Health

President Trump’s Cuts to Medical Research

Published

1 year ago

February 25, 2025

President Trump’s Cuts to Medical Research

The Trump administration stormed into office, loudly firing workers and closing diversity programs. But behind the scenes, it has also brought biomedical research to the brink of crisis by holding up much of the $47 billion the United States spends on the field every year.

The world’s leading medical labs can be found in the United States, and they rely on grants from the National Institutes of Health. The agency has stopped vetting future studies on cancer, Alzheimer’s, heart disease and other ailments. Trump aides have said they just need time to review spending their predecessors had promised, but it’s unclear what they’re looking for at the N.I.H. or when scholars can expect to start receiving money again.

In today’s newsletter, I’ll walk you through what happened — and why it matters.

A complex machine

Late last month, when the Trump administration froze government grants, a federal judge said it couldn’t just hold back money Congress had agreed to spend. But spending money at the N.I.H., which awards more than 60,000 grants per year, isn’t so simple.

That’s because new grants endure a tortured bureaucratic process. The agency has to notify the public of grant review meetings in The Federal Register, a government publication. Then scientists and N.I.H. officials meet to discuss the proposals. The problem is that the Trump administration banned those announcements “indefinitely.” So new research projects can’t get approved.

In effect, scientists say, the Trump administration is circumventing the court order. Health officials didn’t block research outright, but by shutting down the process, they’re still not spending much of the money Congress allocated to various research goals.

The administration has also proposed other big changes, saying that universities should bear more of the “indirect costs” of research: maintaining lab space, paying support staff. Trump aides say the changes would trim administrative bloat and free up more government money for research.

Labs hit pause

Scientists are panicked, and hundreds of studies are at a standstill, including ones on pancreatic cancer, brain injuries and child health. Last week alone, the N.I.H. canceled 42 of 47 scheduled meetings to assess new grants. Some examples of stalled projects:

For years, Steffanie Strathdee at the University of California San Diego has followed drug users to research overdoses, which kill some 100,000 people in the United States each year. Her investigation of H.I.V. infections in that group was ready to begin — but came to an abrupt halt when the N.I.H. canceled a review panel meeting this month. “Everything is absolutely frozen,” she told me. “It’ll just sit there, hanging in limbo.”
Anthony Richardson at the University of Pittsburgh was expecting a review panel to weigh a grant application of his on staph infections in people with diabetes, a disease that afflicts more than one-tenth of Americans. It never happened. “I am not 100 percent sure what their motives are,” he said.

In response to all the uncertainty, universities are retrenching. The University of Pittsburgh froze Ph.D. admissions. Columbia University’s medical school paused hiring and spending. The Massachusetts Institute of Technology froze the hiring of nonfaculty employees.

Some lab leaders told me they were making contingency plans to fire scientists. Graduate students are searching for new sources of funding.

What next?

It’s hard to say how long the holdup will last. The Trump administration hasn’t submitted a single new grant review meeting to The Federal Register since a day after it took office. And even if it started adding new ones, the agency traditionally gives several weeks’ notice.

At risk are not only the tens of thousands of grants the N.I.H. awards each year, but also American dominance of biomedical research. Every dollar the agency spends on research generates more than two dollars in economic activity, the N.I.H. has said. Scores of patents follow. By some measures, the United States produces more influential health-sciences research than the next 10 leading countries combined.

The science unfolds across the country, including in red states, where lawmakers have complained about proposed changes to indirect costs.

Those findings often fuel pharmaceutical advancements, laying a foundation for drugs and vaccines long before private funders see such work as worth investing in.

Even Ozempic traces its roots back in part to work at the N.I.H on animal venom. Scientists found that the toxin from Gila monster lizards seemed to have particular physiological effects, helping lead eventually to one of the world’s most profitable and promising drugs.

New advances like those, scientists say, are in danger.

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Dementia risk signals could lie in simple blood pressure readings, researchers say

Published

9 hours ago

March 27, 2026

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Dementia risk signals could lie in simple blood pressure readings, researchers say

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Simple measurements taken during routine blood pressure checks could predict dementia risk years before symptoms appear.

That’s according to new research presented this week at the American College of Cardiology’s Annual Scientific Session in Louisiana.

The findings draw on two studies led by researchers at Georgetown University, which suggest that monitoring how blood vessels age and stiffen over time can provide a window into future cognitive health.

LURKING DEMENTIA RISK EXPOSED BY BREAKTHROUGH TEST 25 YEARS BEFORE SYMPTOMS

Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age, and half of U.S. adults have high blood pressure (hypertension).

Scientists believe that efforts to better address hypertension, a key contributor to heart disease and a risk factor for dementia, could affect both cardiac and brain health.

Data shows rates of dementia and aging-related cognitive decline are expected to increase as populations age. Meanwhile, half of U.S. adults have high blood pressure. (iStock)

“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health,” Dr. Newton Nyirenda, the study’s lead author and an epidemiologist at Georgetown University in Washington, said in a press release.

The research focused on two metrics, the pulse pressure-heart rate index and estimated pulse wave velocity. Both were calculated using data collected during standard doctor visits, such as heart rate, age and blood pressure.

“Blood pressure management isn’t just about preventing heart attacks and strokes; it may also be one of the most actionable strategies for preserving cognitive health.”

