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Toxic people in your life may have a hidden health impact, study suggests

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Toxic people in your life may have a hidden health impact, study suggests

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Surrounding yourself with difficult people could shorten your lifespan, according to new research.

A study published in the journal PNAS found that negative social ties contribute to a faster aging pace and an older biological age.

The researchers, from various U.S.-based universities, studied how “hasslers,” or people who often cause problems or social difficulties, impacted aging and mortality, according to a study press release.

NEW STUDY HINTS AT A HIDDEN ALZHEIMER’S RISK FACTOR AFFECTING OLDER AMERICANS

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Biological aging refers to the pace of aging on a cellular level, which is often different from chronological age.

Based on a sample of more than 2,000 Indiana participants 18 years and older, nearly 30% of individuals reported having a “hassler” in their network.

The study suggests that negative relationships can act like chronic stressors that wear the body down over time. (iStock)

People who were more likely to report hasslers included women, daily smokers, people in worse health and those with adverse childhood experiences.

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Using biological clocks that measure age-related changes to DNA, the researchers found that the presence of hasslers was linked to accelerated aging, higher inflammation, more chronic conditions and worse mental health.

For each additional hassler, there was about a 1.5% increased pace of aging and about a nine-month older biological age.

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Not all hasslers “exert the same influence,” as blood relatives and non-blood relatives both showed “detrimental” associations, but spouse hasslers do not, the researchers stated.

Blood-related hasslers are hard to avoid, making them “stronger chronic stressors,” according to the study. Spouse hasslers may not have shown a significant association because these ties mix negative and positive exchanges. 

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Kin and non-kin relationships were more “detrimental” to health than spouse relationships, the study found. (iStock)

“These findings together highlight the critical role of negative social ties in biological aging as chronic stressors, and the need for interventions that reduce harmful social exposures to promote healthier aging trajectories,” the researchers wrote in the study abstract.

“We are surrounded by those who make our lives difficult and cause problems,” study co-author Byungkyu Lee of NYU’s Department of Sociology told Fox News Digital.

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“We found that they are not just stressful; they are associated with measurable acceleration in biological aging at the molecular level, along with higher inflammation, depression, anxiety and chronic disease burden.”

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“Our results suggest that the overall balance of one’s social network matters.”

Reducing exposure to people who consistently create stress or conflict “may benefit health,” the study suggests, although this is not always realistic, Lee noted.

“Many of these relationships involve family members or others who are deeply embedded in daily life, so the challenge is often not simply avoiding them, but finding healthier ways to manage them,” he said. “More broadly, our results suggest that the overall balance of one’s social network matters.”

“Many of these relationships involve family members or others who are deeply embedded in daily life, so the challenge is often not simply avoiding them, but finding healthier ways to manage them,” said the researcher. (iStock)

Community-based programs that expand social circles through shared hobbies, volunteering or mutual aid may be beneficial, the researchers suggested.

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“Broadening and diversifying one’s network may be one way to offset some of the biological toll associated with chronic relationship stress,” Lee added.

Study limitations

The authors noted that these findings only show an association, but do not prove that toxic relationships have a negative impact on aging. Other traits or environments were not considered when measuring morbidity.

Because the data came from one Midwestern sample, it may not apply to other cultural or socioeconomic populations.

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The study used data collected at one point in time, which means it cannot show whether hasslers came before the aging changes or if the faster aging influenced social perceptions.

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The hassler relationships were also self-reported and subject to participants’ moods and experiences — which could introduce some bias.

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Video: How Profit-Seeking Autism Clinics Can Harm Kids

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Video: How Profit-Seeking Autism Clinics Can Harm Kids

new video loaded: How Profit-Seeking Autism Clinics Can Harm Kids

Profit motives are shaping the care inside an expanding autism therapy industry, creating conditions that can harm some children. Our health reporter Sarah Kliff explains her new investigation, co-authored with Margot Sanger-Katz.

