Health
Scientists unveil ‘living bandage’ that could dramatically speed wound healing
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A new “living bandage” could soon revolutionize how doctors treat serious injuries by accelerating the healing process, according to new research reported by SWNS.
The high-tech patch was developed by researchers at Rice University in Texas. It acts like an around-the-clock mini factory, continuously delivering healing proteins directly to different types of wounds, the same source noted.
Caring for chronic wounds is often a challenge for doctors, as it’s difficult to deliver steady, localized signals that tell the body to repair its own tissue, the researchers said.
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The body naturally relies on small chemical messengers called cytokines to control inflammation and healing. However, traditional treatments like ointments or injections usually fail, as fragile proteins break down too quickly or wash away from the injury site.
To solve the problem, the research team created a cell-based patch that stays on top of the wound. Inside the device, scientists placed engineered cells programmed to manufacture and secrete three specific healing cytokines, known as IL-10, IL-12 and Transforming Growth Factor-beta.
A living bandage patch delivers healing proteins from engineered cells to accelerate wound healing, according to new research by American scientists. (Jared Jones/Rice University/SWNS)
These cells are safely housed inside protective material that acts like a shield — letting vital nutrients and therapeutic proteins pass through to the skin while keeping the body’s immune system from attacking the engineered cells inside.
The system also uses a special hydrogel that helps the patch blend naturally with the wound, SWNS reported. It may be updated eventually, the research team indicated, to work alongside electronic components.
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In lab tests on rodents and pigs, the patch successfully accelerated wound healing. By analyzing the genetic material of the cells, the researchers confirmed the treatment successfully activated the processes needed for tissue repair.
Professor Omid Veiseh, faculty director of the Rice Biotech Launch Pad and leader of the laboratory development, said the animal trials showed strong potential for the approach.
“By maintaining a consistent presence of these signaling molecules at the wound site, we can more effectively engage the body’s natural healing response,” the scientists said. (iStock)
“The findings show how continuous, localized cytokine delivery can support key biological pathways involved in tissue repair,” Veiseh said, according to SWNS.
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“By maintaining a consistent presence of these signaling molecules at the wound site, we can more effectively engage the body’s natural healing response.”
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He said genetic analysis “revealed coordinated upregulation of genes associated with tissue regeneration and immune modulation, providing a mechanistic basis for the functional improvements observed.”
Researcher Elizabeth Kelley of Rice University holds a cytokine-secreting patch designed to accelerate wound healing by delivering healing proteins from engineered cells continuously. (Jared Jones/Rice University/SWNS)
The platform is fully customizable, so the engineered cells can easily be adapted to produce different combinations of proteins and growth factors, depending on what each individual patient needs.
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Study co-author Christian Schreib, Ph.D., noted that “the ability to tune both the type and timing of cytokine delivery opens the door to more precise control over the healing process.”
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Schreib said that “future work will focus on expanding the flexibility of the platform, including approaches such as optogenetic control” — using light to control cell activity — “to regulate cytokine secretion in real time.”
The technology is still in an early stage and has not yet been tested on human patients.
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Further research is needed to understand how the technology will be used on humans.
The study was published in the journal Nature Biomedical Engineering.
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Health
Drinking alcohol may influence cravings for certain foods in a surprising way, study suggests
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If you find yourself reaching for a bag of chips after a few drinks, hormones may be partly to blame. Researchers suggest they can influence food cravings and may contribute to significant overeating.
Studies examining how alcohol affects people’s eating habits have produced inconsistent results, University of Sydney researchers reported in Obesity Reviews.
Alcohol on its own always adds calories, but how much it contributes to people’s total caloric intake depends on their dietary habits, the scientists observed.
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Previous research suggests alcohol consumption may increase levels of FGF21, “a hormone that increases savory (umami) preference and reduces sweet preference,” the researchers wrote. In “minimally processed food environments,” people seek foods that are both satiating and high in protein, and they limit the number of calories they eat.
On diets rich in ultra-processed savory foods and/or high-fat unprocessed meats, however, consumers eat foods that taste like the minimally processed foods, but that fail to deliver protein. The researchers refer to these foods as “protein decoys.” People who indulge in ultra-processed foods tend to eat many more calories, because they’re not satisfied without protein.
Researchers have observed that alcohol stimulates a hormone that causes people to crave savory foods and could lead them to overindulge in highly-processed foods. (iStock)
The researchers analyzed previous experimental work that involved interviews with more than 9,000 Australians. The survey found that people who reported drinking alcohol also reported eating a lot more savory foods and fewer sweet foods than the non-drinkers. People’s savory food intake increased on days they reported drinking.
People who reported drinking and consuming a savory diet with the low-protein, high-fat characteristics of an ultra-processed diet took in 40% more calories than the daily recommendation — before factoring in the alcohol.
“Results suggest that alcohol may have contributed to the obesity epidemic,” because it increases people’s appetites, and people consuming highly processed foods eat more of the unsatiating food, the researchers hypothesized.
The researchers wrote that their observations could explain why studies on alcohol’s effect on caloric intake have been so varied, because it likely depends on the types of foods you’re eating while drinking.
They also noted that their studies did not directly measure FGF21 levels, but that they applied previous information gathered through scientific studies to make their observations. They wrote that they could not provide direct evidence of FGF21’s role in food intake.
Many people crave savory foods when they’re drinking alcohol, but the type they consume can have a major impact on caloric intake, researchers theorize. (iStock)
The researchers also acknowledged the limitations of their research, since it was largely based on secondary evidence from a population survey.
