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Purdue vs Indiana Prediction: Odds, Expert Picks, QB Matchup, Betting Trends and Stats

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Purdue vs Indiana Prediction: Odds, Expert Picks, QB Matchup, Betting Trends and Stats


Indiana is coming off its first loss of the season and welcomes Purdue to town for Senior Day.

The Indiana Hoosiers are 10-1 with its first loss of the season coming at Ohio State (38-15). Indiana dropped to No. 10 in the AP Poll and will likely be on the backend of the teams in for the latest College Football Playoff rankings, but a convincing win here would help. Indiana has been one of the best against-the-spread (ATS) teams in the country and as a -29 point home favorite, all signs point to Curt Cignetti and company rolling.

Not much has gone right for the 1-10 Purdue Boilermakers. After the 49-0 win over FCS Indiana State, Purdue has lost 10 straight games with seven out of 10 losses coming by 17 or more points. Purdue lost to Michigan State 24-17 last week and has two OT losses this year, but this road game seems out of reach for the Boilermakers.

NBC Sports has all the latest info and analysis you need, including how to tune in for kickoff, odds from BetMGM, player news and updates, and of course our predictions and best bets for the game from our staff of experts.

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Listen to the B1G Talk podcast with Todd Blackledge and Noah Eagle for the most compelling storylines across all ofcollege football, with the biggest teams on the rise and the latest rankings!

Game Details and How to watch Purdue @ Indiana

  • Date: Saturday, November 30, 2024
  • Time: 7:00 PM EST
  • Site: Indiana University Memorial Stadium
  • City: Bloomington, IN
  • TV/Streaming: Fox Sports 1

Want to check out the other games on the College Football schedule this week? We’ve got you covered right here on NBC Sports with all the matchup, venue, game-time and TV/streaming info so you won’t miss any of the action!

Game odds for Purdue @ Indiana

The latest odds as of Tuesday afternoon:

o Moneyline: Indiana (-6500), Purdue (+2000)

o Spread: Indiana -29 (-110)

o Total: 56.5 points

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*odds courtesy of BetMGM

The spread opened at Indiana -25.5, so heavy money is pouring in on the Hoosiers. That is no surprise since Indiana is on the cusp of a College Football Playoff. The total has no movement.

NBC Sports Bet Best Bet

Vaughn Dalzell (@VmoneySports) has the following best bets between Purdue and Indiana:

“The Indiana Hoosiers suffered the first loss of the season last week at Ohio State (38-15) and need to bounce back dominantly to secure a College Football Playoff berth.

Indiana’s First Half Team Total is 23.5, which might seem mighty lofty, but it’s certainly within range and so is a 50-point game for the Hoosiers. At home, Indiana has scored 17, 17, 14, 31, and 21 first-half points versus DI opponents this season for 20.0 first-half points per game.

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Purdue’s defense hasn’t taken any steps forward this season. In the last seven games, the Boilermakers have allowed 24, 21, 21, 17, 21, 24, and 21 first-half points, so this number is nothing Indiana cannot do.”

BetMGM College Football Insights: National Championship

Line movement (Last Week to Now)

  • Ohio State +320 to +275
  • Georgia +500 to +400
  • Texas +500 to +450

Highest Ticket%

  • Ohio State 13.4%
  • Texas 11.1%
  • Georgia 10.5%

Highest Handle%

  • Ohio State 15.9%
  • Georgia 14.9%
  • Alabama 12.1%

Biggest Liabilities

  • Colorado
  • Ohio State
  • Alabama

College Football talk is taking over Bet the Edge every Thursday throughout the season. Bet the EDGE is your source for all things sports betting. Get all of Vaughn Dalzell, Eric Froton, and Brad Thomas’ insights Thursdays at 6AM ET right here or wherever you get your favorite podcasts.

Quarterback matchup for Boilermakers @ Hoosiers

  • Purdue: Hudson Card threw for a season-high 342 passing yards against Michigan State last week on 26-of-47. Card has nine touchdowns to six interceptions on the year and 1,606 passing yards.
  • Indiana: Kurtis Rourke has had a phenomenal season that has begun to be derailed slightly by injury. Rourke has 274 combined passing yards in the past two games and had zero touchdowns to zero interceptions last week. On the season, Rourke has 21 touchdowns to four interceptions for 2,478 passing yards and a 69.6 completion percentage.

