the USA Today Network may earn a commission. Prices were accurate at the time of publication but may change.

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