“Advice to limit highly processed foods, including savory snack foods, may be even more critical than previously thought for reducing the risk of weight gain among adults who drink regularly,” they concluded.
Registered dietitian Morgan Beemiller, RD, LDN, based in Ohio, said she was not surprised by this study’s findings.
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“Alcohol is known to affect several biological and behavioral systems that influence food cravings,” she told Fox News Digital.
According to Beemiller, alcohol alters appetite-regulating signals and affects the brain’s reward circuits. It also changes taste perception, she said.
To avoid the ultra-processed overeating pitfall, Beemiller recommended people eat a substantial meal prior to drinking.
“Include protein, fiber-rich carbohydrates and healthy fats,” she advised. “This combination helps slow alcohol absorption and reduces urges for convenience foods later.”
People who consumed highly-processed foods while consuming alcohol took in 40 percent more than the recommended daily number of calories, one study found. (iStock)
Chicken, rice and salad or salmon, potatoes and broccoli are sensible pre-drink meals, Beemiller said.
“Decide on your late-night food before you start drinking,” she said. “If healthy food is already available, you are less likely to order or make convenience foods later in the evening.”
People should keep minimally processed snacks such as nuts, cheese, fruit, hummus and vegetables and hard-boiled eggs, readily available, Beemiller said. It’s also important to stay hydrated, she noted. Alternating alcoholic drinks with water can reduce total alcohol consumption, improve hydration and reduce hangover symptoms.
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While Beemiller said evidence suggests less alcohol is generally better for health, she added there are a few ways to reduce the negative impact if someone chooses to drink.
Keep your intake to a moderate level. Health risks rise the more people drink. Choose low-sugar options such as dry wines, light beers and cocktails that use fresh juices rather than syrups. Avoid high-sugar drinks, such as margaritas, daiquiris, sweet dessert wines and hard lemonades. Also beware of high-calorie mixers. Opt for sparkling water instead.
“Choose alcohol for enjoyment, not stress management,” Beemiller said.
Health
Can alkaline water actually improve your health? Experts separate fact from fiction
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Alkaline water has entered the conversation as an arguable alternative to regular drinking water.
Numerous celebrities, including Gwyneth Paltrow, Mark Wahlberg and Jennifer Aniston, have touted alkaline water in brand campaigns — but is there a real benefit? Experts report that the science is uncertain.
Bottled water that’s sold as alkaline water may have added minerals like calcium and magnesium, which help the water reach an alkaline pH, according to Mayo Clinic. A pH of 7 is neutral, while a level greater than 7 is alkaline and less than 7 is acidic.
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Plain tap water has a lower pH than alkaline water, which has led some to claim that drinking alkaline water can neutralize acidity in the body.
There have also been claims that alkaline water can help prevent certain health conditions, like cancer and stroke, Mayo Clinic mentioned. Some studies have also shown that alkaline water may help slow bone loss, perhaps due to the added calcium.
Bottled water that’s sold as alkaline water may have added minerals like calcium and magnesium, which help the water reach an alkaline pH, according to Mayo Clinic. (iStock)
Other research suggests that alkaline water combined with a plant-based Mediterranean diet may help relieve acid reflux. Several studies have suggested that alkaline water alone could improve symptoms of gastroesophageal reflux disease (GERD).
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Mayo Clinic stressed that more research is necessary to support these claims and to confirm whether these benefits continue over time.
In a Harvard Medical School publication, Howard E. LeWine, MD, chief medical editor of Harvard Health Publishing, confirmed that benefits potentially exist, but only temporarily.
Any benefits of alkaline water are temporary, according to an expert from Harvard Health. (iStock)
“Because the fluid in the stomach is so acidic, once regular or alkaline water gets down to your stomach, there will be little difference in the resulting stomach fluid pH,” he wrote.
“You could potentially raise the stomach fluid pH by drinking a lot of alkaline water, but it would only be temporary. Even if you drank enough alkaline water to slightly raise the pH of your blood, your kidneys would quickly go into action to rebalance your blood pH.”
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As an example, alkaline water may provide heartburn relief from acid reflux, but the effects would not be long-lasting. LeWine considered that there are “much more effective options,” such as antacids.
The doctor warned that drinking alkaline water could be dangerous for people who take PPIs, or stomach acid production blockers.
Experts warn that drinking alkaline water may raise pH to dangerous levels. (iStock)
Mayo Clinic added that alkaline water has been linked to safety concerns, especially when the water’s pH is higher than 9.8. This can lead to high levels of potassium in the blood, a condition known as hyperkalemia.
LeWine expressed the same concern that alkaline water “might result in an increased blood pH, which can alter the normal blood levels of chemicals like potassium, especially [for people with] kidney disease.”
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In an interview with Fox News Digital, certified holistic nutritionist Robin DeCicco confirmed that there is “no strong evidence” that alkaline water provides “meaningful long-term health benefits.”
Lowering acidity in the body is “really about foundational healthy habits at the end of the day,” a nutritionist said. (iStock)
While infusing the water with minerals can be beneficial for reducing acidity in the body, the best way to do so is by following “foundational” dietary habits, according to the expert.
This includes eating meals based in real foods and eliminating excess sugar, caffeine, processed and fried foods, as they can “aggravate acidity in the body,” she said.
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“Vegetables, fruit, good fats, like the omega-3 fats, lean protein, fiber — those are the things that really help to keep acid out of the body,” DeCicco added.
For those who have acid reflux complications, she recommends seeing a doctor and adopting helpful habits like eating consistently throughout the day, not lying down after eating and avoiding highly acidic foods.
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