Boilermakers @ Hoosiers player news & recent stats

  • Purdue is 3-8 ATS this season, ranking tied for fifth-worst.
  • Indiana is 8-3 ATS this season, ranking tied for seventh-best.
  • Indiana is 8-3 to the Over this season, ranking third-best.
  • Indiana is 5-2 ATS this year at home and 4-3 to the Over.
  • Purdue is 2-3 ATS this season as the road team and 3-2 to the Over.
  • Kurtis Rouke threw for zero touchdowns and zero interceptions last week.
  • Hudson Card threw a season-high 342 passing yards last week.

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Follow our experts on socials to keep up with all the latest content from the staff:

  • Vaughn Dalzell (@VmoneySports)
  • Brad Thomas (@MrBradThomas)
  • Drew Dinsick (@whale_capper)
  • Jay Croucher (@croucherJD)
  • Eric Froton (@CFFroton)





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Indiana law enforcement takes up donations for Special Olympics

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Indiana law enforcement takes up donations for Special Olympics


FORT WAYNE, Ind. (WANE) — More than 50 Indiana law enforcement agencies are taking to the roof to help local athletes. 

Police and safety officers will be stationed around various Dunkin’ Donuts, taking up donations for the Special Olympics. People who monetarily donate will receive a coupon for a free donut. Those who donate $10 or more will receive a coupon for a free medium hot coffee. 

“Supporting the Special Olympics isn’t just an event for us — it’s a commitment to people who inspire us every day,” Sergeant Wes Rowlader said. “These athletes show what determination, courage, and community truly look like. Every dollar we raise helps transform that spirit into training, competition, and lifelong confidence.” 

More than 20,000 Hoosier athletes train and compete for free within the Special Olympics. To date, Cop on a Rooftop has raised more than $125,000 for Special Olympics Indiana. 

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The Indiana State Police will be at the Dunkin’ Donuts at 9821 Lima Road in Fort Wayne from 5 a.m. to 12 p.m. on Friday.



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Man shot by security guard in hospital emergency room waiting area in Gary, Indiana

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Man shot by security guard in hospital emergency room waiting area in Gary, Indiana


A man’s family is demanding answers after he was shot by a security guard inside a hospital emergency room waiting area on Tuesday night in Gary, Indiana.

Methodist Northlake Hospital officials said, around midnight Tuesday night, its security staff responded quickly after a patient took out a gun. The hospital said he’d threatened to shoot himself or others.

The hospital commended the security guard who shot the man for “neutralizing the threat and helping ensure the safety of our patients and employees.”

Family members identified the man who was shot as Otis Brown. They said he is a kind father to a 12-year-old boy.

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“Just a great person, a happy-go-lucky, always out there trying to do the right thing,” said his fiancée, Stacey Taylor.

Taylor said she was on a business trip when she got a call that Brown had been shot multiple times.

“Scared, uncertainty; you know, what story is right? You know, what happened?” she said.

After he was shot, Brown was taken to University of Chicago Medical Center for treatment.

Taylor said she had no idea why Brown went to Methodist Northlake Hospital in the first place. His family said he was trying to leave the hospital when the shooting happened, claiming that the hospital gave him his gun back after he was cleared to leave.

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“We just want to get answers, just want to know what happened, particularly when people are defaming his name,” Taylor said.

She and Brown’s family hope the hospital has surveillance video footage that can help provide answers.

Gary police have not provided any details on the shooting. The Lake County Sheriff’s Department said it is investigating the shooting at the request of Gary police, but did not provide any further information.



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Indiana A.G. finishes Karl King Tower investigation, finalizes compliance order

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Indiana A.G. finishes Karl King Tower investigation, finalizes compliance order


The Indiana Attorney General has finished its investigation into Karl King Tower and issued a compliance order.

This is coming after a months-long investigation into the unsafe living conditions for residents at the apartments.

From December 2025 to January 2026, there were prolonged failures with the heating and a lack of heat for residents during winter conditions at Karl King.

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The property owner provided a 20% rent credit for affected tenants and documentation related to health and safety issues.

Below is the agreement from the Attorney General:

  • The owner must complete boiler and heating system improvements by September 30.
  • The property is subject to a monitoring period for multiple years.
  • The owner needs to provide on-site security, including cameras in common areas and monthly incident reports.
  • The building needs an on-site property manager to address resident concerns.
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The Attorney General has the authority to inspect the property and enforce compliance if commitments aren’t met.



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