By Sarah Kliff, Margot Sanger-Katz, Erin Schaff, Paul Abowd, Jon Miller and Whitney Shefte

May 23, 2026

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How pneumonia progresses to sepsis: Doctors explain after Kyle Busch’s death

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How pneumonia progresses to sepsis: Doctors explain after Kyle Busch’s death

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NASCAR star Kyle Busch’s cause of death was revealed Saturday as severe pneumonia that progressed into sepsis, according to a statement released by his family. The two-time Cup Series champion, 41, died on Thursday after a brief hospitalization with a “severe illness.”

“The medical evaluation provided to the Busch Family concluded that severe pneumonia progressed into sepsis, resulting in rapid and overwhelming associated complications,” read the statement, which was shared in a news release and reported by FOX Sports’ Bob Pockrass on Saturday.

Busch’s tragic case underscores the dangers pneumonia can pose, especially when left untreated or when symptoms quickly intensify.

NASCAR CHAMPION KYLE BUSCH’S CAUSE OF DEATH REVEALED BY FAMILY

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Pneumonia is a respiratory infection that fill the lungs with fluid, making breathing difficult. It can be caused by bacteria, viruses or fungi, according to multiple medical sources.

Symptoms typically include cough, fever, chills, chest pain and shortness of breath.

NASCAR star Kyle Busch’s cause of death was revealed Saturday as severe pneumonia that progressed into sepsis. (James Gilbert/Getty Images)

Busch reportedly had a sinus infection that worsened prior to his death. “This upper respiratory sinus infection progressed to pneumonia,” Fox News senior medical analyst Dr. Marc Siegel told Fox News Digital.

Bacterial pneumonia is normally more severe than viral pneumonia, according to Siegel.

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SURGE IN WALKING PNEUMONIA AFFECTS THESE HIGH-RISK GROUPS, SAYS DR. MARC SIEGEL

The doctor noted that the physical stress associated with racing simulators — which are designed to mimic the intense G-forces that drivers experience on the track — could potentially aggravate already inflamed lungs during recovery from pneumonia, though direct research on simulator-related effects is limited.

NASCAR Sprint Cup Series driver Kyle Busch stands with his wife Samantha Busch and son Brexton Busch prior to the Pennsylvania 400 at Pocono Raceway in August 2016 in Pennsylvania. (Matthew O’Haren-Imagn Images)

In severe cases, the infection in the lungs can spread into the bloodstream, triggering a widespread, life-threatening inflammatory response known as sepsis — particularly in vulnerable patients or when treatment is delayed, according to Siegel. 

Sepsis can quickly lead to tissue damage, organ failure and death if not treated right away.

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“The body reacts to this severe lung infection by making inflammatory chemicals – it’s the immune system revving up,” Siegel said. “But as with a lot of things with the body, the immune system can hurt more than help.”

As sepsis worsens, it can cause a drop in blood pressure and interfere with the delivery of oxygen to the body’s tissues, potentially leading to lactic acidosis — a dangerous buildup of lactic acid in the bloodstream.

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Organ failure is a serious risk, particularly affecting the kidneys, Siegel warned.

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“The kidneys fail, toxins from the kidneys build up, blood pressure goes down, fever goes up, the lungs fail — something called ARDS,” he said.

Kyle Busch celebrates his victory in the NASCAR Shelby 427 race at Las Vegas Motor Speedway in Las Vegas on March 1, 2009. (Isaac Brekken/AP)

ARDS — acute respiratory distress syndrome — occurs when inflammation causes fluid to leak into the lungs, making it difficult for oxygen to reach the bloodstream.

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Common warning signs of sepsis can include confusion, rapid breathing, extreme weakness, low blood pressure, fast heart rate, and bluish or mottled skin, per the CDC.

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Doctors emphasize that sepsis is a medical emergency because patients can deteriorate rapidly within hours.

Those at higher risk for severe pneumonia and sepsis include older adults and smokers, as well as those with chronic lung disease, diabetes, weakened immune systems or recent viral infections.

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Eili Lilly’s Retatrutide Weight-Loss Results Rival Bariatric Surgery

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Eili Lilly’s Retatrutide Weight-Loss Results Rival Bariatric Surgery


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Retatrutide Benefits for Weight Loss Rival Bariatric Surgery




















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