Health
Sperm donor with hidden cancer gene fathers nearly 200 kids, families blindsided
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A sperm donor whose samples helped conceive nearly 200 children across Europe unknowingly carried a cancer-causing genetic mutation — a hidden risk now tied to multiple childhood illnesses and early deaths.
An investigation led by the BBC and many other public service broadcasters revealed that the donations were made to Denmark’s European Sperm Bank (ESB). Those donations were then used by 67 fertility clinics in 14 countries over a 17-year span.
The donor, who was not identified, was paid to donate as a student beginning in 2005, according to the report.
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Although the donor passed the initial health screenings, he had hidden genetic mutations that damaged the TP53 gene, which helps to prevent cancer by repairing DNA damage or trigger the death of cancer cells.
When TP53 is mutated, those protective functions are lost, which can lead to uncontrolled cell division, accumulation of mutations and tumor growth, research has shown.
A sperm donor whose samples helped conceive nearly 200 children across Europe (not pictured) unknowingly carried a cancer-causing genetic mutation — a hidden risk now tied to multiple childhood illnesses and early deaths. (Getty Images)
Up to 20% of the man’s sperm would contain that mutated gene, and any children conceived from that affected sperm would have the mutation in every cell of their body, the BBC report stated.
As a result, these children would have a 90% risk of developing some type of cancer in their lifetime, including breast cancer, bone cancers, brain tumors and leukemia. This heightened risk is known as Li Fraumeni syndrome.
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Doctors raised these concerns at the annual congress of the European Society of Human Genetics (ESHG), which was held in Milan in May 2025.
At that conference, Edwige Kasper — a specialist in cancer genetics at Rouen University Hospital in France — presented the case of the sperm donor whose genetic material carried the harmful variant.
“This is the abnormal dissemination of genetic disease. Not every man has 75 children across Europe.”
It was reported that 23 children had been confirmed to have the variant at that time, 10 of which had already been diagnosed with cancer.
The actual number is likely much higher, the report surmised, as at least 197 children were born from the donated sperm — but not all data has been collected.
Kasper called for a limit on the number of births or families for a single donor in Europe.
“We can’t do whole-genome sequencing for all sperm donors — I’m not arguing for that,” she said. “But this is the abnormal dissemination of genetic disease. Not every man has 75 children across Europe.”
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She also recommended that children born from this donor’s sperm undergo genetic counseling.
“We have some children that have already developed two different cancers, and some of them have already died at a very early age,” Kasper recently told the investigators.
Up to 20% of the man’s sperm would contain that mutated gene, and any children conceived from that affected sperm would have the mutation in every cell of their body, the BBC report stated. (iStock)
There is no worldwide law that limits how many times a donor’s sperm can be used or how many children may be born from a single donor, according to the European Society of Human Reproduction and Embryology (ESHRE).
However, individual countries may have their own rules or guidelines surrounding sperm donor usage. The ESHRE recently proposed a cap of 50 families per donor as an international limit.
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Dr. Marc Siegel, Fox News senior medical analyst, commented on these developments to Fox News Digital.
“This awful story emphasizes the growing need for up-to-date genetic screening for all donors,” he said. “It also provides context for the idea that knowing the donor provides an advantage.”
“This awful story emphasizes the growing need for up-to-date genetic screening for all donors,” Dr. Marc Siegel said. (iStock)
“Genetic screening, including for oncogenes (genes that have the potential to cause cancer) is improving dramatically, and all use of sperm donations must include it,” Siegel went on.
He also called for AI to be used to improve and speed up the process.
“When a propensity for disease is suspected, the sperm must be discarded,” the doctor added.
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In a statement sent to Fox News Digital, the European Sperm Bank expressed “deepest sympathy” for the families involved.
“We are deeply affected by the case and the impact that the rare TP53 mutation has on a number of families, children and the donor. They have our deepest sympathy,” the ESP said.
The American Society of Reproductive Medicine provided its guidance on embryo and gamete donation, which stated in part that all prospective donors should undergo “appropriate genetic evaluation.” (iStock)
“ESB tests and performs an individual medical assessment of all donors in full compliance with recognized and scientific practice and legislation.”
In the case of this particular sperm donor with the TP53 mutation, the ESB noted that it occurs only in a small part of the donor’s sperm cells and not in the rest of the body.
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“In such cases, the donor himself and his family members are not ill, and a mutation of this type is not detected preventively by genetic screening,” the agency said.
When the ESB later confirmed the mutation in 2023, the donor was “immediately blocked” and authorities and clinics were notified.
“Donors should be healthy and have no history to suggest hereditary disease.”
“The clinics are responsible for informing the patients, partly because we as a sperm bank do not necessarily know the patients, and because the patients’ own treating physicians are best equipped to advise them in the specific situation,” the agency stated.
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When contacted by Fox News Digital, the American Society of Reproductive Medicine (ASRM) provided its guidance on embryo and gamete donation, which stated in part that all prospective donors should undergo “appropriate genetic evaluation.”
“Donors should be healthy and have no history to suggest hereditary disease,” the ASRM continued.
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Parents with concerns are encouraged to contact both their treating clinic and the relevant fertility authority in that country.
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Health
Cellphone health risks are focus of new government study: ‘Very concerned’
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The Department of Health and Human Services (HHS) is launching a study on whether radiation from cellphones could harm Americans’ health.
“The FDA removed web pages with old conclusions about cellphone radiation while HHS undertakes a study on electromagnetic radiation and health research to identify gaps in knowledge, including on new technologies, to ensure safety and efficacy,” HHS spokesperson Andrew Nixon said in a statement to Fox News Digital.
