Health
Some supplements may pose risks for people with diabetes, experts say
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Some surveys find that about 75% of U.S. adults have used supplements, while federal survey data shows that 58% used one in the past 30 days — but some groups should exercise caution, experts say.
There are many different supplements — including vitamins, minerals, herbs, amino acids and probiotics — designed to fill nutrient gaps and support overall wellness. Some target specific functions, such as immune support, muscle recovery and bone health, according to multiple medical sources.
Unlike prescription drugs and over-the-counter medications, supplements usually aren’t FDA-approved before they are marketed, but the FDA does regulate them and can take action against unsafe or misbranded products.
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For people with diabetes, the following supplements could pose serious health risks, as they can affect blood glucose levels or interact with medications, per the National Institutes of Health.
Unlike prescription drugs and over-the-counter medications, supplements usually aren’t FDA-approved before marketing. (iStock)
St. John’s Wort
Dawn Menning, a California-based registered dietitian and certified diabetes care and education specialist with Nutu, a healthy lifestyle app, says people with diabetes should avoid taking St. John’s Wort as a supplement.
Primarily touted as a natural remedy for mild to moderate depression, St. John’s Wort could have additional benefits for anxiety, sleep issues, and menopausal or PMS-related symptoms.
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“This herbal remedy can interfere with many diabetes medications by affecting the way the body breaks them down,” Menning told Fox News Digital. “This can make medications less effective and blood sugar management more difficult.”
Chromium
This supplement is often marketed for its ability to improve blood sugar regulation in people with type 2 diabetes, Menning noted, but there is limited evidence and the research is “mixed.”
“Taking this supplement with insulin or oral diabetes medications may increase the risk of hypoglycemia,” she cautioned. This condition can increase the risk of dizziness, fatigue and fainting, according to Healthline.
For people with diabetes, some supplements could pose health risks, as they can affect blood glucose levels or interact with medications (iStock)
Bitter melon supplements
These are often taken to help with reducing blood sugar levels in people with diabetes, Menning noted.
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“It contains compounds such as polypeptide-p, which may act like insulin,” she said. “Taking this with diabetes medications could increase the risk of hypoglycemia.”
Niacin (vitamin B3)
This supplement is sometimes used to help manage cholesterol levels — but in people with diabetes, it may also raise blood sugar levels, increasing the risk of hyperglycemia (high blood sugar).
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“I would caution against using high-dose niacin supplements because it can noticeably raise blood sugar levels and make it harder to keep A1c in an optimal range,” Michelle Routhenstein, preventive cardiology dietitian at EntirelyNourished.com in New York, told Fox News Digital.
Ginseng
Asian ginseng has been linked to a boost in energy, focus and immune system health. It also contains antioxidants, which can provide cellular protection, according to Cleveland Clinic.
While it has also been linked to improved cardiometabolic factors for those with prediabetes and diabetes, some evidence suggests that ginseng could lower blood sugar levels when combined with diabetes medications.
Β-carotene
This supplement is primarily used as an antioxidant and a source of vitamin A to support vision, immune function, and overall eye and skin health.
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“The American Diabetes Association recommends against β-carotene supplementation for people with diabetes because of its association with increased lung cancer and cardiovascular mortality risk,” Jordan Hill, a registered dietitian with Top Nutrition Coaching in Colorado, told Fox News Digital.
High-dose cinnamon (Cassia cinnamon)
Cinnamon is often promoted as a supplement for diabetes management and weight loss, as some research has shown it can help to reduce blood sugar and lower insulin resistance.
For most supplements, one expert said, “there isn’t evidence to support a beneficial effect on diabetes or its complications.” (iStock)
However, consuming large amounts of cinnamon can enhance the effects of diabetes and cause blood sugar levels to fall too low, which can cause hypoglycemia, Healthline warns.
Cinnamon also includes a compound called coumarin, which can cause liver damage if consumed in large amounts.
Niacin (high-dose vitamin B3)
This supplement can help to promote healthy digestion, skin and nervous system function, according to Mayo Clinic.
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High doses of nicotinic acid (a form of niacin) can raise blood sugar levels and interfere with the effectiveness of diabetes medications, warns the National Institutes of Health.
“These doses can even raise blood sugar levels in people who don’t have diabetes,” the NIH states.
Aloe vera
Oral aloe vera is often promoted for diabetes, weight loss and inflammatory bowel disease.
However, when paired with diabetes medications, it could cause blood sugar levels to dip and increase the risk of hypoglycemia with medications, according to the National Institutes of Health. It can also cause gastrointestinal side effects.
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For most supplements, Menning noted, “there isn’t evidence to support a beneficial effect on diabetes or its complications.”
“The primary concern with most supplements is not direct harm, but rather the lack of regulatory oversight.”
The American Diabetes Standards of Care state: “Without underlying deficiency, there are no benefits from herbal or nonherbal (i.e., vitamin or mineral) supplementation for people with diabetes.”
The American Association of Clinical Endocrinology advises caution with all unregulated nutritional supplements due to “inconsistent composition, quality and potential for harm,” Hill said.
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“The primary concern with most supplements is not direct harm, but rather the lack of regulatory oversight,” he told Fox News Digital.
Experts recommend speaking with a doctor before starting any supplement to understand how it could affect blood sugar levels, medications or overall diabetes management.
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Eliminating sugar from your diet may seem like the key to healthy eating, but research suggests it could have unintended effects on digestive health.