Researchers examined five years of data patterns for more than 8,500 people in the SPRINT trial, a large study of adults 50 years and older with hypertension. In the follow-up, 323 of the participants developed probable dementia.

HIDDEN BRAIN CONDITION MAY QUADRUPLE DEMENTIA RISK IN OLDER ADULTS, STUDY SUGGESTS

In one study, the team found the pulse pressure-heart rate index was a strong independent predictor of dementia risk in adults over 50. For participants under 65, every one-unit increase was associated with a 76% higher risk of developing dementia.

For participants under 65, an increase in the pulse pressure-heart rate index was associated with a 76% higher risk of developing dementia. (iStock)

The second study found that adults with consistently elevated or rapidly increasing pulse wave velocity were more likely to develop dementia than those with stable velocity, even after accounting for factors like smoking, gender and cardiovascular history.

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“Our findings suggest that vascular aging patterns may provide meaningful insight into future dementia risk,” said Nyirenda. “This reinforces the idea that managing vascular health earlier in life may influence long-term brain health.”

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The team emphasized that clinicians should tailor risk assessments and treatment strategies to the individual.

Further studies are needed to confirm these parameters and determine whether changing vascular aging trajectories reduces dementia risk. (iStock)

“You don’t want to wait until a patient starts manifesting cognitive decline before you act,” said senior study author Sula Mazimba, an associate professor at the University of Virginia.

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Researchers noted the study could not establish causation. Other limitations included the fact that participants already had hypertension and elevated cardiovascular risk, meaning the findings may not apply to people without those conditions.

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Further studies are needed to confirm these findings and to determine whether improving blood vessel health over time could reduce dementia risk.

Khloe Quill is a lifestyle production assistant with Fox News Digital. She and the lifestyle team cover a range of story topics including food and drink, travel, and health.

Health

Everything You Need To Know About Zepbound for Weight Loss, Including Costs

Published

20 hours ago

March 26, 2026

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Everything You Need To Know About Zepbound for Weight Loss, Including Costs

What Is Zepbound? Weight-Loss Benefits, Costs and Dosage

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Health

‘Gas station heroin’ banned in another state amid nationwide crackdowns

Published

21 hours ago

March 26, 2026

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‘Gas station heroin’ banned in another state amid nationwide crackdowns

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A dangerous substance dubbed “gas station heroin” continues to alarm medical professionals, with more states making moves to restrict or ban tianeptine.

Fourteen states have officially classified the tricyclic antidepressant as a Schedule I controlled substance.

Connecticut is the latest state to crack down, officially banning the sale and use of the substance starting on Wednesday.

HEALTH OFFICIALS WARN OF DANGEROUS SUBSTANCE AVAILABLE IN STORES ACROSS THE NATION

Tianeptine, which can produce euphoria in higher doses, can be more potent than morphine and addictive opioids, according to the U.S. Food and Drug Administration.

Some countries have taken steps to restrict how tianeptine is prescribed or dispensed, and have even revised the labels to warn people of its potential addictive qualities.

Tianeptine can be more potent than morphine and addictive opioids. (iStock)

Misuse of tianeptine can cause severe adverse health effects, including respiratory depression, severe sedation and death, according to the Drug Enforcement Administration.

Some companies market the drug as an aid for pain, anxiety and depression, or as a means of improving mental alertness in a pill, powder, salt or liquid form.

The products are typically sold at convenience stores, gas stations, vape shops and online retailers, and go by names like Tianaa, ZaZa, Neptune’s Fix, Pegasus and TD Red.

Connecticut is the 15th state to classify tianeptine as a Schedule I controlled substance. (Markus Scholz/picture alliance via Getty Images)

Connecticut Lt. Gov. Susan Bysiewicz said in a press release that the schedule change is a necessary step to combat addiction.

“With false marketing that led consumers to believe these are safe products, and with candy-like flavor options, these substances posed a clear threat to those battling substance-use disorder and our youngest residents,” she added.

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The Nutmeg State also added Mitragyna speciosa (kratom), 7-hydroxymitragynine, Bromazolam, Flubromazolam, Nitazenes and Phenibut to the schedule classification.

Earlier this month, FDA Commissioner Martin Makary penned a letter sounding the alarm on what he called a “dangerous and growing health trend.”

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“I am very concerned,” Makary wrote. “I want the public to be especially aware of this dangerous product and the serious and continuing risk it poses to America’s youth.”

New York-based Robert Schwaner, M.D., vice chair of system clinical affairs at Stony Brook Emergency Medicine, told Fox News Digital that the FDA has never approved tianeptine as a dietary supplement.

“As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.” (Dekalb County Sheriff’s Office)

“The euphoria at low doses is primarily due to increased serotonergic activity from its serotonin reuptake effects. With increasing doses, the mu-opioid receptor stimulation may become lethal,” said Schwaner. “As with heroin and other opioids, significant mu-opioid receptor stimulation ultimately results in a loss of respiratory drive and subsequent cardiac arrest.”

Schwaner said he believes the substance requires national regulation due to its addictive qualities.

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“Acting at the same receptor as opioids, tianeptine has the potential for an individual to develop tolerance, subsequent dependence and withdrawal from its use,” he cautioned.

Fox News Digital reached out to the FDA for comment.

Fox News Digital’s Greg Wehner and Melissa Rudy contributed to this report.

Ashley J. DiMella is a lifestyle reporter with Fox News Digital.