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Ohio State vs. Indiana football picks: What the oddsmakers say

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Ohio State vs. Indiana football picks: What the oddsmakers say


A huge battle between top-five ranked Big Ten teams kicks off as No. 2 Ohio State welcomes No. 5 Indiana on Saturday. Here’s how the oddsmakers are predicting the game right now.

Ohio State moved to 6-1 in Big Ten play but still sits in third place in the standings thanks to that 1-point loss at Oregon earlier this year, and this game will determine second place in the league.

Standing in the Buckeyes’ way is arguably the surprise team in college football this season: undefeated Indiana, playing its first-ever 10-win season behind the nation’s second-ranked scoring offense under first-year head coach Curt Cignetti.

What do the wiseguys expect will happen as the Buckeyes host the Hoosiers this weekend?

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Let’s check in with the early predictions for Ohio State vs. Indiana in this Week 12 college football game, according to the oddsmakers.

Ohio State is an 11.5 point favorite against Indiana, according to the lines at FanDuel Sportsbook.

The book lists the total at 52.5 points for the game.

And it set the moneyline odds for Ohio State at -465 and for Indiana at +350 to win outright.

Ohio State: -11.5 (-110)
Indiana: +11.5 (-110)

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Over 52.5 points: -104
Under 52.5 points: -118

Ohio State is 5-5 against the spread (50%) overall so far this season …

Indiana is 8-2 (80%) ATS in ‘24, the third-best mark nationally …

Ohio State is 3-3 against the spread at home this year …

Indiana is 3-0 ATS on the road …

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The total went under in 6 of Ohio State’s last 7 games …

Indiana is 5-0 ATS in its last 5 games on the road …

Ohio State is 8-4 against the spread in its last 12 home games …

Indiana is 6-1 ATS in its last 7 games on the road against Ohio State …

Ohio State is 4-2 against the spread in its last 6 games in November …

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The total went over in 7 of Indiana’s last 9 games …

A plurality of bettors expect the Hoosiers to give the Buckeyes a good scare this weekend, according to the spread consensus picks for the game.

Indiana is getting 66 percent of bets to either win outright in an upset, or to keep the margin under a dozen points in a loss.

The other 44 percent of wagers project Ohio State will win the game and cover the big spread.

The game’s implied score suggests a comfortable win for the Buckeyes against the Hoosiers.

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When taking the point spread and total into consideration, it’s implied that Ohio State will defeat Indiana by a projected score of 32 to 21.

Our early pick: Indiana +11.5 … Ohio State hasn’t performed well against the spread and its defense has been prone to exposure by aggressive passing offenses. Buckeyes by 10.

When: Sat., Nov. 23
Time: 12 p.m. Eastern
TV: Fox network

Game odds refresh periodically and are subject to change.

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If you or someone you know has a gambling problem and wants help, please call 1-800-GAMBLER.

More college football from SI: Top 25 Rankings | Schedule | Teams

Follow College Football HQ: Bookmark | Rankings | Picks



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Indiana

Indiana law enforcement takes up donations for Special Olympics

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Indiana law enforcement takes up donations for Special Olympics


FORT WAYNE, Ind. (WANE) — More than 50 Indiana law enforcement agencies are taking to the roof to help local athletes. 

Police and safety officers will be stationed around various Dunkin’ Donuts, taking up donations for the Special Olympics. People who monetarily donate will receive a coupon for a free donut. Those who donate $10 or more will receive a coupon for a free medium hot coffee. 

“Supporting the Special Olympics isn’t just an event for us — it’s a commitment to people who inspire us every day,” Sergeant Wes Rowlader said. “These athletes show what determination, courage, and community truly look like. Every dollar we raise helps transform that spirit into training, competition, and lifelong confidence.” 

More than 20,000 Hoosier athletes train and compete for free within the Special Olympics. To date, Cop on a Rooftop has raised more than $125,000 for Special Olympics Indiana. 

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The Indiana State Police will be at the Dunkin’ Donuts at 9821 Lima Road in Fort Wayne from 5 a.m. to 12 p.m. on Friday.



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Man shot by security guard in hospital emergency room waiting area in Gary, Indiana

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Man shot by security guard in hospital emergency room waiting area in Gary, Indiana


A man’s family is demanding answers after he was shot by a security guard inside a hospital emergency room waiting area on Tuesday night in Gary, Indiana.

Methodist Northlake Hospital officials said, around midnight Tuesday night, its security staff responded quickly after a patient took out a gun. The hospital said he’d threatened to shoot himself or others.

The hospital commended the security guard who shot the man for “neutralizing the threat and helping ensure the safety of our patients and employees.”

Family members identified the man who was shot as Otis Brown. They said he is a kind father to a 12-year-old boy.

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“Just a great person, a happy-go-lucky, always out there trying to do the right thing,” said his fiancée, Stacey Taylor.

Taylor said she was on a business trip when she got a call that Brown had been shot multiple times.

“Scared, uncertainty; you know, what story is right? You know, what happened?” she said.

After he was shot, Brown was taken to University of Chicago Medical Center for treatment.

Taylor said she had no idea why Brown went to Methodist Northlake Hospital in the first place. His family said he was trying to leave the hospital when the shooting happened, claiming that the hospital gave him his gun back after he was cleared to leave.

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“We just want to get answers, just want to know what happened, particularly when people are defaming his name,” Taylor said.

She and Brown’s family hope the hospital has surveillance video footage that can help provide answers.

Gary police have not provided any details on the shooting. The Lake County Sheriff’s Department said it is investigating the shooting at the request of Gary police, but did not provide any further information.



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Indiana A.G. finishes Karl King Tower investigation, finalizes compliance order

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Indiana A.G. finishes Karl King Tower investigation, finalizes compliance order


The Indiana Attorney General has finished its investigation into Karl King Tower and issued a compliance order.

This is coming after a months-long investigation into the unsafe living conditions for residents at the apartments.

From December 2025 to January 2026, there were prolonged failures with the heating and a lack of heat for residents during winter conditions at Karl King.

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The property owner provided a 20% rent credit for affected tenants and documentation related to health and safety issues.

Below is the agreement from the Attorney General:

  • The owner must complete boiler and heating system improvements by September 30.
  • The property is subject to a monitoring period for multiple years.
  • The owner needs to provide on-site security, including cameras in common areas and monthly incident reports.
  • The building needs an on-site property manager to address resident concerns.
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The Attorney General has the authority to inspect the property and enforce compliance if commitments aren’t met.



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