A study presented at ENDO 2026, the Endocrine Society’s annual meeting, suggests that a total lack of sucrose, or table sugar, may harm gut health and disrupt the body’s natural metabolism.
To explore how the total absence of dietary sugar impacts the body, researchers at the Dasman Diabetes Institute in Kuwait City conducted a 16-week study on two groups of mice. Both groups were placed on a low-fat diet, but with one critical difference.
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One group consumed a low-fat diet that included a standard amount of sucrose, while the other group ate a low-fat diet that was completely sugar-free, according to the study’s press release.
Throughout the trial, the scientists monitored a wide variety of physiological factors, including the animals’ weight, glucose tolerance, insulin sensitivity, hormone levels, internal inflammation and the specific composition of their gut bacteria.
A total lack of dietary sugar can cause imbalances in the gut bacteria and lead to signs of fatty liver disease, even without any weight gain, researchers said. (iStock)
The study outcome suggested that completely removing sugar caused several unexpected health problems.
“Completely removing sucrose from a low-fat diet may unexpectedly disrupt gut health and promote inflammation and metabolic dysfunction,” Rasheed Ahmad, principal scientist and head of the Immunology & Microbiology Department at the Dasman Diabetes Institute, said in the release.
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Even though the mice on the sugar-free diet did not gain any extra weight compared to the control group, their internal health indicators deteriorated.
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The animals that lacked sucrose developed an imbalance in their gut microbes and increased inflammation within the intestines and liver.
They also showed signs of poor glucose regulation, insulin resistance and cellular changes associated with fatty liver disease, according to the research.
Future dietary guidelines may shift away from strict, absolute sugar bans and instead focus on overall gut health through balanced nutrition. (iStock)
“The findings suggest that complete removal of sucrose from a low-fat diet may negatively affect gut microbiota and metabolic health,” Ahmad concluded.
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While the risks of high-sugar diets are well-established, the researchers noted that little attention has been given to the effects of completely eliminating sugar from low-fat meals.
Scientists say these new findings highlight that dietary carbohydrates play a valuable role in supporting balance between the immune system and the gut microbiome.
Completely cutting sucrose from a low-fat diet can unexpectedly trigger gut inflammation and disrupt the metabolism, experts say. (iStock)
Because this research was conducted on mice over a relatively short 16-week period, further clinical trials are necessary to determine whether a completely sugar-free diet causes the same gut and liver inflammation in humans.
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Additionally, the study focused specifically on removing sucrose from low-fat meals, meaning the results might not apply to people eliminating sugar while following higher-fat or ketogenic eating plans, the researchers noted.
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The team believes that future dietary guidelines may shift away from strict, absolute sugar restrictions and instead place a greater emphasis on maintaining a diverse, healthy population of gut bacteria through balanced nutrition.
“In the long term, these findings could help improve strategies for preventing and managing metabolic disorders, fatty liver disease and chronic inflammatory conditions,” Ahmad said.
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A cure for cancer could be on the horizon in the next decade, according to experts.
During the WSJ Leadership Institute CEO Summit in London last week, Johnson & Johnson Chairman and CEO Joaquin Duato reflected on the pharmaceutical company’s projections on the future of cancer treatment.
In the next 10 years, the goal is to “try to eliminate cancer,” Duato shared.
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“That’s a high goal, and we are already making significant progress in certain cancers,” he said.
Duato used multiple myeloma as an example, noting that the life expectancy is currently 10 years, when it was previously “only single years.”
Joaquin Duato, chairman and CEO of Johnson and Johnson, speaks at the Punchbowl News Conference at Union Station on March 10, 2026, in Washington, DC. (Heather Diehl/Getty Images)
“We have treatments now that utilize your own immune system to attack the cancer,” he said at the summit. “For patients who were already going into hospice, so they didn’t have any other alternative, they are [at] more than five years, with a single administration, in remission. That [is] spectacular.”
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“When patients see that, they cannot believe that because they have been coming to the hospital every week [for] a decade, having multiple therapies.”
The goal is to “try to eliminate cancer” in the next 10 years, the pharmaceutical executive said. (iStock)
According to Duato, Johnson & Johnson is working to understand the biology of cancer growth and to formulate new technologies to address it.
“It’s realistic to believe that we are going to cure certain cancers, and some others we’re going to turn into chronic diseases,” he predicted.
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“Cancer is an important thing – I cannot think about anybody who has not been touched by cancer,” he went on. “But there are many other opportunities for us to actually advance science, to address very important social problems.”
Duato called out dementia as another “important problem” in need of a solution.
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He predicted that life expectancy, which has risen steadily over the past century, will continue to increase as longevity technologies and solutions advance, improving quality of life along the way.
Duato commented that J&J has been optimistic about the role artificial intelligence will play in the future of healthcare, calling it a “force multiplier.”
Biomarkers and AI can help with the earlier diagnosis of cancer, as well as a more advanced and personalized approach to surgery, a doctor noted. (iStock)
Fox News senior medical analyst Dr. Marc Siegel agreed with Duato’s outlook on the future of cancer care, noting that certain cancers will turn into chronic diseases while others will find outright cures.
“Advances [will be] based on the use of AI to help guide targeted treatments with expanding knowledge of cancer mutations and how to target them,” he predicted, speaking to Fox News Digital.
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Siegel added that biomarkers and AI can help with earlier diagnoses, as well as a more advanced and personalized approach to surgery.
J&J recently acquired Firefly Bio, a biotech firm that produces drugs that enter cancer cells to “target certain proteins that contain difficult to treat gene mutations,” the doctor added.
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