The study is part of a strategy report released last year by President Donald Trump’s MAHA Commission, Nixon added.
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The report urges officials to address electromagnetic radiation (EMR) exposure stemming from the widespread use of cellphones, Wi-Fi routers, cell towers and wearable, such as smartwatches.
In 2018, the National Institutes of Health did a study concluding there is “clear evidence” that high exposure to radio frequency radiation (RFR) was associated with cancer in male rats.
The HHS has launched a cellphone radiation study to investigate whether electromagnetic radiation is harmful to people’s health. (iStock)
“In our studies, rats and mice received RFR across their whole bodies. By contrast, people are mostly exposed in specific local tissues close to where they hold the phone,” said senior scientist John Bucher at the time.
Bucher added, “The exposure levels and durations in our studies were greater than what people experience.”
The study did not investigate the RFR that is used for Wi-Fi or 5G networks.
HHS Secretary Robert F. Kennedy Jr. told USA TODAY on Friday that “electromagnetic radiation is a major health concern,” adding that he is “very concerned about it.”
A spokesperson for CTIA, the mobile carrier industry trade group, told Fox News Digital there is no credible evidence linking wireless devices to health problems.
“The FDA removed web pages with old conclusions about cellphone radiation while HHS undertakes a study on electromagnetic radiation and health research to identify gaps in knowledge, including on new technologies, to ensure safety and efficacy,” said an HHS spokesperson. (iStock)
“Radiofrequency energy from Wi-Fi and Bluetooth devices, mobile phones and wireless infrastructure has not been shown to cause health problems, according to the consensus of the international scientific community and independent expert organizations around the world,” said the spokesperson.
The World Health Organization has noted on its website that research shows “no adverse health effect has been causally linked with exposure to wireless technologies.”
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In the U.S., cellphones must comply with Federal Communications Commission (FCC) limits on radiofrequency (RF) exposure.
The FCC uses a metric called specific absorption rate (SAR), which tracks how much RF energy the body absorbs. To be sold in the U.S., mobile phones and similar wireless devices must be tested and certified to ensure that they do not exceed 1.6 W/kg (watts per kilogram), averaging over 1 gram of tissue.
In the U.S., cellphones must comply with Federal Communications Commission (FCC) limits on radiofrequency (RF) exposure. (iStock)
The FCC states on its website that there is “no scientific evidence currently establishing a definitive link between wireless device use and cancer or other illnesses.”
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However, the agency does share ways that Americans can reduce exposure — such as shortening the amount of time spent on wireless devices, putting a phone on speaker or using an earpiece “to reduce proximity to the head and thus head exposure.”
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The FCC also recommends increasing the distance between wireless devices and the body, and texting instead of talking when possible.
Fox News Digital reached out to HHS and NIH for additional comment, as well as several major cellphone carriers.
Health
Dozens sickened as potentially deadly fungus spreads in southern state
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A potentially deadly fungus has been spreading throughout Tennessee, health officials have warned.
Over 35 cases of histoplasmosis, a lung infection caused by exposure to the fungus Histoplasma capsulatum, have been confirmed in a three-month period in the Murray and Williamson County area, according to numbers presented on Jan. 12 by the Tennessee Department of Health.
A family has also spoken out with claims that one woman died after contracting histoplasmosis, with a positive test result returned two days after her death, according to a local report.
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However, during a briefing at the Williamson County Board of Commissioners, state epidemiologists said an investigation is underway and that the infection has not yet been confirmed as the direct cause of any fatalities.
They also noted that the average age of those infected is 50.
Histoplasmosis is a lung infection caused by exposure to the fungus Histoplasma capsulatum. (iStock)
The fungus comes from soil that is contaminated with bird or bat droppings, according to state officials. People are exposed when they breathe in the fungal spores. A single common source has not been identified in the Tennessee outbreak.
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In most cases, people don’t get sick, but there is the potential for histoplasmosis to cause respiratory symptoms, ranging from mild to life-threatening, per the CDC.
Symptoms of histoplasmosis — which can include fever, cough, extreme fatigue, headache, body aches, chills and chest pain — typically emerge within three to 17 days after exposure to the fungus.
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Because these symptoms are similar to the cold and flu, the condition is often missed or misdiagnosed.
People with weak immune systems are at a higher risk of developing severe illness, which can lead to a long-term lung infection or, in rare cases, meningitis, per the CDC.
While most people do not require treatment, there are antifungal medications for severe cases. Some of the Tennessee patients have been hospitalized and some are “critically ill,” the state officials confirmed during the briefing.
State officials confirmed there have been 35 cases over a three-month period in the Murray and Williamson County area. (iStock)
Healthcare providers can confirm the infection by testing blood or urine samples in a lab. Other possible means of testing may include respiratory fluid, X-rays, CT scans or a tissue biopsy.
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To prevent infection, health officials recommend limiting activities where soil is disturbed and to consider wearing masks during “high-risk” outdoor activities.
Healthcare providers can confirm the infection by testing blood or urine samples in a lab. Other possible means of testing may include respiratory fluid, X-rays, CT scans or a tissue biopsy. (iStock)
Before this outbreak, histoplasmosis was a “reportable disease” in only 14 states (Arkansas, Delaware, Illinois, Indiana, Kansas, Kentucky, Louisiana, Michigan, Minnesota, Nebraska, Pennsylvania, Rhode Island, Wisconsin and Washington), according to the CDC.
The infection does not spread between humans and cannot be transmitted from humans to animals.
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Anyone who experiences symptoms and believes they have been exposed to the Histoplasma fungus should contact a doctor for testing, especially if antibiotics are not helping.
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